Patent application number | Description | Published |
20090282784 | Packaging Material Sterilizing Unit for a Pourable Food Product Packaging Machine - There is described a unit (3) for sterilizing a web (2) of packaging material, the unit having a bath (5) containing a sterilizing agent in which the web (2) is advanced continuously; and an aseptic environment (27) containing sterile air, connected to an outlet (10) of the bath (5), and housing drying means (15) for removing residual sterilizing agent from the web (2); the aseptic environment (27) is divided into two regions (23, 6) by a narrow-section channel (28), along which the web (2) travels, and which is sized to produce a predetermined difference in pressure between the two regions (23, 6), and so force air into the channel (28) from the higher-pressure region (23) to the lower-pressure region (6) to dry the web (2). | 11-19-2009 |
20130118125 | METHOD OF STERILIZING A WEB OF PACKAGING MATERIAL - There is described a unit for sterilizing a web of packaging material, the unit having a bath containing a sterilizing agent in which the web is advanced continuously; and an aseptic environment containing sterile air, connected to an outlet of the bath, and housing drying means for removing residual sterilizing agent from the web; the aseptic environment is divided into two regions by a narrow-section channel, along which the web travels, and which is sized to produce a predetermined difference in pressure between the two regions, and so force air into the channel from the higher-pressure region to the lower-pressure region to dry the web. | 05-16-2013 |
Patent application number | Description | Published |
20090048337 | Modulation of anxiety through blockade of anandamide hydrolysis - Fatty acid amide hydrolase inhibitors of the Formula: | 02-19-2009 |
20100267836 | NOVEL MELATONIN LIGANDS HAVING ANTIDEPRESSANT ACTIVITY AS WELL AS SLEEP INDUCING PROPERTIES - Novel melatonin ligands of Formula I: | 10-21-2010 |
20120010283 | MODULATION OF ANXIETY THROUGH BLOCKADE OF ANANDAMIDE HYDROLYSIS - Fatty acid amide hydrolase inhibitors of the Formula: | 01-12-2012 |
20130217764 | PERIPHERALLY RESTRICTED FAAH INHIBITORS - Peripherally restricted inhibitors of fatty acid amide hydrolase (FAAH) are provided. The compounds can suppress FAAH activity and increases anandamide levels outside the central nervous system (CNS). Despite their relative inability to access brain and spinal cord, the compounds attenuate behavioral responses indicative of persistent pain in rodent models of inflammation and peripheral nerve injury, and suppresses noxious stimulus-evoked neuronal activation in spinal cord regions implicated in nociceptive processing. CBi receptor blockade prevents these effects. Accordingly, the invention also provides methods, and pharmaceutical compositions for treating conditions in which the inhibition of peripheral FAAH would be of benefit. The compounds of the invention are according to the formula (I): in which R | 08-22-2013 |
20130281490 | Disubstituted Beta-lactones as Inhibitors of N-Acylethanolamine Acid Amidase (NAAA) - The present invention provides compounds and pharmaceutical compositions for inhibiting N-acylethanolamine acid amidase (NAAA). Inhibition of NAAA is contemplated as a method to sustain the levels of palmitoylethanolamide (PEA) and oleylethanolamide (OEA), two substrates of NAAA, in conditions characterized by reduced concentrations of PEA and OEA. The invention also provides methods for treating inflammatory diseases and pain, and other disorders in which decreased levels of PEA and OEA are associated with the disorder. | 10-24-2013 |
20140094508 | COMPOSITIONS AND METHODS OF INHIBITING N-ACYLETHANOLAMINE-HYDROLYZING ACID AMIDASE - Compounds and pharmaceutical compositions are contemplated that inhibit N-acyl-ethanolamine-hydrolyzing acid amidase (NAAA) to so increase the concentration of the substrate of NAAA, palmitoylethanolamide (PEA). NAAA inhibition is contemplated to be effective to alleviate conditions associated with a reduced concentration of PEA. Among other uses, various NAAA inhibitors are especially contemplated as therapeutic agents in the treatment of inflammatory diseases. | 04-03-2014 |
20140288170 | META-SUBSTITUTED BIPHENYL PERIPHERALLY RESTRICTED FAAH INHIBITORS - The present invention provides methods of making and using peripherally restricted inhibitors of fatty acid amide hydrolase (FAAH). The present invention provides compounds and compositions that suppress FAAH activity and increases anandamide levels outside the central nervous system (CNS). The present invention also sets forth methods for inhibiting FAAH as well as methods for treating conditions such as, but not limited to, pain, inflammation, immune disorders, dermatitis, mucositis, the over reactivity of peripheral sensory neurons, neurodermatitis, and an overactive bladder. Accordingly, the invention also provides compounds, methods, and pharmaceutical compositions for treating conditions in which the selective inhibition of peripheral FAAH (as opposed to CNS FAAH) would be of benefit. | 09-25-2014 |
20150045442 | NOVEL MELATONIN LIGANDS HAVING ANTIDEPRESSANT ACTIVITY AS WELL AS SLEEP INDUCING PROPERTIES - Novel melatonin ligands of Formula I: | 02-12-2015 |