Inventors list |
Assignees list |
Classification tree browser |
Top 100 Inventors |
Top 100 Assignees |
Stephen R.
Stephen R. Brych, Simi Valley, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100056765 | Formulations That Inhibit Protein Aggregation - Disclosed is a stable pharmaceutically acceptable formulation containing a pharmaceutically acceptable amount of a protein. Also disclosed are methods for preparing such formulations and methods for inhibiting protein aggregate formation induced by physical stresses associated with processing, manufacture, shipping, and storing protein formulations, particularly freeze/thaw stress. | 03-04-2010 |
Stephen R. Byrn, West Lafayette, IN US
| Patent application number | Description | Published |
|---|---|---|
| 20110130429 | PYRIDINES FOR TREATING INJURED MAMMALIAN NERVE TISSUE - Embodiments of the present disclosure provide a novel pyridine, pharmaceutical compositions comprising such pyridine, and the use of such compositions in treating injured mammalian nerve tissue, including but not limited to an injured spinal cord. In at least one embodiment of the method, the method comprises the step of administering to the mammal in need thereof with a pharmaceutical composition, or pharmaceutically acceptable salt, comprising 4-aminopyridine-3-methanol. | 06-02-2011 |
Stephen R. Cakebread, Pleasant Ridge, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20120298083 | TWO-STROKE HEAVY FUEL ENGINE - A two-stroke internal combustion engine is provided. The two-stroke engine can be integrated into a variety of devices, including for example unmanned aerial vehicles, and can operate on heavy fuels including JP-5 and JP-8, for example. In some embodiments, engine can include a crankshaft including first and second main shaft portions interconnected by an offset crank web. The offset crank web can include opposing end portions that are offset from each other and define spaced apart centerlines generally perpendicular to and coplanar with the crankshaft centerline. In other embodiments, the engine can provide improvements in engine cooling, engine exhaust, lubrication delivery, engine mounting, engine fuel delivery and propeller attachment, for example. | 11-29-2012 |
Stephen R. Carsello, Plantation, FL US
| Patent application number | Description | Published |
|---|---|---|
| 20090214035 | METHOD AND APPARATUS FOR SECURE COMMUNICATION IN A DIGITAL TWO WAY RADIO PROTOCOL - A method and apparatus for secure communication in a digital two way radio protocol is disclosed herein. The method includes the step of, at an originating radio, generating at least one control value ( | 08-27-2009 |
Stephen R. Christensen, Windham, NH US
| Patent application number | Description | Published |
|---|---|---|
| 20120073625 | Air supported photovoltaic system - An air supported photovoltaic system includes a primary inflatable member with at least one facet thereon and a curved surface configured to rock the inflatable member and change the orientation of the facet to angle it towards the sun. A flexible array of photovoltaic cells is applied to the facet. | 03-29-2012 |
Stephen R. Cragg, Shrosphire GB
| Patent application number | Description | Published |
|---|---|---|
| 20100024565 | METHOD OF CONSIDERING THE DYNAMIC BEHAVIOR OF A MOVABLE MEMBER OF A MACHINE FOR PERFORMING A WHEEL FATIGUE TEST - A method of considering the dynamic behaviour of a movable member of a machine for performing a wheel fatigue test, the wheel including a disc and a rim, the method including mounting the wheel by fixing the wheel rim relative to a fixed structure of the machine, and securing the disc relative to the movable member which is movable to transmit a cyclical bending moment to the wheel, exerting a cyclical force on the movable member to generate the bending moment, at a distant position from the wheel, and while exerting the cyclical force, determining an indication of bending moment in the movable member at a first position between the wheel and the distant position, determining an indication of bending moment in the movable member at a second position between the first position and the distant position, and using the indications of bending moment at both of the first and second positions to determine an actual bending moment applied to the wheel. | 02-04-2010 |
Stephen R. Cragg, Telford GB
| Patent application number | Description | Published |
|---|---|---|
| 20110298271 | WHEEL CONSTRUCTION - A wheel construction ( | 12-08-2011 |
Stephen R. Davio, Fairport, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20080293728 | Complexes Comprising alpha2-Adrenergic Receptor Agonists and Compositions - A complex comprises at least an α | 11-27-2008 |
| 20100104551 | METHOD FOR PROLONGING ACTIVITY OF AUTODEGRADABLE ENZYMES AND COMPOSITIONS THEREOF - A composition of a long-acting enzyme comprises the enzyme in a formulation comprising a buffer and an additive selected from the group consisting of tranexamic acid, ε-aminocaproic acid, and analogs of L-lysine other than tranexamic acid and ε-aminocaproic acid, combinations thereof, and mixtures thereof. The composition can further comprise another additive selected from the group consisting of L-lysine, L-arginine, L-ornithine (or its pharmaceutically acceptable salts; e.g., L-ornithine hydrochloride), γ-aminobutyric acid, 5-aminovaleric acid, 7-aminoheptanoic acid, glycylglycine, triglycine, N-α-acetyl-L-arginine, betaine, sarcosine, gelatin, HSA, streptokinase, tPA, uPA, non-ionic surfactants, glycerin, D-sorbitol, combinations thereof, and mixtures thereof. A method for prolonging the activity of an autodegradable enzyme comprises storing the enzyme after manufacture at a low pH, and reconstituting the acidified enzyme before use with a solution containing at least one of such additives. The method is useful to provide enzyme for wide use, which otherwise would lose activity upon long storage. In one embodiment the method is applicable to provide enzyme for inducing controlled posterior vitreous detachment. | 04-29-2010 |
| 20100125077 | Polymorphs of Brimonidine Pamoate - A brimonidine pamoate polymorph exhibits characteristics disclosed herein. The polymorph is included in a composition, device, or implant for use in the treatment or control of elevated intraocular pressure or in the neuroprotection of components of a neurological tissue to prevent progressive degeneration of such components. In particular, such a composition, device, or implant can be used to provide neuroprotection to cells and components of the optic nerve system. | 05-20-2010 |
| 20100305514 | INTRAVITREAL INJECTION SYSTEM HAVING COAXIAL CANNULAE AND USE THEREOF - An ophthalmic injection system having coaxial cannulae includes a plurality of syringe bodies and a plurality of cannulae, wherein a first non-flexible cannula is configured to accommodate and guide a second cannula that moves inside the first cannula and penetrates into the internal cavity of an eye globe. The first cannula is long enough to penetrate one or more outer layers of the eye globe. A syringe body is connected to the second cannula for accommodation and infusion of a pharmaceutical composition. A plunger is inserted into an annular space of the second syringe body at its distal end for injecting the pharmaceutical composition to the surgical site. | 12-02-2010 |
