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Silke
Silke Appel-Dingemanse, Allschwil CH
| Patent application number | Description | Published |
|---|---|---|
| 20090275553 | DOSAGE REGIMEN OF AN S1P RECEPTOR AGONIST - S1P receptor modulators or agonists are administered following a dosage regimen whereby during the initial 3 to 6 days of treatment the daily dosage is raised so that in total the R-fold (R being the accumulation factor) standard daily dosage is administered and thereafter continued at the standard daily dosage or at a daily dosage lower than the standard daily dosage. | 11-05-2009 |
Silke Arians, Hamburg DE
| Patent application number | Description | Published |
|---|---|---|
| 20080288918 | WEB SERVICE TOOL BASED ON BUSINESS OBJECT LAYER - A system for generating a Web service includes a graphical user interface to guide a designer to create a Web service in pre-defined stages. The graphical user interface receives an input that selects an object and associated attributes from a repository of pre-defined business objects. The system includes a Web service generator that automatically generates code describing and implementing the Web service according to the selected object and attributes. The system also includes a Web service engine to perform runtime operations of the Web service. | 11-20-2008 |
Silke Baasner, Schoneck DE
| Patent application number | Description | Published |
|---|---|---|
| 20080280965 | Novel tetrahydrocarbazole derivatives having improved biological action and improved solubility as ligands of G-protein coupled receptors (GPCPs) - The present invention provides novel tetrahydrocarbazole derivatives which have improved properties and which can be employed as inhibitors of GPCRs. This results in the possibility of using the novel compounds to treat pathological conditions whose severity depends on the pathobiochemical effect of GPCRs. The compounds of the invention act in particular via an antagonistic inhibition of the LHRH receptor. The invention further provides medicaments which comprise one or more of the novel compounds as active ingredient. The medicaments are suitable in particular to be employed in an oral dosage form for a mammal, in particular a human. | 11-13-2008 |
| 20090311264 | Use of Disorazoles and Their Derivatives for the Treatment of Benign and Malignant Oncoses - The invention relates to disorazoles of the general formula I, which are employed as medicaments, preferably for the treatment of oncoses, in particular in the case of pharmaceutical resistance to other active compounds and in the case of metastasizing carcinoma. The possible uses are not restricted to oncoses. | 12-17-2009 |
Silke Baasner, Schoeneck DE
| Patent application number | Description | Published |
|---|---|---|
| 20090170783 | NOVEL TETRAHYDROCARBAZOLE DERIVATIVES AS LIGANDS OF G-PROTEIN COUPLED RECEPTORS - The present invention provides novel tetrahydrocarbazole compounds according to formula (I) as ligands of G-protein coupled receptors (GPCR) which are useful in the treatment and/or prophylaxis of physiological and/or pathological conditions in mammals mediated by GPCR or of physiological and/or pathological conditions which can be treated by modulation of these receptors. | 07-02-2009 |
Silke Biedasek, Mannheim DE
| Patent application number | Description | Published |
|---|---|---|
| 20090131549 | PROCESS FOR PREPARING POLYVINYLPYRROLIDONES BY SPRAY POLYMERIZATION - A process for preparing polyvinylpyrrolidones by free-radically initiated polymerization in the presence of an initiator found, which comprises performing the polymerization as a spray or droplet polymerization. | 05-21-2009 |
Silke Buhler-Paschen, Vienna AT
| Patent application number | Description | Published |
|---|---|---|
| 20090291297 | Method for producing clathrate compounds - The present invention relates a method for producing clathrate compounds, comprising producing a homogeneous melt containing the desired elements in the desired ratio, and subsequently solidifying said melt to obtain the clathrate compound by quickly cooling the melt. | 11-26-2009 |
Silke Courtenay, San Diego, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100297419 | DUAL TREATED SILICA, METHODS OF MAKING DUAL TREATED SILICA, AND INKJET RECORDING MATERIALS - Briefly described, embodiments of this disclosure include methods of preparing dual treated silica, methods of preparing a photobase porous medium, photobase porous media, are disclosed. | 11-25-2010 |
Silke Denzin, Langenfeld DE
| Patent application number | Description | Published |
|---|---|---|
| 20090192064 | MULTIPLE ENZYME CLEANER FOR SURGICAL INSTRUMENTS AND ENDOSCOPES - The liquid composition is based on surfactants and enzymes, and is particularly useful for manual cleaning of instruments. In manual and ultrasonic application the composition in use concentration shows low foaming and gives a cleaning solution which is not cloudy at least at a temperature in the range from 16° C. to 40° C. In addition, the composition has good cleaning efficacy over a broad temperature range (20 to 55° C.) and shows good material compatibility. | 07-30-2009 |
