Stephen Williams
Stephen Williams, Aberdeenshire GB
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20100104569 | HUMANIZED ANTIBODIES TO INTERFERON ALPHA RECEPTOR-1 (IFNAR-1) - Humanized monoclonal antibodies which bind to IFNAR-1, and related antibody-based compositions and molecules, are disclosed. Also disclosed are pharmaceutical compositions comprising the humanized antibodies and therapeutic and diagnostic methods for using the humanized antibodies. | 04-29-2010 |
20110086422 | HUMANIZED ANTIBODIES TO INTERFERON ALPHA RECEPTOR-1 (IFNAR-1) - Humanized monoclonal antibodies which bind to IFNAR-1, and related antibody-based compositions and molecules, are disclosed. Also disclosed are pharmaceutical compositions comprising the humanized antibodies and therapeutic and diagnostic methods for using the humanized antibodies. | 04-14-2011 |
20120183545 | CD20-Binding Polypeptide Compositions and Methods - A method of treating an autoimmune disease comprising administering to a patient a therapeutically effective amount of a CD20-binding polypeptide composition comprising a combination of a modified heavy chain variable region polypeptide and a modified light chain variable region polypeptide. The combination can be (a) a modified 2B8 antibody heavy chain variable region polypeptide of SEQ ID NO: 48; and a modified 2B8 antibody light chain variable region polypeptide of SEQ ID NO: 49; or (b) a modified Leu16 antibody heavy chain variable region polypeptide of SEQ ID NO: 50; and a modified Leu16 antibody light chain variable region polypeptide of SEQ ID NO: 51. | 07-19-2012 |
Stephen Williams, Port Coquitlam CA
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20100284290 | CONTEXT BASED DATA MEDIATION - A communication environment includes of one or more subscriber terminals capable of receiving and transmitting data over a communication network via a communication management system. The communication management system receives mobile communication device context information and mobile communication device identification information from the mobile communication device. The communication management system then identifies data availability profiles reflective of a prior determination of mobile communication device availability to receive data communications according to context. The communication management system then implements data filtering rules corresponding to a current data availability profile. | 11-11-2010 |
20130294340 | CONTEXT BASED DATA MEDIATION - A communication environment includes of one or more subscriber terminals capable of receiving and transmitting data over a communication network via a communication management system. The communication management system receives mobile communication device context information and mobile communication device identification information from the mobile communication device. The communication management system then identifies data availability profiles reflective of a prior determination of mobile communication device availability to receive data communications according to context. The communication management system then implements data filtering rules corresponding to a current data availability profile. | 11-07-2013 |
Stephen Williams, Montpelier, VT US
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20090062423 | ORTHOPAEDIC CEMENT MIXTURES WITH LOW WEIGHT PERCENT POLYVINYL ALCOHOL (PVA) SOLUTION - Orthopaedic bone cement mixtures include a primary material that has a flowable state and a solid mass state and a low weight percent amount of polyvinyl alcohol (PVA) material. The PVA material is distributed in the primary material. | 03-05-2009 |
20100198235 | SURGICAL SUTURE PASSER AND METHOD FOR PASSING SUTURE - A suture placement system that serves as both an open or endoscopic surgical repair means wherein tissue defects can be externally ligated in close opposition by the steps of: passing a sharp penetrating needle through tissue, wherein the sharp penetrating needle carries a suture near the distal end of the needle; capturing a portion of the suture with a snare that is mounted to an axially and rotationally mobile armature that is carried by the needle; and withdrawing a portion of the suture which has been passed through the tissue which is to be repaired. And a suture placement system that serves as both an open or endoscopic surgical repair means wherein tissue defects can be externally ligated in close opposition by the steps of: passing a sharp penetrating needle comprising a shaft and handle through tissue, wherein the sharp penetrating needle carries a suture snare near the distal end of the needle; positioning a suture adjacent to the suture snare using a cannula that is mounted to an axially and rotationally mobile armature that is carried by the needle; capturing a portion of the suture with the suture snare; and withdrawing a portion of the suture through the tissue which is to be repaired. | 08-05-2010 |
Stephen Williams, Bristol GB
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20090209129 | AIRCRAFT WIRING INSTALLATION - An aircraft wiring installation connecting a set of fuel side wires in an aircraft fuel tank to a set of airside wires outside the fuel tank, the installation comprising: a connector box having a fuel side wall ( | 08-20-2009 |
20120211607 | COMPOSITE STRUCTURE - A composite structure has first and second sections, and a curved corner joining the first and second sections. The structure includes a stack of fibre-reinforced plies. First and second external plies run from the first section into the second section round an inside and an outside of the corner, respectively. First and second internal plies are sandwiched between the first and second external plies, and run from the first section into the second section round the corner. The first internal fly is dropped off inside the second section. The second internal ply is dropped off inside the first section. The structure has an increased thickness where the first and second internal plies overlap. | 08-23-2012 |
