Patent application number | Description | Published |
20110152759 | USE OF BIOMARKERS AND THERAPEUTIC AGENTS WITH SURGICAL DEVICES - Biomarkers are collected and used to determine biological propensities of a patient, to determine the efficacy of medical devices, to select and administer therapeutic agents, to select medical devices, to make adjustments to medical devices, and/or to adjust surgical techniques. An apparatus includes a port to draw a biological fluid (e.g., a mist) from a surgical site. The apparatus includes a sensor having a cantilevered beam. The beam includes substances selected to attract certain biomarkers as the fluid is communicated across the beam. The same apparatus or another apparatus is used to administer a therapeutic agent based at least in part on collected biomarker data. The therapeutic agent delivery apparatus may include a device that is also used to create a wound at a surgical site. For instance, a harmonic surgical instrument may be used to both collect biomarkers and administer a therapeutic agent (e.g., gene therapy using sonoporation). | 06-23-2011 |
20110270360 | METHODS AND DEVICES FOR ACTIVATING BROWN APIDOSE TISSUE USING ELECTRICAL ENERGY - Methods and devices are provided for activating brown adipose tissue (BAT). Generally, the methods and devices can activate BAT to increase thermogenesis, e.g., increase heat production in the patient, which over time can lead to weight loss. In one embodiment, a medical device is provided that activates BAT by electrically stimulating nerves that activate the BAT and/or electrically stimulating brown adipocytes directly, thereby increasing thermogenesis in the BAT and inducing weight loss through energy expenditure. | 11-03-2011 |
20120074200 | SURGICAL INSTRUMENT WITH SELECTIVELY ARTICULATABLE END EFFECTOR - A surgical instrument that has an articulatable end effector. The instrument includes an articulation system that has a rotatable actuator member that interfaces with an articulation transmission. Rotation of the actuator member in a first rotary direction about an actuation axis causes at least one articulation member to articulate the surgical end effector in a first articulation direction and rotation of the actuator member in a second rotary direction causes at least one articulation member to articulate the surgical end effector in a second articulation direction. | 03-29-2012 |
20120074201 | SURGICAL INSTRUMENT WITH TRIGGER ASSEMBLY FOR GENERATING MULTIPLE ACTUATION MOTIONS - A surgical instrument that has an actuation system that is configured to generate at least two separate actuation motions. A clutch assembly is movable between an engaged position wherein the clutch assembly is in operable engagement with the actuation system and an unengaged position. In various forms, the surgical instrument includes a manually actuatable trigger assembly that interfaces with the clutch assembly and the actuation system such that a first stroke of the trigger assembly causes the actuation system to generate a first one of the actuation motions and moves the clutch assembly from the unengaged position to the engaged position whereupon a second stroke of the trigger assembly causes the actuation system to generate another one of the actuation motions. | 03-29-2012 |
20120080336 | STAPLE CARTRIDGE COMPRISING STAPLES POSITIONED WITHIN A COMPRESSIBLE PORTION THEREOF - A fastener cartridge can comprise a support portion, a tissue thickness compensator positioned relative to the support portion, and a plurality of fasteners positioned within the support portion and/or the tissue thickness compensator which can be utilized to fasten tissue. In use, the fastener cartridge can be positioned in a first jaw of a surgical fastening device, wherein a second jaw, or anvil, can be positioned opposite the first jaw. To deploy the fasteners, a staple-deploying member is advanced through the fastener cartridge to move the fasteners toward the anvil. As the fasteners are deployed, the fasteners can capture at least a portion of the tissue thickness compensator therein along with at least a portion of the tissue being fastened. | 04-05-2012 |
20120080337 | TISSUE THICKNESS COMPENSATOR COMPRISING PORTIONS HAVING DIFFERENT PROPERTIES - A fastener cartridge can comprise a support portion, a tissue thickness compensator positioned relative to the support portion, and a plurality of fasteners positioned within the support portion and/or the tissue thickness compensator which can be utilized to fasten tissue. In use, the fastener cartridge can be positioned in a first jaw of a surgical fastening device, wherein a second jaw, or anvil, can be positioned opposite the first jaw. To deploy the fasteners, a staple-deploying member is advanced through the fastener cartridge to move the fasteners toward the anvil. As the fasteners are deployed, the fasteners can capture at least a portion of the tissue thickness compensator therein along with at least a portion of the tissue being fastened. | 04-05-2012 |
20120080338 | COMPRESSIBLE STAPLE CARTRIDGE ASSEMBLY - A fastener cartridge can comprise a support portion, a tissue thickness compensator positioned relative to the support portion, and a plurality of fasteners positioned within the support portion and/or the tissue thickness compensator which can be utilized to fasten tissue. In use, the fastener cartridge can be positioned in a first jaw of a surgical fastening device, wherein a second jaw, or anvil, can be positioned opposite the first jaw. To deploy the fasteners, a staple-deploying member is advanced through the fastener cartridge to move the fasteners toward the anvil. As the fasteners are deployed, the fasteners can capture at least a portion of the tissue thickness compensator therein along with at least a portion of the tissue being fastened. | 04-05-2012 |