| 20100095988 | MULTIPLE ENZYME CLEANER FOR SURGICAL INSTRUMENTS AND ENDOSCOPES - The liquid composition is based on surfactants and enzymes, and is particularly useful for manual cleaning of instruments. In manual and ultrasonic application the composition in use concentration shows low foaming and gives a cleaning solution which is not cloudy at least at a temperature in the range from 16° C. to 40° C. In addition, the composition has good cleaning efficacy over a broad temperature range (20 to 55° C.) and shows good material compatibility. | 04-22-2010 |
| 20100297029 | VIRUCIDAL COMPOSITION - The invention relates to a virucidal composition comprising based on the composition | 11-25-2010 |
| 20110061686 | MULTIPLE ENZYME CLEANER FOR SURGICAL INSTRUMENTS AND ENDOSCOPES - The liquid composition is based on surfactants and enzymes, and is particularly useful for manual cleaning of instruments. In manual and ultrasonic application the composition in use concentration shows low foaming and gives a cleaning solution which is not cloudy at least at a temperature in the range from 16° C. to 40° C. In addition, the composition has good cleaning efficacy over a broad temperature range (20 to 55° C.) and shows good material compatibility. | 03-17-2011 |
Silke De-Zolt, Rodenbach DE
| Patent application number | Description | Published |
|---|---|---|
| 20090113561 | GENE TRAP CASSETTES FOR RANDOM AND TARGETED CONDITIONAL GENE INACTIVATION - A new type of gene trap cassette, which can induce conditional mutations, relies on directional site-specific recombination systems, which can repair and re-induce gene trap mutations when activated in succession. After the gene trap cassettes are inserted into the genome of the target organism, mutations can be activated at a particular time and place in somatic cells. The gene trap cassettes also create multipurpose alleles amendable to a wide range of post-insertional modifications. Such gene trap cassettes can be used to mutationally inactivate all cellular genes temporally and/or spatially. Cells which contain the inventive gene trap cassette can be used for identification and/or isolation of genes and for the creation of transgenic organisms to study gene function at various developmental stages, including the adult, as well as for the creation of animal models of human disease useful for in vivo drug target validation. | 04-30-2009 |
| 20100132055 | ANIMAL MODEL FOR THE SELECTION AND VALIDATION OF AGENTS ACTIVE AGAINST PULMONARY EMPHYSEMA AND COLORECTAL CANCER - The present invention relates to a non-human animal model, cell and tissue cultures derived therefrom, which do not produce or produce only suboptimal levels of one or more functional sestrins and in addition do not produce or do only produce suboptimal levels of latent transforming growth factor β binding protein 4 (ltbp4). Furthermore, the present invention relates to a method for selecting agents for treating the pulmonary emphysema and/or the colorectal cancer exhibited by utilizing the animal model, cell or tissue culture of the invention. The animal model, cell or tissue culture is suitable for preclinical testing of efficacy, toxicity and bioavailability of potential agents. | 05-27-2010 |
Silke Dlugai, Munchen DE
| Patent application number | Description | Published |
|---|---|---|
| 20100203617 | USE OF SACCHAROMYCES CEREVISIAE ERG4 MUTANTS FOR EXPRESSING MAMMALIAN GLUCOSE TRANSPORTERS - The invention relates to yeast strains in which a human GLUT4 transport or a human GLUT1 transporter can be functionally expressed and to particular GLUT4 transport proteins which can be functionally expressed particularly readily in yeast strains. | 08-12-2010 |
Silke Ebbing, Karlsruhe DE
| Patent application number | Description | Published |
|---|---|---|
| 20110076714 | Method for the presence detection of microorganisms in a bioreactor, bioreactor and arrangement - The invention relates to a method for the presence detection of microorganisms in a bioreactor (B), to a bioreactor (B), and to an arrangement for performing the detection method. In order to reduce the staffing expense during the detection analysis of the presence of undesirable microorganisms in a bioreactor (B) after the bioreactor (B) has been cleaned, the detection method is carried out for microorganisms present in a bioreactor (B) such that a) a nutrient medium is selectively applied to defined areas of the bioreactor (B) in a controlled manner by a control unit (SE), b) an incubation having a defined time is performed in the bioreactor (B), c) after the incubation has been completed, the nutrient medium is removed from the defined areas in the bioreactor (B) and fed to an analysis unit (AE), in which the presence of microorganisms or decomposition products is determined, d) the analysis result determined in c) is then sent to the control unit (SE), which based on the results of the analysis selects a suitable process step from the predefined process steps for the further operation of the bioreactor (B). | 03-31-2011 |
Silke Erbeck, Kolliken CH
