Patent application number | Description | Published |
20090043941 | System and method for allowing coexistence of multiple PCI managers in a PCI express system - A system and method that allows a plurality of SR-PCIMs to operate within a PCIe fabric. The system and method describe a master SR-PCIM election process and transfer of mastership from a master SR-PCIM to a standby SR-PCIM under certain conditions. The system and method leverage the PCI configuration space and PCI messages so that SR-PCIMs from multiple vendors can potentially interoperate. | 02-12-2009 |
20090248949 | System and Method for Increased System Availability In Virtualized Environments - A method is provided for managing errors in a virtualized information handling system that includes an error detection system and a hypervisor allowing multiple virtual machines to run on the information handling system. The hypervisor may assign at least one memory region to each of multiple virtual machines. The error detection system may detect an error, determine a physical memory address associated with the error, and report that address to the hypervisor. Additionally, the hypervisor may determine whether the memory region assigned to each virtual machine includes the physical memory address associated with the error. The hypervisor may shut down each virtual machine for which a memory region assigned to that virtual machine includes the physical memory address associated with the error, and not shut down each virtual machine for which the memory regions assigned to that virtual machine do not include the physical memory address associated with the error. | 10-01-2009 |
20100175064 | SYSTEM AND METHOD FOR RAW DEVICE MAPPING IN TRADITIONAL NAS SUBSYSTEMS - A method is provided for data storage management in a virtualized information handling system that includes a first and second network storage resource, a hypervisor allowing multiple virtual machines to run on the virtualized information handling system, and a data access agent. The data access agent may intercept a data access request initiated by a virtual machine and intended for the first network storage resource. In response to intercepting the data access request, the data access agent may establish a connection with the first network storage resource, and retrieve from the first network storage resource metadata associated with the data access request. The retrieved metadata may identify a location of the second network storage resource. Additionally, the data access may establish a connection with the second network storage resource using the location of the second network storage resource identified by the retrieved metadata. The virtual machine may complete the intercepted data access request via the established connection with the second network storage resource. | 07-08-2010 |
20120207155 | SYSTEM AND METHOD FOR SCALABLE, EFFICIENT, AND ROBUST SYSTEM MANAGEMENT COMMUNICATIONS VIA VENDOR DEFINED EXTENSIONS - In accordance with the present disclosure, a system and method for transmitting communications over a transmission medium between a first component and a second component is provided. The system and method may include an information handling system in which a packet is defined. The packet may include at least one header at a specific bit location and a vendor defined header extension, located in a packet payload portion of the packet. The system and method may further include at least one control command defined within the information handling system. The at least one control command may, for example, be used to negotiate the meaning of at least one field in the header. In addition, the at least one control command may be used to handle and recover from errors within communications and to control the flow of communications once transmission has commenced. | 08-16-2012 |
20120233508 | System and Method for Increased System Availability in Virtualized Environments - A method is provided for managing errors in a virtualized information handling system that includes an error detection system and a hypervisor allowing multiple virtual machines to run on the information handling system. The hypervisor may assign at least one memory region to each of multiple virtual machines. The error detection system may detect an error, determine a physical memory address associated with the error, and report that address to the hypervisor. Additionally, the hypervisor may determine whether the memory region assigned to each virtual machine includes the physical memory address associated with the error. The hypervisor may shut down each virtual machine for which a memory region assigned to that virtual machine includes the physical memory address associated with the error, and not shut down each virtual machine for which the memory regions assigned to that virtual machine do not include the physical memory address associated with the error. | 09-13-2012 |
20120239849 | SYSTEM AND METHOD FOR PERFORMING RAID I/O OPERATIONS IN PCIE-BASED STORAGE RESOURCES - Systems and methods for performing RAID I/O operations in PCIe-based storage resources are disclosed. In accordance with embodiments of the present disclosure, a method for performing a read operation may be provided. The method may include overlaying memory address space of storage resources of a source logical unit for the read operation onto a destination address. The method may also include determining whether the source logical unit is a RAIDO array. The method may additionally include generating a source address in a receive buffer for each storage resource of the source logical unit if the source logical unit is a RAIDO array. The method may further include storing data received from each storage address of the logical unit at the generated source address of the receive buffer associated with such storage resource. | 09-20-2012 |
