Patent application number | Description | Published |
20100134759 | DIGITAL IMAGING SYSTEM FOR EYE PROCEDURES - Described herein is a hand-held gonioscopic imaging system that can be used to continuously display, capture and record images of the iridocorneal angle within the eye during implantation procedures. The system can be used, for example, during device implantation procedures for the treatment of glaucoma such that landmark identification continues during implantation. Intuitive real-time images viewed through the imaging systems described herein appear to the user to move in the same horizontal orientation as the instrument is actually being moved. The systems described herein also provide independent illumination sources for the camera and the surgical microscope that also have independent illumination controls. | 06-03-2010 |
20100137981 | OCULAR IMPLANT WITH SHAPE CHANGE CAPABILITIES - Disclosed are devices, methods and systems for treatment of eye disease such as glaucoma. Implants are described herein that enhance aqueous flow through the normal outflow system of the eye with minimal to no complications. The implant can be reversibly deformed to a first shape, such as a generally linear shape conducive to insertion. Upon insertion, the implant can deform to a second shape, such as a generally non-linear shape conducive to retention within the eye. The shape also improves fluid flow from the anterior chamber and prevents or reduces clogging. | 06-03-2010 |
20100274258 | OCULAR IMPLANT WITH STIFFNESS QUALITIES, METHODS OF IMPLANTATION AND SYSTEM - Described herein are devices and methods for treating eye conditions. Described is an ocular implant including an elongate member having an internal lumen forming a flow pathway, at least one inflow port communicating with the flow pathway, and at least one outflow port communicating with the flow pathway. The elongate member is adapted to be positioned in the eye such that at least one inflow port communicates with the anterior chamber, at least one outflow port communicates with the suprachoroidal space to provide a fluid pathway between the anterior chamber and the suprachoroidal space when the elongate member is implanted in the eye. The elongate member has a wall material imparting a stiffness to the elongate member. The stiffness is selected such that after implantation the elongate member deforms eye tissue surrounding the suprachoroidal space forming a tented volume. | 10-28-2010 |
20100280317 | OCULAR IMPLANT DELIVERY SYSTEMS AND METHODS - Described herein are delivery devices and methods of using the devices for delivering an ocular implant into a suprachoroidal space without use of a goniolens. The delivery device includes a handle including a channel extending from a proximal end of the handle to a distal end of the handle, an applier coupled to the handle, the applier including a blunt distal tip and an elongate, flexible wire insertable through a fluid channel of an ocular implant, and a fiber optic image bundle reversibly inserted through the channel such that the fiber optic image bundle extends to a region proximal to the blunt distal tip of the applier. | 11-04-2010 |
20110028983 | OCULAR IMPLANT WITH STIFFNESS QUALITIES, METHODS OF IMPLANTATION AND SYSTEM - Described herein are devices and methods for treating eye conditions. Described is an ocular implant including an elongate member having an internal lumen forming a flow pathway, at least one inflow port communicating with the flow pathway, and at least one outflow port communicating with the flow pathway. The elongate member is adapted to be positioned in the eye such that at least one inflow port communicates with the anterior chamber, at least one outflow port communicates with the suprachoroidal space to provide a fluid pathway between the anterior chamber and the suprachoroidal space when the elongate member is implanted in the eye. The elongate member has a wall material imparting a stiffness to the elongate member. The stiffness is selected such that after implantation the elongate member deforms eye tissue surrounding the suprachoroidal space forming a tented volume. | 02-03-2011 |
20110087148 | OCULAR IMPLANT WITH STIFFNESS QUALITIES, METHODS OF IMPLANTATION AND SYSTEM - Described herein are devices and methods for treating eye conditions. Described is an ocular implant including an elongate member having an internal lumen forming a flow pathway, at least one inflow port communicating with the flow pathway, and at least one outflow port communicating with the flow pathway. The elongate member is adapted to be positioned in the eye such that at least one inflow port communicates with the anterior chamber, at least one outflow port communicates with the suprachoroidal space to provide a fluid pathway between the anterior chamber and the suprachoroidal space when the elongate member is implanted in the eye. The elongate member has a wall material imparting a stiffness to the elongate member. The stiffness is selected such that after implantation the elongate member deforms eye tissue surrounding the suprachoroidal space forming a tented volume. | 04-14-2011 |
20110105990 | ZONAL DRUG DELIVERY DEVICE AND METHOD - Disclosed herein are ocular implants for treating an eye and methods of implantation including an elongate member having a proximal end with at least one inflow port, a distal end with at least one outflow port, and a longitudinal, internal lumen extending through the elongate member. The distal end of the elongate member is in fluid communication with the suprachoroidal space such that the proximal end of the elongate member remains in fluid communication with the anterior chamber when the elongate member is implanted in the eye. At least one polymeric film surrounds at least a portion of the elongate member, the film comprising a first drug delivery zone embedded with a first drug, wherein the first drug diffuses from the polymeric film over time into the eye at a first anatomical location. | 05-05-2011 |
