Stefansson
Einar Stefansson, Reykjavik IS
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20100113387 | FATTY ACIDS FOR USE AS A MEDICAMENT - The invention relates to fatty acid stimulation of rectal mucosa initiating the process of defecation, acting as a laxative. Furthermore, the invention relates to the usage of free fatty acids, fatty acid mixtures and fatty acid extracts from marine lipids in pharmaceutical formulations such as suppositories, ointments, tablets and gelatin capsules for treatment and prevention of multiple disorders like constipation, hemorrhoids, bacterial infections (e.g. | 05-06-2010 |
20120028944 | CYCLODEXTRIN NANOTECHNOLOGY FOR OPHTHALMIC DRUG DELIVERY - The invention provides an ophthalmic composition which is an aqueous suspension comprising drug, cyclodextrin and water, the composition having an aqueous phase of from about 0.1% (w/v) to about 90% (w/v) of the drug in solution, as dissolved free drug and as dissolved drug/cyclodextrin complex(es), and a solid phase of from about 10% (w/v) to about 99.9% (w/v) of the drug as solid drug/cyclodextrin particles, suspended in the aqueous phase; the size of the solid particles being from about 10 nm to about 1 mm, the drug/cyclodextrin particles being capable of dissolving in aqueous tear fluid within 24 hours of application to the eye surface. The aqueous eye suspension can be in the form of eye drops, eye gel or eye mist. Further, the invention provides a method for treating a condition of the posterior segment and/or anterior segment of the eye comprising applying to the eye surface, in an amount which delivers to said segment or segments a therapeutically effective amount of a drug suitable for treating said condition, an ophthalmic composition which is as defined above. Nasal compositions and methods and ophthalmic and nasal compositions in powder form are also provided. | 02-02-2012 |
20120179486 | INDIVIDUALIZED ALLOCATION OF HEALTH RESOURCES - The present invention discloses methods, computer program and system to overcome the limitation of the current clinical practice. This is achieved by using information technology and the vast amount of epidemiological data available to create algorithms that calculate the risk or severity profile of an individual with any given disease. The individual profile presents the current condition and/or position of the individual in comparison with the mean base curve of the total population and in accordance with upper and lower risk limits. The individual profile is then fitted with its optimal use of healthcare resources, such as medication, surgery, laser treatment, surveillance and follow-up, to optimize and individualize the health outcome of this individual, and at the same time optimize and individualize the allocation of healthcare resources within the system. | 07-12-2012 |
20130142791 | CYCLODEXTRIN NANOTECHNOLOGY FOR OPHTHALMIC DRUG DELIVERY - The invention provides an ophthalmic composition which is an aqueous suspension comprising drug, cyclodextrin and water, the composition having an aqueous phase of from about 0.1% (w/v) to about 90% (w/v) of the drug in solution, as dissolved free drug and as dissolved drug/cyclodextrin complex(es), and a solid phase of from about 10% (w/v) to about 99.9% (w/v) of the drug as solid drug/cyclodextrin particles, suspended in the aqueous phase; the size of the solid particles being from about 10 nm to about 1 mm, the drug/cyclodextrin particles being capable of dissolving in aqueous tear fluid within 24 hours of application to the eye surface. The aqueous eye suspension can be in the form of eye drops, eye gel or eye mist. Further, the invention provides a method for treating a condition of the posterior segment and/or anterior segment of the eye comprising applying to the eye surface, in an amount which delivers to said segment or segments a therapeutically effective amount of a drug suitable for treating said condition, an ophthalmic composition which is as defined above. Nasal compositions and methods and ophthalmic and nasal compositions in powder form are also provided. | 06-06-2013 |
20140186443 | CYCLODEXTRIN NANOTECHNOLOGY FOR OPHTHALMIC DRUG DELIVERY - The invention provides an ophthalmic composition which is an aqueous suspension comprising drug, cyclodextrin and water, the composition having an aqueous phase of from about 0.1% (w/v) to about 90% (w/v) of the drug in solution, as dissolved free drug and as dissolved drug/cyclodextrin complex(es), and a solid phase of from about 10% (w/v) to about 99.9% (w/v) of the drug as solid drug/cyclodextrin particles, suspended in the aqueous phase; the size of the solid particles being from about 10 nm to about 1 mm, the drug/cyclodextrin particles being capable of dissolving in aqueous tear fluid within 24 hours of application to the eye surface. The aqueous eye suspension can be in the form of eye drops, eye gel or eye mist. Further, the invention provides a method for treating a condition of the posterior segment and/or anterior segment of the eye comprising applying to the eye surface, in an amount which delivers to said segment or segments a therapeutically effective amount of a drug suitable for treating said condition, an ophthalmic composition which is as defined above. Nasal compositions and methods and ophthalmic and nasal compositions in powder form are also provided. | 07-03-2014 |