20120080340 | STAPLE CARTRIDGE COMPRISING A VARIABLE THICKNESS COMPRESSIBLE PORTION - A fastener cartridge can comprise a support portion, a tissue thickness compensator positioned relative to the support portion, and a plurality of fasteners positioned within the support portion and/or the tissue thickness compensator which can be utilized to fasten tissue. In use, the fastener cartridge can be positioned in a first jaw of a surgical fastening device, wherein a second jaw, or anvil, can be positioned opposite the first jaw. To deploy the fasteners, a staple-deploying member is advanced through the fastener cartridge to move the fasteners toward the anvil. As the fasteners are deployed, the fasteners can capture at least a portion of the tissue thickness compensator therein along with at least a portion of the tissue being fastened. | 04-05-2012 |
20120080490 | TISSUE THICKNESS COMPENSATOR COMPRISING DETACHABLE PORTIONS - A fastener cartridge can comprise a support portion, a tissue thickness compensator positioned relative to the support portion, and a plurality of fasteners positioned within the support portion and/or the tissue thickness compensator which can be utilized to fasten tissue. In use, the fastener cartridge can be positioned in a first jaw of a surgical fastening device, wherein a second jaw, or anvil, can be positioned opposite the first jaw. To deploy the fasteners, a staple-deploying member is advanced through the fastener cartridge to move the fasteners toward the anvil. As the fasteners are deployed, the fasteners can capture at least a portion of the tissue thickness compensator therein along with at least a portion of the tissue being fastened. | 04-05-2012 |
20120080491 | STAPLE CARTRIDGE COMPRISING COMPRESSIBLE DISTORTION RESISTANT COMPONENTS - A fastener cartridge can comprise a support portion, a tissue thickness compensator positioned relative to the support portion, and a plurality of fasteners positioned within the support portion and/or the tissue thickness compensator which can be utilized to fasten tissue. In use, the fastener cartridge can be positioned in a first jaw of a surgical fastening device, wherein a second jaw, or anvil, can be positioned opposite the first jaw. To deploy the fasteners, a staple-deploying member is advanced through the fastener cartridge to move the fasteners toward the anvil. As the fasteners are deployed, the fasteners can capture at least a portion of the tissue thickness compensator therein along with at least a portion of the tissue being fastened. | 04-05-2012 |
20120080493 | SURGICAL STAPLER WITH FLOATING ANVIL - A surgical instrument can include an anvil and, in addition, a staple cartridge support configured to support a staple cartridge. In various embodiments, the jaw can be moved toward the staple cartridge to deform staples contained within the staple cartridge. The anvil can be configured to be translated and/or rotated as the anvil is moved toward the staple cartridge. In certain embodiments, the anvil can be configured to float and adjust such that the anvil is moved downwardly in a level manner. | 04-05-2012 |
20120080498 | CURVED END EFFECTOR FOR A STAPLING INSTRUMENT - A staple cartridge for use with a surgical stapler can comprise a cartridge deck and a plurality of staples at least partially positioned within the cartridge deck. In various embodiments, the staples can be supported by a support jaw of the surgical stapler and can comprise legs which can extend upwardly through apertures defined in the cartridge deck. The support jaw can comprise stationary staple drivers which can support the staples in curved rows as the staples are deformed by an anvil of the surgical stapler. In certain embodiments, the staple cartridge can further comprise a plurality of staple drivers which can be configured to support and eject the staples along curved staple rows. | 04-05-2012 |
20120083833 | STAPLE CARTRIDGE COMPRISING A RELEASABLE PORTION - A fastener cartridge can comprise a support portion, a tissue thickness compensator positioned relative to the support portion, and a plurality of fasteners positioned within the support portion and/or the tissue thickness compensator which can be utilized to fasten tissue. In use, the fastener cartridge can be positioned in a first jaw of a surgical fastening device, wherein a second jaw, or anvil, can be positioned opposite the first jaw. To deploy the fasteners, a staple-deploying member is advanced through the fastener cartridge to move the fasteners toward the anvil. As the fasteners are deployed, the fasteners can capture at least a portion of the tissue thickness compensator therein along with at least a portion of the tissue being fastened. | 04-05-2012 |
20120083834 | COMPRESSIBLE STAPLE CARTRIDGE COMPRISING ALIGNMENT MEMBERS - A fastener cartridge can comprise a support portion, a tissue thickness compensator positioned relative to the support portion, and a plurality of fasteners positioned within the support portion and/or the tissue thickness compensator which can be utilized to fasten tissue. In use, the fastener cartridge can be positioned in a first jaw of a surgical fastening device, wherein a second jaw, or anvil, can be positioned opposite the first jaw. To deploy the fasteners, a staple-deploying member is advanced through the fastener cartridge to move the fasteners toward the anvil. As the fasteners are deployed, the fasteners can capture at least a portion of the tissue thickness compensator therein along with at least a portion of the tissue being fastened. | 04-05-2012 |
20120083835 | STAPLE CARTRIDGE COMPRISING A TISSUE THICKNESS COMPENSATOR - A fastener cartridge can comprise a support portion, a tissue thickness compensator positioned relative to the support portion, and a plurality of fasteners positioned within the support portion and/or the tissue thickness compensator which can be utilized to fasten tissue. In use, the fastener cartridge can be positioned in a first jaw of a surgical fastening device, wherein a second jaw, or anvil, can be positioned opposite the first jaw. To deploy the fasteners, a staple-deploying member is advanced through the fastener cartridge to move the fasteners toward the anvil. As the fasteners are deployed, the fasteners can capture at least a portion of the tissue thickness compensator therein along with at least a portion of the tissue being fastened. | 04-05-2012 |
