Staunton
Claire Staunton, Co. Dublin IE
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20100167253 | Surgical training simulator - A surgical simulator is disclosed. The simulator includes at least one tracking system configured to track movement within a body form, including movement of an instrument located partially within the body form, and a computer receiving data from the tracking system and outputting data to a display. A display displays a virtual background including a virtual image of at least a portion of the instrument, virtual movement of the instrument, and a virtual image of at least one organ. The simulator also includes a physical model corresponding to the at least one organ and located within the body form, the physical model providing haptic feedback when contacted by the instrument. | 07-01-2010 |
Darragh Staunton, Kochel Am See DE
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20120145500 | SYSTEM AND METHOD FOR PROVIDING POWER TO A MOVING ELEMENT - A system and method for providing power to a plurality of moving elements in a transport system that include: tracking a position of each of the plurality of moving elements in the transport system; and selectively operating a power system provided to the transport system based on the position of each of the plurality of the moving element such that power is independently transferred to each of the plurality of moving elements. In another embodiment, the system and method include: adapting the plurality of moving elements to receive power from a drive component used to drive the plurality of moving elements along the transport system; and controlling the drive component to provide power to the plurality of moving elements, and, in particular, while the moving elements are moving. | 06-14-2012 |
20130084157 | SYSTEM AND METHOD FOR PROVIDING VACUUM TO A MOVING ELEMENT - A system for providing vacuum to a moving element of a transport system, the system includes: a vacuum chamber on the moving element for storing vacuum; a vacuum source; a vacuum inlet provided on the vacuum chamber and for connection to the vacuum source; and a vacuum outlet in communication with the vacuum chamber and positioned on the moving element. The vacuum source may be provided on and travel with the moving element or on the transport system and periodically engage with the vacuum chamber. Where the vacuum source is provided on the moving element, a vacuum chamber may not be required. Further, the vacuum source may be driven by electrical energy and/or mechanical energy in various configurations. | 04-04-2013 |
Darragh Staunton, Cambridge DE
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20100276255 | MULTI-MODE SCROLL CAM CONVEYOR SYSTEM - A modular multi-mode conveyor system comprising: at least one linear drive track section configured such that moving elements are independently controlled and moved along the track section; and at least one mechanical drive track section having the same configuration as the linear drive track section but wherein the linear drive is replaced with a scroll cam drive system and moving elements are controlled and moved along the track section by the scroll cam drive system. The scroll cam conveyor system comprising: a scroll cam including: a cylindrical cam; a plurality of cam grooves formed on the cylindrical cam; a drive system for rotating the scroll cam; and a moving element comprising: a plurality of cam followers, wherein the plurality of cam grooves are configured to contact with respective ones of the plurality of cam followers to move the moving element. | 11-04-2010 |
Donald E. Staunton, Kirkland, WA US
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20090081239 | Humanized PAI-1 Antibodies - The present application relates to compositions of humanized anti-PAI-1 antibodies and antigen-binding fragments thereof which convert PAI-1 to its latent form. One aspect relates to antibodies having one or more modifications in at least one amino acid residue of at least one of the framework regions of the variable heavy chain, the variable light chain or both. Another aspect relates to antibodies which bind and neutralize PAI- | 03-26-2009 |
20090136500 | Humanized PAI-1 Antibodies - The present application relates to compositions of humanized anti-PAI-1 antibodies and antigen-binding fragments thereof which convert PAI-1 to its latent form. One aspect relates to antibodies having one or more modifications in at least one amino acid residue of at least one of the framework regions of the variable heavy chain, the variable light chain or both. Another aspect relates to antibodies which bind and neutralize PAI-1 by converting PAI-1 to its latent form or increasing proteolytic cleavage. Another aspect relates to the use of humanized antibodies which inhibit or neutralize PAI-1 for the detection, diagnosis or treatment of a disease or condition associated with PAI- | 05-28-2009 |