Einar Stefansson, Rejkjavik IS
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20130137771 | FATTY ACIDS FOR USE AS A MEDICAMENT - The invention relates to fatty acid stimulation of rectal mucosa initiating the process of defecation, acting as a laxative. Furthermore, the invention relates to the usage of free fatty acids, fatty acid mixtures and fatty acid extracts from marine lipids in pharmaceutical formulations such as suppositories, ointments, tablets and gelatin capsules for treatment and prevention of multiple disorders like constipation, hemorrhoids, bacterial infections (e.g. | 05-30-2013 |
Erik T. Stefansson, Cupertino, CA US
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20150270073 | SCISSOR MECHANISM FEATURES FOR A KEYBOARD - A key supported by a scissor mechanism including interlocking scissor members assembled to mutually pivot along a pivot track. A first scissor member may include a pivot track and an up-stop track and a second scissor member may include at least a first and second extension portion positioned within the pivot track and the up-stop track respectively. When the key is depressed, the first extension portion may slide and at least partially pivot or rotate within the pivot track, and the second extension portion may slide within the up-stop track. | 09-24-2015 |
Hafthor Stefansson, Phoenix, AZ US
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20150249710 | SYSTEMS AND METHODS FOR EVENT DIGITAL MEDIA FILE MANAGEMENT - Systems and methods are disclosed herein for crowd-sourced digital media file management. During public events, such as a marathon, many photographs and videos may be taken of the event and the participants in the event. A photographer may upload reduced quality digital media file previews taken of the event by the photographer, and the photographer may upload the associated high quality digital media files to a cloud storage system. The photographer and consumers viewing digital media file previews may tag the digital media file previews with metadata about the digital media file previews, such as the identities of individuals in the digital media file previews. A consumer may search for images containing specific metadata, and may purchase a high quality digital media file associated with the preview file. | 09-03-2015 |
Halldor Narfi Stefansson, Natick, MA US
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20090119677 | BI-DIRECTIONAL COMMUNICATION IN A PARALLEL PROCESSING ENVIRONMENT - A system receives an instruction from a technical computing environment, and commences parallel processing on behalf of the technical computing environment based on the received instruction. The system also sends a query, related to the parallel processing, to the technical computing environment, receives an answer associated with the query from the technical computing environment, and generates a result based on the parallel processing. The system further sends the result to the technical computing environment, where the result is used by the technical computing environment to perform an operation. | 05-07-2009 |
20100333092 | DYNAMIC DEFINITION FOR CONCURRENT COMPUTING ENVIRONMENTS - Exemplary embodiments allow a user to create configurations for use in distributed computing environments. Configurations can be arranged in hierarchies in which elements of the hierarchy can inherit characteristics from elements in other layers of the hierarchy. Embodiments also allow a user to flatten a hierarchical configuration to remove hierarchical dependencies and/or inheriting capabilities of elements in the hierarchy. Exemplary embodiments further allow users to deploy a distributed computing configuration on their desktop to evaluate performance of the configuration and then deploy the configuration in a distributed computing environment without having to change programming code run on the desktop/distributed computing environment. | 12-30-2010 |
