Patent application number | Description | Published |
20080249291 | Oligonucleotides Derived From Mycobacterium for Stimulating Immune Function, Treating Immune-Related Diseases, Atopic Dermatitis and/or Protecting Normal Immune Cell - Disclosed are oligonucleotides for manipulating an immune reaction. The oligonucleotides of the present invention may be useful to stimulate the immune function, to treat the immune-related diseases and the atopic dermatitis, or to protect the normal immune cells. | 10-09-2008 |
20080272424 | Nonvolatile Memory Device Having Fast Erase Speed And Improved Retention Characteristics And Method For Fabricating The Same - Disclosed herein is a nonvolatile memory device that includes a substrate, a tunneling layer over the substrate, a charge trapping layer over the tunneling layer, an insulating layer for improving retention characteristics over the charge trapping layer, a blocking layer over the insulating layer, and a control gate electrode over the blocking layer. Also disclosed herein is a method of making the device. | 11-06-2008 |
20080280830 | FUSION PROTEIN COMPRISING FK506 BINDING PROTEIN AND METHOD OF MAKING AND USING THE SAME - Disclosed is a fusion protein containing a FK506 binding protein and a cell-transducing domain. Also, disclosed is a method of making the fusion protein and use of the fusion protein in a pharmaceutical or cosmetic composition. The cell-transducing domain is, for example, a PEP-1. | 11-13-2008 |
20090062224 | Therapeutic use of cpg oligodeoxynucleotide for skin disease - Disclosed is the therapeutic use of CpG oligodeoxynucleotides for skin diseases. The CpG oligodeoxynucleotides (CpG ODNs) of the present invention show excellent immunoactive effects against skin diseases in both cases of CpG ODNs with a phosphorothioate backbone and CpG ODNs with a phosphodiester backbone. | 03-05-2009 |
20100025246 | APPARATUS AND METHOD FOR DETECTING MOTION CHARACTERISTICS OF PARTICLES IN FLOW CHANNEL - Disclosed herein is an apparatus and method for detecting the motion characteristics of particles in a flow channel. The apparatus of the present invention includes first and second electrode groups, each comprising a pair of electrodes, which are arranged to be spaced apart from each other in a flow channel, the pair of electrodes functioning as both a drive electrode and a sensing electrode for directly applying voltage and measuring impedance between the electrodes. An operation control unit measures variation in electrical pulses generated in the first and second electrode groups, thus detecting motion characteristics of the particles. The present invention is advantageous in that it does not require complicated optical measuring instruments or analyzing instruments, and in that it can be used to easily detect the motion characteristics of particles in a flow channel merely by analyzing variation in electrical pulses without requiring preliminary information. | 02-04-2010 |
20100165117 | METHOD AND APPARATUS FOR GENERATING COMPRESSED FILE, AND TERMINAL COMPRISING THE APPARATUS - An aspect of a method and apparatus for generating a compressed image file, and a terminal including the apparatus is receiving frame data comprising encoded image data of at least one frame of a raw image, generating first encoded thumbnail image data of the encoded image data, correcting the encoded image data and generating the compressed image file by using the corrected image data and the first encoded thumbnail image data when the encoded image data has an illuminance value lower than a preset reference value, and generating the compressed image file by using the encoded image data and the first encoded thumbnail image data when the encoded image data has an illuminance value greater than the preset reference value. | 07-01-2010 |
20100167343 | OVIDUCT SPECIFIC EXPRESSION PROMOTER AND RECOMBINANT EXPRESSION VECTOR COMPRISING THE SAME - An oviduct specific expression promoter and a recombinant expression vector including the same. A promoter of an AGR2 gene is expressed specifically in the chicken oviduct, and a recombinant expression vector includes the promoter and a desired gene for encoding a desired protein. The oviduct specific promoter and the recombinant expression vector including the promoter can induce the expression of a protein specifically in the oviduct, i.e., an organ that secrets proteins so as to accumulate with a large amount in the egg. Accordingly, the oviduct specific promoter and the recombinant expression vector of the present invention can be advantageously used to produce transformed chickens, which can massively yield useful elements of high added value, produce functional eggs, and improve the economic traits of the poultry. | 07-01-2010 |
20100168222 | NOVEL USE OF SARGACHROMENOL - The present invention relates to novel use of sargachromenol, and more particularly, the present invention relates to novel use of sargachromenol for destroying and/or lysing hyperproliferating keratinocyte. Accordingly, since sargachromenol of the present invention has activity in destroying and/or lysing keratinocyte, it may be useful for keratinocyte lysing agents in the skin area where the keratinocytes are hyperproliferating or peeling agents. | 07-01-2010 |
20100266568 | EC SOD AND USE THEREOF - The present invention relates to an EC SOD and the use thereof. More particularly, the present invention relates to an EC SOD and the use thereof for preventing or treating skin diseases, particularly dermatitis or psoriasis. | 10-21-2010 |