| Patent application number | Description | Published |
|---|---|---|
| 20090247755 | Process for Preparing a Substituted Imidazopyridine Compound - The present invention provides a new process for large-scale preparation of substituted imidazopyridine compound of formula (I) wherein R | 10-01-2009 |
Silke Goronzy, Erlangen DE
| Patent application number | Description | Published |
|---|---|---|
| 20090282034 | METHODS TO CREATE A USER PROFILE AND TO SPECIFY A SUGGESTION FOR A NEXT SELECTION OF A USER - A user profile and/or the suggestions computed based thereon are obtained taking a special set of user features into account. The user features are defined to represent a typical general behaviour of an individual user in respect to the application where the user profile is used. In other words, for each application where a user profile is used a special set of user features are defined which are able to represent a typical general behaviour of an individual user. Based on these user features the weights in the list of word-weight pairs or weighted keywords which represents the user profile are computed or influenced during the creation of the user profile, and/or a mufti-user profile is split during the creation of an individual user profile from a mufti-user profile, and/or during specification of a suggestion a user history which is used to create the user profile, and/or the user profile, and/or the suggestion results are filtered. | 11-12-2009 |
Silke Guga, Lubeck DE
| Patent application number | Description | Published |
|---|---|---|
| 20110236987 | GAS DETECTOR TUBE FOR DETERMINING BENZENE - An improved detection reaction for benzene in gas analysis with a gas detector tube formed of a carrier material impregnated with gold(III) oxide in a display layer. | 09-29-2011 |
Silke Gürtler, Uttenreuth DE
| Patent application number | Description | Published |
|---|---|---|
| 20110135132 | HEARING DEVICE WITH MECHANICAL ADJUSTMENT OF SOUND PROPERTIES - A hearing device that is worn in the ear has a hearing aid and a support device with a runner. The support device remains stationarily inserted in the auditory canal, while the hearing aid is moveably connected to the runner and moveably arranged along the runner. This provides for a hearing device that allows a simple, intuitively understandable modification of the volume and/or sound properties. | 06-09-2011 |
Silke Hinnah, Hamburg DE
| Patent application number | Description | Published |
|---|---|---|
| 20110105348 | Method for detecting an analyte in a sample - The present invention relates to a method for detecting an analyte in a sample comprising the steps of | 05-05-2011 |
Silke Hofmann, Wallenfels DE
| Patent application number | Description | Published |
|---|---|---|
| 20100028903 | METHOD AND DEVICE FOR EXAMINING THE ATTACHMENT OR DETACHMENT OF LIVING OR DEAD CELLS OR CELL-LIKE PARTICLES OR OTHER SURFACE ACCUMULATIONS ON SURFACES BY MEANS OF PLASMON RESONANCE AND USE OF SAID METHOD AND SAID DEVICE - The invention relates to the examination of the attachment or detachment of living or dead cells, or cell-like particles, or other surface accumulations on surfaces, by means of plasmon resonance. The reflected light is evaluated such that two or more intensity minima of the reflected light occurring within a time frame are registered in a time dependant manner for different incident angles. The registered measurement signals reflect the respective amount of the surface accumulation. In case two intensity minima have occurred at the same time, valuable information about particular processes regarding the surface accumulation, for example regarding the adhesion of cells, can be obtained. Said information is of particular importance in the field of medicine/biology. | 02-04-2010 |
Silke Holtmanns, Vantaa FI
| Patent application number | Description | Published |
|---|---|---|
| 20120011574 | GENERIC KEY-DECISION MECHANISM FOR GAA - A method and apparatus provide generic mechanism for a network application server. A receiver receives a request from a user equipment to provide authentication information to a network application function. A determining unit determines a key of a generic authentication architecture to integrate additional network application servers by extending an existing standard for user security settings. A providing unit provides the authentication information to the network application function. | 01-12-2012 |
Silke Holtmanns, Klaukkala FI
| Patent application number | Description | Published |
|---|---|---|
| 20080215758 | Method For Software Program Synchronization - A method, devices, and a computer program for synchronizing one or more software programs from a first device (D | 09-04-2008 |
| 20080294560 | Method of storing content - A method comprising receiving at a user equipment encrypted content. The content is stored in said user equipment in an encrypted form. At least one key for decryption of said stored encrypted content is stored in the user equipment. | 11-27-2008 |