20120083836 | STAPLE CARTRIDGE COMPRISING AN ADJUSTABLE DISTAL PORTION - A fastener cartridge can comprise a support portion, a tissue thickness compensator positioned relative to the support portion, and a plurality of fasteners positioned within the support portion and/or the tissue thickness compensator which can be utilized to fasten tissue. In use, the fastener cartridge can be positioned in a first jaw of a surgical fastening device, wherein a second jaw, or anvil, can be positioned opposite the first jaw. To deploy the fasteners, a staple-deploying member is advanced through the fastener cartridge to move the fasteners toward the anvil. As the fasteners are deployed, the fasteners can capture at least a portion of the tissue thickness compensator therein along with at least a portion of the tissue being fastened. | 04-05-2012 |
20120160721 | STAPLE CARTRIDGE LOADING ASSEMBLY - A fastener cartridge can comprise a support portion, a tissue thickness compensator positioned relative to the support portion, and a plurality of fasteners positioned within the support portion and/or the tissue thickness compensator which can be utilized to fasten tissue. In use, the fastener cartridge can be positioned in a first jaw of a surgical fastening device, wherein a second jaw, or anvil, can be positioned opposite the first jaw. To deploy the fasteners, a staple-deploying member is advanced through the fastener cartridge to move the fasteners toward the anvil. As the fasteners are deployed, the fasteners can capture at least a portion of the tissue thickness compensator therein along with at least a portion of the tissue being fastened. | 06-28-2012 |
20120234890 | COLLAPSIBLE ANVIL PLATE ASSEMBLIES FOR CIRCULAR SURGICAL STAPLING DEVICES - Circular stapling instruments and anvil assemblies. The anvil assemblies may have collapsible anvil support members that may be inserted through an opening in a patient and then expanded to be attached to an anvil plate assembly that has a staple-forming surface thereon. The anvil support member is attachable to the anvil plate assembly in such a way that when the anvil assembly is coupled to the stapling head of a circular stapler, the staple-forming surface is in substantial registry with the staples supported in the stapling head. A variety of different anvil support members and anvil plate assemblies are disclosed. | 09-20-2012 |
20120234891 | ANVIL ASSEMBLIES WITH COLLAPSIBLE FRAMES FOR CIRCULAR STAPLERS - Circular stapling instruments and anvil assemblies. The anvil assemblies may have collapsible anvil support members that may be inserted through an opening in a patient and then expanded to be attached to an anvil plate assembly that has a staple-forming surface thereon. The anvil support member is attachable to the anvil plate assembly in such a way that when the anvil assembly is coupled to the stapling head of a circular stapler, the staple-forming surface is in substantial registry with the staples supported in the stapling head. A variety of different anvil support members and anvil plate assemblies are disclosed. | 09-20-2012 |
20120234892 | MULTIPLE PART ANVIL ASSEMBLIES FOR CIRCULAR SURGICAL STAPLING DEVICES - Circular stapling instruments and anvil assemblies. The anvil assemblies may have collapsible anvil support members that may be inserted through an opening in a patient and then expanded to be attached to an anvil plate assembly that has a staple-forming surface thereon. The anvil support member is attachable to the anvil plate assembly in such a way that when the anvil assembly is coupled to the stapling head of a circular stapler, the staple-forming surface is in substantial registry with the staples supported in the stapling head. A variety of different anvil support members and anvil plate assemblies are disclosed. | 09-20-2012 |
20120238824 | SURGICAL BOWEL RETRACTOR DEVICES - Bowel retractor devices. In various forms, the bowel retractor devices are configurable from a collapsed position wherein the retractor may be inserted through a trocar cannula or other opening in a patient's body to a second expanded position wherein at least a portion of the patient's bowel may be advantageously supported in a desired position. | 09-20-2012 |
20120238829 | MODULAR TOOL HEADS FOR USE WITH CIRCULAR SURGICAL INSTRUMENTS - Various universal ports for installation into a colon are disclosed. Some embodiments include means for permitting an anvil of a surgical stapler to pass through a port in a first direction and means for permitting a portion of the patient's colon to pass through the port in a second direction. Some embodiments also employ a flexible sleeve that may extend from the port out through the anus to provide a passageway for passing surgical instruments and into and out of the rectum and also for removing severed specimens therefrom. | 09-20-2012 |
20120239010 | MODULAR SURGICAL TOOL SYSTEMS - Modular surgical instruments are disclosed. In various embodiments, a modular surgical instrument t is disclosed for use with a plurality of interchangeable surgical tool heads that are configured to perform different surgical actions. The instrument is configured to apply a plurality of different rotary drive motions and axial drive motions depending upon the type of surgical tool head attached thereto. | 09-20-2012 |
20120241492 | TISSUE THICKNESS COMPENSATOR COMPRISING AT LEAST ONE MEDICAMENT - In various embodiments, a tissue thickness compensator can comprise one or more capsules and/or pockets comprising at least one medicament therein. In at least one embodiment, staples can be fired through the tissue thickness compensator to rupture the capsules. In certain embodiments, a firing member, or knife, can be advanced through the tissue thickness compensator to rupture the capsules. | 09-27-2012 |
20120241496 | TISSUE THICKNESS COMPENSATOR COMPRISING A PLURALITY OF CAPSULES - A tissue thickness compensator can comprise a plurality of layers. Various embodiments are disclosed herein for manufacturing a tissue thickness compensator. In certain embodiments, a tissue thickness compensator can comprise at least one medicament tube, capsule, and/or packet contained therein | 09-27-2012 |
