Patent application number | Description | Published |
20080269105 | Delivery of drugs - Formulations of drugs and crystalline side chain polymers to provide controlled and/or sustained release drug formulations. | 10-30-2008 |
20090209558 | Polymer formulations for delivery of bioactive materials - Delivery of drugs in association with PLGA polymers which have crystallinity resulting from the presence of long chain alkyl groups in terminal units. | 08-20-2009 |
20090252777 | Method for formulating a controlled-release pharmaceutical formulation - Methods for making formulations of drugs and crystalline side chain polymers which formulations provide controlled and/or sustained release drug formulations. | 10-08-2009 |
20090263346 | Systems and methods for delivery of drugs - Systems and methods for delivering drugs. Crystalline polymeric systems, referred to as CYC carriers, are associated with the drugs, through chemical bonding or through physical association. The crystallinity of the CYC carriers results from the presence of crystallizable side chains, for example long chain n-alkyl moieties, which results in relatively low and sharp melting temperatures. One class of CYC carriers, referred to as CYSC polymers, have a majority of the crystallizable side chains pendant from the polymer backbone. Another class of CYC carriers, referred to as ECC polymers, have a majority of the crystallizable side chains attached to terminal units of the polymer backbone. The ECC polymers can for example be obtained by modification of PLGA polymers. The CYC carriers in another class are non-polymeric. Some CYC carriers, referred to as CYC assemblies, have enhanced crystallinity as a result of the physical association of crystallizable moieties which are present in different types of molecule, for example between a polymer containing crystallizable moieties and a monomer containing crystallizable moieties. Preferably the CYC carrier is bioerodable. | 10-22-2009 |
20100210792 | DRUG DELIVERY - Formulations of drugs and crystalline side chain polymers to provide controlled and/or sustained release drug formulations. | 08-19-2010 |
20110009571 | SYSTEMS AND METHODS FOR DELIVERY OF MATERIALS - Systems and methods for delivering release materials, for example drugs and other bioactive materials. Crystalline polymeric systems, referred to as CYC carriers, are associated with the release materials, through chemical bonding or through physical association. The crystallinity of the CYC carriers results from the presence of crystallizable side chains, for example long chain n-alkyl moieties, which results in relatively low and sharp melting temperatures. One class of CYC carriers, referred to as CYSC polymers, have a majority of the crystallizable side chains pendant from the polymer backbone. Another class of CYC carriers referred to as ECC polymers, have a majority of the crystallizable side chains attached to terminal units of the polymer backbone. The ECC polymers can for example be obtained by modification of PLGA polymers. The CYC carriers in another class of non-polymeric. Some CYC carriers, referred to as CYC assemblies, have enhanced crystallinity as a result of the physical association of crystallizable moieties which are present in different types of molecule, for example between a polymer containing crystallizable moieties and a monomer containing crystallizable moieties. For some uses, particularly the delivery of drugs, a bioerodable CYC carrier is preferably used. | 01-13-2011 |
20120088659 | Compositions and Methods for Delivery of Materials - Compositions for the controlled delivery of active ingredients, for example, drugs, cosmetic materials, and agricultural materials. The compositions include a multiplicity of particles, each of the particles comprising (1) a microstructure comprising a semicrystalline polymer which has a peak melting temperature, Tp, of at least 20° C., and (2) the active ingredient. The microstructure comprises
| 04-12-2012 |
20120142581 | Polymer Formulations for Delivery of Bioactive Materials - PLGA, PLA and PGA polymers which have crystallinity resulting from the presence of long chain alkyl groups in terminal units. The polymers are particularly useful for drug delivery. | 06-07-2012 |