Sorge, US
Anthony Sorge, Rancho Santa Fe, CA US
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20090042296 | TRANSFECTION READY EUKARYOTIC CELLS - Described herein are frozen populations of transfection ready competent eukaryotic cells, transfection kits comprising the frozen populations of transfection ready competent cells, and methods of using the same. | 02-12-2009 |
20110045524 | TRANSFECTION READY EUKARYOTIC CELLS - Described herein are frozen populations of transfection ready competent eukaryotic cells, transfection kits comprising the frozen populations of transfection ready competent cells, and methods of using the same. | 02-24-2011 |
Gregory Walter Sorge, Waukesha, WI US
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20150101580 | SYSTEM AND METHOD FOR CONTROL OF EXHAUST GAS RECIRCULATION (EGR) UTILIZING PROCESS TEMPERATURES - A system includes a reciprocating internal combustion engine with one or more reaction zones configured to receive a charge flow that is configured to react within the one or more reaction zones, thereby forming an exhaust gas flow, and a controller. The charge flow includes an oxidant flow, a fuel flow, and a recirculated portion of the exhaust gas flow. The controller is configured to control a ratio of the recirculated portion of the exhaust gas flow to a fuel mixture. The controller controls the ratio based at least in part on a first temperature, a second temperature of the charge flow, and a third temperature of the recirculated portion of the exhaust gas flow. The fuel mixture includes the oxidant flow and the fuel flow. The first temperature includes one or any combination of a sensed temperature of the oxidant flow, the fuel flow, or the fuel mixture. | 04-16-2015 |
20150377161 | SYSTEMS AND METHODS FOR ENGINE CONTROL INCORPORATING FUEL PROPERTIES - A method includes receiving a fuel composition analysis, deriving a fuel index based on the fuel composition analysis, deriving a control adjustment for a gas engine based on the fuel index, and applying the control adjustment to an actuator of the gas engine. | 12-31-2015 |
Jason Karl Sorge, Geneseo, NY US
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20160052767 | Container Filling System and Valve for Same - A container filling valve may include a shuttle and a drive sleeve that are magnetically coupled. Movement of the drive sleeve may move the shuttle from a position in which the filling valve is closed to a position in which the filling valve is open. A container handling arm may include a distal end configured to hold a container and a proximal end that includes a load cell. A low flow setpoint system may be configured to arrest closing of a filling valve when that filling valve is partially closed. A pressure control system may be configured to maintain a desired pressure in a reservoir or in a flow path from that reservoir. A product recirculation system may be configured to adjust flow rate in the product recirculation system. | 02-25-2016 |
Jeff Sorge, Westminster, CO US
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20130182462 | LINEAR SYNCHRONOUS RECTIFIER DRIVE CIRCUIT - A drive circuit arranged to drive a synchronous rectifier of a power converter includes a differential amplifier stage connected to the synchronous rectifier and arranged to supply a drive signal to the synchronous rectifier to turn the synchronous rectifier on and off and a high voltage blocking stage connected between the synchronous rectifier and the differential amplifier stage. The differential amplifier stage is arranged such that a voltage level of the drive signal depends on a load of the power converter. | 07-18-2013 |
Joseph Sorge, Wilson, WY US
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20100075307 | ANALYTE DETECTION ASSAYS - The present invention provides methods, kits and compositions for the detection of an analyte. In the methods of the invention, a binding molecule coupled to a first polymerase is incubated with a modified polynucleotide template to form a copy of the modified polynucleotide template without any modified nucleotides. The unmodified copy is detected in a second amplification/primer extension reaction using a second polymerase that is unable to amplify the modified polynucleotide template. Detection of the unmodified copy is indicative of the presence and/or amount of the analyte in the sample. In place of the binding molecule coupled to a first polymerase, a pair of analyte-specific probes can also be used. The first analyte specific probe comprises a first binding moiety and a first portion of a first polymerase and the second analyte specific probe comprises a second binding moiety and a second portion of the first polymerase. When the binding moieties are bound to the analyte the first and second portions of the polymerase interact to form a functional polymerase complex that is used to form a copy of the modified polynucleotide template without any modified nucleotides. | 03-25-2010 |
Joseph A. Sorge, Delmar, CA US
