Simonsen, DK
Adam Cohen Simonsen, Odense C DK
Patent application number | Description | Published |
---|---|---|
20100144848 | DNA CONTROLLED ASSEMBLY OF LIPID MEMBRANES - The present invention relates to detection of target nucleic acids by target nucleic acid induced liposome assembly. The invention provides oligonucleotides for use in detection and a method of detecting target nucleic acids. Other aspects of the invention are use of the oligonucleotide of the invention for detection, a kit for detection, a method of treatment comprising administrating the oligonucleotide of the invention and a pharmaceutical composition comprising the oligonucleotide of the invention. | 06-10-2010 |
Anja Hviid Simonsen, Frederiksberg DK
Patent application number | Description | Published |
---|---|---|
20110129920 | BIOMARKERS FOR ALZHEIMER'S DISEASE - The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying Alzheimer's disease status in a patient. In particular, the biomarkers of this invention are useful to classify a subject sample as Alzheimer's or non-Alzheimer's dementia or normal. The biomarkers can be detected by SELDI mass spectrometry. In addition, the invention provides appropriate treatment interventions and methods for measuring response to treatment. Certain biomarkers of the invention may also be suitable for employment as radio-labeled ligands in non-invasive imaging techniques such as Positron Emission Tomography (PET). | 06-02-2011 |
20110294865 | METHODS OF DETECTING A FRAGMENT OF NEUROSECRETORY PROTEIN VGF FOR DIAGNOSING ALZHEIMER'S DISEASE - The present invention provides a neurosecretory protein VGF peptide useful in qualifying Alzheimer's disease status in a patient. In particular, this peptide and modified forms thereof may be used to classify a subject sample as Alzheimer's disease or non-Alzheimer's disease. The peptide biomarker can be detected by SELDI mass spectrometry. | 12-01-2011 |
20130073308 | Methods of Detecting a Fragment of Neurosecretory Protein VGF for Diagnosing Alzheimer's Disease - The present invention provides a neurosecretory protein VGF peptide useful in qualifying Alzheimer's disease status in a patient. In particular, this peptide and modified forms thereof may be used to classify a subject sample as Alzheimer's disease or non-Alzheimer's disease. The peptide biomarker can be detected by SELDI mass spectrometry. | 03-21-2013 |
Bente Simonsen, Odder DK
Patent application number | Description | Published |
---|---|---|
20150150287 | COMPOSITION - There is provided a composition comprising (a) a food ingredient, the hydration of which is to be enhanced; (b) a water soluble particulate material, having an average particle size of from 10 to 1000 μm; wherein the food ingredient and the water soluble particulate material are integrated with each other. | 06-04-2015 |
Christian H. Simonsen, Ulstrup DK
Patent application number | Description | Published |
---|---|---|
20150129054 | HYDRAULIC CONTROL VALVE ASSEMBLY AND CONTROL SYSTEM FOR WATER SUPPLY NETWORKS - A modular hydraulic control valve assembly for use in a pilot-operated hydraulic control system comprises, in one embodiment, a control valve including a valve body defining a main flow passage from an inlet on a high pressure side of the control valve to an outlet on a low pressure side of the control valve, a valve member arranged in the flow passage and separating the high pressure side from the low pressure side, a control chamber comprising means for hydraulic actuation of the valve member by applying a control pressure to the control chamber so as to position the valve member between an open position and a closed position thereby adjusting a main flow through the main flow passage in response to the control pressure, a feed port for feeding fluid to the control chamber to increase the control pressure therein, a bleed port for bleeding fluid from the control chamber to decrease the control pressure therein, and a valve bonnet closing the control chamber. The assembly further comprises a feed check valve determining a feed flow direction, a bleed check valve determining a bleed flow direction, a distribution block including a common plenum, a control input in fluid communication with the common plenum, and a control output in fluid communication with the common plenum, wherein the distribution block further comprises a feed channel connecting the common plenum with the feed port via an adjustable feed constriction, and a bleed channel connecting the common plenum with the bleed port via an adjustable bleed constriction. | 05-14-2015 |
Gert Simonsen, Espergaerde DK
Patent application number | Description | Published |
---|---|---|
20100136359 | COATING COMPOSITIONS COMPRISING BISMUTH-ALLOYED ZINC - The present application discloses (i) a coating composition comprising a particulate zinc-based alloyed material, said material comprising 0.05-0.7% by weight of bismuth (Bi), the D | 06-03-2010 |
Hanne Simonsen, Struer DK
Patent application number | Description | Published |
---|---|---|
