Tang, GB
Christoph Tang, Oxford GB
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20150190494 | NEISSERIA MENINGITIDIS FHBP VARIANT AND ITS USE FOR VACCINATION - The invention relates to a modified V2 fHbp having increased stability over a wild type V2 fHbp; a modified V2 fHbp having an amino acid sequence with at least 85% identity to the sequence of Seq ID No: 1, wherein both Ser | 07-09-2015 |
Christoph Marcel Tang, Oxford GB
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20160030544 | IMMUNOGENIC COMPOSITION TO NEISSERIA - The present invention provides an immunogenic composition capable of eliciting an immune response when administered to a human or non-human animal, wherein the composition comprises an isolated protein with one or more of the following properties: i) about 70, 75, 80, 85, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99 or more percent sequence identity to the protein of SEQ ID No: 1 or a fragment, derivative or analog thereof; ii) is a modified factor H binding protein, wherein the factor H binding protein has been modified at least at the position equivalent to position 318 as defined in FIG. | 02-04-2016 |
Jianming Tang, Chelmsford Essex GB
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20130272698 | ADAPTIVE BIT OR POWER LOADING IN OPTICAL ORTHOGONAL FREQUENCY DIVISION MULTIPLEXING TRANSCEIVERS - The present invention discloses a method for real time optical orthogonal frequency division multiplexing (OOFDM) transceivers by adaptively utilising available channel spectral characteristics. | 10-17-2013 |
Jianming Tang, Harlow Essex GB
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20120224854 | USE OF THE SAME SET OF WAVELENGTHS FOR UPLINK AND DOWNLINK SIGNAL TRANSMISSION - The present invention relates to the field of signal transmission using orthogonal optical frequency division multiplexing transceivers and to the use of the same set of wavelengths for the downlink and uplink signal transmission. | 09-06-2012 |
20120230686 | SYNCHRONIZATION PROCESS IN OPTICAL FREQUENCY DIVISION MULTIPLEXING TRANSMISSION SYSTEMS - The present invention discloses a synchronisation method suitable for increasing the receiving speed in the receiving part of an orthogonal optical frequency division multiplexing (OOFDM) transceiver. | 09-13-2012 |
20120243876 | USE OF SEMICONDUCTOR OPTICAL AMPLIFIERS-BASED INTENSITY MODULATOR IN SIGNAL TRANSMISSION - The present invention discloses the use of a semiconductor optical amplifier in a transceiver in order to increase the number of end users without reducing the bandwidth allocated to each user. | 09-27-2012 |
Jianming Tang, Chelmsford GB
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20130108271 | SYNCHRONOUS CLOCKING FOR OPTICAL ORTHOGONAL FREQUENCY DIVISION MULTIPLEXING TRANSMISSION SYSTEMS | 05-02-2013 |
20140056583 | SYMBOL ALIGNMENT IN HIGH SPEED OPTICAL ORTHOGONAL FREQUENCY DIVISION MULTIPLEXING TRANSMISSION SYSTEMS - The present invention discloses a method for symbol synchronisation in high speed optical orthogonal frequency division multiplexing (OOFDM) transmission systems via coding the electrical OFDM symbols by adding an independent low power-level alignment signal, converting the encoded signal into the optical domain for transmission, and in the receiver converting the received optical signal to the electrical domain and digitally processing to detect the symbol alignment offset by utilising the independent low-power level alignment signal. The present invention is suitable for point-to-point and point-to-multi-point OOFDM networks and has the additional features of timeslot and frame alignment, compensation for receiver sampling clock offset and providing physical layer network security. The superimposed training signal is a DC offset whose value varies at symbol transitions. | 02-27-2014 |
Ke Tang, Cambridge GB
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20080235152 | ACHIEVEMENT AND PRESERVATION FUNDS - A computer-implemented method of locking-in investment gains can include initializing an investment fund having a net asset value per share. The investment fund can include assets allocated to at least a discount instrument and a derivative instrument, where the discount instrument provides a floor value of the net asset value per share. The method can further include selecting a target value for the investment fund. In addition, in some instances, the method can include reinitializing the investment fund in response to one or more of the following: (a) the investment fund at least achieving the target value and (b) expiration of an investment period of the investment fund. Reinitializing the investment fund can include rolling over the assets of the investment fund. | 09-25-2008 |
Kim-Wah Tang, Sandwich GB
Kin-Wah Tang, Sandwich GB
Lai Chiu Tang, Cambridge GB
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20150174346 | DRY POWDER INHALER - The present invention relates to a dry powder inhaler for administering a medicament via oral inhalation route to a subject. Particularly, the dry powder inhaler according to present invention is suitable for delivering accurate doses of a medicament in different ranges of inspiratory capacity of the subject. | 06-25-2015 |
Mengxing Tang, Leicester GB
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20100148798 | Apparatus and Method for Electrical Impedance Imaging - An apparatus | 06-17-2010 |
Qiao Tang, Cardiff GB
