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Small, NY

Benjamin A. Small, New York, NY US

Patent application numberDescriptionPublished
20110052192SYSTEMS AND METHODS FOR STORING OPTICAL DATA - An optical data storage system and method of use thereof are presented. The optical data storage system includes one or more optical buffer modules connected in series. Each optical buffer module includes a cross connect. Each cross connect is connected, by a pair of inputs and outputs, to an optical data storage unit, for example, a fiber delay line, by a pair to either an optical packet network or a cross connect of a first adjacent buffer module in the series, and by a pair to a cross connect of a second adjacent buffer module in the series. The buffer module also includes a read signal output line which is connected to a read signal input line of the second adjacent buffer module for transmitting a read signal. A control module within each buffer module directs the passage of data through the cross connect.03-03-2011

Jeff Small, Rochester, NY US

Patent application numberDescriptionPublished
20080303836VIDEO DISPLAY DRIVER WITH PARTIAL MEMORY CONTROL - Partial memory control for a video display driver in which data storage is provided for storing and providing a plurality of video pixel data having selectable ones of a plurality of pixel color depths to be displayed by a plurality of video displays having a plurality of mutually distinct dimensions.12-11-2008

Jeffrey Small, Rochester, NY US

Patent application numberDescriptionPublished
20120320096GAMMA CURVE VOLTAGE GENERATION - A gamma curve voltage generator circuit comprises a first linear resistor string and a second linear resistor string. The first linear resistor string comprises resistors of a first resistor value and corresponds to a first portion of a gamma curve. A first end of the first linear resistor string is ohmically coupled to a first end of the second linear resistor string. The second linear resistor string comprises resistors of a second resistor value and corresponds to a second portion of the gamma curve. The first resistor value is different from the second resistor value.12-20-2012

Jeffrey A. Small, Rochester, NY US

Patent application numberDescriptionPublished
20120111119METHOD AND APPARATUS FOR SENSING AN INPUT OBJECT RELATIVE TO A SENSING REGION OF AN ULTRASOUND SENSOR DEVICE - A subsystem, system and method for sensing an input object relative to a sensing region of an ultrasound sensor device are disclosed herein. In one embodiment, a subsystem for sensing an input object relative to a sensing region of an ultrasound sensor device includes a circuit, a switch coupled to an output of the circuit, and an integrating capacitor coupled to the output of the circuit. The circuit has an input for receiving a resulting signal comprising positive and negative polarities, the resulting signal having effects indicative of the input object relative to the sensing region. The integrating capacitor is also coupled to a substantially constant voltage source and to the switch. The circuit is operable to output a rectified signal to the first integrating capacitor indicative of the input object relative to a sensing region.05-10-2012

Robert Small, Williamsville, NY US

Patent application numberDescriptionPublished
20100098534INTEGRAL SCROLL AND GEARBOX FOR A COMPRESSOR WITH SPEED CHANGE OPTION - The volute is cast integrally with the gearbox base to allow closer radial tolerances to be used to improve efficiency. In the preferred embodiment, compressors for multi-stage compression are assembled with intercoolers and the integral volute is cast together with the impeller housing and the lower gearbox housing and the associated intercooler. Efficiency increases of 2% or more are achievable. In multistage applications, efficiency gains in the early stages are compounded in each subsequent stage. Speed changes that change center distance between bull gear and pinion are accommodated by an offset opening in the inlet and diffuser that can line up with the impeller shaft as well as an offset opening in the fluid seal despite a pinion gear change, by reorientation and remounting of those parts.04-22-2010
20110076136GAS COMPRESSOR MAGNETIC COUPLER - Provided in some embodiments is a gas compression system that includes a gas compressor having a drive shaft, an impeller drive shaft magnetically coupled to the drive shaft, and a shroud disposed between the drive shaft and the impeller drive shaft. In other embodiments provided is method that includes magnetically coupling a first drive shaft to a second drive shaft, receiving a rotational torque at the first drive shaft, transmitting the rotational torque from the first drive shaft to the second drive shaft via the magnetic coupling, and rotating a gas compressor impeller coupled to the second drive shaft.03-31-2011

Robert Small, Horseheads, NY US

Patent application numberDescriptionPublished
20110052111MODULAR ROTOR ASSEMBLY - Portions of the drive system for a piece of rotating equipment are pre-assembled into a subassembly. The subassembly can be held together by a carrier that is fabricated to accept the components in a proper alignment so that the carrier can be installed as a unit. In the preferred embodiment the carrier becomes a gearbox housing component that is installed saving the need for individual component alignment. Using the modular approach. The modular approach allows an assembly having a single part number to apply to a given compressor unit and further allows standardization of air ends of compressors with specific impellers and inlets added to meet requirements of a specific application.03-03-2011