20110004151 | Treatment or Therapy Apparatus - The apparatus is arranged to supply a flow of substantially pure oxygen to a person, and comprises a source of substantially pure oxygen gas, means for release of the substantially pure oxygen gas from the source into an ambient atmosphere; and means for cooling the substantially pure oxygen gas released from the source to a temperature below that of the ambient atmosphere. The substantially pure oxygen gas when cooled by the cooling means can be allowed to sink under ambient pressure by convection into a zone including the ambient atmosphere, the zone being beneath, and in convective communication with, the cooled substantially pure oxygen gas, whereby the cooled and sunken substantially pure oxygen gas can come into contact with the skin of a person in that zone. At least one parameter (such as temperature, oxygen concentration, sound or vibration) is monitored in the zone and operation of the release means is only permitted when the parameter is in a predetermined range. | 01-06-2011 |
20110060252 | Monitoring Apparatus and Method - The apparatus for monitoring muscle contractions of a subject (for example as a check on epilepsy or Parkinson's disease) comprises: a first sensor arranged to be placed on a reference location on the body of a subject for sensing, over a prolonged period of time, a reference parameter derived from at least one of movement and electrical activity of the muscles of the body at the reference location; at least one further sensor arranged to be placed on a chosen location on a limb of a subject, for sensing, over a prolonged period of time, a monitoring parameter derived from at least one of movement and electrical activity of the muscles of the limb at the chosen location; comparison means for comparing the monitoring parameter with the reference parameter; and output means for producing an output by comparison of the monitoring parameter and the reference parameter, the output comprising either recorded data which provide a record of an epileptic event in the prolonged period of time or an alarm output after the prolonged period of time when the monitoring parameter is outside a predetermined range compared to the reference parameter. | 03-10-2011 |
20120283801 | APPARATUS FOR DETECTING THE PRESENCE OF SKIN - The apparatus comprises | 11-08-2012 |
Harald R. Simonsen, Lejre DK
Patent application number | Description | Published |
---|---|---|
20100266251 | OPTICAL FIBER WITH IMPROVEMENTS RELATING TO LOSS AND ITS USE, METHOD OF ITS PRODUCTION AND USE THEREOF - The invention relates to an optical fiber having an axial direction and a cross section perpendicular to said axial direction, and a method and preform for producing such an optical fiber. The optical fiber is adapted to guide light at a wavelength λ, and comprises a core region, an inner cladding region surrounding said core region, and at least one of a first type of feature comprising a void and a surrounding first silica material. The core, the inner cladding region and the first type of feature extends along said axial direction over at least a part of the length of the optical fiber. The first silica material has a first chlorine concentration of about 300 ppm or less. | 10-21-2010 |
Henrik Simonsen, Aalborg DK
Patent application number | Description | Published |
---|---|---|
20140304201 | System And Method For Identifying Suggestions To Remedy Wind Turbine Faults - A method of automatically identifying suggestions regarding how to remedy wind turbine faults is provided, including establishing and storing a plurality of fault reports, each fault report including fault symptom information including data of identified fault symptoms of a previously occurred fault and fault remedy information, the fault remedy information including data regarding how the previously occurred fault was remedied, collecting fault related data, which includes data from one or more wind turbines exposed to an occurring fault, by a data processing arrangement performing data processing, including correlation of the fault related data with data from the stored fault reports, and based on the correlation establishing one or more fault remedy suggestions including suggestions regarding how to remedy the occurring fault related to the wind turbines based on the data processing. The invention also relates to a system for automatically identifying suggestions regarding how to remedy wind turbine faults. | 10-09-2014 |
Henry Fritz Simonsen, Trustrup DK
Patent application number | Description | Published |
---|---|---|
20110004151 | Treatment or Therapy Apparatus - The apparatus is arranged to supply a flow of substantially pure oxygen to a person, and comprises a source of substantially pure oxygen gas, means for release of the substantially pure oxygen gas from the source into an ambient atmosphere; and means for cooling the substantially pure oxygen gas released from the source to a temperature below that of the ambient atmosphere. The substantially pure oxygen gas when cooled by the cooling means can be allowed to sink under ambient pressure by convection into a zone including the ambient atmosphere, the zone being beneath, and in convective communication with, the cooled substantially pure oxygen gas, whereby the cooled and sunken substantially pure oxygen gas can come into contact with the skin of a person in that zone. At least one parameter (such as temperature, oxygen concentration, sound or vibration) is monitored in the zone and operation of the release means is only permitted when the parameter is in a predetermined range. | 01-06-2011 |
