Steven Charles
Steven Charles Defina, Burlingame, CA US
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20090156576 | Azetidines as MEK Inhibitors for the Treatment of Proliferative Diseases - Disclosed are compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof. Such compounds are MEK inhibitors and are useful in the treatment of proliferative diseases, such as cancer. Also disclosed are pharmaceutical compositions containing such compounds as well as methods of using the compounds and compositions of the invention in the treatment of cancer. | 06-18-2009 |
20090163471 | Tropane compounds - A compound according to Formula I or II: | 06-25-2009 |
20100249096 | Azetidines as MEK Inhibitors for the Treatment of Proliferative Diseases - Disclosed are compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof. Such compounds are MEK inhibitors and are useful in the treatment of proliferative diseases, such as cancer. Also disclosed are pharmaceutical compositions containing such compounds as well as methods of using the compounds and compositions of the invention in the treatment of cancer. | 09-30-2010 |
20100298290 | Benzoxazepines as Inhibitors of PI3K/mTOR and Methods of Their Use and Manufacture - The invention is directed to Compounds of Formula I: | 11-25-2010 |
20110071145 | Raf Modulators And Methods Of Use - The present invention relates to compounds of the Formula I, wherein G, A, X1, X2, X3, Z, E, Y, and X are defined herein. The compounds modulate protein kinase enzymatic activity to modulate cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. Compounds of the invention inhibit, regulate and/or modulate kinases, particularly Raf. Methods of using and preparing the compounds, and pharmaceutical compositions thereof, to treat kinase-dependent diseases and conditions are also an aspect of the invention. | 03-24-2011 |
20110263558 | Azetidines as MEK Inhibitors for the Treatment of Proliferative Diseases - Disclosed are compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof. Such compounds are MEK inhibitors and are useful in the treatment of proliferative diseases, such as cancer. Also disclosed are pharmaceutical compositions containing such compounds as well as methods of using the compounds and compositions of the invention in the treatment of cancer. | 10-27-2011 |
Steven Charles Defina, Oakland, CA US
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20140275527 | Azetidines as MEK Inhibitors for the Treatment of Proliferative Diseases - Disclosed are compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof. Such compounds are MEK inhibitors and are useful in the treatment of proliferative diseases, such as cancer. Also disclosed are pharmaceutical compositions containing such compounds as well as methods of using the compounds and compositions of the invention in the treatment of cancer. | 09-18-2014 |
20150141399 | MEK Inhibitors And Methods Of Their Use - Disclosed are compounds of Formula I: | 05-21-2015 |
Steven Charles Furlong, Sr., Maple Grove, MN US
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20100188001 | LED WHITE-LIGHT DEVICES FOR DIRECT FORM, FIT, AND FUNCTION REPLACEMENT OF EXISTING FLUORESCENT LIGHTING DEVICES - A white light LED-based lighting device configured for direct form, fit, and function replacement of existing incandescent and fluorescent devices is provided. The white light LED-based lighting device comprises a group of solid state light emitting diodes, electronics to activate the light emitting diodes, and an encapsulating housing configured for direct form, fit, and function replacement of existing fluorescent devices. | 07-29-2010 |
Steven Charles Garcia, South Riding, VA US
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20150112758 | ENHANCED DATA COLLECTION AND ANALYSIS - A method and corresponding apparatus that is configured to receive data from a mobile operator, process the data by, at least, anonymizing and aggregating the data to identify at least one market opportunity within a predefined market footprint, and generate a report that highlights the at least one market opportunity. | 04-23-2015 |
20150339686 | ENHANCED DATA COLLECTION, PROCESSING, AND ANALYSIS - A method and corresponding apparatus that is configured to receive data from a data producer (such as for example a telecommunications provider like a mobile operator); process (e.g., analyze, aggregate, etc.) the received data; and supply aspects of the results of the processing to a data consumer through for example an array of user interfaces. | 11-26-2015 |
Steven Charles Grossnickle, North Saanich CA
