Inventors list |
Assignees list |
Classification tree browser |
Top 100 Inventors |
Top 100 Assignees |
Thomas E. Wagner
Thomas E. Wagner, Greenville, SC US
| Patent application number | Description | Published |
|---|---|---|
| 20080242610 | POLYPEPTIDES COMPRISING FAS ACTIVATION AND NKG2D-LIGAND DOMAINS - The present invention is drawn to fusion proteins comprising (a) a ligand for an NK receptor and (b) a Fas activation domain, and to nucleic acids encoding such fusion proteins. The invention also includes methods of making and using such proteins and nucleic acids, including their use in preventing or treating cancer. | 10-02-2008 |
| 20090081789 | Activation of nuclear factor kappa B - The present invention describes a method for targeting a tumor cell comprising contacting the tumor cell with a composition comprising a macrophage and a factor that upregulates nuclear factor-kappa B (NFκB) activity. | 03-26-2009 |
| 20090117658 | Macrophage transfection method - Described are a method and a composition for transfecting monocytes, as well as use of the same for therapeutic purposes. The composition is composed of a nucleic acid component, a lysosome evading component and a digestible particle that can be phagocytized. Preferably, the monocyte is a macrophage and the digestible particle is from a natural source, such as from a microbial source. More preferably, the digestible particle is a yeast cell wall particle such as zymosan. The composition itself, or cells pretreated with the composition, are useful in all gene medicine applications, such as gene therapy, gene vaccination, cancer treatment as well as immunomodulation and tissue repair. | 05-07-2009 |
| 20100111985 | VACCINE COMPOSITIONS AND METHODS OF USE - Described are a method and a composition for delivery of a protein to an antigen presenting cell. The composition is composed of a polypeptide component, a buffering component and a particle to be phagocytized. In one embodiment, the antigen presenting cell is aa macrophage or a dendritic cell and the particle to be phagocytized is from a natural source, such as from a microbial source. The composition itself, or cells pretreated with the composition, are useful for strategies in vaccine development. | 05-06-2010 |
| 20100284975 | POLYPEPTIDES COMPRISING FAS ACTIVATION AND NKG2D-LIGAND DOMAINS - The present invention is drawn to fusion proteins comprising (a) a ligand for an NK receptor and (b) a Fas activation domain, and to nucleic acids encoding such fusion proteins. The invention also includes methods of making and using such proteins and nucleic acids, including their use in preventing or treating cancer. | 11-11-2010 |
Thomas E. Wagner, Greer, SC US
| Patent application number | Description | Published |
|---|---|---|
| 20080213923 | DNA-Based Memory Device and Method of Reading and Writing Same - The present invention is directed to a memory device having very high storage density capability. In general, the memory device includes an array of individual memory cells which store information that is assigned a value based on the molecular contents of the memory cell. In a preferred embodiment, the molecules utilized for storing information in the memory cells may be single-strand polynucleotides, for instance single-strand oligonucleotides of between about 5 and about 20 monomer units. The present invention is also directed to methods and systems useful for writing and reading the molecular-based memory devices. In particular, the devices may be written and read via modified atomic force microscopy processes. | 09-04-2008 |
| 20090087450 | Combination therapy of hybrid cells with BCG injection for treating Cancer Patients - The present invention relates to cancer treatment compositions and methods for a specific cancer patient population. In particular, the application describes methods of treating a patient with cancer, such as a neuroblastoma, with a hybrid cell preparation in combination with | 04-02-2009 |
| 20100047288 | Hybrid cells for treating cancer patients - The present invention relates to cancer treatment compositions and methods for treating a specific cancer patient population. In particular, the application describes methods of treating a patient with cancer, such as a neuroblastoma, with a hybrid cell preparation. | 02-25-2010 |
Thomas E. Wagner, Fenton, MO US
| Patent application number | Description | Published |
|---|---|---|
| 20090001151 | Boat motor, submarine, and other structures mailbox design - A boat motor mailbox, or one that may be structured as a submarine, airplane, locomotive engine, steamboat, or one in which its address illuminated, incorporating a upper container, an integral shaft or other supporting housing, to provide for operativness or illumination of the numbers upon the formed mailbox. In the instance of a boat motor, it may include a motor operative propeller, which may also provide for similar operation to a submarine, steamboat, an airplane, or other configured shapes that are embodied into the structure of the mailbox design. The operating mechanism may receive its electrical energy from solar power, a battery pack, or even hardwired, and which sustains, in the case of the battery, recharging through the use of the solar collecting panel. In the case of the boat motor, it may have an attached spike, at its bottom, that allows for the mail box to be attached into the ground, whether the spike be impaled within the mud, or be cemented by concrete into the ground, for more permanent usage. | 01-01-2009 |
Thomas E. Wagner, Grand Rapids, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20120055123 | CORNER POST APPLICATION SYSTEM - A corner post application system comprises a conveyor subsystem and an enveloping machine adapted to envelope the plurality of units with a material. The system further includes a swing arm, an applicator arm coupled to the swing arm and adapted to move linearly, a corner post gripper coupled to the applicator arm, and a controller. The controller rotates the swing arm about a vertical axis until a corner post held by the corner post gripper is aligned with adjacent sides that define a corner of the load. The controller thereafter stops rotation of the swing arm and moves the applicator arm linearly toward the corner of the load until the corner post held by the corner post gripper contacts the adjacent sides of the load. A sensor may be included for detecting a corner of the load, with the controller aligning the corner post based on detection by the sensor. | 03-08-2012 |