20120213640 | COMPOSITE STRUCTURE - A composite structure has a first section, a second section, and a curved corner joining the first and second sections. The structure has a stack of fibre-reinforced plies including first and second external plies which run from the first section into the second section on an inside and an outside of the corner, respectively. A discontinuous first internal ply is sandwiched between the first and second external plies so that more of the first internal ply is located within the first section than within the second section. A second internal ply is sandwiched between the first and second external plies. The fibres of the first internal ply run at an angle θ to the fibres of the second internal ply. In some embodiments the angle θ is greater than 3° but less than 20°. In one embodiment the angle θ is between 35° and 42°. | 08-23-2012 |
20130302172 | SPACE FRAME STRUCTURE - A structure comprising a space frame including a plurality of strut sections which cross at one or more locations within the space frame to define a node at each respective crossing location, wherein the strut sections are laminates comprising a plurality of ply layers, and wherein the ply layers of the crossing strut sections are interleaved at the node(s). Also a method of forming the structure. Also An aerofoil structure, comprising a space frame defining a cage adapted to receive upper and lower covers so as to form upper and lower aerodynamic surfaces of the aerofoil, and at least one spar extending generally spanwise across the structure, wherein the spar includes a spar web and upper and lower spar caps, and wherein the spar web is disposed on one of an interior or exterior side of the cage, and the spar caps are attached to the other of the interior or exterior side of the cage. | 11-14-2013 |
Stephen Williams, Hilliard, OH US
Stephen Williams, Alford GB
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20090022738 | Multispecific deimmunized CD3-binders - The present invention provides a cytotoxically active CD3 specific binding construct comprising a first domain specifically binding to human CD3 and an Ig-derived second binding domain. Furthermore, a nucleic acid sequence encoding a CD3 specific binding construct of the invention is provided. Further aspects of the invention are vectors and host cells comprising said nucleic acid sequence, a process for the production of the construct of the invention and composition comprising said construct. The invention also provides the use of said constructs for the preparation of pharmacutical compositions for the treatment of particular diseases, a method for the treatment of particular diseases and a kit comprising the binding construct of the invention. | 01-22-2009 |
20130224205 | MULTISPECIFIC DEIMMUNIZED CD3-BINDERS - The present invention provides a cytotoxically active CD3 specific binding construct comprising a first domain specifically binding to human CD3 and an Ig-derived second binding domain. Furthermore, a nucleic acid sequence encoding a CD3 specific binding construct of the invention is provided. Further aspects of the invention are vectors and host cells comprising said nucleic acid sequence, a process for the production of the construct of the invention and composition comprising said construct. The invention also provides the use of said constructs for the preparation of pharmaceutical compositions for the treatment of particular diseases, a method for the treatment of particular diseases and a kit comprising the binding construct of the invention. | 08-29-2013 |
Stephen Williams, Newport GB
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20110147522 | METHOD OF STIFFENING A RIB - A method of stiffening a rib ( | 06-23-2011 |
Stephen Williams, Morgan Hill, CA US
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20110149443 | TUNABLE MICROSTRIP TRANSMISSION PATH IN A HARD DISK DRIVE - A disk pack, comprising at least one hard disk, is rotatably mounted to a housing. The disk pack defines an axis of rotation and a radial direction relative to the axis. At least one actuator mounted to the housing is coupled with a suspension and is movable relative to the disk pack. A slider, comprising a slider body and a head configured to read data from and write data to at least one hard disk, is coupled with the suspension. A first suspension electrical interconnect is configured to electrically couple a first signal conducting pathway with the slider and with a first non-terminated signal pathway. A second suspension electrical interconnect is configured to electrically couple a second signal conducting pathway with the slider and with a second non-terminated signal pathway. The length of the second non-terminated signal pathway is selected to achieve a desired impedance level. | 06-23-2011 |
20140168813 | MASS BALANCED FLEXURE GIMBAL FOR HEAD GIMBAL ASSEMBLY SWAY MODE CONTROL - Approaches to a mass balanced flexure gimbal assembly for controlling the sway mode of the loadbeam portion of the suspension of a head gimbal assembly (HGA) of a hard-disk drive (HDD). The sway mode of concern is that which is excited when a head slider is actuated by a plurality of piezo actuation devices of a secondary actuation system. A suspension includes a mass attached to the suspension flexure and configured for balancing a moment force about the gimbal, about which a slider rotates when microactuated. The mass is located on the side of the slider opposing the side on which the piezo actuation devices are mounted, to counteract the mass of the piezo devices. | 06-19-2014 |
Stephen Williams, Manchester GB