Jan Simonsen, Struer DK
Patent application number | Description | Published |
---|---|---|
20080290810 | DISCHARGE LAMP CONTROLS - At least one electric discharge lamp capable of generating a broadband output pulse of a range of wavelengths in the visible spectrum, the output pulse having a predetermined time interval and a predetermined total electrical energy input for the pulse, has a drive circuit for delivering energy pulses to the electrical discharge lamp, as well as a sensor for sensing an optical output from the discharge lamp; and a control mechanism for operating the drive circuit in response to variations in optical output detected by the sensor. | 11-27-2008 |
20110004151 | Treatment or Therapy Apparatus - The apparatus is arranged to supply a flow of substantially pure oxygen to a person, and comprises a source of substantially pure oxygen gas, means for release of the substantially pure oxygen gas from the source into an ambient atmosphere; and means for cooling the substantially pure oxygen gas released from the source to a temperature below that of the ambient atmosphere. The substantially pure oxygen gas when cooled by the cooling means can be allowed to sink under ambient pressure by convection into a zone including the ambient atmosphere, the zone being beneath, and in convective communication with, the cooled substantially pure oxygen gas, whereby the cooled and sunken substantially pure oxygen gas can come into contact with the skin of a person in that zone. At least one parameter (such as temperature, oxygen concentration, sound or vibration) is monitored in the zone and operation of the release means is only permitted when the parameter is in a predetermined range. | 01-06-2011 |
20110060252 | Monitoring Apparatus and Method - The apparatus for monitoring muscle contractions of a subject (for example as a check on epilepsy or Parkinson's disease) comprises: a first sensor arranged to be placed on a reference location on the body of a subject for sensing, over a prolonged period of time, a reference parameter derived from at least one of movement and electrical activity of the muscles of the body at the reference location; at least one further sensor arranged to be placed on a chosen location on a limb of a subject, for sensing, over a prolonged period of time, a monitoring parameter derived from at least one of movement and electrical activity of the muscles of the limb at the chosen location; comparison means for comparing the monitoring parameter with the reference parameter; and output means for producing an output by comparison of the monitoring parameter and the reference parameter, the output comprising either recorded data which provide a record of an epileptic event in the prolonged period of time or an alarm output after the prolonged period of time when the monitoring parameter is outside a predetermined range compared to the reference parameter. | 03-10-2011 |
20120283801 | APPARATUS FOR DETECTING THE PRESENCE OF SKIN - The apparatus comprises | 11-08-2012 |
Jan Simonsen, Naestved DK
Patent application number | Description | Published |
---|---|---|
20160032933 | ROTATING OIL UNION WITH CENTERLINE MOUNTED DISPLACEMENT PROBE, SYSTEM FOR MEASURING DISPLACEMENT OF REGULATION SYSTEM OF VARIABLE PITCH AXIAL FAN AND METHOD THEROF - A system is disclosed for measuring displacement of a regulation system for a variable pitch axial fan. The system includes a hub having a plurality of adjustable pitch fan blades. A hydraulic cylinder is connected to the hub. A piston is disposed within the hydraulic cylinder. The piston is coupled to a piston shaft that is axially movable with respect to the hub. The piston shaft is coupled to an actuation assembly for adjusting the pitch of the plurality of adjustable pitch fan blades in response to an axial movement of the piston. A rotating oil union includes a housing and an interior element, the interior element coupled to the hydraulic cylinder so that rotation of the cylinder and the hub causes rotation of the interior element. The rotating oil union includes a static housing and a central probe fixed to the static housing. The central probe extends through respective openings in the interior element, the hydraulic cylinder, and the piston. The central probe is configured to sense an axial position of the piston and to generate a signal representative of said axial position. A method for using the system is also disclosed. | 02-04-2016 |
Jens Simonsen, Nordborg DK
Patent application number | Description | Published |
---|---|---|
