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Syed Ali

Syed Ali, North Andover, MA US

Patent application numberDescriptionPublished
20090105166Novel lapachone compounds and methods of use thereof - The present invention provides novel tricyclic spiro-oxathiine naphthoquinone derivatives, a synthetic method for making the derivatives, and the use of the derivatives to induce cell death and/or to inhibit proliferation of cancer or precancerous cells. The naphthoquinone derivatives of the present invention are related to the compound known as β-lapachone (3,4-dihydro-2,2-dimethyl-2H-naphtho(1,2-b)pyran-5,6-dione).04-23-2009
20090176801NOVEL LAPACHONE COMPOUNDS AND METHODS OF USE THEREOF - The invention provides lapachone analogs and derivatives as well as methods of use thereof. These compounds can be used in pharmaceutical compositions for the treatment or prevention of cell proliferation disorders. These compounds can also be used in the treatment or prevention of cancer or precancerous conditions.07-09-2009
20100183603Compositions and Methods for the Treatment of Cancer - The present invention relates to pyrrolidine-2,5-dione compounds, and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising pyrrolidine-2,5-dione compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a compound or pyrrolidine-2,5-dione compound of the present invention. (Ia) (Ib) (IIa) (IIIb) Where U is independently selected from: (I) or (II)07-22-2010
201003117541,4-Disubstituted Naphthalenes as Inhibitors of P38 Map Kinase - Naphthalene-based compounds having linked heterocyclic and aromatic rings capable of inhibiting P38, methods for inhibiting P38 in vivo or in vitro, diagnostics for determining activity in the treatment of P38 and/or cytokine-associated conditions and methods for treating conditions associated with P38 activity or cytokine activity; more particularly naphthalene-based compounds of Formula (I) having a morpholine heterocyclic ring, and methods of use thereof.12-09-2010
20110105470Novel Lapachone Compounds And Methods of Use Thereof - The present invention provides novel tricyclic spiro-oxathiine naphthoquinone derivatives, a synthetic method for making the derivatives, and the use of the derivatives to induce cell death and/or to inhibit proliferation of cancer or precancerous cells. The naphthoquinone derivatives of the present invention are related to the compound known as β-lapachone (3,4-dihydro-2,2-dimethyl-2H-naphtho(1,2-b)pyran-5,6-dione).05-05-2011
20110301160Inhibitors of P38 and Methods of Using the Same - In general, the present invention relates to compounds capable of inhibiting p38 in vivo or in vitro, and methods for treating conditions associated with p38 activity or cytokine activity.12-08-2011

Patent applications by Syed Ali, North Andover, MA US

Syed Ali, Atlanta, GA US

Patent application numberDescriptionPublished
20100317566COMPOSITIONS AND METHODS FOR TREATING AIDS OR CANCER BY INHIBITING THE SECRETION OF MICROPARTICLES - Novel peptides that inhibit the release of microparticles from cells are disclosed. The peptide contains at least one VGFPV motif at the N-terminal and has a length of 10-100 amino acids. Also disclosed is polynucleotide encoding the peptide, expression vectors carrying the polynucleotide, and methods for treating AIDS and tumors using the novel peptides.12-16-2010
20130018002COMPOSITIONS AND METHODS FOR TREATING AIDS OR CANCER BY INHIBITING THE SECRETION OF MICROPARTICLES - Novel peptides that inhibit the release of microparticles from cells are disclosed. The peptide contains at least one VGFPV motif at the N-terminal and has a length of 10-100 amino acids. Also disclosed is polynucleotide encoding the peptide, expression vectors carrying the polynucleotide, and methods for treating AIDS and tumors using the novel peptides.01-17-2013
20130018003COMPOSITIONS AND METHODS FOR TREATING AIDS OR CANCER BY INHIBITING THE SECRETION OF MICROPARTICLES - Novel peptides that inhibit the release of microparticles from cells are disclosed. The peptide contains at least one VGFPV motif at the N-terminal and has a length of 10-100 amino acids. Also disclosed is polynucleotide encoding the peptide, expression vectors carrying the polynucleotide, and methods for treating AIDS and tumors using the novel peptides.01-17-2013

Syed Ali, Houston, TX US

Patent application numberDescriptionPublished
20100073189MONOCONDUCTOR DATA-POWER TRANSMISSION - In some embodiments, apparatus and systems, as well as methods, may operate to acquire downhole data associated with a borehole casing, process a portion of the downhole data at a downhole location to provide processed data, regulate surface motor power received at a motor downhole, filter the surface motor power, and transmit the processed data to a surface location on a monoconductor that also carries the surface motor power. Additional apparatus, systems, and methods are disclosed.03-25-2010

Syed Ali, Romeoville, IL US

Patent application numberDescriptionPublished
20090096423METHOD AND SYSTEM FOR PULSE CHARGING AN AUTOMOTIVE BATTERY - A pulse charging profile for a vehicle battery is synchronized with driver or vehicle demanded current disturbances by phase tracking the fundamental frequency of the desired pulse charging profile to those driver or vehicle demanded current disturbances. When these driver or vehicle demanded disturbances are not active, the tracked charging profile is honored.04-16-2009

Syed Ali, Westborough, MA US

Patent application numberDescriptionPublished
20110142804NANOFIBER SCAFFOLD - The invention is directed to a device and method to prevent migration of Human Mesenchymal Stem Cells (hMSCs) from a delivery site while allowing communication between the stem cells and native cardiomyocytes. The device is characterized by scaffold pore size, fiber diameter and biomaterial selection. The invention includes a two part polyurethane scaffold that prevents migration of stem cells, allows gap junction formation through pores and is packaged for minimally invasive delivery.06-16-2011

Syed Ali, Pulau Pinang MY

Patent application numberDescriptionPublished
20130089525ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE THEREOF - The present application discloses a method for treating microbial infection using an antimicrobial composition comprises antimicrobial peptide which contains at least one VGFPV motif.04-11-2013