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20090117540 | Methods for detection of a target nucleic acid by forming a cleavage structure using an RNA polymerase - The invention relates to compositions and methods for generating a signal indicative of the presence of a target nucleic acid in a sample, where the compositions and methods include an RNA polymerase, a FEN nuclease, and a probe. | 05-07-2009 |
Joseph A. Sorge, Del Mar, CA US
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20080280291 | Compositions and methods utilizing DNA polymerases - The invention features a novel isolated Family B DNA polymerase, a | 11-13-2008 |
20090011408 | Methods for detection of a target nucleic acid by forming a cleavage structure using a reverse transcriptase - The invention relates to and methods for generating a signal indicative of the presence of a target nucleic acid in a sample. The compositions and methods include a reverse transcriptase, a nuclease, an upstream primer and downstream probe. | 01-08-2009 |
Joseph A. Sorge US
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20130122504 | Expression Levels of COL4A3BP and other Markers Correlating with Progression or Non-Progression of Bladder Cancer - Disclosed is determining expression levels of protective or harmful markers for bladder cancer prognosis; particularly, determining the expression level of COL4A3BP alone or in combination with expression levels of MBNL2, FABP4, and NEK1 or other markers where increased expression levels of these protective markers relative to a control correlates with lack of bladder cancer progression and decreased expression levels correlate with bladder cancer progression or death. Also disclosed particularly is determining the expression level of COL4A1 alone or in combination with expression levels of UBE2C, BIRC5, COL18A1, KPNA2, MSN, ACTA2, and CDC25B or other markers where increased expression levels of these harmful markers relative to a control correlates with bladder cancer progression or death and decreased expression levels correlate with lack of bladder cancer progression. Also disclosed are signatures of protective and harmful markers to predict likelihood of bladder cancer progression or non-progression. | 05-16-2013 |
Joseph A. Sorge, Wilson, WY US
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20080199935 | Compositions and methods utilizing DNA polymerases - The invention features a novel isolated Family B DNA polymerase, a | 08-21-2008 |
20080299549 | Methods and compositions for the detection of a nucleic acid by a cleavage reaction - The invention provides methods, compositions and kits for generating a signal indicative of the presence of a target nucleic acid sequence in a sample comprising forming a cleavage structure by incubating a sample comprising a target nucleic acid sequence with upstream and downstream oligonucleotides, and cleaving the cleavage structure with a nuclease to generate a signal. The presence of a detectable signal is indicative of the presence of a target nucleic acid sequence and a non-invasive cleavage structure. | 12-04-2008 |
20090061426 | Binary signaling assay using a split-polymerase - The present invention provides methods, kits and compositions for the detection of an analyte. In the methods of the invention, a complex is formed between two or more analyte specific probes (ASP) and an analyte. The analyte specific probes each have a portion of a polymerase which interact to form a functional polymerase complex upon binding of the ASP to the analyte. The functional polymerase complex then generates a detectable signal which is indicative of the presence and/or amount of the analyte in the sample. | 03-05-2009 |
20130183345 | Treatment of Bladder Cancer Following Detection of Expression Levels of Certain Progression Markers - Disclosed is determining expression levels of protective or harmful markers for bladder cancer prognosis and treatment; particularly, determining the expression levels of protective markers (COL4A3BP, MBNL2, FABP4, NEK1 and SKAP2) and harmful markers (COL4A1, UBE2C, BIRC5, COL18A1, KPNA2, MSN, ACTA2, and CDC25B) and making treatment decisions in consideration of increased or decreased risk of progression based on the marker expression levels. | 07-18-2013 |
20140024027 | Methods of enriching for and identifying polymorphisms - The invention encompasses methods for enriching for and identifying a polymorphism within a nucleic acid sample either by separating a subset of a nucleic acid sample or by selectively replicating a subset of a nucleic acid sample such that the polymorphism is contained within a nucleic acid population with reduced complexity, and then identifying the polymorphism within the enriched nucleic acid sample. Methods also are disclosed for enriching for and identifying a polymorphism by contacting a nucleic acid sample that includes a subset of nucleic acid molecules having a sequence that binds to a sequence-specific binding activity with a molecule having a sequence-specific binding activity under conditions which permit specific binding, such that the subset of nucleic acid molecules bound to the activity is enriched for nucleic acid molecules having the sequence recognized by the sequence-specific binding activity, and detecting a polymorphism with respect to a reference sequence in the subset of nucleic acid molecules. | 01-23-2014 |