| 20080307518 | Security in communication networks - Disclosed is a method including allowing an application server to request setup of a session on behalf of a user terminal, and using mechanisms of a generic peer authentication procedure for procedure for enabling authentication of the application server to an interrogating server, the interrogating server being a network element that is configured to process said request to setup a session on behalf of a user terminal. Also disclosed are related devices, systems and computer programs. | 12-11-2008 |
| 20090191857 | Universal subscriber identity module provisioning for machine-to-machine communications - The present invention relates to remotely provisioning subscriber identification parameters in a device on a wireless network. A secure connection is established with the device, and a token containing the new subscriber identification parameters is forwarded over the secure connection. The device may verify the received token. In one embodiment, the subscriber identification parameters are updated to change network operators. The secure connection can be with the old network operator or the new network operator. The device on the wireless network may be a machine-to-machine device. The provisioned subscriber identification may be part of a universal subscriber identification module. | 07-30-2009 |
| 20090232310 | Method, Apparatus and Computer Program Product for Providing Key Management for a Mobile Authentication Architecture - An apparatus for providing key management for a mobile authentication architecture may include a processor. The processor may be configured to provide a request for key revocation over an interface otherwise defined for sharing key acquisition information between a bootstrapping server function and a network application function, and cancel key information associated with the request for key revocation. | 09-17-2009 |
| 20100303242 | METHODS, APPARATUSES, SYSTEM AND COMPUTER PROGRAMS FOR KEY UPDATE - It is disclosed a method comprising monitoring validity of limited-validity key information, acquiring, from a net-work entity upon invalidity of the limited-validity key information, limited-validity transaction identification information based on unlimited-validity identification information identifying a terminal, generating new limited-validity key information based on the acquired limited-validity transaction identification information, and transmitting the acquired limited-validity transaction identification information to a network element. | 12-02-2010 |
| 20110173105 | Utilizing AAA/HLR infrastructure for Web-SSO service charging - An apparatus (such as a AAA node of a core/operator network) receives from a relying party an initial credit control request that bears first information comprising a relying party identifier, a service context identifier for a service to be provided by the relying party, and a token that authenticates a subscriber. The first information is extracted and forwarded to a core network accounting server that stores account information for the subscriber. The relying party is not within the core network. In reply to forwarding the extracted first information, the apparatus receives from the accounting server a credit control answer that bears second information comprising the relying party identifier, the service context identifier, and a grant indicating the subscriber may be charged a fee for the service to be provided by the relying party. The second information is extracted and forwarded to the relying party. | 07-14-2011 |
| 20110213959 | METHODS, APPARATUSES, SYSTEM AND RELATED COMPUTER PROGRAM PRODUCT FOR PRIVACY-ENHANCED IDENTITY MANAGEMENT - A method and related apparatus include the steps of registering, from a client at a service providing network entity, first client-related identity information and, from the client at an identity providing network entity, second client-related identity information being different from the first client-related identity information and being generated based on the first client-related identity information. Key information is a secret of the client and identity information is related to the service providing network entity. A second method and related apparatus include the step of determining, at a service providing network entity, the first client-related identity information based on the second client-related identity information being received from the identity providing entity. Finally, a third method and related apparatus include the step of authenticating, towards the service providing network entity, the second client-related identity information being received from the client. | 09-01-2011 |
| 20110289315 | Generic Bootstrapping Architecture Usage With WEB Applications And WEB Pages - A method includes receiving at a network application function a request related to a generic bootstrapping architecture key originated from a user equipment. The received request includes a network application function identifier that includes a uniform resource locator, where the network application function has a fully qualified domain name. The method further includes causing a generic bootstrapping architecture key to be generated for the user equipment based at least in part on the uniform resource locator that is part of the network application function identifier. Apparatus and computer programs for performing the method are also disclosed. | 11-24-2011 |