20090126509 | Mass Flow Meter - There is described a mass flow meter which operates on the Coriolis principle. A measuring tube is mounted in a chamber, which is provided with at least two openings for directing the medium to and from the respective end of the measuring tube. The mounting of the measuring tube is arranged between the two tube ends at an axial distance from them. It is preferably at an oscillation node of the first bending mode. The mounting arranged at an axial distance from the tube ends has the advantage that thermal expansions have virtually no influence on the internal mechanical stress conditions of the measuring tube, and consequently scarcely influence the measurement result. The mass flow meter can be used with particular advantage for gaseous media. | 05-21-2009 |
Jesper Schantz Simonsen, Copenhagen DK
Patent application number | Description | Published |
---|---|---|
20110230823 | VALVE MECHANISM FOR A SUCTION AND IRRIGATION INSTRUMENT - A valve mechanism for a suction or irrigation instrument, that includes a first tubular housing provided with at least one first distal conduit assembly for coupling to the instrument, and a conduit for communicating with a suction or irrigation source. The conduit assembly includes at least first and second proximal conduits, and a first piston movably arranged in the first tubular housing between first and second positions. The first piston has a first through-opening intersecting the longitudinal axis of the first piston, wherein upon movement of the first piston into the first position the first through-opening opens a pathway between the at least one first distal conduit and the first proximal conduit, and upon movement of the first piston into the second position the first through-opening opens a pathway through the at least one first distal conduit and the second proximal conduit. | 09-22-2011 |
20140358141 | ELECTROSURGICAL PENCIL WITH A SMOKE EVAPORATION TUBE - An electrosurgical pencil for cutting tissue during surgery by application of electrical energy supplied from a generator. A tube is provided for evacuation of smoke from the site of surgery. To improve flexibility and reduce the stiffness of the tube while maintaining generally the shape and ability of the tube to conduct smoke from the site, the tube comprises a polymer film, herein referred to as sheath stretched by at least one reinforcement element. | 12-04-2014 |
Jesper Schantz Simonsen, Koebenhavn DK
Patent application number | Description | Published |
---|---|---|
20140135757 | ELECTROSURGICAL INSTRUMENT AND ELECTROSURGICAL CONDUCTIVE ELECTRODE FOR USE WITH THE INSTRUMENT - An elongated electrosurgical instrument ( | 05-15-2014 |
20140142566 | COUPLING MEANS CONNECTING AN ELECTROSURGICAL INSTRUMENT TO A VACUUM SOURCE, AN ELECTROSURGICAL INSTRUMENT PROVIDED WITH THE COUPLING MEANS, A KIT INCLUDING THE COUPLING MEANS AND THEIR USES - A coupling means ( | 05-22-2014 |
20140142568 | ELONGATED ELECTROSURGICAL INSTRUMENT, A SUCTION TIP FOR THE ELECTROSURGICAL INSTRUMENT AND METHOD OF ADJUSTING THE AXIAL POSITION OF THE SUCTION TIP ON THE ELECTROSURGICAL INSTRUMENT - An elongated electrosurgical instrument ( | 05-22-2014 |
Jesper Schantz Simonsen, Kobenhavn DK
Patent application number | Description | Published |
---|---|---|
20140155890 | ELONGATED ELECTROSURGICAL INSTRUMENT, A SWITCH MEANS FOR SAID INSTRUMENT, AND AN ASSEMBLY KIT - An elongated electrosurgical instrument ( | 06-05-2014 |
20140371722 | METHODS OF MANUFACTURING FLEXIBLE POLYMERIC MEDICAL SPIRAL TUBINGS, TUBINGS MADE BY THE METHODS AND USES OF THE TUBINGS - Methods of manufacturing a length of a flexible polymeric medical tubing of the kind comprising a tubing member defining a lumen, which tubing member is surrounded by spiral convolutions along at least a part of the length of the proximal section and/or the distal section, and which medical tubing has a proximal convoluted section and a distal convoluted section, is disclosed, as well as medical tubings obtained by the methods and their uses. One method comprises the steps of providing a medical tubing wherein the proximal section and the distal section have substantially uniform initial pitch (P | 12-18-2014 |
Jesper Schantz Simonsen, Copenhagan DK
Patent application number | Description | Published |
---|---|---|
20100076381 | TROCAR VALVE SEALS - A valve seal for a trocar cannula having a distal end and an opposing proximal end with an enlarged section for accommodating at least a part of a valve seal. The valve seal has a tubular neck part defined by a first circumferential wall, an instrument leaving end and an opposing instrument receiving end, the instrument receiving end is provided with a first diaphragm valve and a circumferential flange connecting the tubular neck part with a substantially concentric second circumferential wall surrounding at least a part of the first circumferential wall to define a gap between said substantially concentric circumferential walls, at a distance from the first diaphragm valve the first circumferential wall of the tubular neck part is axially split up into an exterior tubular neck part and a substantially concentric interior tubular neck part provided with a second diaphragm valve, the interior tubular neck part terminating a distance from the instrument leaving end. The valve seal is moulded in its final form. The valve seal has at least three valves, which enhance sealing capability, and the design of the valve seal is suitable for trocars with cannulas of various diameters. | 03-25-2010 |