20100321045 | Device And System For Measuring Properties Of Cells And Method Of Measuring Properties Of Cells Using The Same - According to a device and system for measuring the properties of cells, there is an advantage in that, since a cell accommodation unit having a volume is provided, the properties of three-dimensional cells can be measured. Further, the present invention is advantageous in that it enables passive measurement of multiple properties which passively measures the electrical, mechanical and/or optical properties of cells, and active measurement of multiple properties which actively applies electrical, mechanical and optical types of stimulation to cells and measures their electrical, mechanical and/or optical reactions, thus measuring the multiple properties of cells with high reliability. | 12-23-2010 |
20100321450 | Droplet Receiver and Method Of Receiving Droplets - Disclosed herein is a droplet receiver. The droplet receiver includes an internal space formed such that its sectional area is reduced towards an input part, thus preventing the rebounding of droplets which enter a droplet receiving part, and includes an intercepting fluid layer so as to isolate the received droplets from the outside, thus preventing droplets received in the droplet receiving part from being contaminated and volatilizing. | 12-23-2010 |
20110028547 | NOVEL USE OF CAPSIATE OR DIHYDROCAPSIDATE - The present invention relates to a new use of capsiate or dihydrocapsiate, more particularly to a composition for preventing and treating inflammatory disease, angiogenesis-related disease and autoimmune disease or for suppressing immunity comprising capsiate, dihydrocapsiate or a pharmaceutically acceptable salt thereof as an effective ingredient. The composition and immunosuppressant of the present invention may be used for preventing and treating inflammatory disease, angiogenesis-related disease and autoimmune disease, and for suppressing immunity. | 02-03-2011 |
20110207807 | NEW USE FOR HOMOISOFLAVONE OR A SALT THEREOF - The present disclosure relates to a new use of homoisoflavanone or a salt thereof. More particularly, it relates to a pharmaceutical composition for the prevention and treatment of inflammatory diseases or allergic diseases comprising homoisoflavanone represented by Chemical Formula 1 or a salt thereof, a use of homoisoflavanone or a salt thereof in the manufacture of an agent for the preventing and treating of inflammatory diseases or allergic diseases, and a method for treating inflammatory diseases or allergic diseases including administering an effective dose of homoisoflavanone or a salt thereof to a subject in need thereof. | 08-25-2011 |
20120071424 | PHARMACEUTICAL COMPOSITION USED IN PROPHYLAXIS OR TREATMENT OF HYPERPROLIFERATIVE SKIN CONDITIONS AND MALIGNANT MELANOMAS COMPRISING PACHASTRISSAMINE AS ACTIVE INGREDIENT - Disclosed is a novel use of phytosphingosine. More particularly, disclosed are a composition for preventing or treating hyper-proliferative skin diseases comprising pachastrissamine as an active ingredient, a use of pachastrissamine or a pharmaceutically acceptable salt thereof for preparing a preventing/therapeutic agent of hyper-proliferative skin diseases, and a method for treating hyper-proliferative skin diseases administering an effective amount of pachastrissamine or a pharmaceutically acceptable salt thereof to a subject in need thereof. The pachastrissamine inhibits the degradation of FoxO3a protein and increases the expression of FoxO3a protein. Thus, the inventive pharmaceutical composition has a preventing of treating effect on hyper-proliferative diseases by inducing apoptosis of hyper-proliferative cells and inhibiting the cell cycle. Accordingly, the disclosed composition, a use, and the method can be used for preventing or treating various hyper-proliferative skin diseases such as skin cancer or psoriasis. | 03-22-2012 |
20120093796 | NOVEL USE OF EC-SOD AND METHOD FOR PREPARING THEREOF - The present invention relates to compositions for preventing or treating angiogenesis-mediated diseases or allergic diseases which contain, as an active ingredient, an EC-SOD protein or a vector having a polynucleotide encoding thereof. The EC-SOD protein or the vector having a polynucleotide encoding the EC-SOD protein has the effect on inhibiting angiogenesis by inhibiting the expression of VEGF and MMP-9 which induce angiogenesis. Therefore, the EC-SOD protein or the vector may be useful for preventing or treating angiogenesis-mediated diseases. And the EC-SOD protein or the vector having a polynucleotide encoding said EC-SOD protein also has the effect on inhibiting over-differentiation of Th2 cells which cause allergic diseases, inhibiting transcription factor (NF-κ B), and reducing degranulation of human mast cells. Accordingly, the EC-SOD protein or the vector may be useful for preventing or treating allergy diseases. In addition, the inventive method for preparing an EC-SOD protein may be used in preparing an EC-SOD protein having the activity on a large scale. Therefore, the inventive method may be useful industrially. | 04-19-2012 |