20120241497 | TISSUE THICKNESS COMPENSATOR COMPRISING A RESERVOIR - In various embodiments, a tissue thickness compensator can comprise a compressible extracellular matrix and a bioabsorbable material dispersed within the extracellular matrix, wherein the bioapsorption of the bioabsorbable material is configured to leave behind channels in the extracellular matrix. The tissue thickness compensator can also comprise generation means for generating the ingrowth of tissue into the channels. In at least one embodiment, the tissue thickness compensator can comprise dissolvable wicking members which, when dissolved, can leave behind channels in the tissue thickness compensator. In certain embodiments, the tissue thickness compensator can comprise at least one rupturable capsule. | 09-27-2012 |
20120241499 | RETAINER ASSEMBLY INCLUDING A TISSUE THICKNESS COMPENSATOR - A retainer for assembling tissue thickness compensators to a surgical stapler can comprise a grip, a first surface for supporting a first tissue thickness compensator, a second surface for supporting a second tissue thickness compensator, and clips for aligning and attaching the retainer to the surgical stapler. The clips may align and attach the retainer to a staple cartridge of the surgical instrument. The clips may align the retainer with an anvil of the surgical instrument. An insertion tool may be used in combination with the retainer to insert the retainer into the surgical stapler and to push the tissue thickness compensators against the anvil and/or the staple cartridge of the surgical instrument. | 09-27-2012 |
20120241500 | TISSUE THICKNESS COMPENSATOR COMPRISING FIBERS TO PRODUCE A RESILIENT LOAD - A nonwoven compensator for an end effector of a surgical instrument can comprise a plurality of spring fibers dispersed throughout the nonwoven compensator. The nonwoven compensator can be positioned in the end effector such as adjacent to a deck surface of a fastener cartridge that is positioned in the end effector. When a fastener from the fastener cartridge is moved from an initial position to a fired position, the fastener can be configured to engage the nonwoven compensator. The fastener can compress a portion of the nonwoven compensator in a staple entrapment area defined by the fired staple. The spring fibers in the nonwoven compensator can comprise a resilient material and can be deformed when the fastener compresses a portion of the nonwoven compensator. Further, the nonwoven compensator can comprise non-spring fibers, a haemostatic material, and/or a homogenous absorbable polymer matrix. | 09-27-2012 |
20120241501 | TISSUE THICKNESS COMPENSATOR COMPRISING STRUCTURE TO PRODUCE A RESILIENT LOAD - A fastener cartridge assembly for an end effector of a surgical instrument can comprise a cartridge body, a deformable tube, and a fastener moveable between an initial position and a fired position. The deformable tube can be longitudinally positioned along a length of the cartridge body. When the fastener is moved to the fired position, the fastener can compress a portion of the deformable tube. The deformable tube can comprise a resilient material such that deformation of the deformable tube generates a restoring force. The deformable tube can comprise a lattice of strands woven together to form a tube wall. Further, the deformable tube can be bioabsorbable and can hold a therapeutic agent. The fastener cartridge assembly can comprise multiple, substantially parallel deformable tubes positioned side-by-side and/or within each other. | 09-27-2012 |
20120241502 | TISSUE THICKNESS COMPENSATOR COMPRISING RESILIENT MEMBERS - A tissue thickness compensator comprising at least one woven lattice can be positioned in the end effector of a surgical instrument. A fastener cartridge that is positioned in the end effector can comprise at least one cavity configured to receive a fastener. The fastener can be moveable between an initial position, wherein the fastener is at least partially position in a cavity, and a fired position, wherein the fastener is configured to compress a woven lattice of the tissue thickness compensator. The woven lattice can comprise a resilient material such that compression of the woven lattice generates a restoring force. The woven lattice can also comprise an axis that can laterally traverse the fastener cartridge, diagonally traverse the fastener cartridge, or intersect a deck surface of the fastener cartridge. The woven lattice can comprise a hydrophilic substance, which can expand when the woven lattice is severed by a cutting element. | 09-27-2012 |
20120241503 | TISSUE THICKNESS COMPENSATORS - A two-part tissue thickness compensator assembly can include a first tissue thickness compensator configured to be positioned relative to an anvil of a surgical stapler, a second tissue thickness compensator configured to be positioned relative to a staple cartridge of the surgical stapler, and a hinge connecting the first tissue thickness compensator to the second tissue thickness compensator. The first and/or second tissue thickness compensators may include additional engagement features, such as a raised ridge that engages a slot in the anvil and/or the staple cartridge. In certain embodiments, the first and/or second tissue thickness compensators may include an encasement that contains a suitable biologic agent. An end effector assembly may be provided for attachment to a surgical instrument that includes, for example, a staple cartridge, an anvil, a first tissue thickness compensator positioned on the anvil, and a second tissue thickness compensator positioned on the staple cartridge. | 09-27-2012 |
20120253298 | LAYERED TISSUE THICKNESS COMPENSATOR - A tissue thickness compensator may generally comprise a first layer comprising a first medicament, a second layer comprising a second medicament, and a third layer comprising a third medicament. The tissue thickness compensator may comprise a first layer comprising a first medicament, a second layer comprising a second medicament, and a reservoir comprising a third medicament disposed within the reservoir. The medicaments may be independently selected from a haemostatic agent, an anti-inflammatory agent, an antibiotic agent, anti-microbial agent, an anti-adhesion agent, an anti-coagulant agent, a pharmaceutically active agent, a matrix metalloproteinase inhibitor, and combinations thereof. Articles of manufacture comprising the tissue thickness compensator and methods of making and using the tissue thickness compensator are also described. | 10-04-2012 |
