Sieczkiewicz
Gregory Sieczkiewicz, Cambridge, MA US
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20140206752 | ENGINEERED NUCLEIC ACIDS AND METHODS OF USE THEREOF FOR NON-HUMAN VERTEBRATES - Provided are formulations, compositions, kits and methods for delivering biological moieties such as modified nucleic acids into cells to induce, reduce or modulate protein expression in non-human vertebrates. | 07-24-2014 |
Gregory J. Sieczkiewicz, Hopkinton, MA US
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20120237975 | ENGINEERED NUCLEIC ACIDS AND METHODS OF USE THEREOF - Provided are compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the use of modified messenger RNAs, and are useful for production of proteins. | 09-20-2012 |
20120269765 | CYTOKINE COMPOSITIONS AND METHODS OF USE THEREOF - Polypeptides, including non-naturally occurring and recombinantly modified polypeptides related to the p19 subunit of IL-23, methods of making such molecules and methods of using such molecules as therapeutic, prophylactic and diagnostic agents are provided. | 10-25-2012 |
Gregory J. Sieczkiewicz, Cambridge, MA US
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20120251618 | DELIVERY AND FORMULATION OF ENGINEERED NUCLEIC ACIDS - Provided are formulations, compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the delivery of biological moieties, and are useful for production of proteins. | 10-04-2012 |
20140371302 | MODIFIED MRNAS ENCODING CELL-PENETRATING POLYPEPTIDES - This invention relates to modified nucleic acid compositions encoding cell-penetrating polypeptides to provoke an innate immune response in a cell and methods of delivering protein-binding partners to target cells. | 12-18-2014 |
20150064725 | ENGINEERED NUCLEIC ACIDS AND METHODS OF USE THEREOF - Provided are compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the use of modified messenger RNAs, and are useful for production of proteins. | 03-05-2015 |
Gregory James Sieczkiewicz, Hopkinton, MA US
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20130064788 | IL-17 FAMILY CYTOKINE COMPOSITIONS AND USES - Binding proteins, including non-naturally occurring and recombinantly modified proteins that bind to an IL-17R and including proteins having a mutated IL-17 cytokine sequence, methods of making such molecules and methods of using such molecules as therapeutic, prophylactic and diagnostic agents are provided. | 03-14-2013 |