Patent application number | Description | Published |
20090028914 | MEDICAL DEVICES INCORPORATING COLLAGEN INHIBITORS - Provided herein are implantable or insertable biomedical devices comprising a substrate and a collagen inhibitor on or in said substrate, and methods of treatment using the same. In some embodiments, the device is an absorbable esophageal or tracheal stent. In some embodiments, the device is a vascular stent. Wound closure devices are also provided herein, including a substrate and a collagen inhibitor on or in the substrate. Also provided are surgical packings, including a substrate and a collagen inhibitor on or in the substrate. A barrier material for preventing adhesions in a subject is further provided, including a preformed or in situ formable barrier substrate and a collagen inhibitor on or in the substrate. An ointment comprising a collagen inhibitor is further provided. Kits comprising the coated substrates are also provided. | 01-29-2009 |
20140128416 | MEDICAL DEVICES INCORPORATING COLLAGEN INHIBITORS - Provided herein are implantable or insertable biomedical devices comprising a substrate and a collagen inhibitor on or in said substrate, and methods of treatment using the same. In some embodiments, the device is a urethral, ureteral, or nephroureteral catheter or stent. In some embodiments, the device is an absorbable esophageal or tracheal stent. Wound closure devices are also provided herein, including a substrate and a collagen inhibitor on or in the substrate. Also provided are surgical packings, including a substrate and a collagen inhibitor on or in the substrate. A barrier material for preventing adhesions in a subject is further provided, including a preformed or in situ formable barrier substrate and a collagen inhibitor on or in the substrate. Kits comprising the coated substrates are also provided. | 05-08-2014 |
Patent application number | Description | Published |
20110108507 | Sectional container with a detachable base and lid cover - A sectional liquid dispensing (lotions, creams, soaps, cleansers, etc.) container that includes a finger actuated pump assembly which extends a dip tube near the bottom of a container. The container has three individual components to form the complete assembly. The upper section of container has been designed to contain a tamper evident closure member; mold incorporated at its lower most edge. The lower section (base); containing a closure member mold incorporated onto its top edge, is designed to snap fit into upper section of container. The lower section is approximately one third the height of container or less. The lid cover snaps onto the bottom surface of the lower section, using the tamper evident closure member. The usage of these closures provide frangible edges for easy removal of locking tear bands; which allow for separation of components, while also providing evidence of any product tampering. When finger pump assembly fails to dispense the remaining liquids in the container; the bottom half of container is then detached to access liquids. The upper half of container and pump assembly can then be discarded. A lid cover is provided to protect remaining liquids from contamination and excess drying. The lid cover is designed to snap-fit onto the bottom edge and underneath the containers lower section. The present design provides for dual dispensing (two individual products) from one container when upper section has been modified into a separate enclosure. The usage of dual finger actuated pumps may be used. The sectional container allows consumers to regain usage of those liquids or creams otherwise lost. | 05-12-2011 |
20150021344 | SECTIONAL CONTAINER WITH A DETACHABLE BASE AND LID COVER - A sectional liquid dispensing (lotions, creams, soaps, cleansers, etc.) container that includes a finger actuated pump assembly which extends a dip tube near the bottom of a container. The container has three individual components to form the complete assembly. The upper section of container has been designed to contain a tamper evident closure member; mold incorporated at its lower most edge. The lower section (base); containing a closure member mold incorporated onto its top edge, is designed to snap fit into upper section of container. The lower section is approximately one third the height of container or less. The lid cover snaps onto the bottom surface of the lower section, using the tamper evident closure member. The usage of these closures provide frangible edges for easy removal of locking tear bands; which allow for separation of components, while also providing evidence of any product tampering. When finger pump assembly fails to dispense the remaining liquids in the container; the bottom half of container is then detached to access liquids. The upper half of container and pump assembly can then be discarded. A lid cover is provided to protect remaining liquids from contamination and excess drying. The lid cover is designed to snap-fit onto the bottom edge and underneath the containers lower section. The present design provides for dual dispensing (two individual products) from one container when upper section has been modified into a separate enclosure. The usage of dual finger actuated pumps may be used. The sectional container allows consumers to regain usage of those liquids or creams otherwise lost. | 01-22-2015 |