20140365559 | DYNAMIC DEFINITION FOR CONCURRENT COMPUTING ENVIRONMENTS - Exemplary embodiments allow a user to create configurations for use in distributed computing environments. Configurations can be arranged in hierarchies in which elements of the hierarchy can inherit characteristics from elements in other layers of the hierarchy. Embodiments also allow a user to flatten a hierarchical configuration to remove hierarchical dependencies and/or inheriting capabilities of elements in the hierarchy. Exemplary embodiments further allow users to deploy a distributed computing configuration on their desktop to evaluate performance of the configuration and then deploy the configuration in a distributed computing environment without having to change programming code run on the desktop/distributed computing environment. | 12-11-2014 |
H. Narfi Stefansson, Natick, MA US
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20100198951 | DYNAMIC DEFINITION FOR CONCURRENT COMPUTING ENVIRONMENTS - A system generates an executable process for execution by a concurrent computing environment, generates a configuration that specifies configurable properties of the concurrent computing environment, and initiates execution of the executable process, with the concurrent computing environment, to initiate configuration of the concurrent computing environment based on the configurable properties of the configuration. | 08-05-2010 |
20120036235 | USE OF DYNAMIC PROFILES FOR CREATING AND USING A DISTRIBUTED COMPUTING ENVIRONMENT - A system is configured to create a profile that allows a job to be performed within a distributed computing environment comprising one or more computing devices; provide an interface that allows the profile to be specified; obtain a scheduler component via the interface, where the scheduler component identifies a scheduler to be used to perform the job and an application that at least one of the computing devices, that is specified by the scheduler, is to use when performing the job; obtain, via the interface, a project component that identifies data on which the job is to be based; and create the profile based on the scheduler component and the project component. | 02-09-2012 |
Hreinn Stefansson, Gardabaer IS
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20080263690 | NEUREGULIN-1 TRANSGENIC MOUSE AND METHODS OF USE - Nucleic acids comprising the neuregulin 1 gene (NRG1) and encoding NRG1 polypeptides are disclosed. Also described are related nucleic acids encoding NRG1 polypeptides; NRG1 polypeptides; antibodies that bind to NRG1 polypeptides; methods of diagnosis of susceptibility to schizophrenia; assays for agents that alter the activity of NRG1 polypeptide or which identify NRG1 binding agents, and the agents or binding agents identified by the assays; NRG1 therapeutic agents, including the NRG1 nucleic acids, NRG1 polypeptides, or agents that alter the activity of an NRG1 polypeptides; pharmaceutical compositions comprising the NRG1 therapeutic agents; as well as methods of therapy of schizophrenia. Novel haplotypes with a common core haplotype in affected individuals are described, as well as their use in methods for screening for susceptibility to schizophrenia. Also described are hypomorphic mice for use in identifying phenotypes associated with schizophrenia, as well as for use in assessing agents of interest for neuroleptic activity and for potential therapeutic use for treatment of schizophrenia. | 10-23-2008 |
20100047807 | GENETIC VARIANTS ASSOCIATED WITH PERIODIC LIMB MOVEMENTS AND RESTLESS LEGS SYNDROME - The present inventions discloses genetic markers and haplotypes that have been found to be associated with risk of Restless Legs Syndrome (RLS), Periodic Limb Movement Disorder (PLMD), and Periodic Limb Movements of Sleep (PLMS). Methods for determination of susceptibility of these disorders are disclosed using such markers, as are kits useful in such determination. | 02-25-2010 |
20110111419 | Copy Number Variations Predictive of Risk of Schizophrenia - The present invention relates to genomic copy number variations as risk factors for schizophrenia. The invention provides methods and kits for risk management of schizophrenia, by assessing such copy number variations in the genome of individuals. | 05-12-2011 |
Kjartan Stefansson, Lexington, MA US
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20130282346 | TRAFFIC DATA MANAGEMENT AND SIMULATION SYSTEM - Systems and methods for, inter alia, geographically based analyses of traffic being carried over a wide scale traffic network. The systems integrate geographical information systems (GIS) with traffic simulation processes to allow a user to analyze traffic patterns and loads at specific geographic locations of regions. Additionally, these systems allow for traffic analysis over a wide scale traffic network that may encompass the traffic network that exists within an geographic region and can include, as examples, the traffic networks that span across a city, that interconnect cities, that interconnect states and that run across multiple states. To this end, the systems include traffic simulators that can adaptively or controllably select between multiple traffic simulation models for simulating traffic across different segments of the traffic network. The different models provide varying levels of granularity for measurements of geographical location of a vehicle traveling over the traffic network. | 10-24-2013 |