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20100297771 | METHOD OF EX VITRO SOWING, GERMINATION, GROWTH AND CONVERSION OF PLANT SOMATIC EMBRYOS OR GERMINANTS, AND NUTRIENT MEDIUM USED THEREFOR - A method of sowing a somatic plant embryo or germinant of a conifer species to facilitate subsequent development of the embryo or germinant into an autotrophic seedling. The method involves the following steps carried out ex vitro in non-sterile conditions: providing a nutrient medium comprising particles of a solid component present within a flowable or semi-solid component containing water and a carbohydrate nutrient for the embryo or germinant, dispensing a quantity of the nutrient medium onto a surface of a porous solid growth substrate for the somatic plant embryo or germinant, to and contacting the plant embryo or germinant with the nutrient medium. The nutrient medium has a fluidity such that at least some of the flowable or semi-solid component containing the carbohydrate nutrient remains in contact with the embryo or germinant at least until the embryo or germinant establishes vigorous growth under environmental conditions effective for such growth. The particles of the solid component are adapted to remain in contact with the embryo or germinant after of the flowable or semi-solid material dissipates, thereby providing continuing physical support for the embryo or germinant after the dissipation. The invention also relates to seedlings produced in this way and to the nutrient solution. | 11-25-2010 |
Steven Charles Kaishian, Wauwatosa, WI US
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20130273786 | ELECTRICAL POWER STAB SYSTEM AND METHOD FOR MAKING SAME - A power stab fork system is provided for power stab systems. The system comprises stab forks made of a steel layer bonded to a layer of highly conductive material such that the highly conductive material effectively conducts power with stabs while the steel layer keeps the stab fork in robust contact with the stab because of its stronger material properties. The stab forks may comprise a plurality of fingers for making independent contacts points onto a stab. Some embodiments included stab forks with one forked end, two forked ends, straight fingers, curved fingers, separated stab forks, conjoined stab forks, and so forth. | 10-17-2013 |
20140326420 | STRETCHED ARTIST CANVAS WITH RIGID FOAM BACK - A stretched artist canvas frame system is supported with a rigid foam back to either allow artists to apply pressure to a canvas without stretching it and causing sagging, or to allow artists to use the stretched artist canvas as an alternative for artists who paint on board. The frame system is a light weight alternative to painting on board, especially when the paintings become very large. The frame system provides the texture of canvas but the stiffness of a board by supporting the board with a lightweight rigid extruded foam. The frame system gives the artist the choice of painting on canvas or the feel of painting on board. The rigid foam back allows the artist to even create a smooth board finish if they choose through priming techniques. As the canvas gets larger, they do not get prohibitively heavier. | 11-06-2014 |
Steven Charles Leisher, San Diego, CA US
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20150363885 | TECHNIQUES AND SYSTEMS FOR MANAGING INVESTMENT AND INSURANCE POLICIES - Methods, systems, and devices are disclosed for managing investment and insurance policies. In one aspect, a method for managing a life insurance policy includes receiving information associated with a permanent life insurance policy and its policy holder, analyzing the information to generate a rating value of the permanent life insurance policy, and determining if the rating value is above a minimum threshold value to admit the permanent life insurance policy into a policy optimization portfolio. The method can also include creating financial value of the policy optimization portfolio by obtaining investment funding from a financial institution based on a cash value of the admitted permanent life insurance policies, investing at least some of the investment funding in one or more financial markets to receive a financial return, and determining a distribution of the financial return to provide to the policy holder and the financial institution. | 12-17-2015 |
Steven Charles Loechel, Frederiksberg DE
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20100317654 | 1,4-DIAZA-BICYCLO[3.2.2]NONYL OXADIAZOLYL DERIVATIVES AND THEIR MEDICAL USE - This invention relates to novel 1,4-diaza-bicyclo[3.2.2]nonyl oxadiazolyl derivatives and their use in the manufacture of pharmaceutical compositions. The compounds of the invention are found to be cholinergic ligands at the nicotinic acetylcholine receptors. | 12-16-2010 |
Steven Charles Machiorlette, Houston, TX US