| 20110183946 | Complexes Comprising alpha2-Adrenergic Receptor Agonists and Methods of Providing Neuroprotection or Treating or Inhibiting Progression of Glaucoma - A complex comprises at least an α | 07-28-2011 |
| 20120015951 | Polymorphs of Brimonidine Pamoate - A brimonidine pamoate polymorph exhibits characteristics disclosed herein. The polymorph is included in a composition, device, or implant for use in the treatment or control of elevated intraocular pressure or in the neuroprotection of components of a neurological tissue to prevent progressive degeneration of such components. In particular, such a composition, device, or implant can be used to provide neuroprotection to cells and components of the optic nerve system. | 01-19-2012 |
Stephen R. Della Vedova, Brightwaters, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110239774 | FATIGUE TESTING A SAMPLE BY CYCLICAL APPLICATION OF UNIDIRECTIONAL STRESS - A sample having a known mass and stiffness is rigidly secured to an axially elongated beam having a mass and a stiffness that are very large as compared to the mass and stiffness of the sample. The beam is then caused to resonate in the free-free mode. This subjects the sample to cyclical unidirectional stress. Advantageously, resonance of the beam occurs at an audio frequency, permitting severe fatigue tests requiring tens of millions of cycles to be completed in a relatively short time. | 10-06-2011 |
Stephen R. Erbert, Rowlett, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20110169867 | MOVING OBJECT DETECTION, TRACKING, AND DISPLAYING SYSTEMS - Moving object detecting, tracking, and displaying systems are provided. Systems illustratively include a graphical user interface and a processing unit. The processing unit is a functional part of the system that executes computer readable instructions to generate the graphical user interface. The graphical user interface may include an alert and tracking window that has a first dimension that corresponds to a temporal domain and a second dimension that corresponds to a spatial domain. In some embodiments, alert and tracking windows include target tracking markers. Target tracking markers optionally provide information about moving objects such as, but not limited to, information about past locations of moving objects and information about sizes of moving objects. Certain embodiments may also include other features such as zoom windows, playback controls, and graphical imagery added to a display to highlight moving objects. | 07-14-2011 |
Stephen R. Extance, New Milford, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20090192673 | BICYCLE USER INTERFACE SYSTEM AND METHOD OF OPERATION THEREOF - A bicycle is disclosed having a control system with a user interface and an active suspension system. The control system includes a one or more sensors arranged to measure and transmit a signal indicative of the terrain over which the bicycle is being ridden. The active suspension system includes a valve box that is fluidly coupled to each chamber of the lower cylinder. An orifice in the valve box is changed in size in response to a signal from a sensor associated with the front wheel that changes the response of the suspension system due to changing terrain conditions. The user interface includes a selection device mounted to the handlebars that allows the user to change parameters of the active suspension system during operation of the bicycle. | 07-30-2009 |
| 20120130591 | BICYCLE USER INTERFACE SYSTEM AND METHOD OF OPERATION THEREOF - A bicycle is disclosed having a control system with a user interface and an active suspension system. The control system includes a one or more sensors arranged to measure and transmit a signal indicative of the terrain over which the bicycle is being ridden. The active suspension system includes a valve box that is fluidly coupled to each chamber of the lower cylinder. An orifice in the valve box is changed in size in response to a signal from a sensor associated with the front wheel that changes the response of the suspension system due to changing terrain conditions. The user interface includes a selection device mounted to the handlebars that allows the user to change parameters of the active suspension system during operation of the bicycle. | 05-24-2012 |
Stephen R. Fahnestock, Wilmimgton, DE US
| Patent application number | Description | Published |
|---|---|---|
| 20100158822 | PEPTIDES THAT BIND TO SILICA-COATED PARTICLES - Peptides having strong affinity for silica as well as surfaces comprising silica are described. The silica-binding peptides may be used to construct peptide based-reagents suitable for delivery of a silica-coated particulate benefit agent to a surface, such as body surface, for personal care and cosmetic applications. Peptide-based reagents formed by coupling at least one of the silica-binding peptides to at least one body surface-binding peptide, either directly or through a spacer, are described. The peptide-based reagents may be used in conjunction with at least one silica-coated colorant to color body surfaces. | 06-24-2010 |
Stephen R. Garchow, Libertyville IL
| Patent application number | Description | Published |
|---|---|---|
| 20080243058 | FLUID DELIVERY SYSTEM AND FLOW CONTROL THEREFOR - A fluid delivery system having a closed-loop control process for delivering a medical fluid to a patient. A fluid infusion system includes a pump for delivering a fluid to a patient via an administration tube. A flow sensor associated with the administration tube provides an indication of the actual flow rate of fluid in the administration tube. Such a flow sensor may comprise a positive displacement flow sensor constructed using micro-fabrication and/or micro-molding techniques. A reader reads the actual flow rate signal and provides an indication to a controller for controlling the pump. The flow rate information can also be used for providing status information, such as the existence of a blockage in the fluid delivery system. | 10-02-2008 |
Stephen R. Garchow, Libertyville, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20080243057 | FLUID DELIVERY SYSTEM AND FLOW CONTROL THEREFOR - A fluid delivery system having a closed-loop control process for delivering a medical fluid to a patient. A fluid infusion system includes a pump for delivering a fluid to a patient via an administration tube. A flow sensor associated with the administration tube provides an indication of the actual flow rate of fluid in the administration tube. Such a flow sensor may comprise a positive displacement flow sensor constructed using micro-fabrication and/or micro-molding techniques. A reader reads the actual flow rate signal and provides an indication to a controller for controlling the pump. The flow rate information can also be used for providing status information, such as the existence of a blockage in the fluid delivery system. | 10-02-2008 |