20140031237 | Methods of enriching for and identifying polymorphisms - The invention encompasses methods for enriching for and identifying a polymorphism within a nucleic acid sample either by separating a subset of a nucleic acid sample or by selectively replicating a subset of a nucleic acid sample such that the polymorphism is contained within a nucleic acid population with reduced complexity, and then identifying the polymorphism within the enriched nucleic acid sample. Methods also are disclosed for enriching for and identifying a polymorphism by contacting a nucleic acid sample that includes a subset of nucleic acid molecules having a sequence that binds to a sequence-specific binding activity with a molecule having a sequence-specific binding activity under conditions which permit specific binding, such that the subset of nucleic acid molecules bound to the activity is enriched for nucleic acid molecules having the sequence recognized by the sequence-specific binding activity, and detecting a polymorphism with respect to a reference sequence in the subset of nucleic acid molecules. | 01-30-2014 |
Joseph A. Sorge, Jackson, WY US
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20100248246 | METHODS OF ENRICHING FOR AND IDENTIFYING POLYMORPHISMS - The invention encompasses methods for enriching for and identifying a polymorphism within a nucleic acid sample either by separating a subset of a nucleic acid sample or by selectively replicating a subset of a nucleic acid sample such that the polymorphism is contained within a nucleic acid population with reduced complexity, and then identifying the polymorphism within the enriched nucleic acid sample. Methods also are disclosed for enriching for and identifying a polymorphism by contacting a nucleic acid sample that includes a subset of nucleic acid molecules having a sequence that binds to a sequence-specific binding activity with a molecule having a sequence-specific binding activity under conditions which permit specific binding, such that the subset of nucleic acid molecules bound to the activity is enriched for nucleic acid molecules having the sequence recognized by the sequence-specific binding activity, and detecting a polymorphism with respect to a reference sequence in the subset of nucleic acid molecules. | 09-30-2010 |
Keith Marlowe Sorge, Plymouth, MN US
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20130069766 | Hand-Held Security Alarm System - A hand-held security alarm system for sounding an alarm when the system is released. The hand-held security alarm system includes a hand-held device that contains an alarm, a battery, an activation member, an activation electronic circuit, an alarming member, and a deactivation button. The activation member being biased to push away from the hand-held device by a compression spring. The activation electronic circuit being activated by an activation switch when the activation member travels a certain distance from the hand-held device. The hand-held device is maintained in the inactive state by the activation member being held against the hand-held device by a detent incorporated into the alarming member. The hand-held device is put into the armed position by sliding the alarming member so that the detent on the activation member travels past a catch on the activation member and the activation is held against the compression spring by an external force such as a hand grasping the hand-held device. The hand-held device once armed is activated by releasing the external force on the activation member so that the compression spring pushes the activation member away from the hand-held device thereby triggering the electronic circuit and causing the battery to energize the alarm causing an audible sound. The electronic circuit cannot be deactivated by pressing the activation member back towards the hand-held device but requires the application of a deactivation switch which when pushed opens the electronic circuit cutting the battery power from the alarm. The hand-held device includes a strap that can be securely attached to the body of the user so that in an attack the hand-held device stays with the user. | 03-21-2013 |
Nicholas Sorge, Bellport, NY US
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20140138915 | CARD DECK AND METHOD OF PLAYING CARD GAMES WITH SAME - A 50-card deck is provided in which the cards are equally divided between 5 suits. Moreover, each suit contains 10 cards ranging from 2 through 9 and an Ace—the 50-card deck lacks face cards. The suits may be selected from traditional card suits, colors, and other symbols. Use of the five-suit 50-card deck enhances play of traditional card games including Baccarat, Blackjack and many Poker variants by altering odds of winning. Additionally, in Poker the 50-card deck alters the ranking of winning hands. Five of a Kind is available as the highest winning hand and Royal Flush, by virtue of the deck lacking face cards, is not available. | 05-22-2014 |