Njall Stefansson, Mcmurray, PA US
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20120174760 | DUAL HARDNESS STEEL ARTICLE AND METHOD OF MAKING - A dual hardness steel article comprises a first air hardenable steel alloy having a first hardness metallurgically bonded to a second air hardenable steel alloy having a second hardness. A method of manufacturing a dual hard steel article comprises providing a first air hardenable steel alloy part comprising a first mating surface and having a first part hardness, and providing a second air hardenable steel alloy part comprising a second mating surface and having a second part hardness. The first air hardenable steel alloy part is metallurgically secured to the second air hardenable steel alloy part to form a metallurgically secured assembly, and the metallurgically secured assembly is hot rolled to provide a metallurgical bond between the first mating surface and the second mating surface. | 07-12-2012 |
20120321504 | AIR HARDENABLE SHOCK-RESISTANT STEEL ALLOYS, METHODS OF MAKING THE ALLOYS, AND ARTICLES INCLUDING THE ALLOYS - An air hardenable steel alloy is disclosed comprising, in percent by weight: 0.18 to 0.26 carbon; 3.50 to 4.00 nickel; 1.60 to 2.00 chromium; 0 to 0.50 molybdenum; 0.80 to 1.20 manganese; 0.25 to 0.45 silicon; 0 to less than 0.005 titanium; 0 to less than 0.020 phosphorus; 0 up to 0.005 boron; 0 up to 0.003 sulfur; iron; and impurities. The air hardenable steel alloy has a Brinell hardness in a range of 352 HBW to 460 HBW. The air hardenable steel alloy combines high strength, medium hardness and toughness, as compared with certain know air hardenable steel alloys, and finds application in, for example, any of a steel armor, a blast-protective hull, a blast-protective V-shaped hull, a blast-protective vehicle underbelly, and a blast-protective enclosure. | 12-20-2012 |
Njall Stefansson, Canonsburg, PA US
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20120067100 | Elevated Temperature Forming Methods for Metallic Materials - A method of forming a metallic article includes directly and/or indirectly inductively heating a localized region of a metallic article to a forming temperature. The metallic article may comprise materials selected from titanium alloys, nickel-base alloys, and specialty steels, e.g., stainless steel, high-strength low-alloy steel, armor steel alloys, and the like. The forming temperature may be in a forming temperature range of 0.2 to 0.5 of a melting temperature of a metallic material comprising the article. The metallic article is formed in the localized region. Devices for indirectly and directly inductively heating a localized region of a metallic article are disclosed. Articles including metallic articles processed according to the methods and/or devices taught herein also are disclosed. | 03-22-2012 |
Stefan Einar Stefansson, Hafnarfjordur IS
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20090035332 | PHARMACEUTICAL FORMULATION - This invention relates to a stable pharmaceutical formulation containing olanzapine. The composition comprises olanzapine or a pharmaceutically acceptable salt thereof, and one or more suitable pharmaceutical excipients, wherein the composition is coated with a coating comprising polyvinyl alcohol. | 02-05-2009 |
20090221560 | Pharmaceutical Formulation - This invention relates to a stable pharmaceutical formulation containing olanzapine. The composition comprises olanzapine or a pharmaceutically acceptable salt thereof, one or more suitable pharmaceutical excipients and a compound of formula (I) and/or a compound of formula (II): or a pharmaceutically acceptable salt thereof. | 09-03-2009 |
Stefan Orn Stefansson, Hafnarfjordur IS
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20150328033 | ORTHOPEDIC DEVICE FOR TREATING COMPLICATIONS OF THE HIP - An orthopedic device is provided for treating complications of the hip and has means for trochanter compression, pelvis support, lumbar compression, variously directed straps, and thigh support. The trochanter compression and an internal/external rotation strap provide pain relief through compression and skin protection, unloading of joints through compression and sealing, and unloading by load transfer. Means for adjustably dosing of straps enables pain management and ease of use. | 11-19-2015 |
