Patent application number | Description | Published |
20110256144 | PHARMACEUTICAL COMPOSITION FOR TREATMENT AND PREVENTION OF CANCERS - The present invention relates to a pharmaceutical composition for treatment and/or prevention of cancer, which comprises, as an active ingredient, an antibody or fragment thereof having an immunological reactivity with a CAPRIN-1 protein or a fragment thereof comprising 7 or more consecutive amino acids. | 10-20-2011 |
20120006844 | BUSINESS CARD CASE - A business card case includes a storage case, a fixing part, a lifting part, a guiding part and a discharging button. The storage case comprises a discharging opening for discharging a card, which stores cards in its interior and comprises a lower case and an upper case vertically detachable from each other. The fixing part fixes the lower case and the upper case while both the cases overlap each other. The lifting part provided on the lower case lifts up cards stored in the lower case toward the upper case. The guiding part attached to one of sides of the storage case bends at least of the ones at the top of the cards stored in the lower case. The discharging button slidably provided toward the discharging opening on the upper case includes a locking portion for locking the cards at the top. | 01-12-2012 |
20120097698 | Business Card Case - In order to provide a card case in which cards can be automatically and promptly discharged one by one, the case has a case body capable of accommodating more than one cards inside, a card discharging plate mounted so as to proceed from and retreat into the case body via a card discharging opening provided on a side portion of the case body, with a card being placed on its upper surface, and an elastic piece for movably urging the card discharging plate in one direction. | 04-26-2012 |
20120234855 | BUSINESS CARD CASE - In order to provide a card case in which cards can be securely discharged one by one to the last one, it comprises a storage case which has a card insertion inlet and a card discharging opening, can accommodate several cards inside and comprises a lower case and an upper case; a card push-up piece for pushing up the stored cards as a whole toward the upper case; a card discharging unit with a component with a locking part for locking the uppermost one of the several cards and provided on the upper case so as to be slidable toward the card discharging opening; a guide part provided close to the card discharging opening so as to incline the tip of the card obliquely downward; and a stopper provided close to the card discharging opening so as to prevent the second and lower cards (from the uppermost one) of the several cards from being pushed out of the card discharging opening. | 09-20-2012 |
20120301471 | PHARMACEUTICAL COMPOSITION FOR TREATING AND/OR PREVENTING CANCER - According to the present invention, a cancer antigen protein to be specifically expressed on the surfaces of cancer cells is identified and thus the use of an antibody targeting the cancer antigen protein as an agent for treating and/or preventing a cancer is provided. Specifically, the present invention provides a pharmaceutical composition for treating and/or preventing a cancer, which comprises an antibody or a fragment thereof as an active ingredient having immunological reactivity with a partial polypeptide of CAPRIN-1, wherein CAPRIN-1 is represented by any of the even-numbered sequences of SEQ ID NOS: 2 to 30, and wherein the partial polypeptide comprises the amino acid sequence represented by SEQ ID NO: 37 or an amino acid sequence having 80% or more sequence identity with the amino acid sequence. | 11-29-2012 |
20120301476 | PHARMACEUTICAL COMPOSITION FOR TREATING AND/OR PREVENTING CANCER - According to the present invention, a cancer antigen protein to be specifically expressed on the surfaces of cancer cells is identified and thus the use of an antibody targeting the cancer antigen protein as an agent for treating and/or preventing a cancer is provided. Specifically, the present invention provides a pharmaceutical composition for treating and/or preventing a cancer, which comprises an antibody or a fragment thereof as an active ingredient having immunological reactivity to a partial polypeptide of CAPRIN-1, which is represented by any of even-numbered sequences of SEQ ID NOS: 2 to 30, wherein the polypeptide has the amino acid sequence represented by SEQ ID NO: 37 or an amino acid sequence having 80% or more sequence identity with the amino acid sequence. | 11-29-2012 |
20130045210 | PHARMACEUTICAL COMPOSITION FOR TREATING AND/OR PREVENTING CANCER - According to the present invention, a cancer antigen protein to be specifically expressed on the surfaces of cancer cells is identified and thus the use of an antibody targeting the cancer antigen protein as an agent for treating and/or preventing a cancer is provided. Specifically, the present invention provides a pharmaceutical composition for treating and/or preventing a cancer, which comprises an antibody or a fragment thereof as an active ingredient having immunological reactivity with a partial polypeptide of CAPRIN-1, wherein CAPRIN-1 is represented by any of the even-numbered sequences of SEQ ID NOS: 2 to 30, and wherein the partial polypeptide comprises the amino acid sequence represented by SEQ ID NO: 37 or an amino acid sequence having 80% or more sequence identity with the amino acid sequence. | 02-21-2013 |
20130071398 | PHARMACEUTICAL COMPOSITION FOR TREATING AND/OR PREVENTING CANCER - According to the present invention, a cancer antigen protein to be specifically expressed on the surfaces of cancer cells is identified and thus the use of an antibody targeting the cancer antigen protein as an agent for treating and/or preventing cancer is provided. Specifically, the present invention provides a pharmaceutical composition for treating and/or preventing a cancer, which comprises an antibody or a fragment thereof as an active ingredient having immunological reactivity with a partial polypeptide of CAPRIN-1, which is represented by any of even-numbered sequences of SEQ ID NOS: 2 to 30, wherein the polypeptide has the amino acid sequence represented by SEQ ID NO: 37 or an amino acid sequence having 80% or more sequence identity with the amino acid sequence represented by SEQ ID NO: 37. | 03-21-2013 |
20140193434 | PHARMACEUTICAL COMPOSITION FOR TREATMENT AND/OR PROPHYLAXIS OF CANCER - It is intended to identify a cancer antigenic protein specifically expressed on the surface of cancer cells and to provide an antibody targeting the antigenic protein and use of the antibody as a therapeutic and/or preventive agent for cancer. The present invention provides an antibody or a fragment thereof which has immunological reactivity with a CAPRIN-1 protein, the antibody comprising a heavy chain variable region comprising amino acid sequences of SEQ ID NOs: 5, 6, and 7 and a light chain variable region comprising amino acid sequences of SEQ ID NOs: 9, 10, and 11, and a pharmaceutical composition for treatment and/or prevention of cancer, comprising this antibody or fragment as an active ingredient. | 07-10-2014 |
20140199311 | PHARMACEUTICAL COMPOSITION FOR TREATMENT AND/OR PROPHYLAXIS OF CANCER - This invention provides an antibody targeting a cancer antigenic protein specifically expressed on the surface of cancer cells and use thereof as a therapeutic and/or preventive agent for cancer. More specifically, the present invention provides an antibody, or a fragment thereof which has immunological reactivity with a CAPRIN-1 protein, the antibody comprising a heavy chain variable region comprising complementarity determining regions of SEQ ID NOs: 5, 6, and 7 and a light chain variable region comprising complementarity determining regions of SEQ ID NOs: 9, 10, and 11, and a pharmaceutical composition for treatment and/or prevention of cancer, comprising the same as an active ingredient. | 07-17-2014 |