Patent application number | Description | Published |
20090328251 | Galactosyltransferase - The present invention provides a method of expressing a plant Lewis-type β1,3-galactosyltransferase in an organism comprising the step of providing the organism with a nucleic acid molecule comprising a sequence A which is defined as being selected from: a) a sequence according to SEQ ID NO: 1 with an open reading frame from base pair 1-1932, j) a sequence which is at least 50% identical with SEQ ID NO: 1, k) a sequence which hybridizes with SEQ ID NO: 1 under stringent conditions, or l) a sequence which has degenerated to SEQ ID NO: 1 due to the genetic code, wherein the sequences a) to d) encode a plant protein having Lewis-type β1,3-galactosyltransferase activity, or m) a sequence which is complementary to one of the sequences a) to d), and expressing a protein encoded by sequence A or if the organism comprises a sequence A in its wildtype form overexpressing a protein encoded by sequence A. | 12-31-2009 |
20100242128 | METHOD TO PRODUCE MODIFIED PLANTS WITH ALTERED N-GLYCOSYLATION PATTERN - Provided is a novel method to produce a plant cell or plant having an altered N-glycosylation pattern resulting, in particular, in a low level of β-1,2-xylose residues and core α-1,3-fucose residues on protein-bound N-glycans. The plant cell or plant is of particular interest for producing therapeutic glycoproteins with a low, or not detectable, level of β-1,2-xylose and α-1,3-fucose residues. Also provided are novel α-1,3-fucosyltransferase nucleotide sequences and uses. | 09-23-2010 |
20120331578 | Method for Producing Recombinant Glycoproteins Having Beta1,2-Bound Xylose Residues - A DNA molecule is provided which comprises a sequence according to SEQ ID NO: 8 having an open reading frame from base pair 227 to base pair 1831 or having at least 50% homology to the above-indicated sequence, or hybridizing with the above-indicated sequence under stringent conditions, or comprising a sequence which has degenerated to the above-indicated DNA sequence because of the genetic code, the sequence coding for a plant protein having β1,2-xylosyltransferase activity or being complementary thereto. | 12-27-2012 |