Siegrist, CH
Alexander Siegrist, Wettswill CH
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20130203925 | FLAME-RETARDANT MATERIAL COMPRISING A BIOPOLYMER - Flame-retardant material comprising: | 08-08-2013 |
Claire-Anne Siegrist, Geneva CH
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20130039958 | METHOD OF VACCINATION - The present invention relates to improved methods for vaccination of a subject. Particularly, the present invention discloses the use of skin antigen application to amplify and improve a pre-existing immunity against a selected pathogen in a subject. The present invention discloses the use of skin application in combination with conventional vaccination or priming for improved immunization or vaccination of a subject against a selected pathogen. | 02-14-2013 |
Erich Siegrist, Tamins CH
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20110253686 | Laser Processing Machines and Methods - The invention relates to a laser processing machine for selectively processing plate-like or pipe-like workpieces, including: a displacement device to which a workpiece table for supporting a plate-like workpiece can be secured in order to move the workpiece table into and out of a processing range of the laser processing machine and a handling device for handling a pipe-like workpiece when the pipe-like workpiece is processed in the processing range, the handling device having at least one support device for supporting the pipe-like workpiece during the processing operation. The support device can be moved in a controlled manner in the longitudinal direction (X) of the pipe-like workpiece over at least 20% of the processing range. The invention also relates to methods for retrofitting laser processing machines from processing plate-like workpieces to processing pipe-like workpieces. | 10-20-2011 |
Irene Siegrist, Stafa CH
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20100016390 | STABLE, LOW VOC, LOW VISCOUS BIOCIDAL FORMULATIONS AND METHOD OF MAKING SUCH FORMULATIONS - A stable, low VOC, low viscosity biocide formulation comprising an effective amount of at least one biocide, 1,2-benzisothiazolin-3-one (BIT), and a polyglycol liquid carrier of formula (I): R—O-(AO) | 01-21-2010 |
Marco Siegrist, Bonstetten CH
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20090194205 | Bulk Metallic Glass/Graphite Composites - A composite material based on a bulk metallic glass is disclosed. In an amorphous alloy phase forming a substantially continuous matrix, a second phase comprising graphite particles is embedded. The alloy is preferably zirconium based. The particles may have a carbide surface layer, which may be formed phase comprising carbide particles may also be present. The composite material has high plasticity, high yield strength, good elasticity and low coefficient of friction, which renders it a good candidate for applications like joints, frictional bearings or Springs. | 08-06-2009 |
Peter Siegrist, Jegenstorf CH
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20150320254 | PARAMETRIC RECIPES FOR PREPARING BEVERAGE WITH CAPSULES IN A CENTRIFUGAL BREWING SYSTEM - The present invention relates to the preparation of a beverage by centrifugation of a capsule, by: Recognising the type of the capsule inserted in the centrifuging brewing device, and/or its ingredients; Selecting accordingly a recipe comprising at least two sets of target values for parameters of the centrifuging brewing device, each set being associated to a specific condition; Controlling the parameters of the centrifuging brewing device so as to reach the target values of the set associated to the specific condition that is currently met. | 11-12-2015 |
Romain Siegrist, Allschswil CH
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20130065902 | 3-(HETEROARYL-AMINO)-1,2,3,4-TETRAHYDRO-9H-CARBAZOLE DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS - The present invention relates to 3-(heteroaryl-amino)-1,2,3,4-tetrahydro-9H-carbazole derivatives of the formula (I), | 03-14-2013 |
Romain Siegrist, Allschwil CH
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20110086889 | TETRAZOLE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS - The invention relates to tetrazole compounds of formula (I) wherein X, Y, Z, R | 04-14-2011 |
20110105491 | THIAZOLIDINE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS - The invention relates to thiazolidine derivatives of the formula (I) wherein A, B, and R | 05-05-2011 |
20110105514 | 5,6,7,8-TETRAHYDRO-IMIDAZO[1,5-A]PYRAZINE COMPOUNDS - The invention relates to 5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine derivatives of formula (I) wherein R | 05-05-2011 |
