Patent application number | Description | Published |
20100046821 | MOTION CORRECTION IN TOMOGRAPHIC IMAGES - An imaging method comprises reconstructing gated emission tomography images for a region of interest, adjusting a mismatch between the gated emission tomography images and a computed tomography image of the region of interest, registering the gated emission tomography images, and combining the registered gated emission tomography images to generate motion corrected images. | 02-25-2010 |
20100189324 | METHOD AND APPARATUS FOR REDUCING IMAGE ARTIFACTS - A method and apparatus are provided for reducing motion related imaging artifacts. The method includes obtaining an image data set of a region of interest in an object, obtaining a motion signal indicative of motion of the region of interest, and determining a displacement and a phase of at least a portion of the motion signal. The method also includes mapping the image data set into a matrix based on the displacement and phase of the motion signal, and generating an image of the region of interest from the matrix. | 07-29-2010 |
20100220909 | METHOD AND APPARATUS FOR REDUCING IMAGE ARTIFACTS - A method and apparatus are provided for reducing motion related imaging artifacts. The method includes determining an internal motion for of two regions of the object, each region having a different level of motion, scanning the first region using a first scan protocol based on the motion, scanning a second region using a second different scan protocol based on the motion, and generating an image of the object based on the first and second regions. | 09-02-2010 |
20110116695 | METHOD AND APPARATUS FOR REDUCING MOTION-RELATED IMAGING ARTIFACTS - A method and apparatus are provided for reducing motion related imaging artifacts. The method includes obtaining an image data set of a region of interest in an object, obtaining a motion signal indicative of motion of the region of interest, determining at least one quiescent period of at least a portion of the motion signal, extracting image data from the image data set that is within the determined quiescent period to form an image data subset, and generating an image of the region of interest using the image data subset. | 05-19-2011 |
20120281897 | METHOD AND APPARATUS FOR MOTION CORRECTING MEDICAL IMAGES - A method for reducing, in an image, motion related imaging artifacts includes obtaining an image dataset of a region of interest, generating a plurality of intermediate images using the image dataset, applying a multivariate data analysis technique to the plurality of the intermediate images to generate motion information, sorting the intermediate images into a plurality of bins based on the motion information, and generating an image of the region of interest using at least one of the plurality of bins. | 11-08-2012 |
Patent application number | Description | Published |
20080224050 | Method of and Software for Calculating a Scatter Estimate for Tomographic Scanning and System for Tomographic Scanning - The method calculates a scatter estimate for annihilation photons in a subject having a distribution of attenuation. The method can be used for scatter correction of detection data from a positron emission tomographic scanner. The method uses the following steps: —select a first scatter point S | 09-18-2008 |
20090154641 | Method of and software for Conducting Motion Correction in Tomographic Scanning and System for Tomographic Scanning Using The Method - During data acquisition in a tomographic scan of a subject unscattered events and scatter events are collected. The data are corrected for the scatter events and movement of the subject during the scan. A scatter estimate is derived for use in the reconstruction of an image of the subject; a first step in the derivation has a first dependence on the movement of the subject. The image of the subject is derived from the detected events using the scatter estimate; a second step in this derivation has a second dependence on the movement of the subject, the dependence being different from that of the first step. | 06-18-2009 |
20100086101 | METHOD OF AND SOFTWARE FOR CALCULATING A SCATTER ESTIMATE FOR TOMOGRAPHIC SCANNING AND SYSTEM FOR TOMOGRAPHIC SCANNING - The method calculates a scatter estimate for scatter correction of detection data from a subject in a positron emission tomographic scanner. The detection data represent the scattered events and unscattered events of annihilation photons emitted in the subject. The method uses the following steps:
| 04-08-2010 |