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20110167178 | Method and Apparatus for SATA Hot Unplug - A method and apparatus are provided for serial advanced technology attachment (SATA) hot unplug. In one embodiment, a method includes detecting a connection of a SATA storage device to a SATA host interface by monitoring physical (PHY) layer signals derived from SATA communication terminals, by a controller of the host interface. The detection being based on phase locked loop (PLL) response of the PHY layer signals. The method further includes detecting disconnection of the SATA device based on the PLL response and outputting a notification, by the controller, when the PLL response indicates that the SATA device has been disconnected. | 07-07-2011 |
Stephen Williams, Waunakee, WI US
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20120196524 | SYSTEM AND METHODS FOR ACTIVELY CONTROLLING AN HVAC SYSTEM BASED ON AIR CLEANING REQUIREMENTS - An active air cleaning controller is connected to a forced air heating, ventilation and air conditioning (HVAC) system. The active air cleaning controller uses call signals from a thermostat to the HVAC system and/or sensor signals to determine when, and for how long, the blower of the HVAC system has been active and whether to independently activate the blower. The active air cleaning controller uses at least the collected information regarding the blower run time to determine when to activate the blower, in addition to its use within the HVAC system, to cycle and thus clean the air in a living environment independently of call signals used to activate heating and/or cooling functions of the HVAC system. | 08-02-2012 |
Stephen Williams, Filton GB
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20140084516 | CURE TOOL - The invention provides a cure tool | 03-27-2014 |
Stephen Williams, Ebbw Vale GB
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20130129526 | WRINKLE CONTROL METHOD AND TOOL THEREFOR - A method for forming a laminate component, the method comprising the steps of: a) providing a tool having a moulding surface; b) arranging a stack of ply layers on the moulding surface of the tool; and c) moulding the stack of ply layers over the moulding surface in a moulding process, wherein the tool has a wrinkle control feature in its moulding surface for managing the development of wrinkle in the ply layers during the moulding process, and wherein the wrinkle control feature cooperates with the stack of ply layers during the moulding process to produce a local surface undulation in a nominal surface of the laminate component nearest the tool to either prevent wrinkling in the ply layers or initiate wrinkling in one or more of the ply layers at a predetermined location. Also, a tool having a wrinkle control feature, and a laminate component so formed. | 05-23-2013 |
20150283766 | WRINKLE CONTROL METHOD AND TOOL THEREFOR - A method for forming a laminate component, the method comprising the steps of: a) providing a tool having a moulding surface; b) arranging a stack of ply layers on the moulding surface of the tool; and c) moulding the stack of ply layers over the moulding surface in a moulding process, wherein the tool has a wrinkle control feature in its moulding surface for managing the development of wrinkle in the ply layers during the moulding process, and wherein the wrinkle control feature cooperates with the stack of ply layers during the moulding process to produce a local surface undulation in a nominal surface of the laminate component nearest the tool to either prevent wrinkling in the ply layers or initiate wrinkling in one or more of the ply layers at a predetermined location. Also, a tool having a wrinkle control feature, and a laminate component so formed. | 10-08-2015 |
Stephen Williams, County Dublin IE
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20140236167 | PNEUMOPERITONEUM DEVICE - A method for performing a laparoscopic procedure may include inserting a bag through an opening. The method may also include delivering tissue into the bag, sealing the bag, and inflating the bag to create an artificial pneumoperitoneum that extends the abdomen and provides additional working and viewing space. Further, the method may include carrying out a procedure on the tissue located in the inflated bag. | 08-21-2014 |
20140236168 | PNEUMOPERITONEUM DEVICE - A method for performing a laparoscopic procedure may include inserting a bag through an opening. The method may also include delivering tissue into the bag, sealing the bag, and inflating the bag to create an artificial pneumoperitoneum that extends the abdomen and provides additional working and viewing space. Further, the method may include carrying out a procedure on the tissue located in the inflated bag. | 08-21-2014 |
20150201922 | PNEUMOPERITONEUM DEVICE - A method for performing a laparoscopic procedure may include inserting a bag through an opening. The method may also include delivering tissue into the bag, sealing the bag, and inflating the bag to create an artificial pneumoperitoneum that extends the abdomen and provides additional working and viewing space. Further, the method may include carrying out a procedure on the tissue located in the inflated bag. | 07-23-2015 |
Stephen Williams, Stroud GB
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20150345228 | Drill Bit - A drill bit comprises at least one blade, comprising a plurality of cutting elements in the form of polycrystalline diamond cutters disposed on a leading edge of the blade, at least one diamond impregnated cutting region, disposed behind the leading edge of the blade, and wherein at least one of the cutters disposed on the leading, edge is an off-tip cutting element, arranged so that it does not engage with the formation during drilling until bit wear has taken place. | 12-03-2015 |
Stephen Williams, Franklin, WI US
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20160118795 | Distributed Energy Storage System and Method of Distributing Energy - This patent describes embodiments of systems, apparatus and methods to provide improved control and coordination of a multiplicity of electric distribution grid-connected, energy storage units deployed over a geographically-dispersed area. | 04-28-2016 |