Patent application number | Description | Published |
20080241351 | USING MAGNETISM TO PREPARE A MEDICAL DEVICE - The present invention is directed to methods, processes, and systems for delivering therapeutic agent to a medical device. Under some methods, processes, and systems of the invention, particles including a magnetic material and a therapeutic agent may be directed towards a medical device via magnetic attraction. In another embodiment particles including a magnetic material may force a therapeutic agent/solvent solution into porous matrix by using a magnetic attraction. In still another embodiment, a medical device having at least a portion thereof including a magnetic material is used to attract and adhere particles comprising magnetic material and therapeutic agent to a target surface of the medical device, wherein the particles are fused to the target surface. | 10-02-2008 |
20090048666 | Medical devices having porous carbon adhesion layers - According to an aspect of the present invention, medical devices are provided which comprise a substrate, a porous carbon layer disposed on at least a portion of the substrate surface, and a polymeric layer disposed on at least a portion of the porous carbon layer. | 02-19-2009 |
20090061071 | Porous medical articles for therapeutic agent delivery - According to an aspect of the present invention a method is provided which a porous medical article is contacted with a solution that contains a therapeutic agent and a solvent in order to load the pores of the medical article, after which the solvent is sublimated. | 03-05-2009 |
20090081271 | MEDICAL DEVICES HAVING A FILTER INSERT FOR CONTROLLED DIFFUSION - An implantable or insertable medical device is provided which includes as components: (a) a substrate component comprising a depression that is at least partially filled with a therapeutic agent-containing material that comprises a first therapeutic agent, and (b) a pre-formed filter insert disposed in the depression such that it regulates transport of chemical species between the depression and the exterior of the device upon implantation or insertion of the device in vivo. | 03-26-2009 |
20090081272 | MEDICAL DEVICES HAVING A METAL PARTICULATE COMPOSITION FOR CONTROLLED DIFFUSION - An implantable or insertable medical device is provided which includes as components: (a) a substrate component comprising a depression that is at least partially filled with a therapeutic agent-containing material that comprises a first therapeutic agent, and (b) a particulate composition disposed in the depression such that it regulates transport of chemical species between the depression and the exterior of the device upon implantation or insertion of the device into a subject. | 03-26-2009 |
20090123521 | Medical devices having coatings for controlled therapeutic agent delivery - According to an aspect of the invention, medical devices are provided, which include a nanoparticle-derived inorganic layer disposed over a least a portion of structure that includes a substrate, and optionally, a therapeutic-agent-containing layer disposed over at least a portion of the substrate. In some embodiments, the inorganic layer is a nanoporous inorganic layer. Other aspects of the invention comprise methods for forming such medical device. | 05-14-2009 |
20090264975 | MEDICAL DEVICES HAVING A COATING OF INORGANIC MATERIAL - In one aspect, a medical device has a first configuration and a second configuration, a reservoir containing a therapeutic agent, and a barrier layer disposed over the reservoir, wherein the barrier layer comprises an inorganic material. In another aspect, a medical device has a reservoir containing a therapeutic agent, a barrier layer disposed over the reservoir, wherein the barrier layer comprises an inorganic material, and a swellable material disposed between the barrier layer and a surface of the medical device, wherein the swellable material is a material that swells upon exposure to an aqueous environment. In yet another aspect, a medical device has a multi-layered coating having alternating reservoir layers and barrier layers, and a plurality of excavated regions penetrating through at least a partial thickness of the multi-layered coating. In yet another aspect, a medical device has a polymer layer comprising a block co-polymer, wherein the polymer layer contains a therapeutic agent, and a barrier layer disposed over the polymer layer, wherein the barrier layer comprises an inorganic material, and wherein the barrier layer has a plurality of discontinuities. Methods of forming coatings on medical devices and methods of delivering therapeutic agents to body sites are also disclosed. | 10-22-2009 |
20110130829 | Medical Devices Containing Therapeutic Agents - The present invention pertains to implantable or insertable medical devices which comprise a substrate and one or more therapeutic-agent-containing regions contain one or more therapeutic agents. In various aspects of the invention, one or more characteristics of such therapeutic-agent-containing regions are controlled. Further aspects of the invention relate to methods of forming such devices and to methods of using such devices. | 06-02-2011 |
Patent application number | Description | Published |
