Shiels
Brian P. Shiels, Charlotte, NC US
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20120171918 | FLAME RESISTANT FABRIC WITH TRACING YARNS - A flame resistant fabric with tracing yarns includes a flame resistant fabric with a first non-tracing yarn, and a second tracing yarn. The first non-tracing yarn and/or the second tracing yarn include flame resistant fibers being selected from the group consisting of inherently flame resistant fibers and treated fibers. When the flame resistant fabric is exposed to heat, flames, long-term excessive UV light, or the like, the first non-tracing yarn is adapted to hold its color and the second tracing yarn is adapted to change colors. | 07-05-2012 |
20140087129 | THERMAL LINER FOR PROTECTIVE GARMENTS - A nonwoven for use in a thermal liner for protective apparel includes 1-45 wt % of a first inherently heat resistant fiber excluding an aramid, and a balance of a second heat resistant fiber. The nonwoven excludes wool and has a thickness less than 3 mm and a basis weight of less than 2.9 osy (100 gsm). In another embodiment, the insulating layer for protective apparel includes a nonwoven including an inherently flame resistant fiber and fibers being inherently resistant to moisture absorption. The inherently flame resistant fiber is different from said inherently resistant to moisture absorption fiber. The nonwoven has an equivalent or better thermal protective performance (TPP) and a lower basis weight than an industry standard nonwoven consisting of a nonwoven of para-aramids or meta-aramids or a blend of both. | 03-27-2014 |
20140290560 | FLAME RESISTANT FABRIC WITH TRACING YARNS - A flame resistant fabric with tracing yarns includes a flame resistant fabric with a first non-tracing yarn, and a second tracing yarn. The first non-tracing yarn and/or the second tracing yarn include flame resistant fibers being selected from the group consisting of inherently flame resistant fibers and treated fibers. When the flame resistant fabric is exposed to heat, flames, long-term excessive UV light, or the like, the first non-tracing yarn is adapted to hold its color and the second tracing yarn is adapted to change colors. | 10-02-2014 |
Brian Patrick Shiels, Charlotte, NC US
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20100297905 | BLEND OF LYOCELL AND FLAME RESISTANT FIBERS FOR PROTECTIVE GARMENTS - A unique blend of fibers used to create a yarn or fabric useful in protective garments including a lyocell fiber, and a flame resistant fiber that is not a modacrylic and/or does not require the emission of gases and/or acids for flame resistance. The lyocell fiber is approximately 5% to 55% of the blend, and the flame resistant fiber is approximately 45% to 95% of the blend. The resulting fabric requires no post treatment for flame resistance. | 11-25-2010 |
Darren James Shiels, Red Deer County CA
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20080263990 | SKIDDING SYSTEM FOR A CATWALK - A skidding system is provided for laterally moving a catwalk. The system can include a plurality of legs placed about the perimeter of the catwalk. Each leg can extend and contract in length. The lower end of each leg can include a trolley member slidably coupled to a foot assembly. The catwalk can be moved laterally by extending the legs to raise the catwalk off of the ground, moving the trolley members within the foot assemblies and then contracting the legs to lower the catwalk to its new position. | 10-30-2008 |
Ian Alexander Shiels, Muirlea AU
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20100267639 | TREATMENT OF OSTEOARTHRITIS - This invention relates to methods of treatment of osteoarthritis, and especially to treatment of this condition with cyclic peptidic and peptidomimetic compounds which have the ability to modulate the activity of G protein-coupled receptors. The compounds preferably act as antagonists of the C5a receptor, and are active against C5a receptors on polymorphonuclear leukocytes and macrophages. Particularly preferred compounds for use in the invention are disclosed. | 10-21-2010 |
20100331236 | CYCLIC PEPTIDES AS G-PROTEIN COUPLED RECEPTOR ANTAGONISTS - The invention relates to novel cyclic compounds which have the ability to modulate the activity of G protein-coupled receptors. The compounds preferably act as antagonists. In preferred embodiments, the invention provides cyclic peptidic and peptidomimetic antagonists of C5a receptors, which are active against C5a receptors on polymorphonuclear leukocytes and macrophages. The compounds of the invention are both potent and selective, and are useful in the treatment of a variety of inflammatory conditions. | 12-30-2010 |
20120302493 | Cyclic Peptides As G-Protein Coupled Receptor Antagonists - The invention relates to novel cyclic compounds which have the ability to modulate the activity of G protein-coupled receptors. The compounds preferably act as antagonists. In preferred embodiments, the invention provides cyclic peptidic and peptidomimetic antagonists of C5a receptors, which are active against C5a receptors on polymorphonuclear leukocytes and macrophages. The compounds of the invention are both potent and selective, and are useful in the treatment of a variety of inflammatory conditions. | 11-29-2012 |
Paul Shiels, Albuquerque, NM US
