Patent application number | Description | Published |
20090275616 | STRAIGHTFORWARD ENTRY TO 7-AZABICYCLO[2.2.1]HEPTANE-1-CARBONITRILES AND SUBSEQUENT SYNTHESIS OF EPIBATIDINE ANALOGUES - The present invention relates to a group of substituted-7-azabicyclo-[2.2.1]heptyl derivatives with biological activity. The present invention also relates to synthetic methods for producing said substituted-7-azabicyclo-[2.2.1]heptyl derivatives. The present invention also relates to certain intermediates for producing such substituted-7-azabicyclo-[2.2.1]heptyl derivatives, as well as a synthetic method for producing such intermediates. The present invention also relates to pharmaceutical compositions comprising such substituted-7-azabicyclo-[2.2.1]heptyl derivatives, as well as their use as medicaments for the treatment of diseases mediated by a Nicotinic Acetylcholine Receptor or a receptor being a member of the Neurotransmitter-gated Ion Channel Superfamily, such as pain, Alzheimer's disease, Parkinson's disease, schizophrenia, epilepsy and nicotine addiction. | 11-05-2009 |
20100093807 | SUBSTITUTED 7-AZABICYCLO[2.2.1]HEPTYL DERIVATIVES USEFUL FOR MAKING PHARMACEUTICAL COMPOSITIONS - This invention provides 1-substituted-7-azabicyclo[2.2.1]heptyl derivatives, intermediates and methods for producing them, which are therapeutic agents useful for the prevention and treatment of central nervous system disorders and diseases mediated by a Nicotinic Acetylcholine Receptor such as Alzheimer's disease, Parkinson's disease, schizophrenia, epilepsy, pain, nicotine addiction and dementia. | 04-15-2010 |
20120245196 | 1-SUBSTITUTED 2-AZABICYCLO [3.1.1] HEPTYL DERIVATIVES USEFUL AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS FOR TREATING NEUROLOGIC DISORDERS - This invention provides 2-azabicyclo[3.1.1]heptyl derivatives, and methods for producing them, which are useful therapeutic agents for preventing or treating central nervous system disorders and disease mediated by a Nicotinic Acetylcholine Receptor such as, but not limited to, Alzheimer's disease, Parkinson's disease, schizophrenia, epilepsy, dementia, pain and nicotine addiction. | 09-27-2012 |
20150014169 | ELECTROCHEMICAL PROCESSES TO SEPARATE PRODUCTS DERIVED FROM BIOLOGICAL CONVERSIONS - The disclosure relates to efficient methods of controlling biological conversions while simultaneously removing and converting some of the generated products. More specifically, and, for example, the disclosure discloses electrochemical processes to remove and capture potentially toxic ammonium during anaerobic digestions and to remove and capture carboxylic acids during bioethanol production. The disclosure can, thus, be used to enhance bioproduction processes via controlling pH and/or reduction/oxidation, in combination with in situ product recovery. | 01-15-2015 |
Patent application number | Description | Published |
20090012108 | SALT OF 4-[[4-[[4-(2-CYANOETHENYL)-2,6-DIMETHYLPHENYL]AMINO]-2-PYRIMIDINYL]AMINO]BENZONITRILE - The present invention relates to a pharmaceutical composition comprising as active ingredient the hydrochloric acid salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethyl-phenyl]amino]-2-pyrimidinyl]amino]benzonitrile and to processes for their preparation. | 01-08-2009 |
20090215804 | FUMARATE OF 4- [[4- [[4- (2-CYANOETHENYL) -2,6-DIMETHYLPHENYL)AMINO] -2-PYRIMIDINYL]AMINO]BENZONITRILE - The present invention relates to the fumarate salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile, pharmaceutical compositions comprising as active ingredient said salt and to processes for their preparation. | 08-27-2009 |
20110008434 | SALT OF 4-[[4-[[4-(2-CYANOETHENYL)-2,6-DIMETHYLPHENYL]AMINO]-2-PYRIMIDINYL- ]AMINO]BENZONITRILE - The present invention relates to a pharmaceutical composition comprising as active ingredient the hydrochloric acid salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethyl-phenyl]amino]-2-pyrimidinyl]amino]benzonitrile and to processes for their preparation. | 01-13-2011 |
20110150996 | SALT OF 4-[[4-[[4-(2-CYANOETHENYL)-2,6-DIMETHYLPHENYL]AMINO] -2-PYRIMIDINYL]AMINO]BENZONITRILE - The present invention relates to the fumarate salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile, pharmaceutical compositions comprising as active ingredient said salt and to processes for their preparation. | 06-23-2011 |
Patent application number | Description | Published |
20090143119 | RETRACTABLE ANTENNA STRUCTURE FOR USE IN TELECOMMUNICATIONS DEVICE - The invention relates to a retractable antenna structure for use in a telecommunications device. The antenna structure comprising a slide portion adapted for movably mounting the antenna structure in a cavity of a telecommunications device, such that the antenna structure is retractable into the cavity for storage and extensible from the cavity for operation, and an antenna portion carrying a flat radiation element for establishing at least one wireless network connection. The antenna portion comprises a first wing carrying a first part of the radiation element and a second wing carrying a second part of the radiation element. The wings are pivotally connected to each other between a storage position in which the wings lie on top of each other and an operational position in which the wings are spaced apart. The antenna portion further comprises at least one resilient member acting on at least one of the wings for spacing the wings apart. The invention further relates to a telecommunications device equipped with the antenna structure, such as a PCMCIA telecommunications card or a laptop computer | 06-04-2009 |
20130183841 | USB STICK WITH HINGEDLY MOUNTED USB CONNECTOR - The invention relates to a USB stick comprising an oblong body which comprises electronic components and a USB connector electrically connected to the electronic components, the oblong body comprising a first part and a second part which are fixed to each other by means of a hinge connection, the first part comprising the USB connector and being rotatable with respect to the second part between a storage position in which the USB connector is stored inside the oblong body and a first use position in which the USB connector extends from the oblong body, the hinge mechanism comprising a spring mechanism for moving the first part. The electronic components are included in the second part of the oblong body and the USB connector is connected through to the second part by means of a connecting cable at the hinge connection. | 07-18-2013 |
20130217248 | USB STICK WITH HINGEDLY MOUNTED USB CONNECTOR, ROTATABLE TO MULTIPLE USE POSITIONS - The invention relates to a USB stick comprising an oblong body which comprises electronic components and a USB connector electrically connected to the electronic components, the oblong body comprising a first part and a second part which are fixed to each other by means of a hinge connection, the first part comprising the USB connector and being rotatable with respect to the second part between a storage position in which the USB connector is stored inside the oblong body and a first use position in which the USB connector extends from the oblong body, the hinge mechanism comprising a spring mechanism for moving the first part. The hinge connection comprises a blocking mechanism, provided for releasably blocking the first part in the first use position or a second use position located between the first use position and the storage position. | 08-22-2013 |