| 20080255502 | FLUID DELIVERY SYSTEM AND FLOW CONTROL THEREFOR - A fluid delivery system having a closed-loop control process for delivering a medical fluid to a patient. A fluid infusion system includes a pump for delivering a fluid to a patient via an administration tube. A flow sensor associated with the administration tube provides an indication of the actual flow rate of fluid in the administration tube. Such a flow sensor may comprise a positive displacement flow sensor constructed using micro-fabrication and/or micro-molding techniques. A reader reads the actual flow rate signal and provides an indication to a controller for controlling the pump. The flow rate information can also be used for providing status information, such as the existence of a blockage in the fluid delivery system. | 10-16-2008 |
Stephen R. Geurin, Milford, NH US
| Patent application number | Description | Published |
|---|---|---|
| 20100059532 | Plastic Container Having Reinforced Gripping Structure - A plastic container includes a generally cylindrical main body portion having a longitudinal axis. At least one gripping recess is defined in the main body portion that has an oblong shape when viewed in front elevation and that is defined in part by a curved concave inner surface when viewed in side elevation. The gripping recess includes a plurality of horizontal indentations, each of which is sized to receive a finger of a consumer when the plastic container is being gripped by the consumer. | 03-11-2010 |
Stephen R. Gilfus, Woodbridge, VA US
| Patent application number | Description | Published |
|---|---|---|
| 20090317786 | INTERNET-BASED EDUCATION SUPPORT SYSTEM AND METHODS - A system and methods for implementing education online by providing institutions with the means for allowing the creation of courses to be taken by students online, the courses including assignments, announcements, course materials, chat and whiteboard facilities, and the like, all of which are available to the students over a network such as the Internet. Various levels of functionality are provided through a three-tiered licensing program that suits the needs of the institution offering the program. In addition, an open platform system is provided such that anyone with access to the Internet can create, manage, and offer a course to anyone else with access to the Internet without the need for an affiliation with an institution, thus enabling the virtual classroom to extend worldwide. | 12-24-2009 |
Stephen R. Giumentaro, Windsor, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20110191259 | Financial Document Request and Retrieval - Requests for physical documents matching one or more transaction document images may be processed by a request clearinghouse system. For example, the request clearinghouse system may identify the requested physical document and determine a storage location thereof. Upon identifying the storage location, the request clearinghouse system may add the request to a worklist of the storage location. Each storage location may have its own worklist. Upon completion of a task (e.g., processing of a request), the storage location may transmit a confirmation to the request clearinghouse system. The request clearinghouse system may notify the requesting party that the request was processed. Additionally or alternatively, storage location systems may transmit transaction information to the request clearinghouse system upon detection of a new physical document or transaction. This information may include document images, transaction parties, transaction amounts and the like. | 08-04-2011 |
Stephen R. Grobmyer, Gainesville, FL US
| Patent application number | Description | Published |
|---|---|---|
| 20100254911 | MULTIMODAL NANOPARTICLES FOR NON-INVASIVE BIO-IMAGING - Multimodal nanoparticles are nanoparticles containing contrast agents for PAT and one or more of luminescence imaging, x-ray imaging, and/or MRI. The multimodal nanoparticles can have a dielectric core comprising an oxide with a metal coating on the core. The particles can be metal speckled. The multimodal nanoparticles can be used for therapeutic purposes such as ablation of tumors or by neutron capture in addition to use as contrast agents for imaging. | 10-07-2010 |
| 20110020228 | TARGETED CELLULAR SELECTIVITY OF SURFACE ACTIVE MOLECULES - A method for the treatment of cancer involves delivering a surface active agent to an organism, where the surface active agent selectively partitions to and kills cancer cells as opposed to healthy cells. The surface active agent can be an ionic or a non-ionic surfactant with a HLB of less than 29 or a mixture of surface active agents with a HLB of less than 40, where the hydrophobic portion is a lesser fraction of the surface active agent than the hydrophilic portion. A fluorescence method of detecting and locating cancer cells in an organism involves delivering a surface active agent, where the surface active agent includes a fluorescence moiety that upon selective partitioning of the surface active agent to the cancer cells and irradiation by a radiation source to excite the fluorescence moiety, a fluorescence emission is observed permitting the detection and location of the cancerous tissue by local volumes of relatively high intensity emission. | 01-27-2011 |
Stephen R. Horan, Jr., Hickory, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20090310924 | Attachment Structure Allowing Movement and Protection of a Tether of a Cable Assembly - A cable assembly comprising a fiber optic cable and one or more attachment points to allow one or more tethers to optically connect to optical fibers within the cable. The cable assembly may be used as a drop cable for extending optical connections to a plurality of points. An attachment structure is provided for maintaining the tether to the cable to prevent damage to the tether. The attachment structure provides a loose attachment to allow the tether to move relative to the distribution cable, so the tether can move in a generally translational movement, is able to slightly twist, and to have limited lateral movement during coiling, installation, and removal of the cable assembly. This loose attachment structure may prevent damage to the tether due to forces being placed on the cable, such as during coiling or uncoiling of the cable. In one exemplary embodiment, the attachment structure is attached to the cable and receives the tether. In another exemplary embodiment, the attachment structure include a protective covering. In another embodiment, both are employed in combination. | 12-17-2009 |