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20150250672 | LIMB POSITIONING SYSTEM - A limb positioning system includes a clamp assembly, a pylon and bar assembly, a sled assembly, and a limb positioning assembly. The clamp assembly is configured to attach to a bed rail of a surgical table and to accept a pylon connected to a bar. The pylon may have a plurality of pylon bars that are secured by the clamp assembly. A base bar may extend from the pylon, and may be attachable to an extension bar to provide a longer track along which the sled assembly may slide. The sled assembly may be biased to be locked with respect to the base bar. The limb holding assembly may include a boot coupled to the sled via a connector near the heel. The connector may be tapered and insertable into a correspondingly tapered section of a ball that sits within the sled assembly, the ball being capable of polyaxial motion. | 09-10-2015 |
Paul Shiels, Glasgow GB
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20110158961 | MATERIALS AND METHODS RELATING TO CELL BASED THERAPIES - The invention relates to the provision of a novel cell population that can be used for tissue regeneration and the treatment of disease states associated with cell degeneration for age related tissue changes. The cell population are derived from adult stem/progenitor cells which are characterised by being positive or negative to the Thy1.1 cell marker. | 06-30-2011 |
20130143314 | THERAPEUTIC USES OF MICROVESICLES AND RELATED MICRORNAS - The present invention provides improved methods and compositions based on microvesicles for the treatment of various diseases, disorders and conditions. In particular, the present invention encompasses the recognition that microvesicles contain specific microRNAs which may function as intercellular regulators involved in cell or tissue regeneration, remodeling, reconstruction, reprogramming or transdifferentiation. Thus, among other things, the present invention provides methods and compositions based on microvesicles and/or associated microRNAs that provide more predictable and effective therapeutic results. | 06-06-2013 |
20130280219 | MATERIALS AND METHODS RELATING TO CELL BASED THERAPIES - The invention relates to the provision of a novel cell population that can be used for tissue regeneration and the treatment of disease states associated with cell degeneration for age related tissue changes. The cell population are derived from adult stem/progenitor cells which are characterised by being positive or negative to the Thy1.1 cell marker. | 10-24-2013 |
20140234263 | CELLULAR AND MOLECULAR THERAPIES - The present invention provides, among other things, improved compositions and methods for the treatment of tissue damage (e.g., acute or chronic) and related diseases, disorders or conditions based on the use of pathfinder cells, extracellular secretomes thereof, and/or pathfinder cell-associated microRNAs. In some embodiments, the present invention provides a method for treating tissue damage (e.g., acute or chronic) comprising a step of administering a population of cells to an individual suffering from a disease, disorder or condition characterized by acute damage to one or more tissues, wherein the cells are originated from an adult tissue and wherein the cells induce tissue repair, regeneration, remodeling, reconstitution or differentiation. In some embodiments, the present invention provides a method for treating inflammation comprising a step of administering a population of cells, or extracellular secretomes thereof, to an individual suffering from a disease, disorder or condition characterized by inflammation of one or more tissues, wherein the cells are originated from an adult tissue and wherein the cells induce an anti-inflammatory response. | 08-21-2014 |
Paul G. Shiels, Lanarkshire GB
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20090274663 | Materials and Methods Relating to Cell Based Therapies - The invention provides a novel multipotent cell population of adult origin that can be used to treat ageing and disease, particularly by transplantation to site of cellular damage. | 11-05-2009 |
Stefanie Shiels, San Antonio, TX US
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20130330537 | Porous Ceramic Foam Granules and Method of Producing the Same - Materials and methods of producing materials for scaffolds to facilitate growth of bone tissues. Porous ceramic materials are produced by a template coating method. Polymeric foam is processed to produce treated foam. Polymer solution, ceramic powder, dispersant, and drying agent are combined, mixed, and sonicated in a multi-step process to achieve a uniform mixture. In a first coating application, treated foam and ceramic slurry are processed until visibly homogeneous and fully reticulated, then sintered to form porous ceramic materials. Through a second multi-step process, a second ceramic slurry is prepared. In a second coating application, the porous ceramic materials are coated with the second slurry, blocked pores cleared, and the material dried and sintered to form a finalized porous sintered ceramic material. The fully reticulated scaffold material provides ceramic foam scaffolds similar to trabecular bone composition and structure, providing consistent mechanical integrity and porosity for regeneration of functional bone tissues. | 12-12-2013 |