Patent application number | Description | Published |
20090026365 | Instrument and Method for Tandem Time-of-Flight Mass Spectrometry - A novel instrument and method for TOF/TOF mass spectrometry is offered. A spiral trajectory time-of-flight mass spectrometer satisfies the spatial focusing conditions for the direction of flight and a direction orthogonal to the direction of flight whenever ions make a turn in the spiral trajectory. An ion gate for selecting precursor ions is placed in the spiral trajectory of the spiral trajectory time-of-flight mass spectrometer. Electric sectors are placed downstream of the ion gate. | 01-29-2009 |
20090121130 | Orthogonal Acceleration Time-of-Flight Mass Spectrometer - An orthogonal acceleration time-of-flight mass spectrometer has: an ion source for ionizing a sample; a conductive box into which the ions are introduced; ion acceleration device causing the ions to be accelerated in a pulsed manner in synchronism with a signal giving a starting point of measurement; and ion detector for detecting the ions in synchronism with the acceleration of the ions. The conductive box is provided with an ion injection port and an ion exit port. A lift voltage is applied to the conductive box. This voltage is switched in synchronism with the signal giving the starting point of the measurement. | 05-14-2009 |
20110220786 | Tandem Time-of-Flight Mass Spectrometer - A tandem time-of-flight (TOF) mass spectrometer is offered whose first mass analyzer is a TOF mass spectrometer having a flight distance smaller than the flight distance sufficient to impart a desired mass resolution to the first mass analyzer. When a mass spectrum is measured with the first mass analyzer, a reflectron field is activated. When precursor ions are selected by the first mass analyzer, the reflectron field is deactivated to permit ions to pass through without being reflected. | 09-15-2011 |
20120068062 | Method and Apparatus for Tandem Time-of-Flight Mass Spectrometry - Tandem time-of-flight mass spectrometry method and apparatus permits an ion gate to be time set optimally at all times if the instrumental conditions are modified. Delayed extraction conditions for the mass-to-charge ratios of plural reference substances and optimum values of the time for which the ion gate is opened are measured and stored in a data table. Delayed extraction conditions and opening time of the ion gate which optimize the mass resolution at the mass-to-charge ratio of the desired precursor ions are found based on values stored in the table. | 03-22-2012 |
20120085905 | Tandem Time-of-Flight Mass Spectrometer - A tandem time-of-flight mass spectrometer having enhanced duty cycle is offered. The inventive mass spectrometer has an ion storage means and a time-calculating means, in addition to the components of a normal tandem time-of-flight mass spectrometer. The time-calculating means finds the time between the instant at which precursor ions are ejected from the ion storage means and the instant at which the ions arrive at a position inside the orthogonal acceleration region where the ions pass into the following first TOF ion optical system at a maximum passage efficiency. The precursor ions are accelerated in a pulsed manner according to the instant at which the ions reach the position giving the maximum passage efficiency. | 04-12-2012 |
20120298855 | Apparatus and Method for Time-of-Flight Mass Spectrometry - A flight-of-time mass spectrometer and method of flight-of-time mass spectrometry. The spectrometer includes a storage portion, a parameter adjusting portion, a parameter setting portion, and a flight time measuring portion. The parameter adjusting portion calculates values of an adjustment parameter correlated with any specified m/z value based on an adjustment table. The parameter setting portion sets the delayed extraction parameters of the ion source based on the values of the adjustment parameters calculated by the parameter adjusting portion. | 11-29-2012 |
20130289892 | Time-of-Flight Mass Spectrometer and Data Compression Method Therefor - A data compression method for use by a flight-of-time mass spectrometer reduces the amount of digital data, which are converted from mass spectra by a digitizer, by thinning out their data points without reducing the amount of information over the whole range. The mass spectrometer has a data processing unit including data reduction means which reduces the number of data points of digital data delivered from the digitizer in response to an electrical signal indicative of ions based on a previously entered data table such that m/z regions partitioned by given flight times or given ink are set to have different numbers of data points. | 10-31-2013 |
20130306859 | Tandem Time-of-Flight Mass Spectrometer and Method of Mass Spectrometry Using the Same - A tandem time-of-flight mass spectrometer is offered which can perform MS/MS measurements efficiently without sample wastage by ingeniously combining flight time ranges required by precursor ions with measurement times actually taken to measure the precursor ions. The mass spectrometer has an array input means for causing the flight time ranges required by selected precursor ions and the actually taken measurement times in which the precursor ions are measured to be appropriately arrayed in a time-sequential manner such that the flight time ranges and measurement times do not overlap each other. | 11-21-2013 |
20140077076 | Time-of-Flight Mass Spectrometer and Method of Controlling Same - A flight-of-time mass spectrometer is offered which can provide a variable range of collisional energies that can be made wider than heretofore. Also, a method of controlling this spectrometer is offered. The spectrometer has an ion source, a first mass analyzer, an ion gate, a potential lift, a collisional cell, a second mass analyzer, a detector, and a potential control portion for controlling the potential on the potential lift. When the precursor ions selected by the ion gate enter the potential lift, the potential control portion sets the potential on the conductive box at V | 03-20-2014 |
20140166874 | Imaging Mass Spectrometer and Method of Controlling Same - An imaging mass spectrometer capable of reducing the dependence of the resolution of a projection image on mass is offered. Also, a method of controlling this spectrometer is offered. The imaging mass spectrometer includes: a plate on which a sample is placed; a lens system through which ions generated by irradiating the sample with laser light pass; an ion optical system for separating the ions according to flight time corresponding to mass-to-charge ratio; a detection system for measuring arrival positions and flight times of the ions passed through the ion optical system and generating an image of the sample when it is ionized; and a voltage control portion for sweeping the voltage applied to an electrode included in the lens system such that the lens effect of the lens system increases with time during a given period synchronized with the laser irradiation. | 06-19-2014 |