20100254979 | Humanized PAI-1 Antibodies and Uses Thereof - The present application relates to compositions of humanized anti-PAI-1 antibodies and antigen-binding fragments thereof which convert PAI-1 to its latent form. One aspect relates to antibodies having one or more modifications in at least one amino acid residue of at least one of the framework regions of the variable heavy chain, the variable light chain or both. Another aspect relates to antibodies which bind and neutralize PAI-1 by converting PAI-1 to its latent form or increasing proteolytic cleavage. Another aspect relates to the use of humanized antibodies which inhibit or neutralize PAI-1 for the detection, diagnosis or treatment of a disease or condition associated with PAI-1 or a combination thereof. | 10-07-2010 |
Doug Staunton, Kalamazoo, MI US
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20140249531 | TOOL WITH BIOABSORBABLE MATERIAL FOR INTRAOPERATIVE USE - A surgical system for performing a surgical procedure includes a machining tool and a stationary tool. The machining tool has a first contact surface having a hardness. The stationary tool has a second contact surface at least partially formed of a magnesium alloy. The second contact surface is biocompatible and bioabsorbable, and has a hardness. The hardness of the first contact surface is greater than the hardness of the second contact surface. | 09-04-2014 |
Douglas Staunton, Texas Township, MI US
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20120022551 | DELIVERY ASSEMBLY FOR PERCUTANEOUSLY DELIVERING AND DEPLOYING AN ELECTRODE ARRAY AT A TARGET LOCATION, THE ASSEMBLY CAPABLE OF STEERING THE ELECTRODE ARRAY TO THE TARGET LOCATION - An electrode array and a delivery assembly. The array is wrapped around a flexible core part of the delivery assembly. A sheath, also part of the delivery assembly, is disposed over the array and core. Steering cables extend through the core or sheath. Once the delivery assembly-encased array is inserted in the body, the combination is advanced to the tissue over which the array is to be deployed. By pulling on the steering cables the array and assembly are steered into position. Once the array is in position, the sheath is retracted, the array deploys over the target tissue. | 01-26-2012 |
Douglas Staunton, Kalamazoo, MI US
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20110077660 | FOLDABLE, IMPLANTABLE ELECTRODE ASSEMBLY AND TOOL FOR IMPLANTING SAME - An electrode array assembly with a frame that is foldable or bendable on which electrodes are disposed. The frame includes laterally spaced apart bridges. Tabs extend laterally outwardly from the bridges Electrodes are disposed on the tabs. Beams, also part of the frame, extend between the laterally adjacent bridges. The frame can be folded around the beams so as to cause the laterally spaced bridges to at least partially overlap. When the beams are so bent, the electrode carrying tabs extend beyond the bent beams. | 03-31-2011 |
Douglas A. Staunton, Kalamazoo, MI US
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20150094736 | System and Method of Controlling a Robotic System for Manipulating Anatomy of a Patient During a Surgical Procedure - System and methods of controlling a robotic system for manipulating anatomy of a patient during a surgical procedure include applying a force to the anatomy to generate a response by the anatomy. The response of the anatomy is measured and a characteristic of the anatomy is calculated based on the response. An instrument is autonomously controlled in relation to the anatomy based on the calculated characteristic. | 04-02-2015 |
Douglas A. Staunton, Texas Township, MI US
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20100063568 | IMPLANTABLE ELECTRODE ARRAY ASSEMBLY WITH EXTRACTION SLEEVE/TETHER - An implantable electrode array including a carrier on which plural electrodes are disposed. Also disposed on the carrier is an array antenna over which signals are wirelessly received. A tether is connected to the carrier. A tether antenna is attached to the tether. After the electrode array is implanted, during a trial period instructions and power are transmitted to the array antenna over the tether antenna. If the trial is successful, the tether is disconnected from the electrode array. If the trial is not successful and extraction of the array is necessary, extraction is accomplished by pulling on the tether. Electrode array removal may be facilitated by the pulling of the array into an extraction tube disposed over the tether. | 03-11-2010 |