Patent application number | Description | Published |
20090141237 | Integrated Optical Coherence Imaging Systems for Use in Ophthalmic Applications and Related Methods and Computer Program Products - A system for imaging a sample is provided that includes an optical coherence tomography (OCT) portion having an associated OCT path. A second imaging portion is provided having an associated second image path, different from the OCT path. A fixation target having an associated fixation path, different from the second image path and the OCT path is also provided. The OCT path, the second image path and the fixation path are confocal at a common image plane. Related handheld systems are also provided. | 06-04-2009 |
20090231578 | MULTI-CHANNEL FIBER OPTIC SPECTROSCOPY SYSTEMS EMPLOYING INTEGRATED OPTICS MODULES - The invention provides unitary optics modules that integrate several light management functions for performing optical spectroscopy, such as Raman spectroscopy, and optical spectroscopy systems that include one or more of the unitary optics modules. Methods of using the modules and systems are also provided. | 09-17-2009 |
20100315592 | Optical Coherence Imaging Systems Having a Mechanism for Shifting Focus and Scanning Modality - Some embodiments of the present invention provide adapters for use in posterior imaging systems. The adapters include lens set configured to adapt the posterior imaging system to operate as an anterior imaging system. Related optical coherence tomography systems and anterior imaging systems are also provided herein. | 12-16-2010 |
20100321636 | Optical Coherence Imaging Systems Having a Mechanism for Shifting Focus and Scanning Modality and Related Adapters - Some embodiments of the present invention provide adapters for use in posterior imaging systems. The adapters include lens set configured to adapt the posterior imaging system to operate as an anterior imaging system. Related optical coherence tomography systems and anterior imaging systems are also provided herein. | 12-23-2010 |
20120140176 | Optical Coherence Imaging Systems Having a Mechanism for Shifting Focus and Scanning Modality - Some embodiments of the present invention provide adapters for use in posterior imaging systems. The adapters include lens set configured to adapt the posterior imaging system to operate as an anterior imaging system. Related optical coherence tomography systems and anterior imaging systems are also provided herein. | 06-07-2012 |
20120176615 | MULTI-PATH SPECTROMETER - A spectrometer in accordance with the present disclosure may provide multiple optical paths from the inputs to the camera, where the paths are as nearly identical as possible. For example, a spectrometer in accordance with the present disclosure may include multiple inputs, input optics, a diffraction grating, output optics, and a camera. The multiple inputs may be imaged onto different sections of the camera using the same input optics, the same diffraction grating, and the same output optics. | 07-12-2012 |
20120262720 | OPTICAL COHERENCE TOMOGRAPHY IMAGING SYSTEM - An optical coherence tomography (OCT) imaging system is disclosed. In an embodiment of the invention, an OCT imaging system may include (a) multiple scan geometries, including a lateral scan of a beam perpendicular to the scan direction and a rotating scan where the beam is perpendicular to a curved surface (such as the front of the eye), and (b) a low coherence interferometry engine based on spectral domain interferometry, with a spectrometer capable of ultra deep imaging. | 10-18-2012 |
20130169971 | OCT IMAGING SYSTEM FOR CURVED SAMPLES - This patent specification describes an OCT imaging system that implements at least one of the following: (1) adjusting the path length of a reference arm during an OCT scan of a curved sample or between OCT scans; (2) adjusting the focus of a scanning beam as the scanning beam moves across the curved sample during the OCT scan or between OCT scans; (3) adjusting polarization control during the OCT scan or between OCT scans; and/or (4) changing dispersion compensation across the OCT scan or between OCT scans. | 07-04-2013 |
Patent application number | Description | Published |
20080226729 | STABLE POWDER FORMULATIONS OF ALUM-ADSORBED VACCINES - The present invention is directed to methods for preparing a stable powder formulation of an alum-adsorbed vaccine. The methods comprise atomizing a liquid formulation comprising an immunogen adsorbed onto an aluminum adjuvant to produce an atomized formulation, freezing the atomized formulation to produce frozen particles, and drying the frozen particles to produce dried powder particles. Pharmaceutical compositions comprising a stable powder formulation of an alum-adsorbed vaccine are also disclosed herein. The pharmaceutical compositions are stable at high temperatures and can be reconstituted in a pharmaceutically acceptable carrier to produce a reconstituted liquid vaccine that exhibits little or no particle agglomeration and retains immunogenicity. Methods of using the alum-adsorbed vaccine compositions for preventing and treating a disease in a subject, wherein the disease is associated with the particular immunogen, are further provided. | 09-18-2008 |