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20100121813 | METHOD OF COMPARING DATA SEQUENCES - A method according to the present invention enables the similarity between sequences of symbols to be determined using rules generated from a dictionary-based compression scheme according to the content of the columns from databases. Pairs of symbols can replaced by rules that do not comprise a repeated combination of two symbols and where each rule occurs more than once in the sequence of symbols. The similarity of each set of rules can then be expressed numerically. | 05-13-2010 |
Richard W. Cheong Tang, Middlesex GB
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20120076310 | Automatic Identification of Repeated Material In Audio Signals - A system and method are described for recognizing repeated audio material within at least one media stream without prior knowledge of the nature of the repeated material. The system and method are able to create a screening database from the media stream or streams. An unknown sample audio fragment is taken from the media stream and compared against the screening database to find if there are matching fragments within the media streams by determining if the unknown sample matches any samples in the screening database. | 03-29-2012 |
Weijun Tang, Liverpool GB
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20150073165 | CATALYST COMPOUNDS - The present invention relates to an iridium-based catalyst compound for hydrogenating reducible moieties, especially imines and iminiums, the catalyst compounds being defined by the formula: (Formula (I)) where ring B is a conjugated ring system with one or more substituents. The catalysts of the invention are particularly effective in reductive amination procedures which involve the in situ generation of the imine or iminium under reductive hydrogenative conditions. | 03-12-2015 |
20150080592 | CATALYST COMPOUNDS - The present invention relates to an iridium-based catalyst compound for hydrogenating reducible moieties, especially imines and iminiums, the catalyst compounds being defined by the formulas: where ring B is either itself polycyclic, or ring B together with R is polycyclic. The catalysts of the invention are particularly effective in reductive amination procedures | 03-19-2015 |
Wen Tang, Middlesbrough GB
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20110043446 | COMPUTER INPUT DEVICE - Computer input apparatus comprising: an image capture device; and a marker member comprising at least two reference indicia, at least a first reference indicium being arranged to emit or reflect light having a first spectral characteristic, and at least a second reference indicium being arranged to emit or reflect light having a second spectral characteristic different from the first spectral characteristic, the image capture device being arranged to distinguish light of said first spectral characteristic from light of said second spectral characteristic thereby to distinguish the at least a first reference indicium from the at least a second reference indicium, the apparatus being configured to capture an image of the at least two reference indicia and to determine by means of said image a position and orientation of the marker member with respect to a reference frame. | 02-24-2011 |
Yiqing Tang, Surrey GB
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20080305176 | Process For Loading Polymer Particles With Drug - The present invention relates to processes for loading microsphere polymer particles with crystallisable drug, in the presence of a crystallisation inhibitor whereby crystallisation of the drug is inhibited. The invention is of particular value for loading polymer beads with paclitaxel, ibuprofen and/or dexamethasone. The polymer is suitably an anionic polyvinyl alcohol polymer. | 12-11-2008 |
20100119484 | DERIVATISATION OF BIOLOGICAL MOLECULES - The present disclosure relates to a new polymerisation process in which ethylenically unsaturated monomers are polymerised by a living radical polymerisation process in the presence of an initiator and a catalyst. Polymers produced by this new process are also thought to be novel and may be used to derivatise biological molecules to improve their efficacy as therapeutic treatments. A preferred polymer is of formula | 05-13-2010 |
20100160246 | MICROSPHERES FOR TREATMENT OF BRAIN TUMORS - There is provided a new use of microspheres comprising a water-insoluble, water-swellable polymer which is anionically charged at pH7, and electrostatically associated with the polymer, in releasable form, a cationically charged chemotherapeutic agent, in the manufacture of a composition for use in the treatment of a brain tumour, wherein in the treatment the composition is introduced into the brain and the chemotherapeutic agent is released from the microspheres, wherein the microspheres, when equilibrated in water at 37° C., comprise at least 40 wt % water based on weight of polymer plus water. Compositions comprising the microspheres and methods for the treatment of brain tumours are also provided. | 06-24-2010 |
20100166876 | LOADING OF HYDROPHOBIC DRUGS INTO HYDROPHILIC POLYMER DELIVERY SYSTEMS - A process is described for loading hydrophilic polymer particles with a water-insoluble solvent-soluble drug. The particles are preferably embolic agents. The method provides particles having little or no drug at the surface and in a surface layer, whereby the burst effect is minimised. The drug is precipitated in the core of the particle, leading to extended release. The drug is, for instance, paclitaxel, rapamycin, dexamethasone or ibuprofen. | 07-01-2010 |