20110112546 | OCULAR IMPLANT APPLIER AND METHODS OF USE - Described herein is a delivery device and methods for delivering an ocular implant into an eye. The delivery device includes a proximal handle portion; a distal delivery portion coupled to a distal end of the handle portion and configured to releasably hold an ocular implant and includes a sheath positioned axially over a guidewire; and a metering system configured to provide visual guidance regarding depth of advancement of an implant positioned on the guidewire into an anatomic region of the eye. Also disclosed is a device and method for loading an implant onto the delivery device. | 05-12-2011 |
20110118835 | BRANCHED OCULAR IMPLANT - Disclosed is a glaucoma treatment device having a tubular, unbranched portion and a branched portion. The unbranched portion has an internal flow pathway extending between a distal region and a proximal region. The branched portion extends from the distal region of the tubular, unbranched portion. The proximal region of the unbranched portion includes at least one inflow port that is in fluid communication with the internal flow pathway. The branched portion includes a first and a second reversibly deformable branch. Each of the first and second branches has at least one outflow port and an internal lumen in fluid communication with the flow pathway of the unbranched portion. Each of the first and second branches is biased away from one another when in a relaxed state. | 05-19-2011 |
20110238075 | DRUG DELIVERY DEVICES AND METHODS - This disclosure relates generally to methods and devices for use in treating eye conditions with implantable drug delivery devices. One method includes introducing an implant into the suprachoroidal space, wherein the interior volume of the implant is plugged with a drug-release material comprising at least one active agent that elutes through at least one opening in the implant, wherein the drug-release material degrades from the interior volume of the implant over a period time. | 09-29-2011 |
20110238173 | OPHTHALMIC DEVICES HAVING A DEGRADATION RESISTANT POLYMER - Disclosed are ophthalmic devices configured to be implanted in an eye of a patient. In one embodiment, the ophthalmic device includes a mask configured to increase the depth of focus of the patient and comprising a highly fluorinated polymeric material in which the number of carbon-fluorine bonds equals or exceeds the number of carbon-hydrogen bonds in the highly fluorinated polymeric material. The highly fluorinated polymeric material can be resistant to degradation upon exposure to ultraviolet light. The mask further includes an aperture configured to transmit light and a portion configured to be substantially opaque to visible light and to surround at least a portion of the aperture. | 09-29-2011 |
20120016286 | OCULAR IMPLANT WITH STIFFNESS QUALITIES, METHODS OF IMPLANTATION AND SYSTEM - Described herein are devices and methods for treating eye conditions. Described is an ocular implant including an elongate member having an internal lumen forming a flow pathway, at least one inflow port communicating with the flow pathway, and at least one outflow port communicating with the flow pathway. The elongate member is adapted to be positioned in the eye such that at least one inflow port communicates with the anterior chamber, at least one outflow port communicates with the suprachoroidal space to provide a fluid pathway between the anterior chamber and the suprachoroidal space when the elongate member is implanted in the eye. The elongate member has a wall material imparting a stiffness to the elongate member. The stiffness is selected such that after implantation the elongate member deforms eye tissue surrounding the suprachoroidal space forming a tented volume. | 01-19-2012 |
20120022429 | OCULAR IMPLANT WITH STIFFNESS QUALITIES, METHODS OF IMPLANTATION AND SYSTEM - Described herein are devices and methods for treating eye conditions. Described is an ocular implant including an elongate member having an internal lumen forming a flow pathway, at least one inflow port communicating with the flow pathway, and at least one outflow port communicating with the flow pathway. The elongate member is adapted to be positioned in the eye such that at least one inflow port communicates with the anterior chamber, at least one outflow port communicates with the suprachoroidal space to provide a fluid pathway between the anterior chamber and the suprachoroidal space when the elongate member is implanted in the eye. The elongate member has a wall material imparting a stiffness to the elongate member. The stiffness is selected such that after implantation the elongate member deforms eye tissue surrounding the suprachoroidal space forming a tented volume. | 01-26-2012 |
20120035524 | EXPANDABLE OCULAR DEVICES - Disclosed herein are systems, devices and methods for treating an ocular disorder in an eye. The ocular device includes a proximal end, a distal end, and an internal lumen forming a flow pathway extending from the proximal end to the distal end; at least one inflow region that communicates with the flow pathway; and an expandable portion having a plurality of interconnected struts forming multiple openings in the device communicating with the flow pathway. The expandable portion has a first cross-sectional shape suitable for insertion into the eye that is generally cylindrical and a second cross-sectional shape that is larger than the first cross-sectional shape. The system also includes a delivery device for inserting the ocular device into an eye including a sheath configured to surround at least a portion of the ocular device; an applier configured to insert into the internal lumen of the ocular device; and an actuator. | 02-09-2012 |