20120315694 | CELL CULTURE UNIT AND CELL CULTURE DEVICE INCLUDING THE SAME - There is provided a cell culture device, which includes a plurality of cell culture units, in which the cell culture unit includes: a cell culture tub that defines a culture space for cultivating cells, contains culture medium in the culture unit, and has an air layer above the culture medium; a drainage channel that is connected to the cell culture tub to discharge used culture medium to the integral drainage channel; an open culture medium reservoir that supplies new culture medium into the cell culture tub; and a droplet generator that is disposed between the cell culture tub and the open culture medium reservoir and supplies the culture medium from the open culture medium reservoir to the cell culture tub, using negative pressure of the air layer generated when the used culture medium is discharged. | 12-13-2012 |
20130137553 | WALKING TRAINING APPARATUS - Provided is a walking training apparatus including: a walking-assist robot which is worn on a lower half of a body of a walking trainee; a treadmill which has a tread plate moving at a predefined speed which the walking trainee walks on; a load pulling unit which holds a body of the walking trainee upward; and a controller which controls driving of the walking-assist robot, the treadmill, and the load pulling unit, wherein the load pulling unit includes: a harness which is worn on the body of the walking trainee; a main rope which is connected to the harness; a driving motor which operates to pull the main rope so as to pull the harness upward; and a counter-load weight plate unit which applies a counter-load to the walking trainee. Accordingly, the load pulling unit pulls a patient, and a counter-load is appropriately set according to a state of the patient or a purpose of a therapy, so that it is possible to prevent the patient from falling during the waling training, and it is possible to effectively perform rehabilitation training of the patient. | 05-30-2013 |
20130245117 | NOVEL USE OF CAPSIATE OR DIHYDROCAPSIDATE - The present invention relates to a new use of capsiate or dihydrocapsiate, more particularly to a composition for preventing and treating inflammatory disease, angiogenesis-related disease and autoimmune disease or for suppressing immunity comprising capsiate, dihydrocapsiate or a pharmaceutically acceptable salt thereof as an effective ingredient. The composition and immunosuppressant of the present invention may be used for preventing and treating inflammatory disease, angiogenesis-related disease and autoimmune disease, and for suppressing immunity. | 09-19-2013 |
20140335067 | NOVEL USE OF EC-SOD AND METHOD FOR PREPARING THEREOF - A method for treating a disease, particularly asthma and anaphylactic shock, comprises administering to a subject in need thereof an effective amount of an EC-SOD protein or a vector having a polynucleotide encoding thereof. | 11-13-2014 |
20140335068 | NOVEL USE OF EC-SOD FOR TREATING ANGIOGENESIS-MEDIATED EYE DISEASES - A method for treating an angiogenesis-mediated eye disease, includes administering to a subject in need thereof an effective amount of EC-SOD protein, or a vector having a polynucleotide encoding the EC-SOD protein, to treat angiogenesis-mediated eye diseases. | 11-13-2014 |
20140336135 | NOVEL USE OF RHODODENDRIN - The present invention relates to a novel use of rhododendrin, and more particularly to a composition for antioxidant purposes or for the prevention or treatment of hyperproliferative skin disorders, which comprises rhododendrin as an active ingredient; and a method for inhibiting reactive oxygen species or for preventing and treating a hyperproliferative skin disorder, which comprises administering an effective amount of rhododendrin to a subject in need thereof. Rhododendrin is not cytotoxic and has an excellent effect of eliminating a large amount of reactive oxygen species (ROS) generated by TNF-α/IFN-γ or UV light, and thus is effectively used to prepare an antioxidant cosmetic composition or an antioxidant food composition. In addition, rhododendrin has the effect of inhibiting skin cell hyperproliferation and has an excellent effect of inhibiting a hyperproliferative skin disorder or skin hyperkeratinization mediated by Toll-like receptors (TLRs) in various skin diseases, particularly psoriasis. | 11-13-2014 |
20140343150 | NOVEL PHYTOSPHINGOSINE DERIVATIVES, AND COMPOSITION COMPRISING SAME FOR PREVENTING AND TREATING INFLAMMATORY SKIN DISEASES, AUTOIMMUNE DISEASES, AND HYPERKERATOSIS DISEASES - A phytosphingosine derivative of chemical formula IA or IB, and a composition comprising the phytosphingosine derivative for preventing and treating inflammatory skin diseases, autoimmune diseases, and hyperkeratotic diseases. The phytosphingosine derivatives of the present disclosure are involved with transcription factors related to inflammation, autoimmune diseases and hyperkeratotic diseases, the expression and the generation of inflammatory mediators, signal transduction mechanisms, and the expression and the activity of relevant enzymes and the like. | 11-20-2014 |
20140357720 | NOVEL PHYTOSPHINGOSINE DERIVATIVES, AND A COSMETIC COMPOSITION COMPRISING THE SAME FOR PREVENTING AND AMELIORATING INFLAMMATORY SKIN DISEASES AND HYPERKERATOSIS DISEASES - A phytosphingosine derivatives of chemical formula IA or IB, and a cosmetic composition including the phytosphingosine derivative. The phytosphingosine derivatives are involved with transcription factors related to inflammation and hyperkeratotic diseases, the expression and the generation of inflammatory mediators, signal transduction mechanisms, and the expression and the activity of relevant enzymes and the like. | 12-04-2014 |