20150328034 | ORTHOPEDIC DEVICE FOR TREATING COMPLICATIONS OF THE HIP - An orthopedic device comprises a hip plate, a first strut defining an anatomical curvature between first and second ends, and a second strut having a first end slidably received by the hip plate. A hinge couples the first and second struts to one another at the first end of the first strut and the second end of the second strut, and is arranged to provide adjustable abduction ranging from a plurality of angles. A thigh cuff connects to the second end of the first strut. | 11-19-2015 |
Steingrimur Stefansson, Rockville, MD US
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20140335629 | GLYCATED PROTEIN MEASUREMENT SENSOR AND PORTABLE GLYCATED PROTEIN MEASUREMENT APPARATUS INCLUDING SAME - Disclosed are a glycated protein measurement sensor and a portable glycated protein measurement apparatus. The glycated protein measurement sensor includes: a sensing film ( | 11-13-2014 |
Steingrimur Stefansson, Gaithersburg, MD US
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20110039267 | Sample Preparation And Detection Of Analytes Using Silica Beads - This invention provides methods for concentration of analyte from biological sample, or various liquid samples and methods for identification of the analyte. The method includes providing silica beads conjugated with analyte recognition element for concentration of analyte from sample, packaging the beads into a cartridge, and attaching the cartridge to a sample holder. After the analyte concentration, additional steps can be implemented to identify the analyte to provide visual positive/negative, qualitative or quantitative results. Another exemplary embodiment of the present invention provides a system for concentration of analyte from biological sample or other various liquid samples using silica beads. According to an exemplary implementation, the system includes a cartridge comprising silica beads conjugated with analyte recognition element to concentrate at least one analyte from the sample, and a sample holder having the cartridge attached thereto. A sample is passed through the cartridge. | 02-17-2011 |
Thorleifur Stefansson, Reykjavik IS
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20140207040 | ORTHOPEDIC DEVICE FOR TREATING COMPLICATIONS OF THE HIP - An orthopedic device is provided for treating complications of the hip and has means for trochanter compression, pelvis support, lumbar compression, variously directed straps, and thigh support. The trochanter compression and an internal/external rotation strap provide pain relief through compression and skin protection, unloading of joints through compression and sealing, and unloading by load transfer. Means for adjustably dosing of straps enables pain management and ease of use. | 07-24-2014 |
20140207041 | ORTHOPEDIC DEVICE FOR TREATING COMPLICATIONS OF THE HIP - An orthopedic device is provided for treating complications of the hip and has means for trochanter compression, pelvis support, lumbar compression, variously directed straps, and thigh support. The trochanter compression and an internal/external rotation strap provide pain relief through compression and skin protection, unloading of joints through compression and sealing, and unloading by load transfer. Means for adjustably dosing of straps enables pain management and ease of use. | 07-24-2014 |
20140214016 | Orthopedic Device Having Detachable Components for Treatment Stages and Method for Using the Same - An orthopedic device has detachable components for treatment stages of an injury or surgical procedure. The orthopedic device is arranged as a protective functional support for regeneration of knee cartilage after surgical repair procedures, and includes a flexion control kit and a wrap-around liner sleeve. | 07-31-2014 |
Thorleifur Stefansson, Akureyri IS
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20150328033 | ORTHOPEDIC DEVICE FOR TREATING COMPLICATIONS OF THE HIP - An orthopedic device is provided for treating complications of the hip and has means for trochanter compression, pelvis support, lumbar compression, variously directed straps, and thigh support. The trochanter compression and an internal/external rotation strap provide pain relief through compression and skin protection, unloading of joints through compression and sealing, and unloading by load transfer. Means for adjustably dosing of straps enables pain management and ease of use. | 11-19-2015 |
20150328034 | ORTHOPEDIC DEVICE FOR TREATING COMPLICATIONS OF THE HIP - An orthopedic device comprises a hip plate, a first strut defining an anatomical curvature between first and second ends, and a second strut having a first end slidably received by the hip plate. A hinge couples the first and second struts to one another at the first end of the first strut and the second end of the second strut, and is arranged to provide adjustable abduction ranging from a plurality of angles. A thigh cuff connects to the second end of the first strut. | 11-19-2015 |