Silke Holtmanns, Klaukkla FI
| Patent application number | Description | Published |
|---|---|---|
| 20110145583 | Smart Card Security Feature Profile in Home Subscriber Server - In accordance with the exemplary embodiments of the invention there is at least a method, an executable computer program, and an apparatus to determine at a network application function a list of desired user equipment security features to be used, the security features of the list ordered by preference of the network application function, send the list to a database of user security settings via a bootstrapping server function, and receive by the network application function, via the bootstrapping server function, a security features response including a security key, derived from information stored in the database, corresponding to a desired security feature contained in the list, thereby informing the network application function of the availability of at least one of the desired security features in the user equipment. | 06-16-2011 |
Silke Hottenbacher, Münster GB
| Patent application number | Description | Published |
|---|---|---|
| 20110245406 | COATING COMPOSITIONS AND COATINGS PRODUCED FROM THEM WITH HIGH SCRATCH RESISTANCE, WEATHERING STABILITY, AND GOOD OPTICAL PROPERTIES - The invention relates to coating compositions comprising | 10-06-2011 |
Silke Hottenbacher, Munster DE
| Patent application number | Description | Published |
|---|---|---|
| 20110263789 | CLEAR PAINT COMPOSITIONS COMPRISING HYPERBRANCHED, DENDRITIC, HYDROXYL- FUNCTIONAL POLYESTERS - Disclosed is a hyperbranched, dendritic, hydroxyl-functional polyester comprising an OH number greater than or equal to 180 mg KOH/g as measured via DIN 53240 and to clearcoat compositions comprising said polyesters. Also disclosed are processes for preparing the disclosed polyester, methods of making coated automotive substrates by applying the disclosed clearcoat compositions to automotive substrates, and to coated substrates made therefrom. | 10-27-2011 |
Silke Hüttler, Altenmoor DE
| Patent application number | Description | Published |
|---|---|---|
| 20110293590 | PHARMACEUTICAL PREPARATION - The pharmaceutical preparation for the treatment of pancreatic insufficiency comprises a liquid administering form of enzymes. | 12-01-2011 |
Silke Jerrentrup, Bielefeld DE
| Patent application number | Description | Published |
|---|---|---|
| 20080261269 | ALLELES OF THE OXYR GENE FROM CORYNEFORM BACTERIA - The invention relates to mutants and alleles of the oxyR gene of coryneform bacteria coding for variants of the OxyR transcription regulator and processes for producing amino acids using bacteria which comprise these alleles. | 10-23-2008 |
Silke Knoche, Budenheim DE
| Patent application number | Description | Published |
|---|---|---|
| 20090233082 | Glass or glass-ceramic articles with decorative coating - In order to provide a decorative coating ( | 09-17-2009 |
Silke Koslowsky, Potsdam DE
| Patent application number | Description | Published |
|---|---|---|
| 20100037350 | PLANTS WITH INCREASED YIELD - This invention relates generally to plant cells and/or plants with increased yield as compared to a corresponding non-transformed wild type plant cell by increasing or generating one or more activities of polypeptides associated with the intermediate phosphoribosylpyrophosphate (PRPP) in plants. In particular, this invention relates to plant cells and/or plants with increased yield as compared to a corresponding non-transformed wild type plant cell by increasing or generating one or more activities of phosphoribosyl pyrophosphate synthases (PRPP synthetase, PRS) The invention also deals with methods of producing and screening for and breeding such plant cells and/or plants. | 02-11-2010 |
Silke Krol, Basovizza(trieste) IT
| Patent application number | Description | Published |
|---|---|---|
| 20110111040 | POLYELECTROLYTE-ENCAPSULATED GOLD NANOPARTICLES CAPABLE OF CROSSING BLOOD-BRAIN BARRIER - A gold-creatine nanoparticle is described, preferably covered with albumin, together with a process for its preparation and its use as medicament, in particular for the treatment of stroke. Said gold nanoparticle is capable of crossing the blood-brain barrier. | 05-12-2011 |
Silke Krol, Trieste IT
| Patent application number | Description | Published |
|---|---|---|
