Patent application number | Description | Published |
20090069429 | Compositions Comprising Alpha-Ketoglutarate and Their Use for Modulating Muscle Performance - This invention relates to a composition comprising Alpha-ketoglutarate (AKG) for modulating muscle performance in a mammal including a human being. Also contemplated is a method for modulating muscle performance in a vertebrate, including mammal and bird, and the manufacture of a composition for the prevention, alleviation or treatment of muscle performance in said vertebrate. | 03-12-2009 |
20090208597 | HEAT PROCESSED VEGETABILIC FIBER PREPARATION AND ITS USE AS INHIBITOR OF THE EFFECTS OF CARCINOGENIC SUBSTANCES IN HUMANS OR ANIMALS - The present inventions relates to a vegetabilic, preferably potato, fiber preparation and fractions thereof for use as a supplement, a functional food, a functional mix, a pro health product and a pharmaceutical composition; it further relates to a food additive, and a food product, a feed additive and a feed product, a beverage, a supplement, a functional mix, a functional food, a health food and a pharmaceutical composition for inhibition of the effects of a dietary carcinogenic substance in humans and animals; and for inhibition of the development of neoplasma upon exposure of a human or animal for a dietary carcinogenic substance. Further it relates to a medicament, and its uses for the manufacture of a medicament for inhibition of the effects of a dietary carcinogenic substance in humans and animals; and for inhibition of the development of neoplasma upon exposure of a human or animal for a dietary carcinogenic substance. Still further it relates to a method of producing such a vegetabilic, preferably potato, fiber preparation and fractions thereof. | 08-20-2009 |
20100069498 | USE OF ALPHA-KETOGLUTARIC ACID FOR THE TREATMENT OF HIGH PLASMA GLUCOSE CONDITION - A method for improving adsorption of amino acids in a vertebrate, including mammal and bird, is included. The method comprises administering to a vertebrate, including mammal and bird, in a sufficient amount and/or at a sufficient rate to enable a desired effect, AKG, AKG derivates or metabolites, AKG analogues or mixtures thereof. Also contemplated is a method for decreasing adsorption of glucose in a vertebrate, including mammal and bird, comprising administering to the vertebrate, including mammal and bird, in the need thereof, AKG, AKG derivates or metabolites, AKG analogues or mixtures thereof, for decreasing glucose adsorption as well as compositions for use in treatment. | 03-18-2010 |
20100222282 | METHOD OF DIAGNOSIS AND METHOD OF TREATMENT - The present invention relates to a method for diagnosing higher susceptibility for diseases and conditions associated with low levels of AKG in a human or animal comprising the following steps: a) obtaining a biological sample from said human or animal; b) measuring the alpha-ketoglutaric acid (AKG) level in the biological sample; and c) comparing said measured AKG level with normal average AKG levels, wherein a level of AKG in said sample lower than an average level is indicative of a higher susceptibility for various diseases. Further the invention relates to a use of a substance comprising at least one member selected from the group consisting of AKG and derivates, metabolites, analogues or salts thereof for the manufacture of a pharmaceutical preparation or a food or feed supplement for the treatment or prophylaxis of diseases and conditions associated with low levels of AKG in a human or animal with low levels of AKG compared with normal average AKG levels. | 09-02-2010 |
20110039935 | USE OF PHARMACOLOGICALLY ACTIVE CHEMICAL COMPOUNDS - The present invention relates to the new use of alpha-ketoglutarate, amides, and salts and mixtures thereof for the manufacture of a pharmaceutical preparation or a food or feed supplement for the in vivo therapeutic improvement of blood vessel elasticity, in particular arterial elasticity in a subject in need thereof. Improving the blood vessel elasticity may be used in the for the treatment and/or prophylaxis of hypertension, pulmonary arterial hypertension, cardiovascular disease, retinal vascular disease, heart failure, atherosclerosis, ventricular hypertrophy, stroke, arterial aneurysm, kidney failure, nephrosclerosis and diseases related to hypertension. | 02-17-2011 |
20110082086 | MEDICAMENT FOR USE IN CONNECTION WITH CARTILAGE IMPAIRMENT - Use of a substance for treating joint medical conditions. The use includes the use of alpha-ketoglutarate acid. | 04-07-2011 |
20110105617 | METHOD FOR TREATMENT OF NEOPLASTIC DISEASES WITH ALPHA-KETO GLUTARATE AND/OR SALTS THEREOF - A method for treatment or prophylaxis of neoplastic diseases includes administering an antineoplastic preparation to a subject in need thereof. The active component of the antineoplastic preparation is alpha-ketoglutarate and/or a salt of alpha-ketoglutarate. | 05-05-2011 |
Patent application number | Description | Published |
20090238895 | NUTRITIONAL AND/OR PHARMACEUTICAL PREPARATION FOR USE IN PROPHYLAXIS AND TREATMENT OF DISTURBANCES IN MICROELEMENTS ABSORPTION FROM THE ALIMENTARY CANAL - The invention dissolves the problem of the pharmaceutical preparation being a factor stimulating the absorption of microelements. The essence of the invention is that the preparation contains alpha-keto-glutarate or/and glutamine or/and glutamate or/and ornithine of alpha-keto-glutarate, dipeptide of glutamine and other amino acids or/and tripeptides of glutamine and other amino acids or/and glutamate with other amino acid or/and salts of alpha-keto-glutarate or/and glutamine or/and glutamate or/and ornithine of alpha-keto-glutarate, dipepetides of glutamine or glutamate with other amino acid in a dose 0.01-0.5 g/kg/day and administered orally stimulates the absorption of iron, zinc, copper, manganese, strontium, calcium, phosphorus and other microelements from the alimentary canal to the blood ensuring proper—physiological—curative level of these compounds in the blood of people and animals. | 09-24-2009 |
20090312427 | Medicament for Use in Connection With Cartilage Impairment - Use of a substance for treating medical joint conditions, e.g. arthrosis, rheumatoid arthritis and cartilage impairment. The use includes the use of alpha-ketoglutaric acid, glutamine or glutamic acid, as well as salts, amides, di- or tripeptides of the mentioned substances. | 12-17-2009 |