20080241218 | Coated medical devices for abluminal drug delivery - The invention relates generally to an implantable medical device for delivering a therapeutic agent to the body tissue of a patient, and a method for making such a medical device. In particular, the invention pertains to an implantable stent, such as an intravascular stent, having a coating comprising an inorganic or ceramic oxide, metal or inert carbon and a plurality of reservoirs in such material that contain a therapeutic agent. | 10-02-2008 |
20080243231 | Medical device with a porous surface for delivery of a therapeutic agent - The present invention is generally directed to implantable medical devices for delivering therapeutic agents to the body tissue of a patient and methods for making such medical devices. In particular, the present invention is directed to implantable medical devices, such as intravascular stents, having a surface that includes a plurality of cavities and a plurality of pores and a composition disposed in the pores and/or cavities, as well as, implantable medical devices, such as intravascular stents, having a surface that has a coating composition disposed on the surface, wherein the coating composition includes a plurality of cavities and a plurality of pores and another coating composition disposed in the pores and/or cavities. | 10-02-2008 |
20080281409 | STENTS WITH DRUG ELUTING COATINGS - Provided is a coated medical device (e.g., a stent) comprising one or more surfaces having dispersed thereon a plurality of microparticles comprising an active pharmaceutical ingredient (API) and a polymer. Specifically, the microparticles are disposed on a device surface in a microparticulate phase coating, i.e., as discrete microparticles in the absence of a continuous phase coating. The medical device effectively adheres one or more APIs to its surface, and allows controlled release of the APIs from the device surface to a desired treatment area by using a minimal amount of polymer. The medical device is suitable for insertion or implantation into a subject, preferably a human. Also provided are methods for preparing and using the coated medical device. | 11-13-2008 |
20120095396 | Drug Eluting Medical Device Utilizing Bioadhesives - A medical balloon having an inner surface and an outer surface comprising a first coating composition comprising at least one therapeutic agent, the first coating composition disposed on the balloon outer surface and forming an interface between the balloon outer surface and the first coating composition and a second coating composition comprising a bioadhesive, the second coating composition disposed on the first coating composition so as to not affect the interface between the balloon outer surface and the first coating composition, the bioadhesive selected so as to adhere to body tissue, and methods of making the same. | 04-19-2012 |
20130066257 | Design of Interventional Cutting Balloon with Enhanced API Delivery Capability - A medical balloon assembly including an inflatable balloon and at least one cutting element extending from the balloon is disclosed. The inflatable balloon includes an outer wall facing outward and an inner wall facing outward. The cutting element comprises a plurality of openings therein including a first opening and a second opening. The first opening is closed off by a portion of the outer wall. The cutting element further includes a passageway extending from the first opening to the second opening. The passageway is defined by the cutting element and the portion of the outer wall which closes off the passageway. The passageway may contain a therapeutic agent. | 03-14-2013 |
Patent application number | Description | Published |
20130280691 | WRITE ERASABLE COMPONENT SYSTEM - A series of devices that allow for embedding of an image as a background while also affording the user the ability to write and print on the surface, with erasable capabilities, thus providing a multifunctional product for use in numerous industries. The devices are manufactured from predominately corrugated plastic. In one embodiment, a writable board, or peg board comprising a front panel and a rear panel wherein the panels are interconnected by parallel rows, or corrugations, these panels include a writable and erasable surface. The present invention relates to novel assemblies of conventional corrugated plastic sheets to better serve personal, business, and educational needs. | 10-24-2013 |
20150056599 | WRITE ERASABLE COMPONENT SYSTEM - A series of devices that allow for embedding of an image as a background while also affording the user the ability to write and print on the surface, with erasable capabilities, thus providing a multifunctional product for use in numerous industries. The devices are manufactured from predominately corrugated plastic. In one embodiment a one piece, removably attachable, cabinet system and graphic display system. In an additional embodiment, a writable board, or peg board comprising a front panel and a rear panel wherein the panels are interconnected by parallel rows, or corrugations, these panels include a writable and erasable surface. The present invention relates to assemblies of corrugated systems to better serve personal, business, and educational needs. | 02-26-2015 |