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20100296685 | ADAPTER AND ELECTRONIC DEVICES FOR RECESSED LIGHT SOCKET - An adaptive use of recessed lights cans for retrofitting various types of light fixtures. For example, a recessed light could be retrofitted as a junction box. In other embodiments, the recessed light could supply power for a speaker that includes a threaded power. Other electronic devices are contemplated that could be installed in a recessed light housing, including a battery backup light, a wireless repeater, a surveillance camera, a cellular phone booster, an infrared repeater, a fan, a wireless perimeter barrier, an alarm system, a sound machine, a web cam, an electronic pest control, a smoke detector, a carbon monoxide detector, an air purifier, a HVAC repeater control, a temperature monitor, a humidity monitor, a sound monitor, a photoelectric motion detector light, a photoelectric light sensor, and a hanging mobile. | 11-25-2010 |
Steven Charles Mcilvenna, Calgary CA
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20100095615 | Ceiling attachment for full-height panel - A prefabricated wall panel has a top frame structure defining an upward-opening channel extending lengthwise along the upper edge of the panel. An elongate header member is normally disposed within this channel. The header member is vertically slidably supported on supports fixed to the top frame structure so that the header member, in a storage position, is retained in the space. When the panel has been swung upwardly so that the upper edge is aligned below a preinstalled ceiling track, then the header member is manually displaced upwardly until the header telescopes over the ceiling track. A fixed connection is then formed between the header and the ceiling track to provide lateral stability at the upper edge of the wall panel. | 04-22-2010 |
Steven Charles Poulakos, Zurich CH
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20150348273 | DEPTH MODIFICATION FOR DISPLAY APPLICATIONS - Techniques of depth modification for display applications are disclosed. A multiscopic video frame, including at least first and second images depicting a scene, is received. Depth information pertaining to the multiscopic video frame is received. A depth mapping function is determined based on one or more image characteristics of the multiscopic video frame, other than depth. The depth information is modified based on the depth mapping function. At least a third image is generated based on the modified depth information and based further on at least one of the first and second images, where the third image is output for display. | 12-03-2015 |
Steven Charles Quarre, Woodinville, WA US
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20090277292 | Precision drive mechanism for long-travel microscopy stage - It is a goal of the proposed invention to provide “encoder-like” performance without incurring the cost and complexity of a closed loop system. | 11-12-2009 |
Steven Charles Quarre, City Of Woodinville, WA US
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20110194175 | METHOD AND SYSTEM FOR FAST THREE-DIMENSIONAL STRUCTURED-ILLUMINATION-MICROSCOPY IMAGING - Embodiments of the present invention are directed to providing and controlling illumination for three-dimensional structured illumination microscopy. Three phase-coherent beams, referred to as a “beam triplet,” are produced with planar beamsplitters. The relative phases of the beams are controlled by piezo-coupled mirrors or other means. The beams pass through the microscope objective and interfere to produce the 3D structured illumination pattern. The spatial orientation and location of the pattern is manipulated by adjusting the relative phases of the beams. | 08-11-2011 |
Steven Charles Radlinger, Madison, WI US
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20100273464 | System for multimedia content-assisted trigger location, and service methods thereof - Disclosed is a mobile marketing and advertising based system comprised of a database, a mobile device, a trigger location (primary physical location), a secondary location in a favorable proximity to the trigger location and a means for providing multimedia content from the database to the mobile device. | 10-28-2010 |
Steven Charles Salimando, Little Silver, NJ US
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20140143801 | METHOD AND APPARATUS FOR COMMUNICATING EMERGENCY INFORMATION - A method that incorporates teachings of the subject disclosure may include, for example transmitting, by a system comprising a processor, via a first emergency media channel a first video stream comprising first evacuation routing information for a first evacuation group responsive to receiving a notification of an emergency event, instructing, by the system, a first media processor device to select the first emergency media channel while disabling selection of other media channels according to the first evacuation routing information, where the content of the emergency media channel is presented at a display device by way of the first media processor device, and enabling, by the system, the first media processor device to select the other media channels responsive to receiving user input acknowledging the emergency media channel. Other embodiments are disclosed. | 05-22-2014 |