20110105515 | TARGETING THE ONCOPROTEIN NUCLEOPHOSMIN - (+)-Avrainvillamide, a naturally occurring alkaloid with antiproliferative activity, is shown to bind to the oncoprotein nucleophosmin. Nucleophosmin is known to regulate the tumor suppressor protein p53 and is overexpressed in many different human tumors. The invention provides methods of modulating nucleophosmin and p53 using (+)-avrainvillamide and analogues thereof. These compounds may provide leads for the development of novel anti-cancer therapies that target nucleophosmin. | 05-05-2011 |
20110166170 | SYNTHESIS OF AVRAINVILLAMIDE, STEPHACIDIN B, AND ANALOGUES THEREOF - The syntheses of the natural products, avrainvillamide and stephacidin B, are provided. The α,β-unsaturated nitrone functionality of avrainvillamide and its 3-alkylidene-3H-indole 1-oxide core is shown to covalently and reversibly bond to heteroatom-based nucleophiles. This capability may allow these molecules to bind active site nucleophiles and may provide the basis for designing potent and selective enzyme inhibitors. Both avrainvillamide and its dimer stephacidin B have been reported to exhibit antiproliferative activity, and avrainvillamide has been reported to exhibit antimicrobial activity against multi-drug resistant bacteria. Avrainvillamide has been found to target cytoskeleton-linking membrane protein (CLIMP-63) thereby preventing cells from undergoing mitosis. The invention provides syntheses of these natural products as well as analogs of these natural products and their functional cores. The compounds of the invention may be used in the treatment of diseases such as cancer, autoimmune diseases, and bacterial infection. | 07-07-2011 |
20110212968 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES - The invention relates to novel phenethylamide derivatives and their wherein A, B, R | 09-01-2011 |
20120088759 | THIAZOLIDIN-4-ONE AND [1,3]-THIAZINAN-4-ONE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS - The present invention relates to thiazolidin-4-one and [1,3]-thiazinan-4-one compounds of formula (I) wherein X, Y, R | 04-12-2012 |
20120101111 | NOVEL OXAZOLIDINONE DERIVIATIVES - The present invention relates to oxazolidinone derivatives of formula (I) wherein Y, R | 04-26-2012 |
20120316178 | PIPERAZINES AS ANTIMALARIAL AGENTS - The invention relates to novel piperazine derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including pharmaceutical compositions containing one or more of those compounds and their use as medicaments for the treatment or prevention of protozoal infections, such as especially malaria. | 12-13-2012 |
20130109685 | 1-PHENYL-SUBSTITUTED HETEROCYCLYL DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS | 05-02-2013 |
20140045870 | 7-(Heteroaryl-Amino)-6,7,8,9-Tetrahydropyrido[1,2-A]Indol Acetic Acid Derivatives and Their Use as Prostaglandin D2 Receptor Modulators - The present invention relates to 7-(heteroaryl-amino)-6,7,8,9-tetrahydropyrido[1,2-a]indol acetic acid derivatives of the formula (I), | 02-13-2014 |
20150158883 | 1-PHENYL-SUBSTITUTED HETEROCYCLYL DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS - The present invention relates to 1-phenyl-substituted heterocyclyl derivatives of the formula (I), | 06-11-2015 |
20150252036 | Heterocyclyl Derivatives and their use as Prostaglandin D2 Receptor Modulators - The present invention relates to phenyl-substituted heterocyclyl derivatives of the formula (I), | 09-10-2015 |
Urs Siegrist, Frick CH
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20100113822 | Preparation of acrylic acid derivatives from alpha- or beta-hydroxy carboxylic acids - The invention is directed to a process for the preparation of α,β-unsaturated acids, esters and amides from α- or β-hydroxycarboxylic acids or esters or precursors in high yields and high selectivity. The α,β-unsaturated acids or esters are optionally prepared in the presence of specific dehydration and/or esterification catalysts. The α,β-unsaturated amides or substituted amides are prepared optionally in the presence of a dehydration and/or amidation catalyst. The source of α- or β-hydroxycarboxylic acids or precusor is preferably from a renewable resource. The precursor is defined herein. | 05-06-2010 |
Walter Siegrist, Visp CH
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20110092711 | CATALYSTS FOR THE PREPARATION OF METHYLPYRIDINE - Subject of the invention is a dehydrogenation catalyst for dehydrogenating methylpiperidine to methylpyridine. Subject of the invention are also methods for preparing the catalysts obtained thereby and methods, in which the catalysts are used. | 04-21-2011 |
20140051569 | CATALYSTS FOR THE PREPARATION OF METHYLPYRIDINE - Subject of the invention is a dehydrogenation catalyst for dehydrogenating methylpiperidine to methylpyridine. Subject of the invention are also methods for preparing the catalysts obtained thereby and methods, in which the catalysts are used. | 02-20-2014 |