20150321081 | 12-COLOR ROULETTE WHEEL, 12-COLOR PINWHEEL, AND BETTING TABLE ASSOCIATED THEREWITH - A gaming apparatus, configured as a roulette wheel, includes a circular surface rotationally anchored to a base at a central axis perpendicular to a plane of the circular surface; a plurality of indicia uniformly arranged at a periphery of the circular surface, each indicia being assigned a unique number and one of twelve colors; and a marker configured to select one of the plurality of indicia or house indicia. Another embodiment of a gaming apparatus is configured as a pinwheel including a first circular surface having a plurality of numeral indicia uniformly arranged at a periphery; and a second circular surface concentrically disposed with respect to the first circular surface. The second circular surface is configured to rotate independent of the first circular surface, and has a plurality of color indicia uniformly arranged at a periphery of the second circular surface, each indicia being assigned one of twelve colors. | 11-12-2015 |
Nicholas Sorge, Dear Park, NY US
Nicholas Sorge, Deer Park, NY US
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20080224393 | Roulette game apparatus and method - A method for arranging indicia on a game surface and on an associated roulette wheel. Indicia indicating numbers from 1 through 60 are arranged on the game surface in ascending order with half of the numbers associated with a first color and half associated with a second color. The numbers are arranged in three groups of twenty, each group having five even numbers and five odd numbers associated with each of the two colors. Indicia indicating each of the numbers are arranged on a roulette wheel such that no two adjacent numbers on the roulette wheel are associated with a same color, are disposed in a same group, are disposed in a same column, are disposed in a same row, or are disposed adjacent one another on the game surface. | 09-18-2008 |
20080258383 | Roulette game apparatus with side bet game - A roulette game including a board game surface and roulette wheel, wherein besides the traditional roulette wheel wagering opportunities, an additional novel wagering area is provided for additional “side betting.” That is, a side wagering area comprising ten individual wagering areas corresponding to a digit value 0, . . . , 9, is provided for the game board surface. A bettor may conduct a wager by placing a chip or marker on a particular digit value of the side wagering area for indicating a wager that a resulting digit of a one digit or two digit whole number roulette spin outcome will match that digit value being wagered. The payout odds for a winning side bet adheres to house advantages established for both American and European style roulette games. | 10-23-2008 |
20090283968 | ROULETTE GAME APPARATUS AND MEHTOD - A method for arranging indicia on a game surface and on an associated roulette wheel. Indicia indicating numbers from 1 through 36 are arranged on the game surface in ascending order with half of the numbers associated with a first color and half associated with a second color. The numbers are arranged in three groups of twelve, each group having three even numbers and three odd numbers associated with each of the two colors. Indicia indicating each of the numbers are arranged on a roulette wheel such that no two adjacent numbers on the roulette wheel are associated with a same color, are disposed in a same group, are disposed in a same column, are disposed in a same row, or are disposed adjacent one another on the game surface and such that each pair of numbers disposed substantially diametrically across from one another on the roulette wheel is disposed in a same group and column on the game surface. | 11-19-2009 |
20090302534 | ROULETTE GAME APPARATUS AND MEHTOD - A method for arranging indicia on a game surface and on an associated roulette wheel includes arranging indicia indicating numbers from 1 through 36 on the game surface. The numbers are arranged in ascending order with half of the numbers associated with a first color and a remaining half associated with a second color, The numbers are arranged in three groups of twelve numbers each with each group having three even numbers and three odd numbers associated with each of the two colors. Indicia indicating each of the numbers are arranged on a roulette wheel such that no two adjacent numbers on the roulette wheel are associated with a same color, are disposed in a same group, are disposed in a same column, are disposed in a same row, or are disposed adjacent one another on the game surface. | 12-10-2009 |
20120061912 | ROULETTE GAME APPARATUS AND METHOD - A Balanced Roulette game and Balanced Roulette method for arranging indicia on a Balanced Roulette Wheel game surface and on an associated Balanced Roulette wheel having indicia indicating non-house numbers from 1 through 36. A Balanced Super Roulette game and method for arranging indicia on a Balanced Super Roulette wheel game surface and on an associated Balanced Super Roulette Wheel having indicia indicating non-house numbers from 1 through 60. Each of the Balanced Roulette and Balanced Super Roulette wheels/game surfaces have indicia (number and color) arranged such that the impact of wheel Bias that affects bettor payouts for multi-number bets is reduced. | 03-15-2012 |