20120318843 | TISSUE STAPLER HAVING A THICKNESS COMPENSATOR INCORPORATING AN OXYGEN GENERATING AGENT - A staple cartridge assembly for use with a surgical stapler. The assembly has a cartridge body having a support portion with a plurality of staple cavities with openings. There is also a plurality of staples, wherein at least a portion of each the staple is removably stored within a the staple cavity. Each the staple is movable between an unfired position and a fired position, and is deformable between an unfired configuration and a fired configuration. The assembly also includes a compressible tissue thickness compensator configured to be captured within the staples. The compressible tissue thickness compensator at least partially covers the staple cavity openings. The compressed tissue thickness compensator is configured to assume different compressed heights within different the staples. The compressible tissue thickness compensator comprising a lyophilized foam having an oxygen generating agent embedded therein. | 12-20-2012 |
20130075448 | STAPLE CARTRIDGE INCLUDING COLLAPSIBLE DECK ARRANGEMENT - A staple cartridge for use with a surgical stapler can comprise a cartridge deck and a plurality of staples at least partially positioned within the cartridge deck. In various embodiments, the staples can comprise legs which extend upwardly from the deck wherein the deck can further include supports, or guides, which are configured to hold the staple legs in a particular alignment. In at least one such embodiment, the staple legs can extend upwardly from the supports into a tissue thickness compensator. | 03-28-2013 |
20130075449 | SURGICAL STAPLER WITH STATIONARY STAPLE DRIVERS - A staple cartridge for use with a surgical stapler can comprise a cartridge deck and a plurality of staples at least partially positioned within the cartridge deck. In various embodiments, the staples can be supported by a support jaw of the surgical stapler and can comprise legs which can extend upwardly through apertures defined in the cartridge deck. In use, the cartridge deck can be pushed downwardly relative to the staples into a well defined in the support jaw. | 03-28-2013 |
20130075450 | STAPLE CARTRIDGE INCLUDING COLLAPSIBLE DECK - A staple cartridge for use with a surgical stapler can comprise a cartridge deck and a plurality of staples at least partially positioned within the cartridge deck. In use, the staples can be supported by a first jaw of the surgical stapler and deformed by a second jaw. As the staples are being deformed, the cartridge deck can be pushed, or slid, downwardly relative to the staples. | 03-28-2013 |
20130146641 | ACTUATOR FOR RELEASING A LAYER OF MATERIAL FROM A SURGICAL END EFFECTOR - An end effector assembly for use with a surgical instrument. The end effector assembly can comprise an anvil, a fastener cartridge including fastener cavities, fasteners removably positioned in the fastener cavities, a piece of buttress material releasably secured intermediate the anvil and the fastener cartridge, a connector, and an actuator configured to overcome the connector when actuated. The connector can secure the piece of buttress material relative to the anvil or the fastener cartridge at a location that is distal to at least one fastener cavity. The actuator can overcome the connector prior to the removal of the fasteners from the fastener cavities. Further, the actuator can extend past the fasteners in the fastener cavities, and can be actuated proximal to the fastener cavities. | 06-13-2013 |
20130214030 | ACTUATOR FOR RELEASING A TISSUE THICKNESS COMPENSATOR FROM A FASTENER CARTRIDGE - A fastener cartridge assembly for use with a surgical end effector. The fastener cartridge assembly can comprise a cartridge body having fastener cavities, fasteners removably positioned in the fastener cavities, a layer of material releasably secured relative to the cartridge body, a connector configured to secure the layer of material to the cartridge body at a location distal to at least one fastener cavity, and an actuator. The layer of material can be a tissue thickness compensator. When actuated, the actuator can overcome the connector, and can overcome the connector prior to the removal of the fasteners from the fastener cavities. The actuator can be actuated at a location proximal to at least one fastener cavity, and can extend distally past at least one fastener cavity toward the connector. | 08-22-2013 |
20130221063 | RELEASABLE TISSUE THICKNESS COMPENSATOR AND FASTENER CARTRIDGE HAVING THE SAME - A fastener cartridge assembly for use with a surgical end effector. The fastener cartridge assembly can comprise a cartridge body, fasteners, and a layer of material releasably secured to the cartridge body. The layer of material can be a tissue thickness compensator. The cartridge body, the fasteners, the tissue thickness compensator and/or the end effector can comprise various features to releasably secure the tissue thickness compensator relative to the cartridge body. For example, the cartridge body can comprise slots, projections, cavities, drivers, locks, and/or keys, the fasteners can comprise barbs, and/or the tissue thickness compensator can comprise mounts and/or connectors. | 08-29-2013 |