20110159047 | STABLE POWDER FORMULATIONS OF ALUM-ADSORBED VACCINES - The present invention is directed to methods for preparing a stable powder formulation of an alum-adsorbed vaccine. The methods comprise atomizing a liquid formulation comprising an immunogen adsorbed onto an aluminum adjuvant to produce an atomized formulation, freezing the atomized formulation to produce frozen particles, and drying the frozen particles to produce dried powder particles. Pharmaceutical compositions comprising a stable powder formulation of an alum-adsorbed vaccine are also disclosed herein. The pharmaceutical compositions are stable at high temperatures and can be reconstituted in a pharmaceutically acceptable carrier to produce a reconstituted liquid vaccine that exhibits little or no particle agglomeration and retains immunogenicity. Methods of using the alum-adsorbed vaccine compositions for preventing and treating a disease in a subject, wherein the disease is associated with the particular immunogen, are further provided. | 06-30-2011 |
20110251546 | MEDICAMENT MICRODEVICE DELIVERY SYSTEM, CARTRIDGE AND METHOD OF USE - A method and device for intradermal delivery of a reconstituted medicament. The device includes a chamber, which is in fluid communication with a microdevice, e.g. microabrader or one or more microneedles. A cartridge containing the medicament may be located within said chamber. At least one burstable membrane retains a medicament within the housing. The method involves the steps of positioning the device at a delivery site on the skin of a patient and intradermally administering the medicament by dispensing a diluent from a diluent source an through inlet port to rupture the membranes, reconstitute the medicament and deliver the reconstituted medicament through the microdevice to the dermal region of the skin. | 10-13-2011 |
20110270223 | Reconstituting Infusion Device - A system and method for a patch-like, self-contained multi-component substance infusion device which provides one or more substantially hidden patient needles which can be placed in fluid communication with a fluid reservoir assembly that includes a rigid bladder portion used in conjunction with a non-distensible bladder film, such as a metallized film. The device can be attached to a skin surface via an adhesive contact and a pressurization system provides a pressure to the contents of a fluid reservoir assembly. Improvements to dry powdered formulations for reconstitution for preferred use in the device are also disclosed. | 11-03-2011 |
20110276021 | Reconstituting Infusion Device - A system and method for a patch-like, self-contained multi-component substance infusion device which provides one or more substantially hidden patient needles which can be placed in fluid communication with a fluid reservoir assembly that includes a rigid bladder portion used in conjunction with a non-distensible bladder film, such as a metallized film. The device can be attached to a skin surface via an adhesive contact and a pressurization system provides a pressure to the contents of a fluid reservoir assembly. Improvements to dry powdered formulations for reconstitution for preferred use in the device are also disclosed. | 11-10-2011 |
20110319814 | Reconstituting Infusion Device - A system and method for a patch-like, self-contained multi-component substance infusion device which provides one or more substantially hidden patient needles which can be placed in fluid communication with a fluid reservoir assembly that includes a rigid bladder portion used in conjunction with a non-distensible bladder film, such as a metallized film. The device can be attached to a skin surface via an adhesive contact and a pressurization system provides a pressure to the contents of a fluid reservoir assembly. Improvements to dry powdered formulations for reconstitution for preferred use in the device are also disclosed. | 12-29-2011 |
20140107613 | SYSTEM AND METHOD FOR DETECTING OCCLUSIONS IN A MEDICATION INFUSION SYSTEM USING PULSEWISE PRESSURE SIGNALS - A medical fluid communication system is disclosed comprising a pump controller and a fluid detector. The fluid detector detects characteristics of the fluid and provides fluid measurements to the pump controller, which detects if the fluid is flowing in the medication delivery system. In the event fluid is not flowing due to an occlusion, the pump controller may attempt to resolve the occlusion or may provide a warning to a user that an occlusion is occurring. | 04-17-2014 |
20150258272 | Reconstituting Infusion Device - A system and method for a patch-like, self-contained multi-component substance infusion device which provides one or more substantially hidden patient needles which can be placed in fluid communication with a fluid reservoir assembly that includes a rigid bladder portion used in conjunction with a non-distensible bladder film, such as a metallized film. The device can be attached to a skin surface via an adhesive contact and a pressurization system provides a pressure to the contents of a fluid reservoir assembly. Improvements to dry powdered formulations for reconstitution for preferred use in the device are also disclosed. | 09-17-2015 |