20120035525 | OCULAR IMPLANT WITH FLUID OUTFLOW PATHWAYS HAVING MICROPOROUS MEMBRANES - Disclosed are devices, methods and systems for treatment of eye disease such as glaucoma. Implants are described herein that enhance aqueous flow through the normal outflow system of the eye with minimal to no complications. The implant can include reversibly deformable portions that have a plurality of openings layered, covered or otherwise spanned by an elastomeric film or membrane having micropores. The micropores allow for fluid flow out of the implant while inhibit cellular infiltration and blockage of the openings. | 02-09-2012 |
20120310137 | EYE SHUNT WITH POROUS STRUCTURE - Disclosed are devices and methods for treatment of eye disease such as glaucoma. An implant is placed in the eye wherein the implant provides a fluid pathway for the flow or drainage of aqueous humor from the anterior chamber to the supraciliary or the suprachoroidal space, or to any space in the eye where drainage to that location will lower the intraocular pressure. The implant may include an elongate compressible structure and may be implanted in the eye using a delivery system that folds and or compresses the implant to provide a smaller cross-sectional area to allow a more minimally-invasive procedure. The compressibility of the implant is provided by a porous structure that may be collapsed by compression and delivered through a tube-shaped introducer. | 12-06-2012 |
20130053953 | OPHTHALMIC DEVICES HAVING A DEGRADATION RESISTANT POLYMER - Disclosed are ophthalmic devices configured to be implanted in an eye of a patient. In one embodiment, the ophthalmic device includes a mask configured to increase the depth of focus of the patient and comprising a highly fluorinated polymeric material in which the number of carbon-fluorine bonds equals or exceeds the number of carbon-hydrogen bonds in the highly fluorinated polymeric material. The highly fluorinated polymeric material can be resistant to degradation upon exposure to ultraviolet light. The mask further includes an aperture configured to transmit light and a portion configured to be substantially opaque to visible light and to surround at least a portion of the aperture. | 02-28-2013 |
20130110125 | Ocular Implant Delivery Systems And Methods | 05-02-2013 |
20140066831 | OCULAR IMPLANT WITH STIFFNESS QUALITIES, METHODS OF IMPLANTATION AND SYSTEM - Described herein are devices and methods for treating eye conditions. Described is an ocular implant including an elongate member having an internal lumen forming a flow pathway, at least one inflow port communicating with the flow pathway, and at least one outflow port communicating with the flow pathway. The elongate member is adapted to be positioned in the eye such that at least one inflow port communicates with the anterior chamber, at least one outflow port communicates with the suprachoroidal space to provide a fluid pathway between the anterior chamber and the suprachoroidal space when the elongate member is implanted in the eye. The elongate member has a wall material imparting a stiffness to the elongate member. The stiffness is selected such that after implantation the elongate member deforms eye tissue surrounding the suprachoroidal space forming a tented volume. | 03-06-2014 |
20140107556 | OCULAR IMPLANT WITH SHAPE CHANGE CAPABILITIES - Disclosed are devices, methods and systems for treatment of eye disease such as glaucoma. Implants are described herein that enhance aqueous flow through the normal outflow system of the eye with minimal to no complications. The implant can be reversibly deformed to a first shape, such as a generally linear shape conducive to insertion. Upon insertion, the implant can deform to a second shape, such as a generally non-linear shape conducive to retention within the eye. The shape also improves fluid flow from the anterior chamber and prevents or reduces clogging. | 04-17-2014 |
20140142378 | OCULAR IMPLANT DELIVERY SYSTEMS AND METHODS - Described herein are delivery devices and methods of using the devices for delivering an ocular implant into a suprachoroidal space without use of a goniolens. The delivery device includes a handle including a channel extending from a proximal end of the handle to a distal end of the handle, an applier coupled to the handle, the applier including a blunt distal tip and an elongate, flexible wire insertable through a fluid channel of an ocular implant, and a fiber optic image bundle reversibly inserted through the channel such that the fiber optic image bundle extends to a region proximal to the blunt distal tip of the applier. | 05-22-2014 |
20140171885 | DRUG DELIVERY DEVICES AND METHODS - This disclosure relates generally to methods and devices for use in treating eye conditions with implantable drug delivery devices. One method includes introducing an implant into the suprachoroidal space, wherein the interior volume of the implant is plugged with a drug-release material comprising at least one active agent that elutes through at least one opening in the implant, wherein the drug-release material degrades from the interior volume of the implant over a period time. | 06-19-2014 |
20140277432 | IN SITU ADJUSTABLE OPTICAL MASK - Implantable corneal and intraocular implants such as a mask are provided. The mask can improve the vision of a patient, such as by being configured to increase the depth of focus of an eye of a patient. The mask can include an aperture configured to transmit along an optical axis substantially all visible incident light. The mask can further include a transition portion that surrounds at least a portion of the aperture. This portion can be configured to switch from one level of opacity to another level of opacity through the use of a controllably variable absorbance feature such as a switchable photochromic chromophore within a polymer matrix. | 09-18-2014 |