20130221064 | FASTENER CARTRIDGE COMPRISING A RELEASABLE TISSUE THICKNESS COMPENSATOR - A fastener cartridge can comprise, one, a cartridge body configured to at least partially store a plurality of fasteners therein and, two, a layer of material attached to the cartridge body by a retention member. The retention member can be deactivated to release the layer from the cartridge body when a firing member is moved through the cartridge body to eject the fasteners from the cartridge body. The retention member can be deactivated at the beginning, the end, and/or at any suitable time during a firing stroke of the firing member. Certain fastener cartridges can comprise a plurality of retention members configured to releasably hold the layer to the cartridge body. In certain circumstances, the retention members can be sequentially released in order to progressively release the layer. | 08-29-2013 |
20130221065 | FASTENER CARTRIDGE COMPRISING A RELEASABLY ATTACHED TISSUE THICKNESS COMPENSATOR - A fastener cartridge can comprise a cartridge body and a layer, such as a tissue thickness compensator, for example, releasably attached to the cartridge body. The tissue thickness compensator can comprise a compressible first portion and a second support portion. The second portion can be rigid and can support the first portion when mounted thereto. The properties of the first portion and/or the second portion can be selected so as to prevent the premature deflection and release from the cartridge body. The fastener cartridge can further comprise one or more attachment portions configured to releasably hold the tissue thickness compensator to the cartridge body. The attachment portions can be configured to permit a firing member to pass therethrough. In some circumstances, the tissue thickness compensator can be configured to hold the firing member in an unfired position until a sufficient firing force has been applied to the firing member. | 08-29-2013 |
20130256365 | TISSUE THICKNESS COMPENSATOR COMPRISED OF A PLURALITY OF MATERIALS - In various embodiments, a tissue thickness compensator can comprise a plurality of fibers. In at least one embodiment, such fibers can include a plurality of first fibers comprised of a first material and a plurality of second fibers comprised of a second material. A tissue thickness compensator can comprise a plurality of layers wherein each layer can be comprised of one or more medicaments. Certain embodiments are disclosed herein for manufacturing a tissue thickness compensator comprising fibers, for example. | 10-03-2013 |
20130256372 | TISSUE THICKNESS COMPENSATOR COMPRISING CAPSULES DEFINING A LOW PRESSURE ENVIRONMENT - A tissue thickness compensator can comprise a compensator body and at least one vessel contained in the compensator body. The vessel can define an inner cavity which can comprise an inner atmosphere having a pressure which is lower than the atmospheric pressure of the atmosphere surrounding the tissue thickness compensator. In at least one embodiment, the vessel and the compensator body can be maintained in a collapsed state until staples are fired through the vessel. At such point, the vessel can re-expand and apply a biasing force to tissue captured within the staples. | 10-03-2013 |
20130256373 | DEVICES AND METHODS FOR ATTACHING TISSUE THICKNESS COMPENSATING MATERIALS TO SURGICAL STAPLING INSTRUMENTS - Surgical stapling instruments are disclosed. At least one embodiment includes a first jaw that supports a plurality of surgical staples and a second jaw that is movable relative to the first jaw. Various arrangements include a tissue thickness compensator that is configured to be captured within the surgical staples and assume different compressed heights within different surgical staples upon application of a firing motion to the surgical staples. Various attachment protrusion arrangements are disclosed to mechanically removably attach the tissue thickness compensator to the first or second jaw. | 10-03-2013 |
20130256377 | LAYER COMPRISING DEPLOYABLE ATTACHMENT MEMBERS - An anvil-attachable layer and a retainer for aligning and attaching the layer to an anvil of a surgical stapler. Embodiments of the anvil-attachable layer can include one or more attachment features extending from the layer. A retainer can push the attachment features into a knife slot in the anvil so that the fit between the attachment features and the slot hold the anvil-attachable layer in place. Other embodiments of the anvil-attachable layer can include deployable attachment features formed in the layer. The deployable attachment features can be deployed from an undeployed position substantially in a plane defined by the layer to a deployed position extending out of the plane. In the deployed position, the deployable attachment features can extend into a slot in an anvil. A retainer can include features to push the deployable attachment features into the deployed position. | 10-03-2013 |
20130256383 | ANVIL LAYER ATTACHED TO A PROXIMAL END OF AN END EFFECTOR - An anvil-attachable layer for use with a surgical stapler, or fastening instrument, wherein a proximal end portion of the layer is attached to a staple cartridge assembly, for example. The layer may be attached to the staple cartridge assembly by an adhesive, weld, or a staple-cartridge-based clamp, wherein the attachment is weak enough to allow the layer to pull away from the staple cartridge assembly with stapled tissue. Alternatively, the layer can include two or more lateral slits that define a connector region that can be cut by a knife of a surgical stapler to release the layer. | 10-03-2013 |
20140018767 | METHODS AND DEVICES FOR ACTIVATING BROWN ADIPOSE TISSUE WITH TARGETED SUBSTANCE DELIVERY - Methods and devices are provided for activating brown adipose tissue with targeted substance delivery. Generally, the methods and devices can activate BAT to increase thermogenesis, e.g., increase heat production in the patient, which over time can lead to weight loss and/or improved metabolic function. In one embodiment, a chemical configured to stimulate nerves that activate the BAT and/or to stimulate brown adipocytes directly can be delivered to a patient, thereby increasing thermogenesis in the BAT and inducing weight loss and/or improved metabolic function through energy expenditure. The chemical can be delivered to the patient locally and/or systemically to stimulate the nerves and/or the brown adipocytes. | 01-16-2014 |