20120203246 | IMPLANTABLE ELECTRODE ARRAY ASSEMBLY WITH EXTRACTION SLEEVE/TETHER - An implantable electrode array including a carrier on which plural electrodes are disposed. Also disposed on the carrier is an array antenna over which signals are wirelessly received. A tether is connected to the carrier. A tether antenna is attached to the tether. After the electrode array is implanted, during a trial period instructions and power are transmitted to the array antenna over the tether antenna. If the trial is successful, the tether is disconnected from the electrode array. If the trial is not successful and extraction of the array is necessary, extraction is accomplished by pulling on the tether. Electrode array removal may be facilitated by the pulling of the array into an extraction tube disposed over the tether. | 08-09-2012 |
20140121674 | ASSEMBLY FOR PERCUTANEOUSLY INSERTING AN IMPLANTABLE MEDICAL DEVICE, STEERING THE DEVICE TO A TARGET LOCATION AND DEPLOYING THE DEVICE - An assembly for implanting a medical device such as an electrode array. The assembly includes a sheath that is disposed over the medical device and a core that supports the device. The sheath and core are connected to, respectively, first and second slides in a handpiece. An single actuator first moves one slide, typically the slide to which the sheath is attached. Once the first slide at least partially displaced both slides are moved to simultaneously retract the sheath and core away from the implantable medical device. The assembly includes a steering assembly for steering the sheath and implantable medical device. Some of the components forming the steering assembly are disposed on at least one of the slides. Tensioners prevent the steering cables of the steering assembly from being exposed to excessive force. | 05-01-2014 |
20150094734 | ELECTRODE ARRAY AND DEPLOYMENT ASSEMBLY INCLUDING AN ELECTRODE ARRAY THAT IS FOLDED INTO A CANNULA THAT IS NARROWER IN WIDTH THAN THE ARRAY - An electrode array assembly with a frame that is foldable or bendable on which electrodes are disposed. The frame includes laterally spaced apart bridges. Tabs extend laterally outwardly from the bridges Electrodes are disposed on the tabs. Beams, also part of the frame, extend between the laterally adjacent bridges. The frame can be folded around the beams so as to cause the laterally spaced bridges to at least partially overlap. When the beams are so bent, the electrode array can be disposed in an access cannula that has a diameter less than the width of the unfolded array. | 04-02-2015 |
Douglas Alan Staunton, Kalamazoo, MI US
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20110160723 | BIPOLAR CANNULA FOR USE WITH AN ELECTRODE ASSEMBLY HAVING A SEPARATE SUPPLY ELECTRODE - An electrosurgical system preferably used for denervation procedures of nerve tissue has a control unit and a pluggable electrode assembly. The electrode assembly has a preferably disposable cannula and a preservable supply electrode assembly. The cannula has a tubular body that projects axially from a preferably pointed distal end for piercing tissue to a proximal end engaged to a first coupling assembly of the cannula. The body carries a first contact exposed directly to the nerve tissue and connected electrically to a terminal of the first coupling assembly. The supply electrode assembly has a second coupling assembly and a supply electrode that projects axially and removably into a through-bore of the body when the tool is in an operating state. The second coupling assembly carries a terminal that abuts the first coupling assembly when the coupling assemblies are mated. Preferably the supply electrode carries a temperature sensor for temperature measurement of the targeted tissue and processing by the control unit. Preferably, the electrode assembly also includes a stylet having a rod that fits into the through-bore of the body when the supply electrode assembly is removed and the tool is in a tissue penetrating state. | 06-30-2011 |
20140276949 | End Effector of a Surgical Robotic Manipulator - An end effector of a surgical robotic manipulator includes a removeable cutting accessory. The cutting accessory includes a cutting tip and a shaft extending along an axis. A drive member is configured to rotatably drive the shaft of the cutting accessory. An actuator is coupled to the drive member for rotatably driving the drive member. A clutch assembly is supported by and is selectively rotatable relative to the drive member and receives the shaft of the cutting accessory along the axis of the shaft for selectively locking the shaft to the drive member. | 09-18-2014 |
