Patent application number | Description | Published |
20090315039 | Trench MOS type silicon carbide semiconductor device - A trench MOS type SiC semiconductor device includes a first conductivity semiconductor substrate, a first conductivity drift layer on the substrate, a second conductivity base layer on the drift layer, a first conductivity source layer on the base layer, a stripe shaped trench reaching from the surface of the source layer to the drift layer and having a gate electrode via a gate oxide film, a second conductivity layer on the bottom of the trench, and a second conductivity type region thereon on across-the-width side walls of at least one end of the trench, electrically coupling the second conductivity layer with the base layer. The device allows a low on-resistance without newly forming an electrode connected to the second conductivity layer even in the case of a device in which the second conductivity layer has to be grounded. | 12-24-2009 |
20100080794 | MUTANT POLYPEPTIDE HAVING EFFECTOR FUNCTION - Mutant polypeptides of the present invention contain an Fc region in which a cysteine residue is substituted for the second amino acid from the glycosylation site to the N terminal side in the Fc region. The Fc region is preferably a human IgG Fc region. The mutant polypeptides of the present invention may also contain an N-linked sugar chain at the glycosylation site in Fc region. Furthermore, a polypeptide domain other than the Fc region of the mutant polypeptides of the present invention may be a polypeptide molecule that recognizes a human cell surface molecule. | 04-01-2010 |
20100119997 | METHOD FOR PRODUCTION OF MESENCHYMAL CELL, METHOD FOR PRODUCTION OF TOOTH, AND MESENCHYMAL CELL FOR FORMATION OF TOOTH - The present invention provides a method for producing mesenchymal cells for production of mesenchymal cells for formation of a tooth, the method comprising: culturing totipotent stem cells in the presence of a differentiation inducer to produce a cell population after differentiation induction treatment, the cell population containing CD44-positive and CD29-positive cells or CD44-positive and CD 106-positive cells; and selecting, from the cell population after the differentiation induction treatment, the CD44-positive and CD29-positive cells or CD44-positive and CD 106-positive cells as the mesenchymal cells for the formation of the tooth. The present invention also provides a method for producing a tooth comprising: positioning, in a support carrier capable of retaining cells in a state of contacting therewith, a first cell mass substantially consisting of only either one of mesenchymal cells and epithelial cells and a second cell mass substantially consisting of only the other one of the mesenchymal cells and epithelial cells, the first and second cell masses being not mixed with each other but made to closely contact with each other; and culturing the first and second cell masses; wherein the mesenchymal cells comprise the mesenchymal cells for the formation of the tooth. | 05-13-2010 |
20110112103 | 5-HYDROXYPYRIMIDINE-4-CARBOXAMIDE COMPOUND - The present invention provides compounds which promote erythropoietin production. Compounds represented by the following general formula (1) or pharmacologically acceptable salts thereof are provided: | 05-12-2011 |
20110129917 | CELL ISOLATION METHOD - The present invention is a method for isolating a desired cell, which comprises selectively applying culture conditions including a culture medium to a sample potentially containing various cells, with addition of a cell enlarger simultaneously with, before or after the application. Thereby, it is possible to conveniently and efficiently obtain unknown but useful microorganisms occurring in a natural environment that are less competitive. | 06-02-2011 |
20110207159 | SCREENING METHOD FOR EFFICIENTLY OBTAINING USEFUL MICROBIAL STRAINS FROM MICROBIAL SAMPLE OBTAINED FROM NATURAL ENVIRONMENT AND REAGENT AND SCREENING KIT TO BE USED THEREFOR - A screening method for efficiently obtaining useful microbial strains from a sample comprises a first step of inoculating a culture medium with the sample potentially containing multiple microbial cells to culture the sample in the presence of a cell enlarger; a second step of introducing an esterase substrate fluorescent stain into the culture medium; a third step of isolating enlarged microbial cells stained in the second step according to a micromanipulation method to produce multiple culture media for establishment each inoculated with a single microbial cell; a fourth step of culturing the microbial cell in each of the culture media for establishment; and a fifth step of selecting culture media for establishment, in which cell proliferation has been confirmed, among the multiple culture media for establishment cultured in the fourth step. | 08-25-2011 |
20120220609 | 5-HYDROXYPYRIMIDINE-4-CARBOXAMIDE DERIVATIVE - The present invention provides a compound which enhances the production of erythropoietin. The present invention provides a compound represented by formula (1): | 08-30-2012 |
20130089827 | Methods For Manufacturing A Regenerated Tooth Unit - A method for manufacturing a regenerated tooth unit comprising a step of disposing and culturing a regenerated tooth germ inside a spacer in vivo in the body of a mammal is provided, wherein said spacer is configured so as to enable prevention of said regenerated tooth germ being extended to more than the maximum tolerance; and configured such that the regenerated tooth germ disposed inside is communicatable with the exterior of the spacer. | 04-11-2013 |
20130101951 | Method For Restoring Alveolar Bone Via Transplant of a Regenerated Tooth Unit - The object of the present invention is to provide a method for restoring the alveolar bone of a mammal with a missing tooth. | 04-25-2013 |
20140256027 | Perfusion Culture Method and Perfusion Culture Device for Organ or Tissue - Disclosed are a perfusion culture method and a perfusion culture device whereby a perfusate can be delivered to all parts of an organ or tissue so that the organ or tissue can be preserved while sufficiently maintaining the function thereof. Specifically disclosed is a method for perfusion culture of an organ or tissue removed from a mammal, said organ or tissue having been removed together with a second organ or tissue connected to the aforesaid organ or tissue in vivo, which comprises a step for fixing said second organ or tissue so as to hang the aforesaid organ or tissue and a step for perfusing blood vessels in the aforesaid organ or tissue with a perfusate. | 09-11-2014 |
20140356797 | DENTAL IMPLANT AND METHOD FOR PRODUCING SAME - The purpose of the present invention is to provide a dental implant which enables the formation of a functional periodontal tissue around the implant after the implantation of the implant. The dental implant according to the present invention is characterized in that a cell mass originated from a tooth germ tissue or a periodontal ligament tissue is placed on the surface of the implant and the surface of the implant on which the cell mass is to be placed is the whole or a part of a surface that is surrounded by an alveolar bone of a recipient during the implantation of the implant. | 12-04-2014 |