20140051950 | USE OF BIOMARKERS AND THERAPEUTIC AGENTS WITH SURGICAL DEVICES - Biomarkers are collected and used to determine biological propensities of a patient, to determine the efficacy of medical devices, to select and administer therapeutic agents, to select medical devices, to make adjustments to medical devices, and/or to adjust surgical techniques. An apparatus includes a port to draw a biological fluid (e.g., a mist) from a surgical site. The apparatus includes a sensor having a cantilevered beam. The beam includes substances selected to attract certain biomarkers as the fluid is communicated across the beam. The same apparatus or another apparatus is used to administer a therapeutic agent based at least in part on collected biomarker data. The therapeutic agent delivery apparatus may include a device that is also used to create a wound at a surgical site. For instance, a harmonic surgical instrument may be used to both collect biomarkers and administer a therapeutic agent (e.g., gene therapy using sonoporation). | 02-20-2014 |
20140088487 | METHODS AND DEVICES FOR ACTIVATING BROWN ADIPOSE TISSUE WITH LIGHT - Methods and devices are provided for activating brown adipose tissue (BAT) with light. Generally, the methods and devices can activate BAT to increase thermogenesis, e.g., increase heat production in the patient, which over time can lead to weight loss and/or improved metabolic function. In one embodiment, a medical device is provided that activates BAT by using light to stimulate nerves that activate the BAT and/or to stimulate brown adipocytes directly, thereby increasing thermogenesis in the BAT and inducing weight loss and/or improved metabolic function through energy expenditure. The light can be configured to directly or indirectly stimulate the nerves and/or the brown adipocytes. The light can be configured to indirectly stimulate the nerves and/or the brown adipocytes by activating a light activatable medium administered to a patient and configured to respond to the light to cause activation of the brown adipose tissue. | 03-27-2014 |
20140097227 | FASTENER CARTRIDGE COMPRISING A CUTTING MEMBER FOR RELEASING A TISSUE THICKNESS COMPENSATOR - A staple cartridge, or fastener cartridge, for a surgical stapler, or fastening instrument, wherein the staple cartridge includes a distally-located cutting blade arranged to cut a distal end portion of a layer, such as a tissue thickness compensator and/or a buttress material, for example, attached to the staple cartridge. The distally-located cutting blade can extend out of a distal cavity of the staple cartridge. The distally-located cutting blade can move in a direction that is perpendicular to a staple deck of the staple cartridge. The distally-located cutting blade can also move in any suitable direction relative to the staple deck. | 04-10-2014 |
20140158741 | ELECTROSURGICAL END EFFECTOR WITH TISSUE TACKING FEATURES - An apparatus is provided for operating on tissue. The apparatus includes an end effector having an upper jaw and lower jaw. The upper and lower jaws each include an electrode surface. The apparatus also includes a tissue tacking cartridge coupled to one of either the upper jaw or the lower jaw. The tissue tacking cartridge includes at least one fastener positioned outside of the electrode surfaces. The fastener is operable to be deployed from the tissue tacking cartridge. A tack loading cartridge may also be operable to load the end effector with at least one fastener. | 06-12-2014 |
20140166724 | STAPLE CARTRIDGE INCLUDING A BARBED STAPLE - A staple cartridge is disclosed which includes a cartridge body and a plurality of staples removably stored therein. The staples can include at least one barb extending therefrom. A first group of the staples can have a first unformed height and a second group of the staples can have a second unformed height. A first group of the staples can have a first formed height and a second group of the staples can have a second formed height. | 06-19-2014 |
20140166725 | STAPLE CARTRIDGE INCLUDING A BARBED STAPLE. - An end effector for fastening tissue including an anvil having a deck to support tissue. The deck has a first surface with a first longitudinal row of staple forming pockets, and a second surface, having a second longitudinal row of staple forming pockets wherein the first surface is positioned vertically above the second surface. The end effector also includes a cartridge having plurality of staple cavities arranged in first and second longitudinal rows. The end effector also includes a plurality of staples removably stored within the staple cavities. The staples include a base, a pair of legs extending from the base, wherein each the leg comprises a tip configured to pierce tissue, and wherein each the leg comprises at least one barb extending therefrom. The end effector also has a firing member configured to lift the staple drivers toward the anvil. | 06-19-2014 |
20140166726 | STAPLE CARTRIDGE INCLUDING A BARBED STAPLE - An end effector for fastening tissue including a cartridge having a longitudinal row of staple cavities and a plurality of staples removably stored in the staple cavities. The staple includes a base, a pair of legs extending from the base, and a plane formed by the pair of legs, wherein at least one of the legs has a barb extending therefrom. The barb extends from the leg less than 360 degrees around the leg, wherein the barb extends beyond the plane formed by the legs. The end effector also includes an anvil configured to deform the staples, and a plurality of staple drivers movable within the cavities configured to lift the staples toward the anvil. The end effector further includes a firing member, configured to lift the staple driver system toward the anvil, including a first portion configured to engage the anvil and a second portion configured to engage the cartridge. The firing member is configured to relatively position the anvil and the cartridge. | 06-19-2014 |