20150237413 | METHOD AND APPARATUS FOR COMMUNICATING EMERGENCY INFORMATION - A method that incorporates teachings of the subject disclosure may include, for example transmitting, by a system comprising a processor, via a first emergency media channel a first video stream comprising first evacuation routing information for a first evacuation group responsive to receiving a notification of an emergency event, instructing, by the system, a first media processor device to select the first emergency media channel while disabling selection of other media channels according to the first evacuation routing information, where the content of the emergency media channel is presented at a display device by way of the first media processor device, and enabling, by the system, the first media processor device to select the other media channels responsive to receiving user input acknowledging the emergency media channel. Other embodiments are disclosed. | 08-20-2015 |
Steven Charles Schapel, Akron, OH US
Steven Charles Siessman, San Diego, CA US
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20090150200 | System and method for generating interpreted damage estimates information - A method and system for generating interpreted damage estimate information. The steps of generating an interpretation of repair operations consists of selecting a interpretation template from a plurality of interpretation templates, reading a damage estimate file, identifying one or more nomenclature in said damage estimate containing repair operations, determining the sections or groups' contained in said damage estimate file, identifying common section indices for the identified sections or groups, retrieving repair/refinish/replacement parts interpretations that consist of a common section index, related repair/refinish/replacement interpretation, interpreted section header, associated graphical images, and creating a displayable repair interpretation file. | 06-11-2009 |
Steven Charles Stegman, Eindhoven NL
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20140283832 | CUSHION WITH SELECTIVELY VARIABLE SOFTNESS/STIFFNESS - A cushion ( | 09-25-2014 |
Steven Charles Walko, Clifton Park, NY US
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20120118177 | METHOD AND APPARATUS FOR COMPRESSION OF LAMINATION STACK FOR A DYNAMOELECTRIC MACHINE - A method and apparatus is provided for compressing the lamination stack for a dynamoelectric machine. The apparatus includes a plurality of weight distribution plates and a plurality of pressing plates. The plurality of weight distribution plates are placed on one end of the lamination stack of the dynamoelectric machine. The plurality of pressing plates are placed on the plurality of weight distribution plates. A compressive force is applied to the lamination stack via the plurality of weight distribution plates and the plurality of pressing plates. | 05-17-2012 |
20120118178 | METHOD AND APPARATUS FOR COMPRESSION OF LAMINATION STACK FOR A DYNAMOELECTRIC MACHINE - A method and apparatus are provided for compression of a lamination stack for a dynamoelectric machine. The apparatus includes a plurality of hanger brackets attached to a face frame, a plurality of force application tubes secured to the brackets, a plurality of force applying rams located beneath the force application tubes, a plurality of pressing plates located beneath the force applying rams, and a plurality of weight distribution plates located beneath the pressing plates. A compressive force is applied to the lamination stack by the force applying rams via the pressing plates and weight distribution plates. | 05-17-2012 |
Steven Charles Werkheiser, Bear, DE US
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20130281589 | THERMOPLASTIC POLYAMIDE COMPOSITION - Disclosed is a thermoplastic polyamide composition including a) a polyamide resin; b) one or more polyhydric alcohols; c) one or more anti-whitening agents selected from the group consisting of poly(ethylene glycol), poly(ethylene glycol) diesters, poly(propylene glycol), poly(propylene glycol) diesters; and styrene-isoprene-styrene block copolymers; and mixtures of these; d) a lubricant; e) one or more reinforcement agents; and, optionally, f) a polymeric toughener comprising a reactive functional group and/or a metal salt of a carboxylic acid. | 10-24-2013 |
Steven Charles Zoz, Dunlap, IL US
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20130019819 | COOLANT CIRCUIT FOR ENGINE WITH BYPASS LINE - A coolant circuit for cooling of an engine in a power system. The coolant circuit includes an inlet line and an outlet line. The coolant circuit further includes a heat exchanger with a plurality of heat exchanging elements. The coolant circuit also includes a bypass line disposed in parallel to the heat exchanger, between the inlet line and the outlet line. A control valve is disposed in the coolant circuit regulating the flow of a coolant, such that the coolant flows through the heat exchanger and the bypass line when the control valve is in a fully open position. | 01-24-2013 |