| 20110262546 | GOLD NANOPARTICLES COATED WITH POLYELECTROLYTES AND ALBUMIN - It is described a gold nanoparticle coated with from two to five layers of a combination of a polyelectrolyte having amino functionality and a polyelectrolyte having sulfonic functionality, or with one single layer of said polyelectrolyte having amino functionality, preferably polyallylamine, or sulfonic functionality, preferably polystyrenesulfonic, characterized in that said nanoparticle comprises an outer layer of albumin. It is also described the process for its preparation, its use as carriers intended to cross blood-brain barrier and its use as medicament, in particular for treatment of neurodegenerative diseases, more in particular of diseases caused by protein aggregates, such as prion diseases, Alzheimer's disease, Parkinson's disease, Huntington's disease and amyotrophic lateral sclerosis. Also described are pharmaceutical compositions comprising said nanoparticle. | 10-27-2011 |
Silke Kühnrich, Volklingen DE
| Patent application number | Description | Published |
|---|---|---|
| 20110168619 | FILTER DEVICE AND FILTER ELEMENT - The invention relates to a filter device having a cup-shaped filter housing ( | 07-14-2011 |
Silke Kustermann, Buchs Sg CH
Silke Langwaldt, Rosengarten DE
| Patent application number | Description | Published |
|---|---|---|
| 20100143618 | COMPOSITE COMPONENT AND A METHOD AND DEVICE FOR PRODUCING THE COMPOSITE COMPONENT - In a method and apparatus for producing a composite component comprising a hollow profile and at least one injection-molded element, a hollow profile ( | 06-10-2010 |
Silke Lankiewicz, Langenhagen DE
| Patent application number | Description | Published |
|---|---|---|
| 20080305480 | NOVEL TUMOR MARKER - The present invention concerns a gene product largely homologous to the epithelial growth factor receptor (EGFR). It further refers to mRNA coding for such epithelial growth factor receptor. The present invention provides such an epithelial growth factor receptor which is characterized in that either exons 12 to 14 or exons 12 to 15 are deleted. These novel variants of the epithelial growth factor receptor can be used for a diagnosis, stratification, therapy guidance of a tumor or therapy guidance of tumor surgery. | 12-11-2008 |
| 20100216148 | NOVEL TUMOR MARKER - The present invention concerns a gene product largely homologous to the epithelial growth factor receptor (EGFR). It further refers to mRNA coding for such epithelial growth factor receptor. The present invention provides such an epithelial growth factor receptor which is characterized in that either exons 12 to 14 or exons 12 to 15 are deleted. These novel variants of the epithelial growth factor receptor can be used for a diagnosis, stratification, therapy guidance of a tumor or therapy guidance of tumor surgery. | 08-26-2010 |
Silke Miller, Newbury Park, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090264465 | CRYSTALLINE FORMS OF 4- [2- (4-METHYLPHENYLSULFANYL) -PHENYL] PIPERIDINE WITH COMBINED SEROTONIN AND NOREPINEPHRINE REUPTAKE INHIBITION FOR THE TREATMENT OF NEUROPATHIC PAIN - Crystalline forms of 4-[2-(4-methylphenylsulfanyl)-phenyl]piperidine and salts thereof are provided e.g. for the treatment of neuropathic pain. | 10-22-2009 |
| 20100137366 | 4- [2- (4-METHYLPHENYLSULFANYL) PHENYL] PIPERIDINE FOR THE TREATMENT OF IRRITABLE BOWEL SYNDROME (IBS) - The use of 4-[2-(4-methylphenylsulfanyl)phenyl]piperidine or a pharmaceutically acceptable salt thereof in the treatment of irritable bowl syndrome. | 06-03-2010 |
| 20100144788 | 4- [2- (4-METHYLPHENYLSULFANYD-PHENYL] PIPERIDINE WITH COMBINED SEROTONIN AND NOREPINEPHRINE REUPTAKE INHIBITION FOR THE TREATMENT OF ADHD, MELANCHOLIA, TREATMENT RESISTENT DEPRESSION OR RESIDUAL SYMPTOMS IN DEPRESSION - The use of 4-[2-(4-methylphenylsulfanyl)phenyl]piperidine and acid additions salts thereof for the treatment of ADHD, melancholia, treatment resistant depression or residual symptoms in depression is provided. | 06-10-2010 |
| 20110053978 | THERAPEUTIC USES OF COMPOUNDS HAVING AFFINITY TO THE SEROTONIN TRANSPORTER, SEROTONIN RECEPTORS AND NORADRENALIN TRANSPORTER - Therapeutic uses of 4-[2-(4-methylphenylsulfanyl)phenyl]piperidine and therapeutically acceptable salts thereof are provided. | 03-03-2011 |
Silke Mittelstrass, Munchen DE
| Patent application number | Description | Published |
|---|---|---|
| 20090053223 | EXPRESSION-ENHANCED POLYPEPTIDES - A composite polypeptide, said composite polypeptide comprising a desired polypeptide and an expression enhancing domain (“EED”), said EED comprising first and second cysteine amino acid residues Cys1 and Cys2, respectively, Cys1 being located closer to the N-terminus of the composite polypeptide molecule than Cys2, wherein Cys1 and Cys2 are separated by a polypeptide linker, said linker—being free of cysteine and proline;—defining a length sufficient to allow Cys1 and Cys2 to engage in an intramolecular disulfide bond with one another; and—having a flexible polypeptide conformation essentially free of secondary polypeptide structure in aqueous solution, wherein at least one of Cys1 and Cys2 is derivatized with a derivatization moiety. | 02-26-2009 |
Silke Muckenfuss, Langenfeld DE
| Patent application number | Description | Published |
|---|---|---|
| 20110192321 | Storage-stable Silicate Solutions - Disclosed are aqueous solutions of silicates (waterglasses), comprising (a) 20 to 40% by weight of SiO | 08-11-2011 |
Silke Nicklisch, Leipzig DE
| Patent application number | Description | Published |
|---|---|---|
