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Tommasi

Allesandro Tommasi, Viareggio IT

Patent application numberDescriptionPublished
20080222635Method for Runtime Execution of One or More Tasks Defined in a Workflow Process Language - Runtime execution of one or more tasks defined in a workflow process language. The method may include obtaining a description of the task from a process ontology (PO). The PO may define a hierarchical taxonomy of executable tasks, where each task refers to at least one frame of a hierarchical frame taxonomy of the PO. The method may further include identifying at least one parameter as described in the frame description to which the task refers, resolving the value of the at least one parameter, and executing the most specific applicable version of the task contained in the task taxonomy of the process ontology.09-11-2008

Gabriele Tommasi, Cavezzo (mo) IT

Patent application numberDescriptionPublished
20090012443VENOUS BLOOD RESERVOIR IN AN EXTRACORPOREAL CIRCUIT - A vacuum assisted venous blood reservoir has a controller that can sense pressure within a sealed blood chamber. The controller regulates the amount of vacuum within the chamber to control the level of blood in the venous reservoir. A safety valve is included to prevent blood from entering the vacuum line.01-08-2009

Ruben Tommasi, Cambridge, MA US

Patent application numberDescriptionPublished
20090197856ANTIVIRAL COMPOUNDS - Provided are compounds of Formula (I) or a pharmaceutically acceptable salt or solvate thereof. The compounds and compositions are useful for treating viral infections caused by the Flaviviridae family of viruses.08-06-2009

Ruben Alberto Tommasi, Cambridge, MA US

Patent application numberDescriptionPublished
20110014186ARYLSULFONAMIDE-BASED MATRIX METALLOPROTEASE INHIBITORS - The present invention provides a compound of formula (I):01-20-2011
20110112076SELECTIVE HYDROXAMIC ACID BASED MMP-12 AND MMP-13 INHIBITORS - The present invention provides a compound of formula (I) said compound is inhibitor of MMP-12 and/or MMP-13, and thus can be employed for the treatment of a disorder or disease characterized by abnormal activity of MMP-12 and/or MMP-13. Accordingly, the compound of formula (I) can be used in treatment of disorders or diseases mediated by MMP-12 and/or MMP-13. Finally, the present invention also provides pharmaceutical composition that include the compound of formula (I).05-12-2011

Ruben Alberto Tommasi, Stow, MA US

Patent application numberDescriptionPublished
20090318511SELECTIVE HYDROXAMATE BASED MMP INHIBITORS - The present invention provides a compound of formula (I):12-24-2009

Stella Tommasi, South Pasadena, CA US

Patent application numberDescriptionPublished
20100267809DOUBLE STRANDED NUCLEIC ACID TARGETING LOW COPY PROMOTER-SPECIFIC RNA - The present invention relates to transcriptional gene silencing (TGS) in mammalian, including human, cells that is mediated by small interfering RNA (siRNA) molecules. The present invention also relates to a double stranded nucleic acid that directs methylation of histones associated with target genes that produce low copy promoter-specific RNA. It has been found that siRNAs can be used to direct methylation of histones in mammalian, including human, cells.10-21-2010