Patent application number | Description | Published |
20100145361 | Methods and Devices for Occlusion of an Atrial Appendage - A novel occluder application and clip device for treatment of embolic stroke caused by atrial fibrillation uses multiple sutures in a non directional handle to affix the occlusion device to the applicator and manipulate the occluder from an open and receiving position to a closed and occluding position. The occluder is retained in place by a clamping means related to locks retainers, resilient material or otherwise. An actuator mechanism is used to manipulate the occluder to a locked or occluding position. The applicator with the occluder attached has a low profile and remote manipulations to allow the occluder to be delivered to the clamping location within a patient through a small incision or delivery port such as a trocar cannula or the like. | 06-10-2010 |
20130144538 | Clot Protection and Detection Algorithm for Activated Clotting Time Testing - Activated clotting time (ACT) tests detect blood clotting time based on the viscosity changes of a test sample, using a ferromagnetic washer lifted to the top of a test chamber and then dropped from the top via gravity; a drop time greater than a preset threshold value indicates clotting of the test sample. Blood samples which have high levels of heparin usually produce very weak clots that may easily be destroyed by the lifting movement of the washer. But if the clot threshold is set low to detect the weak clots, false detections occur during early testing cycles when activators are not fully suspended during the mixing cycle. Improved algorithms for lifting the washer and adjusting over time enable accurate detection of weak clots. | 06-06-2013 |
20130189789 | High Range Activated Clotting Time Assay Formulation - High range activated clotting time (HR-ACT) tests detect blood clotting time in blood samples which have high levels of heparin. Reagents such as calcium chloride and kaolin within the test apparatus trigger clotting. Physical separation of the reagents from each other prevents interaction between them before the test sample introduction. In one embodiment, to improve dry kaolin re-suspension, kaolin may be suspended in water rather than buffered saline before being dispensed into the test chamber. The combination of removing the buffered saline and the calcium chloride from the kaolin suspension enables clot detection in blood samples containing 5-6 u/ml of heparin. | 07-25-2013 |
20140273249 | High Range Activated Clotting Time Assay Formulation - High range activated clotting time (HR-ACT) tests detect blood clotting time in blood samples which have high levels of heparin. Reagents such as calcium chloride and kaolin within the test apparatus trigger clotting. The cartridge is treated with a strong surface treatment process, such as an atmospheric plasma treatment, to increase the hydrophilic property of the test chamber, there may be a significant reduction in the kaolin concentration required to activate the blood sample and initiate the coagulation process. The kaolin concentration may be further reduced if the buffer component used in the buffer saline contains phosphate. The reduction of the kaolin concentration allows more calcium to be released from the kaolin to participate in the clotting process. The combined effect of adding a surface treatment to the cartridge to increase the hydrophilic property of reaction chamber and adding phosphate into buffered saline allows for clot detection of blood samples containing 5˜6 U/mL heparin. | 09-18-2014 |
Patent application number | Description | Published |
20120000795 | NANOCOMPOSITE BASED BIOSENSORS AND RELATED METHODS - Disclosed are nanocomposite-based biosensors. The biosensors include an electrode, a nanocomposite over the surface of the electrode, the nanocomposite comprising a population of carbon nanotubes and a population of magnetic nanoparticles dispersed in the population of carbon nanotubes, wherein the magnetic nanoparticles comprise a ferromagnetic metal or compound thereof, and one or more biomolecules over the surface of the electrode, wherein the biomolecules are capable of undergoing a redox reaction with a target molecule. Also disclosed are nanocomposites, modified electrodes, kits, and methods for using the biosensors. | 01-05-2012 |
20120321542 | GRAPHENE FORMATION - Technologies are generally described for forming graphene and structures including graphene. In an example, a system effective to form graphene may include a chamber adapted to receive graphite oxide. The system may also include a source of an inert gas and a source of hydrogen, which may both be configured in communication with the chamber. A processor may be configured in communication with the chamber, the inert gas source and/or the hydrogen source. The processor may be further configured to control the flow of the inert gas from the first source through the chamber under first sufficient reaction conditions to remove at least some oxygen from the atmosphere of the chamber. The processor may also be configured to control the flow of the hydrogen from the second source to the graphite oxide in the chamber under second sufficient reaction conditions to form graphene from the graphite oxide. | 12-20-2012 |
20130224452 | METAL NANOPARTICLE-GRAPHENE COMPOSITES AND METHODS FOR THEIR PREPARATION AND USE - Methods of forming a metal nanoparticle-graphene composite are provided. The methods include providing a functionalized hydrogen exfoliated wrinkled graphene (f-HEG) substrate and dispersing metal nanoparticles on a first major surface of the f-HEG substrate to form the metal nanoparticle-graphene composite. | 08-29-2013 |
20140377790 | METAL NANOPARTICLE DECORATED CARBON NANOTUBES AND METHODS OF PREPARATION AND USE - Methods of forming metal nanoparticle decorated carbon nanotubes are provided. The methods include mixing a metal precursor with a plurality of carbon nanotubes to form a metal precursor-carbon nanotubes mixture. The methods also include exposing the metal precursor-carbon nanotubes mixture to electromagnetic radiation to deposit metal nanoparticles on a major surface of the carbon nanotubes. | 12-25-2014 |