| 20100022781 | TRYPSIN-LIKE SERINE PROTEASE INHIBITORS, AND THEIR PREPARATION AND USE - The invention relates to inhibitors of trypsin-like serine proteases of the general formula (I) which, as well as plasmin, also inhibit plasma kallikrien, and to their preparation and use as medicaments, preferably for treatment of blood loss, especially in the case of hyperfibrinolytic states, in organ transplants or heart surgery interventions, in particular with a cardiopulmonary bypass, or as a constituent of a fibrin adhesive. | 01-28-2010 |
Silke Petsch (nee Mittelstrass), Munich DE
| Patent application number | Description | Published |
|---|---|---|
| 20090297532 | Antibody Neutralizers of Human Granulocyte Macrophage Colony Stimulating Factor - The present invention relates to a human monoclonal antibody or fragment thereof which specifically binds to and neutralizes primate GM-CSF. | 12-03-2009 |
Silke Petsch (nee Mittelstrass), Penzberg DE
| Patent application number | Description | Published |
|---|---|---|
| 20120009195 | ANTIBODY NEUTRALIZERS OF HUMAN GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR - The present invention relates to a human monoclonal antibody or fragment thereof which specifically binds to and neutralizes primate GM-CSF. | 01-12-2012 |
Silke Pschibl, Rangendingen DE
| Patent application number | Description | Published |
|---|---|---|
| 20080312589 | Method of Producing a Ballon Catheter - A method of producing a balloon of a balloon catheter includes the following method steps: providing a balloon body coupled to a proximal sleeve and a distal sleeve by transitional sections extending between the balloon body and the sleeves; creating folds in at least the distal sleeve; and stabilizing at least a distal section of the folds of the distal sleeve. | 12-18-2008 |
| 20110029060 | LAMELLAR SHAPED LAYERS IN MEDICAL DEVICES - The present invention refers to medical devices. Particularly it relates to stent devices and balloon catheter devices. In the most particular aspect of the invention it relates to structures with at least two different lamellar sections used in such a medical device, especially in a balloon on a balloon catheter device carrying a stent comprising at least one layer with at least two lamellar sections different by their shore hardness and its use in a variety of medical procedures to treat medical conditions in animal and human patients. | 02-03-2011 |
| 20110284498 | METHOD OF REDUCING RIGIDITY OF ANGIOPLASTY BALLOON SECTIONS - A dilatation balloon is fabricated according to a process that forms cavities and indentations in the balloon and/or catheter sections. A length of tubing is axially elongated and radially expanded in a form to provide the requisite biaxial orientation and strength. Then, an excimer laser or another type of laser or mechanical material removal tool is used to remove the polymeric material, virtually without thermal effects. Cavities in the sleeve sections of the balloon are defined and if desired, indentations in the cone sections are defined. Material removal, particularly near the balloon sleeves enables a thinner, more flexible bonding area between the catheter shaft and the balloon. Further, the indentations along the cone sections enables tighter wrapping of the balloon for a reduced delivery profile. Rigidity near the sleeves is reduced for better maneuverability of the catheter in tortuous passageways. | 11-24-2011 |
Silke Richter, Wiesbaden DE
| Patent application number | Description | Published |
|---|---|---|
| 20100068493 | Hazy polyester film with improved technology - A hazy polyester film with a thickness in the range from 10 to 100 μm including thermoplastic polyester as the main constituent and barium sulfate with a particle size in the range from 0.1 to 0.5 μm, expressed as d | 03-18-2010 |
Silke Seuling, Kornwestheim DE
| Patent application number | Description | Published |
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| 20100116252 | Method and control unit for operating an injection valve - In a method for operating an injection valve, in particular a fuel injector of an internal combustion engine of a motor vehicle, one component of the injection valve, particularly a valve needle, is disposed in a manner allowing movement relative to other components of the injection valve, and preferably is able to be driven at least partially by an actuator. A structure-borne-noise signal is detected by a structure-borne-noise sensor, and the structure-borne-noise signal is evaluated in order to infer an operating state of the movably disposed component. | 05-13-2010 |
| 20100121555 | METHOD AND DEVICE FOR OPERATING A COMBUSTION ENGINE - A method for setting a combustion in a combustion engine, particularly in a diesel engine, having the following steps of generating a manipulated variable, particularly a point of injection (PI), as a function of a combustion feature (MFB50%), the combustion feature (MFB50%) representing a condition in cylinder, especially a pressure characteristic in the cylinder, and setting the combustion in cylinders of the combustion engine with the aid of the manipulated variable, the manipulated variable further being generated as a function of a correction value (CV), which is determined as a function of combustion information (dQ | 05-13-2010 |