Stephen R. Jaspers, Brewster, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110318350 | ANTIBODIES THAT BIND BOTH IL-17A AND IL-17F AND METHODS OF USING THE SAME - The present invention relates to blocking, inhibiting, reducing, antagonizing or neutralizing the activity of IL-17A and IL-17F. IL-17A and IL-17F are cytokines that are involved in inflammatory processes and human disease. The present invention includes antibodies that bind both IL-17A and IL-17F, as well as methods of using the same in inflammation. | 12-29-2011 |
| 20120177653 | ANTIBODIES THAT BIND BOTH IL-17A AND IL-17F AND METHODS OF USING THE SAME - The present invention relates to blocking, inhibiting, reducing, antagonizing or neutralizing the activity of IL-17A and IL-17F. IL-17A and IL-17F are cytokines that are involved in inflammatory processes and human disease. The present invention includes antibodies that bind both IL-17A and IL-17F, as well as methods of using the same in inflammation. | 07-12-2012 |
| 20120177655 | ANTI-HUMAN IL-21 MONOCLONAL ANTIBODIES - Human anti-human IL-21 monoclonal antibodies and the hybridomas that produce them are presented. Certain of these antibodies have the ability to bind native human IL-21, a mutant recombinat IL-21 protein and/or peptide regions of human IL-21. These human anti-IL-21 antibodies are useful in therapeutic treatment of autoimmune and inflammatory diseases, particularly diseases mediated by T follicular helper cells, B cells T | 07-12-2012 |
| 20120225065 | ANTI-HUMAN IL-21 MONOCLONAL ANTIBODIES - Human anti-human IL-21 monoclonal antibodies and the hybridomas that produce them are presented. Certain of these antibodies have the ability to bind native human IL-21, a mutant recombinant IL-21 protein and/or peptide regions of human IL-21. These human anti-IL-21 antibodies are useful in therapeutic treatment of autoimmune and inflammatory diseases, particularly diseases mediated by T follicular helper cells, B cells T | 09-06-2012 |
| 20120282250 | IL-21 ANTAGONISTS - Monoclonal antibodies are identified that bind the IL-21 protein. These antibodies are used to identify regions of the IL-21 protein to where binding neutralizes IL-21 activity. Hybridomas and methods of producing anti-IL-21 monoclonal antibodies are described. The monoclonal antibodies are useful in treating IL-21-mediated diseases, which may include autoimmune and inflammatory diseases such as pancreatitis, type I diabetes (IDDM), Graves Disease, inflammatory bowel disease (IBD), Crohn's Disease, ulcerative colitis, irritable bowel syndrome, multiple sclerosis, rheumatoid arthritis, diverticulosis, systemic lupus erythematosus, psoriasis, ankylosing spondylitis, scleroderma, systemic sclerosis, psoriatic arthritis, osteoarthritis, atopic dermatitis, vitiligo, graft vs. host disease (GVHD), cutaneous T cell lymphoma (CTCL), Sjogren's syndrome, glomerulonephritis, IgA nephropathy, graft versous host disease, transplant rejection, atopic dermatitis, anti-phospholipid syndrome, and asthma, and other autoimmune diseases. | 11-08-2012 |
| 20120294862 | ANTAGONISTS OF IL-17A, IL-17F, AND IL-23P19 - The present invention relates to blocking, inhibiting, reducing, antagonizing or neutralizing the activity of IL-17A, IL-17F, and IL-23. Antagonists include antibodies and antibody fragments that bind IL-23 and that bind IL-17A or IL-17F, such as antibodies that are cross-reactive for IL-17A and Il-17F. Antagonists that include an antibody or antibody fragment that binds IL-23 and an antibody or antibody fragment that binds IL-17A or IL-17F on one molecule are also disclosed. Antibodies and antibody fragments that bind IL-23 and IL-17F but that do not bind IL-17A are also disclosed. IL-17 and IL-23 are cytokines that are involved in inflammatory processes and human disease. | 11-22-2012 |
Stephen R. Johnson, Eagan, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20120243938 | Pavement Crack Router - A pavement crack router includes a plurality of bits rotatably mounted to a frame in a direction. A ratchet gear is rotatable with a wheel mounted to the frame. A movable safety release is operably connected to a ratchet rod pivotable between an engaging position engaged with the ratchet gear preventing rotation of the wheel in a reverse direction and a releasing position disengaged from the ratchet gear allowing free rotation of the wheel. An elastomeric inner tube is mounted around a lower end of each of two handle bars and is slideably received in an outer tube fixed to the frame. Two elastomeric washers are mounted around the lower end of each handle bar and sandwich the inner tube within the outer tube. A switch is operable to lower the frame and bits for opening and cleaning a crack in pavement. | 09-27-2012 |
Stephen R. King, Santa Cruz, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100237245 | SHUTTERLESS INFRARED IMAGER ALGORITHM WITH DRIFT CORRECTION - An infrared imaging system having functionality for maintaining image quality in the presence of temperature drift of the system. Such functionality is applied repetitively to maintain image quality of a target scene, yet without continuous actuation of a shutter of the system. The functionality of the imaging system results from implementing an imager algorithm. In use, the imager algorithm functions with a calibration curve created for the imaging system, with the curve comprising a plot of system output versus target scene temperature. | 09-23-2010 |
Stephen R. Koshorek, Royal Oak, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20100052360 | Door Assembly and Method for a Vehicle - A door assembly for a vehicle includes an outer panel. A support panel is operatively connected to the outer panel and configured such that the support panel provides bending resistance to the outer panel when the outer panel is deflected toward the support panel during a first deflection distance of the outer panel. A cable is operatively connected in the door assembly between a first end and a second end of the outer panel such that the cable provides additional bending resistance to the outer panel when the outer panel is deflected toward the support panel during a second deflection distance of the outer panel, greater than the first deflection distance. | 03-04-2010 |
Stephen R. Kosic, San Diego, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100001787 | DYNAMICALLY-DRIVEN DEEP N-WELL CIRCUIT - A circuit includes an NMOS transistor having a drain and a source, a p-well containing the drain and the source, an n-well under the p-well, and a first well switch configured to selectively connect the n-well to a predetermined voltage in response to an enable phase of a first switching signal. The first well switch can be configured to connect the n-well to the predetermined voltage during the enable phase of the first switching signal and to electrically float the n-well during a non-enable phase of the first switching signal. | 01-07-2010 |