Robert C. Small, Williamsville, NY US

Patent application numberDescriptionPublished
20120014801DIFFUSER HAVING DETACHABLE VANES WITH POSITIVE LOCK - A system, in certain embodiments, includes a centrifugal compressor diffuser that includes an elliptical plate including multiple vane receptacles disposed about an axis of the plate and multiple detachable vanes attached to the plate. Each vane receptacle includes a first two dimensional (2D) projection along a plane of the elliptical plate and each detachable vane includes a second two dimensional (2D) projection along a base portion of the vane, where each detachable vane is disposed in a respective vane receptacle with the first and second 2D projections blocking movement of the detachable vane in at least a first axial direction relative to the elliptical plate. In certain embodiments, the first and second 2D projections may include a first tab to fit in a recess between a pair of second tabs, respectively, or vice versa. However, in other embodiments, the first and second 2D projections may include alternative mating surfaces.01-19-2012

Scott Small, Millerton, NY US

Patent application numberDescriptionPublished
20080214482Retromer-based assays and methods for treating alzheimer's disease - This invention provides a method for determining whether an agent causes an increase in the expression of a retromer complex protein. This invention further provides a method for determining whether an agent causes an increase in the activity of a retromer complex. This invention also provides a method for increasing the expression of a retromer complex protein in a cell. This invention provides a method for treating a subject afflicted with Alzheimer's disease. This invention further provides a pharmaceutical composition as well as an article of manufacture.09-04-2008

Scott A. Small, New York, NY US

Patent application numberDescriptionPublished
20090246145Imaging Correlates of Neurogenesis With MRI - This invention provides a method for treating a mammalian subject afflicted with a disorder associated with reduced neurogenesis in the subject's hippocampal dentate gyrus which comprises administering to the subject a therapeutically effective amount of a compound which increases cerebral blood volume in the subject's hippocampal dentate gyrus by a percentage greater than that by which it increases the cerebral blood volume in the subject's hippocampal CA1 region, thereby treating the subject.10-01-2009
20090253779Expression of Rbap48 in Memory and Aging and Methods Related Thereto - This invention provides a method for increasing the expression of RbAp48 protein in a eukaryotic cell comprising introducing into the cell an agent which specifically increases the expression of RbAp48 protein in the cell. This invention also provides a method for treating a subject afflicted with age-related memory decline comprising administering to the subject a therapeutically effective amount of an agent which specifically increases the expression of RbAp48 protein in the cells of the subject's brain. This invention further provides a method for determining whether an agent causes an increase in the expression of RbAp48 protein. Finally, this invention provides a method for determining whether an agent causes an increase in the activity of RbAp48 protein.10-08-2009

Patent applications by Scott A. Small, New York, NY US

Scott A. Small, Millterton, NY US

Patent application numberDescriptionPublished
20120129939POLYAMINE INHIBITORS FOR THE TREATMENT AND PREVENTION OF PARKINSON'S DISEASE - Disclosed herein are methods for treating a disease involving α-synucleic aggregation using (1) a compound which reduces the amount of polyamines in an amount effective to reduce α-synucleic aggregation; (2) a compound which inhibits polyamine synthesis in an amount effective to reduce α-synucleic aggregation; or (3) a compound which inhibits α-synucleic aggregation in an amount effective to reduce α-synucleic aggregation. Also disclosed are methods for reducing the amount of α-synucleic aggregation in a brain cell using (1) a compound which reduces the amount of polyamines in an amount effective to reduce α-synucleic aggregation; (2) a compound which inhibits polyamine synthesis in an amount effective to reduce α-synucleic aggregation; or (3) a compound which inhibits α-synucleic aggregation in an amount effective to reduce α-synucleic aggregation. Disclosed herein are also compounds which can be used in the above described methods.05-24-2012

Scott A. Small, Millerton, NY US

Patent application numberDescriptionPublished
20090005711Systems and methods for opening of the blood-brain barrier of a subject using ultrasound - A system and method for opening the blood-brain barrier in the brain of a subject is disclosed. In some embodiments, a region of the brain of a subject is targeted for opening; and a focused ultrasound beam is applied through the skull of the subject to the targeted region to open the blood-brain barrier in the brain of the subject.01-01-2009