Patent application number | Description | Published |
20090105588 | Real-Time Ultrasound Monitoring of Heat-Induced Tissue Interactions - The present invention includes an apparatus, method and system for monitoring and controlling radiation therapy, the system including a radiative source that emits energy that enters a tissue and is absorbed at or a near a target site in the tissue to heat the tissue; an ultrasound transmitter directed at the target site, wherein the ultrasound transmitter emits ultrasound signals to the tissue that has been heated by the radiative source; an ultrasound receiver directed at the target site, wherein the ultrasound receiver receives ultrasound signals emitted from the ultrasound transmitter and reflected from the tissue that has been heated by the radiative source; and a signal processor that processes the received ultrasound signal to calculate a tissue composition scan or tissue temperature scan. | 04-23-2009 |
20100028261 | Molecular Specific Photoacoustic Imaging - Methods relating to photoacoustic imaging of biological tissue are provided. One such method comprises contacting a biological tissue with a bioconjugate and irradiating the bioconjugate so as to generate an acoustic wave, wherein the bioconjugate comprises a nanoparticle and a moiety capable of selectively coupling a molecular marker. Suitable moieties include, among other things, epithelial growth factor receptor (EGFR). | 02-04-2010 |
20120125107 | TEMPERATURE DEPENDENT PHOTOACOUSTIC IMAGING - Methods and systems relating to temperature dependent photoacoustic imaging are provided. | 05-24-2012 |
20120197114 | NANOCARRIERS FOR IMAGING AND THERAPY APPLICATIONS - Nanocarriers and methods of preparation and use of nanocarriers are presented. In some embodiments, a nanocarrier composition comprises an organic liquid comprising a plurality of nanoparticles dispersed therein; and a coating material disposed around the exterior surface of the organic liquid. Biological tissue may be imaged or treated by coming into contact with a nanocarrier composition, and, at least in some embodiments, irradiated. | 08-02-2012 |
20120253180 | COMBINED ULTRASOUND AND PHOTOACOUSTIC IMAGING OF METAL OBJECTS - Methods of combined ultrasound and photoacoustic imaging are provided. In some embodiments, the methods may be used to determine the location or positioning of a metal object in a sample. In other embodiments, the methods may be used to determine the composition of a sample surrounding a metal object. Other methods are also provided. | 10-04-2012 |
20120271170 | CATHETER FOR INTRAVASCULAR ULTRASOUND AND PHOTOACOUSTIC IMAGING - A design and a fabrication method for an intravascular imaging and therapeutic catheters for combined ultrasound, photoacoustic, and elasticity imaging and for optical and/or acoustic therapy of hollow organs and diseased blood vessels and tissues are disclosed in the present invention. The invention comprises both a device—optical fiber-based intravascular catheter designs for combined IVUS/IVPA, and elasticity imaging and for acoustic and/or optical therapy—and a method of combined ultrasound, photoacoustic, and elasticity imaging and optical and/or acoustic therapy. The designs of the catheters are based on single-element catheter-based ultrasound transducers or on ultrasound array-based units coupled with optical fiber, fiber bundles or a combination thereof with specially designed light delivery systems. One approach uses the side fire fiber, similar to the one utilized for biomedical optical spectroscopy. The second catheter design uses the micro-optics in the manner of a probe for optical coherent tomography. | 10-25-2012 |
20130023714 | Medical and Imaging Nanoclusters - In one embodiment the present invention discloses a nanocluster or a nanorose composition comprising two or more closely spaced nanoparticles each comprising one or more metals, metal oxides, inorganic substances, or a combination thereof and one or more stabilizers. The stabilizers are in contact with the two or more closely spaced nanoparticles to form a nanocluster composition in which the inorganic weight percentage is greater than 50% and the average size is below 300 nm, and the nanocluster composition has magnetic properties, optical properties or a combination of both. | 01-24-2013 |
20130096422 | INTERVENTIONAL PHOTOACOUSTIC IMAGING SYSTEM - An interventional photoacoustic imaging system and method for cancer treatment comprises an optical source for applying laser energy to optically excite a treatment area, a needle, ablation tool or catheter for inserting the optical source into a body of a patient adjacent the treatment area, and an ultrasonic transducer for detecting the acoustic waves. A processor receives the raw data from the ultrasound system and processes it to thereby form a photoacoustic image of the tissue in real time. As such, image formation may be performed preoperatively, intraoperatively, and postoperatively. | 04-18-2013 |
20130338498 | Catheter for Intravascular Ultrasound and Photoacoustic Imaging - The present invention includes a method of imaging and treating a target tissue without the need to occlude or dilute luminal blood in a subject by a combination of intravascular ultrasound and photoacoustic imaging by irradiating the target tissue with electromagnetic radiation at a single wavelength. | 12-19-2013 |
20140157901 | COMBINED ULTRASOUND AND PHOTOACOUSTIC IMAGING OF METAL OBJECTS - Methods of combined ultrasound and photoacoustic imaging are provided. In some embodiments, the methods may be used to determine the location or positioning of a metal object in a sample. In other embodiments, the methods may be used to determine the composition of a sample surrounding a metal object. Other methods are also provided. | 06-12-2014 |
20140335024 | NANOCARRIERS FOR IMAGING AND THERAPY APPLICATIONS - Nanocarriers and methods of preparation and use of nanocarriers are presented. In some embodiments, a nanocarrier composition comprises an organic liquid comprising a plurality of nanoparticles dispersed therein; and a coating material disposed around the exterior surface of the organic liquid. Biological tissue may be imaged or treated by coming into contact with a nanocarrier composition, and, at least in some embodiments, irradiated. | 11-13-2014 |
20150087955 | MULTI-WAVELENGTH PHOTOACOUSTIC CHARACTERIZATION AND THERMOGRAPHIC IMAGING - The present disclosure relates to a method comprising imaging a tissue with multi-wavelength photoacoustic imaging, to provide a visualization, characterization and/or thermographic imaging of the tissue. | 03-26-2015 |