| 20110025407 | DYNAMICALLY DRIVEN DEEP N-WELL CIRCUIT - A circuit can include an NMOS transistor having a drain and a source, a p-well containing the drain and the source, an n-well under the p-well, a circuit node, and a connection element connecting the n-well to the circuit node. The connection element can include a diode having an anode terminal connected to the circuit node and a cathode terminal connected to the n-well, a resistor having a first terminal connected to the circuit node and a second terminal connected to the n-well, a conductor directly connecting the n-well to the circuit node, or a well switch configured to connect the n-well to the circuit node during an enable phase of a switching signal and to electrically float the n-well during a non-enable phase of the switching signal. The diode can include a diode-connected transistor. The circuit node can be configured to receive a predetermined voltage having a magnitude equal to or greater than an upper supply voltage. | 02-03-2011 |
Stephen R. Lafaille, Harrisville, RI US
Stephen R. Miele, Jr., Wellesley, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120022994 | Large Block Trading System with Trading Controls for Aggressive Pricing - A system and method for trading large blocks of securities with controls for limiting trading under conditions of aggressive pricing are described The system and method are preferably used by a buyer or seller in the electronic trading of securities in dark pools, e.g., and ATS or ECN, that include algorithmic trading or other computer-based programmed trading. Preferably, the system and method will be automatically activated to control trading volume when the price of a security being traded becomes aggressive and priced outside of the trader's target price instructions. | 01-26-2012 |
Stephen R. Missler, Grand Rapids, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20080226744 | DIETARY SUPPLEMENT AND RELATED METHOD - A composition including a unique combination of fruits, vegetables, herbs, and optionally vitamins, minerals and specialty ingredients. The composition can include a fruit ingredient, a vegetable ingredient and an herbal ingredient, wherein the fruit ingredient is at least one of pomegranate and citrus bioflavonoids, wherein the vegetable ingredient, is at least one of asparagus, lutein, lycopene and watercress, and wherein the herbal ingredient is at least one of basil, oregano and rosemary. The composition can be administered to subjects to correct a dietary deficiency of phytochemicals and other nutrients, improve plasma concentrations of antioxidant nutrients, and increase the activity of genetic mechanisms for DNA repair and stability. | 09-18-2008 |
Stephen R. Novascone, Idaho Falls, ID US
| Patent application number | Description | Published |
|---|---|---|
| 20090022010 | EARTH ANALYSIS METHODS, SUBSURFACE FEATURE DETECTION METHODS, EARTH ANALYSIS DEVICES, AND ARTICLES OF MANUFACTURE - Earth analysis methods, subsurface feature detection methods, earth analysis devices, and articles of manufacture are described. According to one embodiment, an earth analysis method includes engaging a device with the earth, analyzing the earth in a single substantially lineal direction using the device during the engaging, and providing information regarding a subsurface feature of the earth using the analysis. | 01-22-2009 |
| 20110290101 | SEQUENTIAL INJECTION GAS GUNS FOR ACCELERATING PROJECTILES - Gas guns and methods for accelerating projectiles through such gas guns are described. More particularly, gas guns having a first injection port located proximate a breech end of a barrel and a second injection port located longitudinally between the first injection port and a muzzle end of the barrel are described. Additionally, modular gas guns that include a plurality of modules are described, wherein each module may include a barrel segment having one or more longitudinally spaced injection ports. Also, methods of accelerating a projectile through a gas gun, such as injecting a first pressurized gas into a barrel through a first injection port to accelerate the projectile and propel the projectile down the barrel past a second injection port and injecting a second pressurized gas into the barrel through the second injection port after passage of the projectile and to further accelerate the projectile are described. | 12-01-2011 |
| 20110305111 | EARTH ANALYSIS METHODS, SUBSURFACE FEATURE DETECTION METHODS, EARTH ANALYSIS DEVICES, AND ARTICLES OF MANUFACTURE - Earth analysis methods, subsurface feature detection methods, earth analysis devices, and articles of manufacture are described. According to one embodiment, an earth analysis method includes engaging a device with the earth, analyzing the earth in a single substantially lineal direction using the device during the engaging, and providing information regarding a subsurface feature of the earth using the analysis. | 12-15-2011 |
Stephen R. Okros, Ocean, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20090053663 | Germ protective cake cover - The present invention is a transparent dessert cover designed to shield confections, such as cakes, from germs resulting particularly from those attempting to blow out candles, while maintaining the aesthetic appearance of the cake. In the preferred mode, the cover is constructed of freezer-proof plastic material, and molded in the shape of a particular confection, such as a round or rectangular birthday cake. The upper portion of the cover contains recessed holes to accommodate a predetermined number of candles, as well as at least one slot in which a celebratory message such as “Happy Birthday” may be inserted. Importantly, individual letters are provided for the user to spell out particular names or messages, as desired. Finally, a sturdy, attachable bottom piece is provided with the cover to facilitate transportation and storage of the cake. | 02-26-2009 |
Stephen R. Petteway, Jr., Cary, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20100047228 | RECOMBINANTLY MODIFIED PLASMIN - Methods of using polynucleotides and polypeptides relating to a recombinantly-modified plasmin(ogen) molecule are provided, including methods related to vitrectomy or vitreolysis. The plasmin(ogen) molecule has a single kringel domain N-terminal to the activation site present in the native human plasminogen molecule, and exhibits lysine-binding and significant enzymatic characteristics associated with the native enzyme. | 02-25-2010 |
Stephen R. Pitzl, Shoreview, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20100305643 | VENTILATION SENSOR RATE RESPONSE NORMALIZATION AND CALCULATION - A cardiac rhythm management (CRM) device can extract ventilation information from thoracic impedance or other information, and adjust a delivery rate of the CRM therapy. A tidal volume of a patient is measured and used to adjust a ventilation rate response factor. The measured tidal volume can optionally be adjusted using a ventilation rate dependent adjustment factor. The ventilation rate response factor can also be adjusted using a maximum voluntary ventilation (MVV), an age predicted maximum heart rate, a resting heart rate, and a resting ventilation determined for the patient. In various examples, a global ventilation sensor rate response factor (for a population) can be programmed into the CRM device, and automatically tailored to be appropriate for a particular patient. | 12-02-2010 |