20130007572 | System And Method For Look-Aside Parity Based Raid - Redundant storage of information is provided by distributing storage functions between a RAID controller and switching device. The switching device multi-casts writes to storage devices and to the RAID controller. The RAID controller generates parity for the information and writes the parity to the storage devices in space reserved for parity by the switching device. Information is read from the storage devices through the switching device without action by the RAID controller. | 01-03-2013 |
20130111161 | SYSTEM AND METHOD FOR RETENTION OF HISTORICAL DATA IN STORAGE RESOURCES | 05-02-2013 |
20130191833 | SYSTEM AND METHOD FOR ASSURING PERFORMANCE OF DATA SCRUBBING OPERATIONS - A method may include determining based on at least one data scrubbing parameter associated with at least one storage resource that the at least one storage resource is scheduled for a data scrubbing operation. The method may also include cause the at least one storage resource to transition from a low-power mode to a normal-power mode in order to perform a data scrubbing operation in response to a determination that the at least one storage resource is scheduled for a data scrubbing operation. The method may additionally include determining based on the at least one data scrubbing parameter that the data scrubbing operation is scheduled to cease. The method may further comprise causing the at least one storage resource to transition from the normal-power mode to the low-power mode in response to a determination that the data scrubbing operation is scheduled to cease. | 07-25-2013 |
Patent application number | Description | Published |
20100125055 | MUC-1 CYTOPLASMIC DOMAIN PEPTIDES AS INHIBITORS OF CANCER - The invention provides for peptides from the MUC1 cytoplasmic domain and methods of use therefor. These peptides can inhibit MUC1 oligomerization, thereby preventing tumor cell growth, inducing tumor cell apoptosis and necrosis of tumor tissue in vivo. | 05-20-2010 |
20110015138 | INHIBITION OF INFLAMMATION USING ANTAGONISTS OF MUC1 - The invention provides for peptides from the MUC1 cytoplasmic domain and methods of use therefor. These peptides can inhibit MUC1 oligomerization, inhibit the interaction of MUC1 with NF-κB or a STAT, and block inflammatory response mediated by NF-κB or STAT signaling. | 01-20-2011 |
20110251246 | SMALL MOLECULE INHIBITORS OF MUC1 AND METHODS OF IDENTIFYING THE SAME - The invention provides methods for the identification of small molecules that inhibit MUC1 oligomerization, and the functions flowing therefrom. In addition, small molecules that prevent MUC1 oligomerization are disclosed. Identified molecules will find use in treating a variety of MUC1-related inflammatory conditions, including MUC1-related cancers. | 10-13-2011 |
20120045502 | ANTAGONISTS OF MUC1 - The present invention is directed to improved compositions for cellular delivery of peptides. Using segments of only 3-5 positively-charged residues, one can effectively transfer peptides, including therapeutic peptides, into cells. Also provided are modified peptides such as those include stapled and cyclized peptide technology, as well as peptoids/peptidomimetics. | 02-23-2012 |
20120172312 | MUC-1 CYTOPLASMIC DOMAIN PEPTIDES AS INHIBITORS OF CANCER - The invention provides for peptides from the MUC1 cytoplasmic domain and methods of use therefor. These peptides can inhibit MUC1 oligomerization, thereby preventing tumor cell growth, inducing tumor cell apoptosis and necrosis of tumor tissue in vivo. | 07-05-2012 |
20130039974 | ANTI-MUC1 ANTIBODIES FOR CANCER DIAGNOSTICS - The present invention is directed to antibodies binding to the MUC1 cytoplasmic domain and methods of using such antibodies to treat, diagnose, detect and monitor cancers that express the MUC1 antigen. | 02-14-2013 |
20130101664 | MUC1 LIGAND TRAPS FOR USE IN TREATING CANCERS - The present invention is directed to improved compositions for the disruption of signaling through the external domain (ED) of MUC1, Ligand traps—molecules that include MUC1 ED sequences and immunoglobulin Fc domains—effectively “trap” molecules that interact with the native MUC1 ED. Given the involvement of MUC1 in a variety of disease states, disrupting the interaction of other molecules with MUC1 ED is useful in treating these disease, in particular cancer. | 04-25-2013 |
20130274198 | TREATING MUC1-EXPRESSING CANCERS WITH COMBINATION THERAPIES - The invention provides method of treating cancers that express MUC1 by the administration of PI3-K inhibitors in combination with MUC1-directed cancer therapies. The PI3-K inhibition may advantageously be combined with peptides that inhibit MUC1 oligomerization, or further with other standard anticancer therapies such as chemo-, radio- and surgical therapies. | 10-17-2013 |
20140187494 | INHIBITION OF INFLAMMATION USING ANTAGONISTS OF MUC1 - The invention provides for peptides from the MUC1 cytoplasmic domain and methods of use therefor. These peptides can inhibit MUC1 oligomerization, inhibit the interaction of MUC1 with NF-κB or a STAT, and block inflammatory response mediated by NF-κB or STAT signaling. | 07-03-2014 |
20140322332 | ANTAGONISTS OF MUC1 - The present invention is directed to improved compositions for cellular delivery of peptides. Using segments of only 3-5 positively-charged residues, one can effectively transfer peptides, including therapeutic peptides, into cells. Also provided are modified peptides such as those include stapled and cyclized peptide technology, as well as peptoids/peptidomimetics. | 10-30-2014 |