Kenneth Simonsen, Hadsten DK
Patent application number | Description | Published |
---|---|---|
20100283245 | WIND TURBINE - For optimising annual energy production in a wind turbine, the invention provides a method by which operation of the turbine in accordance with different pre-specified modes depending on the wind direction towards the turbine is enabled. The modes may include pitch and/or power control strategies. The invention further provides a control system for a wind turbine adapted to operate in accordance with the method, and a wind turbine with such a control system. | 11-11-2010 |
Kenneth Tougaard Simonsen, Hadsten DK
Patent application number | Description | Published |
---|---|---|
20150132128 | WIND TURBINE WITH A LOAD CONTROLLER - The invention provides a wind turbine, a control system for a wind turbine and a method for controlling a wind turbine where asymmetry in load on the rotor is compensated by individual pitching by comparing a load distribution over the rotor plane with a threshold value. To avoid unnecessary compensation, the threshold value is adjusted based on a loading of the wind turbine or based on climate conditions under which the turbine operates. | 05-14-2015 |
20150139797 | WIND TURBINE CONTROL - The present invention relates to methods, apparatus and computer program products for controlling a wind turbine that comprises a nacelle and one or more turbine blades to reduce or prevent edgewise vibrations building up on the one or more turbine blades. It is identified | 05-21-2015 |
Klaus B. Simonsen, Frederiksberg DK
Patent application number | Description | Published |
---|---|---|
20090143364 | CHIRAL CIS-IMIDAZOLINES - and the pharmaceutically acceptable salts and esters thereof, wherein X | 06-04-2009 |
Klaus Baek Simonsen, Odense DK
Patent application number | Description | Published |
---|---|---|
20100076016 | ISOQUINOLINONE DERIVATIVES AS NK3 ANTAGONISTS - The invention relates to compounds useful in therapy, in particular in the treatment of psychosis, to compositions comprising said compounds, and to methods of treating diseases comprising the administration of said compounds. | 03-25-2010 |
20110130407 | ISOQUINOLINONE DERIVATIVES AS NK3 ANTAGONISTS - Isoquinolone derivatives of the general formula I are provided. The compounds are NK3 antagonists and useful for the treatment of e.g. psychosis and schizophrenia. | 06-02-2011 |
20150274736 | PDE9i with imidazo pyrazinone backbone - This invention is directed to compounds, which are PDE9 enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula (I). The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula (I). The present invention further provides a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula (I). | 10-01-2015 |
Klaus Baek Simonsen, Odense M DK
Patent application number | Description | Published |
---|---|---|
20090143402 | ISOQUINOLINONE DERIVATIVES AS NK3 ANTAGONISTS - Isoquinolone derivatives of the general formula | 06-04-2009 |
20110130420 | ISOQUINOLINONE DERIVATIVES AS NK3 ANTAGONISTS - Isoquinolone derivatives of the general formula Ik″ are provided. The compounds are NK3 antagonists and useful for the treatment of e.g. psychosis and schizophrenia. | 06-02-2011 |
20110224247 | AZAISOQUINOLINONE DERIVATIVES AS NK3 ANTAGONISTS - The invention relates to compounds useful in therapy, in particular in the treatment of psychosis, to compositions comprising said compounds, and to methods of treating diseases comprising the administration of said compounds. | 09-15-2011 |
20110288120 | ISOQUINOLINONE DERIVATIVES AS NK3 ANTAGONISTS - Isoquinolone derivatives of the general formula (I) are NK3 antagonists. | 11-24-2011 |
20130190499 | Azaisoquinolinone derivatives as NK3 antagonists - The invention relates to compounds useful in therapy, in particular in the treatment of psychosis, to compositions comprising said compounds, and to methods of treating diseases comprising the administration of said compounds. | 07-25-2013 |
20150045348 | PDE9 inhibitors with imidazo triazinone backbone - This invention is directed to compounds, which are PDE9 enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula (I). The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula (I). The present invention further provides a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula (I). | 02-12-2015 |
Knud Simonsen, Slagelse DK
Patent application number | Description | Published |
---|---|---|
20090323465 | MIXER - The present invention is related to an apparatus for massaging and/or tumbling of a product with a drum and a shaft with paddles rotated by a motor. | 12-31-2009 |
Peter Soren Siersbaek Simonsen, Sonderborg DK
Patent application number | Description | Published |
---|---|---|
20120089289 | INTUITIVE FORCE CONTROLLED SYSTEM - The invention relates to a transportation unit ( | 04-12-2012 |