20120305780 | METHOD AND SYSTEM FOR PROCESSING GATED IMAGE DATA - A method for generating an image is provided. The method comprises: acquiring a first set of image data using a first imaging modality; sorting the first set of image data into a plurality of gates to generate a plurality of gated data sets; reconstructing each gated data set to generate a respective gated image for each gated data set; registering the respective gated images to generate a plurality of registered images; and generating a median image from the plurality of registered images, wherein each voxel of the median image is a respective median value of the corresponding voxels of the plurality of registered images. | 12-06-2012 |
20130026370 | METHODS AND SYSTEMS FOR SCATTER ESTIMATION IN POSITRON EMISSION TOMOGRAPHY - Methods and systems for multiple scatter estimation in Positron Emission Tomography (PET) are provided. One method includes determining attenuation sinograms and determining a varying convolution kernel as a function of the attenuation sinograms, wherein the kernel varies in amplitude and width over a radial length of a PET imaging system. The method also includes using the varying convolution kernel to estimate multiple PET scatter. | 01-31-2013 |
Patent application number | Description | Published |
20100215674 | ENHANCING THE T-CELLS STIMULATORY CAPACITY OF HUMAN ANTIGEN PRESENTING CELLS AND THEIR USE IN VACCINATION - With the current invention, we provide new methods of enhancing the T-cell stimulatory capacity of human dendritic cells (DCs) and their use in cancer vaccination. The method comprises the introduction of different molecular adjuvants to human DCs through transfection with at least two mRNA or DNA molecules encoding markers selected from the group of: CD40L, CD70, constitutively active TLR4 (caTLR4), IL-12p70, EL-selectin, CCR7 and/or 4-1 BBL; or in combination with inhibition of SOCS, A20, PD-L1 and/or STAT3 expression, for example through siRNA transfection. We could show a clear increase in the immunostimulatory capacity of DCs obtained in this way, enabling them to elicit an unexpectedly high T-cell immune response in vitro. Introduction of at least two of the above molecules, in combination with a tumor-specific antigen enables the DCs to elicit a significant host-mediated T-cell immune response in vivo against the tumor antigen and thus makes them very attractive in the manufacturing of anti-cancer vaccines. | 08-26-2010 |
20130108663 | ENHANCING THE T-CELL STIMULATORY CAPACITY OF HUMAN ANTIGEN PRESENTING CELLS IN VITRO AND IN VIVO AND THEIR USE IN VACCINATION | 05-02-2013 |
20140056939 | ENHANCING THE T-CELL STIMULATORY CAPACITY OF HUMAN ANTIGEN PRESENTING CELLS IN VITRO AND IN VIVO AND ITS USE IN VACCINATION - We provide new methods of in vitro or in vivo enhancing the T-cell stimulatory capacity of human DCs and the use thereof in cancer vaccination. The method includes the introduction of different molecular adjuvants to human DCs by contacting or modifying them with mRNA or DNA molecule(s) encoding CD40L, and CD70 or constitutively active TLR4 (caTLR4). | 02-27-2014 |
Patent application number | Description | Published |
20110313153 | 5-HT4 INHIBITORS FOR TREATING AIRWAY DISEASES, IN PARTICULAR ASTHMA - The invention relates generally to the treatment of diseases of the respiratory system such as asthma and chronic obstructive pulmonary disease. More particularly, the present invention relates to methods of treating and preventing asthmatic airway inflammation. The treatment involves the administration of a 5-HT4 receptor antagonist to the subject in need thereof; more in particular the administration of aroylated 4-aminomethylpiperidine derivatives as defined herein. Other aspects of the invention are directed to compositions for treating or preventing respiratory disorders, including pharmaceutical compositions. | 12-22-2011 |
20120184537 | [1,4]-BENZODIAZEPINES AS VASOPRESSIN V2 RECEPTOR ANTAGONISTS - The invention relates to a novel class of [1,4]-benzodiazepine derivatives, processes for their preparation, intermediates usable in these processes, and pharmaceutical compositions containing the compounds. Other aspects of the invention are directed to the use of said [1,4]-benzodiazepine derivatives in therapy based on the capability of said compounds to interfere with the binding of the peptide hormone, vasopressin, to its receptors. In particular as vasopressin V2 receptor antagonists and therefore useful for treating involving increased vascular resistance, cardiac insufficiency, and water retention. | 07-19-2012 |