20150314071 | Valve Permitting Mixing in a Drug Delivery Device | 11-05-2015 |
Patent application number | Description | Published |
20140096354 | SERVICE APPARATUS FOR TURBOMACHINE - Various embodiments include a service apparatus for a turbomachine. The service apparatus can include: a frame for coupling to an opening in the turbomachine; a bridge member operably coupled to the frame and spanning a width of the frame, the bridge member being substantially movable along a length of the frame; and a crane member operably coupled to the bridge member, the crane member being substantially movable along the width of the frame, wherein the crane member includes at least one attachment device for attaching to an object within the turbomachine. | 04-10-2014 |
20140165359 | TURBINE TRANSITION PIECE ALIGNMENT APPARATUS AND METHOD - Various embodiments include alignment systems for turbines. In various particular embodiments, an apparatus for aligning an end of a transition piece (TP) with an outlet of a combustor component is disclosed. The apparatus can include: a mount configured to attach to the combustor component proximate the outlet; a hinge component pivotably connected to the mount, the hinge component having an axis of motion substantially perpendicular with a primary axis of the combustor component; a dummy transition piece (dummy TP) component fixedly attached to the hinge component for pivoting with the hinge component; and an adjustment apparatus having a first end fixedly attached to the dummy TP, and a second end with an actuatable adjustment member for modifying a position of the dummy TP. | 06-19-2014 |
20140165397 | TURBINE TRANSITION PIECE (TP) APPARATUS AND METHOD - Various embodiments include an apparatus for installing or removing a transition piece (TP) in a gas turbine. The apparatus can include: a control arm assembly sized to rest within an opening in the gas turbine; a guide system coupled to the control arm assembly, the guide system for transporting the TP within the opening in the gas turbine; and a counter balance coupled to the guide system, the counter balance for countering weight of the TP during the installing or the removing of the TP in the gas turbine. | 06-19-2014 |
20150144761 | APPARATUS AND SYSTEM FOR POSITIONING OF EQUIPMENT - Embodiments of the present disclosure include apparatuses and systems used for the positioning of equipment. An apparatus according to an embodiment of the present disclosure can include a height adjustable table; a platform coupled to the height adjustable table; a tilt adjuster coupled to the platform, the tilt adjuster being configured to tilt the platform relative to the height adjustable table; an equipment support structure slidably connected to the platform, the equipment support structure being configured to support a piece of equipment; a drive mechanism coupled to the platform and configured to slidably move the equipment support structure across the platform; and a bracket coupled to the equipment support structure, wherein the bracket is configured to removably attach the piece of equipment. | 05-28-2015 |
20150260043 | REMOVAL DEVICE - A tool for removing a component from a turbomachine is provided. The tool includes a body having an alignment portion and a connection portion. The alignment portion defines a longitudinal axis and a cross sectional shape complementary to a slot defined in a rotor wheel of the turbomachine. When the tool is positioned in the slot, the connection portion is configured to contact the component. The tool additionally includes a force section connected to the body and configured to transfer a force to the connection portion in a direction substantially parallel to the longitudinal axis of the alignment portion. | 09-17-2015 |
20150328728 | TURBOMACHINE BUCKET DISPLACEMENT APPARATUS AND METHOD OF USE - Various embodiments include apparatuses adapted to displace turbomachine components from a location within a turbomachine. In some embodiments apparatuses for displacing a turbine bucket from a turbomachine wheel slot include a body having at least two contacting portions for contacting the turbomachine wheel, a linear actuator coupled to the body, and an engagement arm for engaging the turbine bucket, the engagement arm coupled to the linear actuator and adapted to be actuated in a first axial direction by the linear actuator. | 11-19-2015 |
20150328729 | TURBOMACHINE COMPONENT DISPLACEMENT APPARATUS AND METHOD OF USE - Various embodiments include apparatuses adapted to displace components from a location within a turbomachine. In some embodiments an apparatus for displacing a component of a gas turbine from a first slot in a spacer disk includes a body including a mounting member configured to affixedly attach to a second slot of the spacer disk, a linear actuator coupled to the body and a displacement arm coupled to the linear actuator, the displacement arm actuatable in a first axial direction by the linear actuator to contact the component and displace the component relative to the first slot. | 11-19-2015 |