Stephen R. Plymate, Des Moines, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20090110678 | RECEPTOR ANTAGONISTS FOR TREATMENT OF METASTATIC BONE CANCER - The invention provides methods of treating bone cancer, particularly metastatic bone cancer, by administering an IGF-IR antagonist and/or a PDGFRα antagonist. The invention also provides antibodies that bind to human PDGFRα and neutralize activation of the receptor. The invention further provides a methods for neutralizing activation of PDGFRα, and a methods of treating a mammal with a neoplastic disease using the antibodie alone or in combination with other agents. | 04-30-2009 |
| 20090175868 | IGF-IR antagonists as adjuvants for treatment of prostate cancer - The present invention relates to a method of treating prostate cancer with androgen deprivation therapy and an insulin-like growth factor receptor (IGF-IR) antagonist. Although the response rate of prostate cancer to androgen deprivation therapy (ADT) is high, surviving cancer cells invariably become androgen independent (AI) and tumor growth follows. The invention inhibits or delays transition of androgen dependent cancer to androgen independent cancer, significantly decreases risk of recurrence, and improves treatment outcome. | 07-09-2009 |
Stephen R. Rakower, Corona Del Mar, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20120245510 | ADHESIOLYSIS SYSTEM - Methods and apparatus for creating and maintaining a progressive pneumoperitoneum over a prolonged duration of time are provided. In some aspects, an apparatus may include a first elongate member having a proximal end, a distal end, and a first lumen extending from the distal end to the proximal end. The apparatus may further include a fixation member disposed between the distal end and the proximal end and configured to secure the apparatus relative to the abdominal wall of a patient. The apparatus may further include a pressure sensor in fluid communication with the first lumen configured to facilitate obtaining an intraperitoneal pressure measurement. | 09-27-2012 |
Stephen R. Sammataro, Madison, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20120067671 | SEALED BEARING ASSEMBLY FAILURE DETECTION - A method and system for magnetically detecting thermal degradation of a component. A multiple of ferrous metal segments are attached to a component not within a lubrication circuit of a lubrication system with a thermally-affected bonding agent. The thermally-affected bonding agent is operable to detach at a threshold temperature at least one of the multiple of ferrous metal segments such that the at least one of the multiple of detached ferrous metal segments enters the lubrication circuit of the lubrication system. The at least one of the multiple of ferrous metal segments which detached are then detected within the lubrication system. | 03-22-2012 |
Stephen R. Samms, Mesa, AZ US
| Patent application number | Description | Published |
|---|---|---|
| 20090036303 | METHOD OF FORMING A CO-FIRED CERAMIC APPARATUS INCLUDING A MICRO-READER - A method is provided for placing high surface area catalyst material ( | 02-05-2009 |
Stephen R. Schmidt, Silver Spring, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20120071614 | CATALYST ON SILICA CLAD ALUMINA SUPPORT - The invention concerns catalysts comprising (i) a cladded catalyst support comprising (a) a core which comprises alumina particles and (b) about 1 to about 40 weight percent silica cladding, based on the weight of the cladded catalyst support, on the surface of the core; the catalyst support having a BET surface area of greater than 20 m2/g and a porosity of at least about 0.2 cc/g; and (ii) 0.1 to 10 weight percent, based on the weight of the catalyst, of catalytically active transition metal on the surface of the cladded catalyst support; wherein the catalyst support has a normalized sulfur uptake (NSU) of up to 25 ?g/m2. The invention also concerns the production and use of such catalysts. | 03-22-2012 |
Stephen R. Schwallie, Lake Villa, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20120014622 | Disposable storage bags - Disposable storage bags are disclosed having a first side wall, a second side wall and a bottom portion which forms the bag and having an open top portion for receiving and removing items to be stored such as snack foods or other material. Near the top opening of the bag is a closure mechanism for opening and closing the bag. The side walls of the bag are tapered inwardly from the top portion toward the bottom portion such that quillons are formed when the bag is filled with items such as snack food or other material. The bottom portion of the bag includes a gusset which, when the bag is filled with snack food or other material, expands and opens such that the bag may stand upright. | 01-19-2012 |
Stephen R. Shierry, Villa Park, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20100033291 | HOUSING SECURING APPARATUS FOR ELECTRICAL COMPONENTS, ESPECIALLY FUSES - An electric component includes: an insulating housing; a conductive member inserted into the housing until hitting a stop provided by the housing, the conductive member configured to mate with a conductive portion of a device that mates with the electrical component, the mating device thereby applying a force to the conductive portion, the conductive member including a wall, the wall defining a projection that is at least substantially coplanar with the wall; and wherein the housing includes a catch that flexes when the conductive member is inserted into the housing to allow the projection to move past the catch so that the conductive member can hit the stop, at which point the catch unflexes into locking engagement with the projection. | 02-11-2010 |
Stephen R. Shorofsky, Owings Mills, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20100262203 | DETERMINATION OF SITE OF ORIGIN FOR A NATURAL ELECTRICAL PULSE IN A LIVING BODY - Techniques include determining a first vector of temporal changes in electrical data measured at multiple electrical sensors positioned at corresponding locations on a surface of a living body due to a natural electrical pulse. A different vector of temporal changes in electrical data measured at the same electrical sensors is determined due to each stimulated signal of multiple stimulated signals within the living body. Stimulated position data is received, which indicates a different corresponding position within the living body where each of the stimulated signals originates. The site of origin of the natural electrical pulse is determined based on the first vector and the multiple different vectors and the stimulated position data. Among other applications, these techniques allow the rapid, automatic determination of the site of origin of ventricular tachycardia arrhythmia (VT). | 10-14-2010 |
