Patent application number | Description | Published |
20090117074 | Sulfonylpyrroles as Histone Deacetylase Inhibitors - The invention relates to compounds of formula (I) | 05-07-2009 |
20090156604 | FUSED BICYCLIC IMIDAZOLES - Compounds of formula (I) | 06-18-2009 |
20090263353 | Novel Sulphonylpyrroles as Inhibitors of Hdac S Novel Sulphonylpyrroles - Compounds of a certain formula I, | 10-22-2009 |
20090297473 | Sulphonylpyrrole Hydrochloride Salts as Histone Deacetylases Inhibitors - Compounds of a certain formula 1, | 12-03-2009 |
20100074862 | N-SULPHONYLPYRROLES AND THEIR USE AS HISTONE DEACETYLASE INHIBITORS - Compounds of a certain formula (I), in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors. | 03-25-2010 |
20100104659 | BENZOPYRANOPYRAZOLES - Compounds of a certain formula I, in which Ra, Rb and Rc have the meanings indicated in the description, are effective compounds with anti-proliferative and/or apoptosis inducing activity. | 04-29-2010 |
20100278833 | THIOPHENE-IMIDAZOPYRIDINES - The invention relates to thiophene-imidazopyridine compounds according to formula (I), wherein the substituents and symbols are as defined in the description. The compounds are inhibitors of PIk1. | 11-04-2010 |
20110021494 | NOVEL TETRAHYDRO-FUSED PYRIDINES AS HISTONE DEACETYLASE INHIBITORS - The compounds of formula (I), wherein ring D and ring E together form a fused ring system selected from formula (II), (III), (IV), (V), (VI), (VII), and the salts of these compounds are novel, effective inhibitors of histone deacetylases. | 01-27-2011 |
20110065734 | NOVEL BIFUNCTIONAL COMPOUNDS WHICH INHIBIT PROTEIN KINASES AND HISTONE DEACETYLASES - The present invention relates to a bifunctional compound of formula I or its pharmaceutically acceptable salts or solvates A-L-B (I) wherein A is a histone deacetylase (HDAC) inhibitory moiety, L is a single bond or a linker group and B is a protein kinase inhibitory moiety. The bifunctional compound according to formula (I) is useful for the treatment of malignant and non-malignant neoplasia and diseases related to abnormal cell growth. | 03-17-2011 |
20110086897 | (E)-N-(2-Amino-phenyl)-3--acrylamide salts - A salt of (E)-N-{2-amino-phenyl)-3-{1-[4-(1-methyl-1H-pyrazol-4-yl)-beπzenesulfonyl]-1H-pyrrol-3-yl)-acrylamide selected from the group consisting of the hydrobromide, methansulfonate, hemi ethane-1,2-disulfonate, benzenesulfonate, toiuenesulfonate and 2-naphthalenesulfonate. | 04-14-2011 |
20110105568 | NOVEL METHOD FOR THE PRODUCTION OF SULPHONYLPYRROLES AS HDAC INHIBITORS - Process for the preparation of a compound of formula (I) wherein R1, R2, R3, R4, R5 and R6 have the meanings as defined in the specification, comprising the step of reacting an acrylic acid chloride compound of formula (II′): wherein R1, R2, R3, R4, R5 and R6 have the meanings as defined in the specification, with aqueous hydroxylamine and optionally converting the resulting compound into an acid addition salt thereof. | 05-05-2011 |
20110201643 | NOVEL N-SUBSTITUTED TETRAHYDROISOQUINOLINE/ISOINDOLINE HYDROXAMIC ACID COMPOUNDS - Compounds of a certain formula (I) wherein R1, R2, R3, X, Y, r, s, t, u and v have the meanings as defined in the specification, and the salts, solvates and hydrates thereof are novel effective HDAC 6 inhibitors. | 08-18-2011 |
20110245289 | NOVEL SUBSTITUTED IMIDAZOQUINOLINES - Imidazoquinolines of formula I that contain substituted amine or amide functionality at 1-position and that are effective as Toll like Receptor 7 activators are disclosed. These compounds are useful as anticancer agents. | 10-06-2011 |
20120289474 | 3,4,4A,10B-TETRAHYDRO-1H-THIOPYRANO-[4,3-c] ISOQUINOLINE DERIVATIVES - The compounds of Formula (1), | 11-15-2012 |
20130310362 | FUSED PYRIMIDINES - The present invention relates to compounds of formula (I), | 11-21-2013 |
20130317002 | FUSED PYRIMIDINES - Compounds of formula (I) | 11-28-2013 |
20140088110 | FUSED BICYCLIC IMIDAZOLES - Compounds of formula (I) | 03-27-2014 |
20140112945 | NOVEL PHTHALAZINONE-PYRROLOPYRIMIDINECARBOXAMIDE DERIVATIVES - The compounds of formula (1) | 04-24-2014 |