20140199278 | BROWN ADIPOCYTE MODIFICATION - Methods and therapeutics are provided for treating metabolic disorders by increasing activation of brown adipose tissue. Generally, the methods and therapeutics can increase activation of brown adipose tissue to increase energy expenditure and induce weight loss. In one embodiment, a method for increasing activation of brown adipose tissue includes modifying brown adipocytes to express a gene that activates brown adipocytes, such as uncoupling protein 1. In another embodiment, a method for increasing brown adipose tissue activation includes increasing the number of brown adipocytes. This can be accomplished by inducing proliferation of adipocytes in vivo or expanding adipocytes ex vivo, transplanting adipocytes into brown adipose tissue depots or elsewhere and inducing differentiation of adipocyte progenitor cells, such as MSCs, adipocyte progenitor cells, pre-adipocytes and adipocyte precursor cells. | 07-17-2014 |
20140214019 | BIPOLAR ELECTROSURGICAL HAND SHEARS - An apparatus comprises a first jaw, a second jaw, a first handle, and a second handle. The second jaw is pivotally coupled with the first jaw. The first jaw and the second jaw are configured to grasp tissue. The jaws provide offset electrode surfaces that are operable to deliver bipolar RF energy to tissue grasped between the jaws. The apparatus is further operable to sever tissue. A lockout feature selectively prevents tissue severing, based on an energization state of the jaws. | 07-31-2014 |
20140252068 | STAPLE CARTRIDGE COMPRISING A RELEASABLE PORTION - A staple cartridge includes a plurality of staples, wherein each said staple comprises a base and a deformable leg extending from said base. The staple cartridge further includes a first region comprising a first density, a second region, and a third region comprising a density greater than said first density, wherein said third region is separable into a plurality of pieces. | 09-11-2014 |
20140291379 | TISSUE THICKNESS COMPENSATOR COMPRISING A CUTTING MEMBER PATH - A fastener cartridge can comprise a support portion, a tissue thickness compensator positioned relative to the support portion, and a plurality of fasteners. In use, the fastener cartridge can be arranged in a jaw of a surgical fastening device. To deploy the fasteners, a staple-deploying member is advanced through the fastener cartridge to move the fasteners toward an anvil wherein the fasteners can capture at least a portion of the tissue thickness compensator therein along with at least a portion of the tissue being fastened. The cartridge body can further comprise a first knife path configured to receive a cutting member and the tissue thickness compensator can further comprise a second knife path aligned with the first knife path. The second knife path can comprise different portions configured to apply different resistances to the cutting member as the cutting member is advanced through the fastener cartridge. | 10-02-2014 |
20140291380 | FASTENER CARTRIDGE COMPRISING A TISSUE THICKNESS COMPENSATOR AND A GAP SETTING ELEMENT - A fastener cartridge can comprise a support portion, a tissue thickness compensator positioned relative to the support portion, and a plurality of fasteners positioned within the support portion and/or the tissue thickness compensator which can be utilized to fasten tissue. In use, the fastener cartridge can be arranged in a first jaw of a surgical fastening device, wherein a second jaw, or anvil, can be positioned opposite the first jaw. To deploy the fasteners, a staple-deploying member is advanced through the fastener cartridge to move the fasteners toward the anvil. As the fasteners are deployed, the fasteners can capture at least a portion of the tissue thickness compensator therein along with at least a portion of the tissue being fastened. The fastener cartridge can further comprise a gap setting element which can be configured to control the distance between the anvil, the support portion, and/or the tissue thickness compensator. | 10-02-2014 |
20140291381 | FASTENER CARTRIDGE ASSEMBLIES - A fastener cartridge assembly. The fastener cartridge assembly can comprise a fastener, a cartridge body, and a tissue thickness compensator. The fastener can comprise a base, a first leg extending from the base, and a second leg extending from the base. The cartridge body can comprise a fastener cavity for receiving the fastener and a trajectory control for controlling the trajectory of the first and second legs of the fastener. The fastener can be removable from the fastener cavity along a fastener axis. The trajectory control can extend inwardly toward the fastener axis and can bias the first leg and the second leg toward alignment with the fastener axis when the fastener is positioned in the fastener cavity. | 10-02-2014 |
20140291382 | FASTENER CARTRIDGE COMPRISING A TISSUE THICKNESS COMPENSATOR INCLUDING OPENINGS THEREIN - A fastener cartridge assembly. The fastener cartridge assembly can comprise a cartridge body, a tissue thickness compensator releasably secured relative to the cartridge body, and a fastener removably positioned in a staple cavity of the cartridge body. The tissue thickness compensator can comprise a first clearance aperture extending along a first predefined trajectory and a second clearance aperture extending along a second predefined trajectory. The fastener can comprise a first leg aligned with the first clearance aperture and moveable along the first predefined trajectory, a second leg aligned with the second clearance aperture and moveable along the second predefined trajectory. The first and second predefined trajectories can be parallel. | 10-02-2014 |
20150080891 | ELECTROSURGICAL (RF) MEDICAL INSTRUMENTS FOR CUTTING AND COAGULATING TISSUE - An electrosurgical device is disclosed. The electrosurgical device includes a handle, a shaft extending distally from the handle, and an end effector coupled to a distal end of the shaft. The end effector comprises a first electrode and a second electrode. The second electrode includes a first position and a second position. The second electrode is configured to move from the first position to the second position when a force is applied to the end effector by a tissue section. The first electrode and the second electrode define a treatment area when the second electrode is in the second position. | 03-19-2015 |