Stephen R. Smiaroski, South Deerfield, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090178946 | CONTAINER ASSEMBLY - A container assembly for the storage and transport of goods, the assembly including a first portion having an interior with a substantially flat interior bottom surface. The assembly further includes a second portion pivotally connected to the first portion. The first portion has an outer surface that includes a first stacking pattern and the second portion has an outer surface that includes a second stacking pattern which is different from the first stacking pattern and configured to engage the first stacking pattern enabling the container assembly to be bi-directionally stacked on another of the container assemblies. | 07-16-2009 |
Stephen R. Smith, Tucker, GA US
| Patent application number | Description | Published |
|---|---|---|
| 20100072025 | CONVEYOR SWITCH FOR BAKED GOODS - A system and method of conveying objects. A switching station is operated in coordination with gaps formed in a first product stream carried on an upstream conveyor, to split the first product stream into two or more second product streams carried on downstream conveyors. | 03-25-2010 |
| 20120042785 | CONVEYORIZED BAKING OVEN WITH STEAM TUNNEL - A system and method for applying steam to baked products in a conveyorized oven. A steam tunnel sub-enclosure includes exhaust ducts collecting steam at the conveyor's entrance and exit thereof to prevent steam from being released into the rest of the oven where it might interfere with ignition control equipment. | 02-23-2012 |
Stephen R. Smith, Holly, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20100102664 | METHODS AND APPARATUS FOR SURFACE PREPARATION IN ULTRASONIC JOINTS - A method of joining the ends of wire windings for a motor stator or the like includes preparing a surface at each end (e.g., by removing any enamel coating), deforming the surfaces to produce knurls, striations, and the like, and then ultrasonically bonding the two surfaces to produce the bond between windings, thereby providing a joint with improved strength. | 04-29-2010 |
| 20120216398 | Systems and Methods for Joining Wires of a Motor Stator - An apparatus for joining a wire pair of a stator coil. The apparatus includes a tool having a pair of electrodes and control equipment. The control equipment is configured to control the electrodes to apply force to the wire pair to push adjacent wires of the wire pair toward each other and cause current to pass between the pair of electrodes, and so through the wire pair pushed together, at a time at which the force is being applied to the wire pair. | 08-30-2012 |
| 20120293034 | STATOR FOR AN ELECTRIC MOTOR - A stator for an electric motor includes first and second rows of conductors arranged concentrically around an axis inside a steel core. Each conductor includes a linking end. The stator also includes a first dielectric shim ring arranged between the two rows of conductors. Each conductor of the first row is bent in either a clockwise or a counter-clockwise direction relative to the axis and each conductor of the second row is bent in the opposite direction. The linking end of each conductor of the first row is attached to the linking end of an adjacent conductor of the second row after the conductors are bent. The first shim ring separates the first and second rows of conductors when the conductors are being bent, and is also at least partially disposed between the first and second rows of conductors when the linking ends are being attached. | 11-22-2012 |
Stephen R. Synakowski, Dewitt, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100239460 | ELECTRONIC ANALYTE ASSAYING DEVICE - The invention is an electronically processed single-step test device for detecting the presence of a preselected analyte in a fluid. The device includes a hollow rectangular outer casing, disposed within co-joined upper and lower sections of the casing are assay material, an electronic processing system, and a LCD display. The LCD display is observable through a viewing window. The assay material is a sorptive material including a fluid sample application region in the form of a sample wick in fluid communication with a test strip. The test strip includes an analyte capture region adjacent to a light shield. The electronic processing system includes red and green LEDs which are alternately pulsed or energized over predetermined periods of time to determine if fluid test results show a marker or markers in the capture region indicative of the presence of a preselected analyte in the fluid. If so, Yes+ is displayed on the LCD. If not, No− is displayed on the LCD. | 09-23-2010 |
| 20100240149 | ELECTRONIC ANALYTE ASSAYING DEVICE - The invention is an electronically processed single-step test device for detecting the presence of a preselected analyte in a fluid. The device includes a hollow rectangular outer casing, disposed within co-joined upper and lower sections of the casing are assay material, an electronic processing system, and a LCD display. The LCD display is observable through a viewing window. The assay material is a sorptive material including a fluid sample application region in the form of a sample wick in fluid communication with a test strip. The test strip includes an analyte capture region adjacent to a light shield. The electronic processing system includes red and green LEDs which are alternately pulsed or energized over predetermined periods of time to determine if fluid test results show a marker or markers in the capture region indicative of the presence of a preselected analyte in the fluid. If so, Yes+ is displayed on the LCD. If not, No− is displayed on the LCD. | 09-23-2010 |
Stephen R. Targan, Santa Monica, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20120079611 | TL1A MODEL OF INFLAMMATION FIBROSIS AND AUTOIMMUNITY - This invention relates transgenic animals that overexpress TL1A in a tissue specific manner to model inflammatory bowel disease (IBM such as colitis, Crohn's disease and ulcerative colitis, fibrosis, and related inflammatory diseases and conditions. TL1A transgenic animals constitutively express both TL1A and GFP in lymphoid and myeloid cell lineages, allowing convenient identification and sorting of immune cells involved in IBD disease progression, such as T-cells, antigen presenting cells (APC), and dendritic cells (DC). TL1A transgenic animals may be induced to exhibit gross fibrosis, or isolated cells may be implanted into immunodeficient mice to establish colitis. | 03-29-2012 |