Silke Simon, Wilmslow GB
| Patent application number | Description | Published |
|---|---|---|
| 20090187030 | PROCESS FOR CONTINUOUSLY PREPARING N-ETHYL-2-PYRROLIDONE (NEP) - Process for the continuous preparation of N-ethyl-2-pyrrolidone (NEP) by reacting gamma-butyrolactone (GBL) with monoethylamine (MEA) in the liquid phase, wherein GBL and MEA are used in a molar ratio in the range from 1:1.08 to 1:2 an the reaction is carried out at a temperature in the range from 320 to 420° C. and an absolute pressure in the range from 70 to 120 bar. | 07-23-2009 |
Silke Stusgen, Dusseldorf DE
| Patent application number | Description | Published |
|---|---|---|
| 20090092831 | Carbon Fiber - Carbon fibers and carbon fiber yarn consisting of carbon fibers, the fibers having been pretreated by electrochemical oxidation, characterized in that they have a finish consisting of epoxy resin(s), a vinyl component, and a plasticizer in an amount of 0.3 to 5 wt. % relative to the carbon fibers, which are to be provided with the finish. | 04-09-2009 |
Silke Teike, Elsdorf DE
| Patent application number | Description | Published |
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| 20090250400 | ABSORBENTS, PROCESS FOR THE PRODUCTION THEREOF AND USE THEREOF - An adsorbent for organic compounds consisting of filler granules, which contain 20 to 99.9 wt. % of fillers and a binder. The adsorbent is produced by mixing at least one binder with at least one filler and performing granulation in a mixing or granulation apparatus. The adsorbent may be used for adsorbing and/or absorbing organic and/or inorganic substances from a liquid or gaseous phase. | 10-08-2009 |
Silke Thomsen-Bosslet, Berlin DE
| Patent application number | Description | Published |
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| 20110008249 | PROTEINS WITH HIGH IMMUNOREACTIVITY AND METHOD FOR THEIR PRODUCTION - The invention relates to (glyco-) proteins, in particular monoclonal antibodies, which have an immunoreactivity of >81%, preferably >90%. The inventive monoclonal antibodies are produced using a fluidized bed reactor in conjunction with a conventional protein-chemical purification method or preferably with a purification method involving less column chromatography. The monoclonal antibodies thus produced are suitable, in gamma-irradiated form, e.g. Tc-99m labeled, for the in vivo diagnosis of inflammatory diseases and bone marrow metastases. In alpha- or beta-irradiated form, e.g. astatine or Re-188 or Y-90 labeled form, the inventive monoclonal antibodies can be used, for example, in the treatment of leukemia. | 01-13-2011 |
Silke Wodberg, Gevelsberg DE
| Patent application number | Description | Published |
|---|---|---|
| 20100129269 | COLLECTING MAIN FOR TUBULAR CRACKING FURNACES - Collecting line for removing hot process gases conducted in process gas tubes from tubular reformers, wherein the collecting line has on the inside at least one insulation layer made of fire-resistant concrete or fire-resistant brick, and on the outside a wall made of a metallic outer tube, comprises a plurality of stubs via which the process gas tubes of the tubular furnace can be connected to the collecting line, wherein in the region of the stubs, the process gas tubes are at least in part conducted in guide tubes, and each gas outlet connected to the respective process gas tube projects into the collecting line, by means of which the process gas is introduced into the collecting line in correct functioning, and at least one gas outlet is constructed as a pipe bend. | 05-27-2010 |
| 20100193741 | PRIMARY REFORMER WITH SECONDARY INLET CHANNELS SUPPLYING THE BURNER - The invention relates to a reactor for catalytic reformation of hydrocarbons with steam at elevated pressure, said reactor comprising a reaction space and a fire space, said reaction space comprised of a multitude of vertical tubes arranged in rows and suitable for being filled with a catalyst, and having facilities for feeding hydrocarbons and steam to be reformed to the reaction space, and furthermore comprising facilities for discharge of reformed synthesis gas from the reaction space, and furthermore comprising a multitude of firing facilities in the upper area of the firing space, said firing facilities being able to generate mainly downwardly directed flames that are suitable to heat the aforementioned reaction tubes, with the tube feeding air to the burner being equipped with a facility for adjusting and setting the air flow, and there being a secondary air feeder mounted additionally to this tube and branching-off from it and configured in various layouts and having an independently controllable facility for adjusting and setting the air flow and also feeding air to the firing device so that a more favorable ratio of fuel gas versus air results at the burners so as to be able to achieve a waste gas poor in nitric oxides. | 08-05-2010 |