Edward Staunton, East Yorkshire GB
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20110160116 | IMPROVED HARD SURFACE CLEANING COMPOSITIONS - An aqueous liquid acidic hard surface cleaning composition having a pH of about 2-4 which necessarily comprises: an acid constituent, which is preferably an organic acid constituent, and especially preferably acetic acid, at least one nonionic surfactant, and especially preferably wherein the nonionic surfactants are derived from Guerbet alcohols; an organic solvent constituent which comprises at least one glycol ether solvent, preferably a glycol ether solvent; a sequestering polymer constituent; optionally a cosurfactant constituent, including one or more anionic, cationic, amphoteric or zwitterionic surfactants; optionally one or more further constituents selected coloring agents, fragrances and fragrance solubilizers, viscosity modifying agents including one or more thickeners, pH adjusting agents and pH buffers including organic and inorganic salts, optical brighteners, opacifying agents, hydrotropes, abrasives, and preservatives, as well as other optional constituents known to the art; and the balance, water, wherein water comprises at least 80% wt. of the composition. | 06-30-2011 |
Ion Leslie Staunton, Queensland AU
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20130340320 | METHOD AMD DEVICE FOR ATTRACTING AND BAITING TERMITES - A kit of termite detector units may be used by a homeowner or a business owner in a commercial environment to form an effective protective barrier or boundary around the property with the “X”s illustrating typical placement positions detector units. The units are placed in locations where termites might be anticipated and typically the units can be placed at two to five meter spacings, although in some cases they may be spaced even further apart. This is because these units are on a large concrete area and they are placed at construction joints since the termites are more likely to travel along the joint as the line of least resistance they will be intercepted by the detector. Bait units may then be applied to infested detectors in an effort to kill the termite colony. | 12-26-2013 |
James Staunton, Cambridge GB
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20080287483 | Polyketides and Their Synthesis and Use - The rapamycin gene cluster is an example of a gene cluster which includes a gene (rapL) leading to the formation of a precursor compound (pipecolic acid, in this case) which is required for inclusion in the larger product (rapamycin) produced by the enzymes encoded by the cluster. We have produced a mutant strain containing a rapamycin gene cluster in which the rapL gene is disabled. The strain does not naturally produce rapamycin but does so if fed with pipecolic acid. By feeding with alternative carboxylic acids we have produced variants of rapamycins. Tests have shown biological activity. | 11-20-2008 |
20090104666 | Hybrid Glycosylated Products and Their Production and Use - The present invention relates to hybrid glycosylated products, and in particular, to natural products such as polyketides and glycopeptides, and to processes for their preparation. The invention is particularly concerned with recombinant cells in which a cloned microbial glycosyltransferase can be conveniently screened for its ability to generate specific glycosylated derivatives when supplied with polyketide, peptide, or polyketide-peptides as substrates. The invention demonstrates that cloned glycosyltransferases when rapidly screened for their ability to attach a range of activated sugars to a range of exogenously supplied or endogenously generated aglycone templates, show a surprising flexibility towards both aglycone and sugar substrates, and that this process allows the production of glycosylated polyketides in good yield. This overcomes the problem not only of supplying novel sugar attachments to individual polyketides, including polyketides altered by genetic engineering, but also of increasing the diversity of polyketide libraries by combinatorial attachment of sugars. | 04-23-2009 |
Jane Staunton, Roslindale, MA US
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20110224128 | METHODS AND COMPOSITIONS FOR TREATMENT OF MUSCULAR DYSTROPHY - The invention features methods, compositions, and kits useful for the treatment of muscular dystrophy, e.g., Duchenne muscular dystrophy, in a patient. | 09-15-2011 |