Stephen R. Thompson, Bakersfield, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090200021 | PERFORATION METHOD AND APPARATUS - A signature element is attached to a downhole cable or other protected equipment and the signal from a signature position detector is used, at least in part, to control the orientation of a directed perforating device or other directional device. Signal emitting sources can include a radioactive material added to an encapsulating composition of a downhole cable. | 08-13-2009 |
Stephen R. Tokish, Brighton, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20110077123 | METHOD AND SYSTEM FOR REDUCING DELAY IN POWER DOWNSHIFTS FOR AN AUTOMATIC TRANSMISSION - A method and control module for controlling a transmission of a vehicle includes a clutch torque load predictor module generating a predicted clutch torque load signal for the shift command and a minimum clutch pressure module generating a minimum clutch pressure signal corresponding to a minimum clutch pressure. The control module includes a pressure command module generating a commanded clutch pressure signal for the predicted clutch torque load signal based on the minimum clutch pressure signal and commanding operation of a clutch with a commanded clutch pressure signal. The control module also includes a transmission control module generating the shift command after the clutch torque load predictor module generates the predicted clutch signal, the minimum clutch pressure module generates the minimum clutch pressure signal and the pressure command module generates the commanded clutch pressure signal. | 03-31-2011 |
Stephen R. Treccase, Saugerties, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110244081 | Chocolate Containing Vitamin C and Having a Low Glycemic Load - A line of chocolate confectionery products that contains naturally occurring Vitamin C at a minimum percentage of 2% of the RDADV recommendation and 4% RDADV of fiber. The formulations contain at least 4% of the RDADV of at least 3 of the following vitamin and minerals: Potassium, Vitamin A, Vitamin C, Calcium, Iron, Vitamin K, Phosphorus, Magnesium, Zinc, and Manganese. All of these RDADVs are met without the addition of supplements. The formulations contain between 10% and 60% coconut palm sugar in order to meet the defined nutrition requirements. In order to overcome agglomeration issues the formulations contain at least 2.5% fiber. | 10-06-2011 |
Stephen R. Tudhope, County Durham GB
| Patent application number | Description | Published |
|---|---|---|
| 20090247754 | METHOD OF PREPARING HUPERZINE A AND DERIVATIVES THEREOF - The present invention is related to the synthesis of huperzine A. The synthesis includes a variety of process steps that increase productivity, reduce safety concerns, and allow for increasing production of compounds of desired optical isomer. The inventive methods may encompass a single improved reaction step that may be incorporated into a known reaction process for synthesizing huperzine A or a derivative thereof to improve the overall reaction. The inventive methods also encompass complete synthesis methods for preparing huperzine A or a derivative thereof. | 10-01-2009 |
Stephen R. Vowell, Houston, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20090098855 | METHOD AND SYSTEM FOR PROVISIONING COMMUNICATION SERVICE TO A MOBILE COMMUNICATION DEVICE TO RESTRICT USE WHEN OPERATING A VEHICLE - A mobile communication device has communication service restricted when it becomes apparent that the device is in transit. The communication system receives an access control message indicating the device is in transit. The system accesses a mobility access profile stored in a database. The mobility access profile indicates provisioning changes to be made in providing communication service to the mobile communication device while the device is in transit. | 04-16-2009 |
Stephen R. Warburton-Pitt, Queensbury, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20080267699 | METHOD OF MOLDING A CONNECTOR AND TUBING ASSEMBLY - A connector and tubing assembly including a multi-lumen molded connector having at least three flexible tubes also molded into the connector. The connector may be “Y” shaped and include three flexible tubes. A process of making the connector and tubing assembly involves forming a first part of the connector with two tubes molded therein and then removing an internal mold member prior to molding the final connector portion and third tube in place. | 10-30-2008 |
Stephen R. Wechter, Lubbock, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20110256612 | COMPOSITIONS FOR CULTURING SPIROCHETES - The present invention relates to methods and compositions for culturing spirochetes and treating spirochetal diseases. For example, the present invention provides serum-free media for culturing spirochete bacteria in vitro. The present invention further provides methods for identifying spirochete susceptibilities to antimicrobials and antimicrobial compositions and cocktails. The present invention also provides methods for treating subjects suspected of having a spirochete infection. | 10-20-2011 |
Stephen R. Wechter, Alpha, OH US
| Patent application number | Description | Published |
|---|---|---|
| 20090053796 | Methods And Compositions For Culturing Spirochetes And Treating Spirochetal Diseases - The present invention relates to methods and compositions for culturing spirochetes and treating spirochetal diseases. For example, the present invention provides serum-free media for culturing spirochete bacteria in vitro. The present invention further provides methods for identifying spirochete susceptibilities to antimicrobials and antimicrobial compositions and cocktails. The present invention also provides methods for treating subjects suspected of having a spirochete infection. | 02-26-2009 |
Stephen R. Whynot, Richardson, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20100262700 | DISTRIBUTED CALL SERVER SUPPORTING COMMUNICATION SESSIONS IN A COMMUNICATION SYSTEM AND METHOD - An apparatus, method, and computer program manage communication sessions that include a plurality of portions. Different processors handle each portion of a communication session. The apparatus, method, and computer program transfer the communication session from one of the processors to another of the processors during the different portions of the communication session. | 10-14-2010 |
Stephen R. Wolfrath, Eagan, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20120036087 | AUTOMATIC INCOME ADJUSTMENT - A method includes receiving market data associated with an investment product that specifies a first guaranteed annual withdrawal amount and a second guaranteed annual withdrawal amount, where the first guaranteed annual withdrawal amount is greater than the second guaranteed annual withdrawal amount. The method includes automatically selecting a guaranteed annual withdrawal amount from the first guaranteed annual withdrawal amount and the second guaranteed annual withdrawal amount based on at least an evaluation of the market data. | 02-09-2012 |