20110229572 | DELIVERY OF DRUG COMBINATIONS - A composition comprising microspheres of a polymer matrix, having two different pharmaceutical actives having complementary, usually synergistic, activity in killing cells. The compositions have particular utility for treating tumours. Useful combinations are doxorubicin with rapamycin, irinotecan with ibuprofen, ibuprofen with doxorubicin and irinotecan with doxorubicin. The polymer matrix is preferably a crosslinked polyvinyl alcohol. The drugs may be included in the same microsphere, or microspheres each with an individual pharmaceutical agent may be mixed together. The microspheres are preferably used in chemoembolisation of tumours. | 09-22-2011 |
20110293731 | LOADING OF HYDROPHOBIC DRUGS INTO HYDROPHILIC POLYMER DELIVERY SYSTEMS - A process is described for loading hydrophilic polymer particles with a water-insoluble solvent-soluble drug. The particles are preferably embolic agents. The method provides particles having little or no drug at the surface and in a surface layer, whereby the burst effect is minimised. The drug is precipitated in the core of the particle, leading to extended release. The drug is, for instance, paclitaxel, rapamycin, dexamethasone or ibuprofen. | 12-01-2011 |
20120201867 | DRUG DELIVERY FROM EMBOLIC AGENTS - An embolic composition comprises microspheres formed of water-insoluble water-swellable anionic polymer having swollen diameter more than 100 μm, and a cationic camptothecin compound, preferably irinotecan. The microspheres are preferably formed of crosslinked polyvinylalcohol, preferably of ethylenically unsaturated polyvinylalcohol macromer, crosslinked with anionic ethylenically unsaturated anionic comonomer. The compositions are used to treat hypervascular tumours for instance colorectal metastases of the liver. | 08-09-2012 |
20120276151 | DRUG DELIVERY FROM EMBOLIC AGENTS - An embolic composition comprises microspheres formed of water-insoluble water-swellable anionic polymer having swollen diameter more than 100 μm and a cationic camptothecin compound, preferably irinotecan. The microspheres are preferably formed of crosslinked polyvinylalcohol, preferably of ethylenically unsaturated polyvinylalcohol macromer, crosslinked with anionic ethylenically unsaturated anionic comonomer. The compositions are used to treat hypervascular tumours for instance colorectal metastases of the liver. | 11-01-2012 |
20140030210 | DERIVATISATION OF BIOLOGICAL MOLECULES - The present disclosure relates to a new polymerisation process in which ethylenically unsaturated monomers are polymerised by a living radical polymerisation process in the presence of an initiator and a catalyst. Polymers produced by this new process are also thought to be novel and may be used to derivatise biological molecules to improve their efficacy as therapeutic treatments. A preferred polymer is of formula | 01-30-2014 |
20140162969 | MICROSPHERES FOR TREATMENT OF BRAIN TUMOURS - There is provided a new use of microspheres comprising a water-insoluble, water-swellable polymer which is anionically charged at pH7, and electrostatically associated with the polymer, in releasable form, a cationically charged chemotherapeutic agent, in the manufacture of a composition for use in the treatment of a brain tumour, wherein in the treatment the composition is introduced into the brain and the chemotherapeutic agent is released from the microspheres, wherein the microspheres, when equilibrated in water at 37° C., comprise at least 40 wt % water based on weight of polymer plus water. Compositions comprising the microspheres and methods for the treatment of brain tumours are also provided. | 06-12-2014 |
20150110722 | IMAGEABLE POLYMERS - The present invention relates to hydrogels comprising 1,2-diol or 1,3-diol groups acetalised with a radiopaque species of one or more covalently bound radiopaque halogens which are imageable during embolization therapy. The invention further relates to methods of making radiopaque polymers and radiopaque hydrogel microspheres to provide an imageable drug delivery system. | 04-23-2015 |
20160030602 | IMAGEABLE EMBOLIC MICROSPHERE - This invention concerns imageable, radiopaque embolic beads, which are particularly useful for monitoring embolization procedures. The beads comprise iodine containing compounds which are covalently incorporated into the polymer network of a preformed hydrogel bead. The beads are prepared by activating pre-formed hydrogel beads towards nucleophilic attack and then covalently attaching iodinated compounds into the polymer network. The radiopaque beads may be loaded with chemotherapeutic agents and used in methods of embolizing hyperplastic tissue or solid tumors. | 02-04-2016 |
Yiqing Tang, Farnham Surrey GB
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20160030602 | IMAGEABLE EMBOLIC MICROSPHERE - This invention concerns imageable, radiopaque embolic beads, which are particularly useful for monitoring embolization procedures. The beads comprise iodine containing compounds which are covalently incorporated into the polymer network of a preformed hydrogel bead. The beads are prepared by activating pre-formed hydrogel beads towards nucleophilic attack and then covalently attaching iodinated compounds into the polymer network. The radiopaque beads may be loaded with chemotherapeutic agents and used in methods of embolizing hyperplastic tissue or solid tumors. | 02-04-2016 |