Patent application number | Description | Published |
20140358630 | APPARATUS AND PROCESS FOR CONDUCTING SOCIAL MEDIA ANALYTICS - A system, apparatus and method for performing social media analytics for a movie are provided. The present disclosure provides for a social media analytics platform that builds a rich landscape of interests of movie audiences by mining data from social networking or microblogging services, such as Twitter™. The present disclosure provides for associating at least one user with a movie; collecting, for the at least one associated user, at least one of user location data, user interest data, user-cited website data, and user television viewing habits data from a social networking or microblogging service; processing the collected data to generate movie campaign data, the movie campaign data including at least one of movie marketing data, movie advertising data, and movie distribution data; and providing the at least one movie marketing data, movie advertising data, and movie distribution data for display in a user interface. | 12-04-2014 |
20150177292 | TRACKING ELECTRICAL APPLIANCE USAGE - A system for tracking usage patterns of electrical appliances is disclosed. The system comprises a central database configured to receive and store information; a plurality of energy sensors each of the plurality of sensors being configured to measure a change in electrical energy use by a corresponding one of a plurality of electrical appliances; at least one presence sensor configured to determine when at least one user is proximate to the plurality of electrical appliances and send presence information to the central database; and a processor configured to extract features from such information and create at least one user profile corresponding to the at least one user and a pattern of electrical energy use associated with the at least one user based on said features. | 06-25-2015 |
20150178772 | USER CONTROL OF TARGETED ADVERTISING - A web advertisement classifier for embedded advertisements in a web page includes detecting whether an advertisement is a contextual advertisement; detecting whether the advertisement is a retargeted advertisement; and detecting whether the advertisement is a behaviorally targeted advertisement. Classified advertisement suppression is provided that includes identifying one or more previously-visited web pages; visiting the one or more web pages chronologically identifying one or more target web pages having a content association that is a same content association had by the advertisement; skipping the one or more target web pages; and saving the resultant click stream. | 06-25-2015 |
Patent application number | Description | Published |
20130345780 | Conformally Encapsulated Multi-Electrode Arrays With Seamless Insulation - Thin-film multi-electrode arrays (MEA) having one or more electrically conductive beams conformally encapsulated in a seamless block of electrically insulating material, and methods of fabricating such MEAs using reproducible, microfabrication processes. One or more electrically conductive traces are formed on scaffold material that is subsequently removed to suspend the traces over a substrate by support portions of the trace beam in contact with the substrate. By encapsulating the suspended traces, either individually or together, with a single continuous layer of an electrically insulating material, a seamless block of electrically insulating material is formed that conforms to the shape of the trace beam structure, including any trace backings which provide suspension support. Electrical contacts, electrodes, or leads of the traces are exposed from the encapsulated trace beam structure by removing the substrate. | 12-26-2013 |
20140012284 | VACUUM-ACTUATED PERCUTANEOUS INSERTION/IMPLANTATION TOOL FOR FLEXIBLE NEURAL PROBES AND INTERFACES - A flexible device insertion tool including an elongated stiffener with one or more suction ports, and a vacuum connector for interfacing the stiffener to a vacuum source, for attaching the flexible device such as a flexible neural probe to the stiffener during insertion by a suction force exerted through the suction ports to, and to release the flexible device by removing the suction force. | 01-09-2014 |
20140107446 | FLEXIBLE MICROELECTRODE ARRAY WITH INTEGRATED STIFFENING SHANK, AND METHOD OF FABRICATION - A stiffener-reinforced microelectrode array device and fabrication method having a plurality of polymer layers surroundably encapsulating one or more electrodes connected to one or more metal traces so that the one or more electrodes are exposed. A stiffening shank is also integrally embedded in the polymer layers adjacent an insertion end of the device near the electrodes to provide mechanical support during insertion. | 04-17-2014 |
20140172051 | SINGLE LAYER POLYMER MICROELECTRODE ARRAY - A microelectrode array having one or more electrical conduits surrounded and insulated from each other by only a single layer of polymer (e.g. polyimide), and a method of fabricating the same. Multiple layers of an uncured polymer precursor (such as polyamic acid) are separately formed with metal layers sandwiched in between. Formation of the uncured polymer precursor layers includes deposition and heating to remove solvent only but not polymerize the precursor. Upon completing construction, the array is subjected to a high-temperature curing process that converts the uncured polymer precursor layers into the polymer. The different layers of the polymer precursor are thus covalently bonded together during the curing process to create a single continuous layer (e.g. monolithic block) of polymer, with no polymer-polymer interfaces. | 06-19-2014 |
20140277296 | INCORPORATING AN OPTICAL WAVEGUIDE INTO A NEURAL INTERFACE - An optical waveguide integrated into a multielectrode array (MEA) neural interface includes a device body, at least one electrode in the device body, at least one electrically conducting lead coupled to the at least one electrode, at least one optical channel in the device body, and waveguide material in the at least one optical channel. The fabrication of a neural interface device includes the steps of providing a device body, providing at least one electrode in the device body, providing at least one electrically conducting lead coupled to the at least one electrode, providing at least one optical channel in the device body, and providing a waveguide material in the at least one optical channel. | 09-18-2014 |
20140277317 | FLEXIBLE NEURAL INTERFACES WITH INTEGRATED STIFFENING SHANK - A neural interface includes a first dielectric material having at least one first opening for a first electrical conducting material, a first electrical conducting material in the first opening, and at least one first interconnection trace electrical conducting material connected to the first electrical conducting material. A stiffening shank material is located adjacent the first dielectric material, the first electrical conducting material, and the first interconnection trace electrical conducting material. | 09-18-2014 |
Patent application number | Description | Published |
20140322701 | MINIATURIZED, AUTOMATED IN-VITRO TISSUE BIOREACTOR - In one embodiment, a system includes a bioreactor coupled to a substrate. The bioreactor includes: a plurality of walls defining a reservoir; a plurality of fluidic channels in at least some of the walls; a fluidic inlet in fluidic communication with the reservoir via, the fluidic channels; a fluidic outlet in fluidic communication with the reservoir via the fluidic channels; and one or more sensors coupled to the reservoir, each sensor being configured to detect one or more of: environmental conditions in the reservoir; and physiological conditions of one or more cells optionally present in the reservoir. In another embodiment, a method includes delivering media to a reservoir of a bioreactor; delivering a, plurality of cells to the reservoir, controlling a reservoir temperature and a reservoir gas composition; using one or more of the sensors to monitor environmental and physiological conditions; and reporting the environmental and/or physiological conditions. | 10-30-2014 |
20150050686 | OMNIDIRECTIONAL, MULTIAXIAL BIOPRINTED TISSUE SYSTEM, TECHNIQUES AND APPLICATIONS - A tissue system includes: a support material; and a vascular network comprising a plurality of channels disposed in the support material. A method includes printing a bioink in a support structure to form a network of vascular precursor materials; and converting the vascular precursor materials into a physiologically relevant vascular network. Notably, the tissue systems, networks, etc. are physiologically-relevant, i.e. exhibiting one or more characteristics indicative of physiological relevance, such as a substantially fractal geometry, inter-vessel spacing, cellular composition, dermal structure, concentric multi-layered structure, etc. | 02-19-2015 |
Patent application number | Description | Published |
20090192965 | MODEL-DRIVEN EVENT DETECTION, IMPLICATION, AND REPORTING SYSTEM - An event analysis system monitors information available from both publicly and privately distributed networks of information for events that are relevant to the user's particular business concerns. Those concerns are defined in a customized model of the user's organization and external business environment. The system receives the information, detects events in the information, interprets the events, and determines implications of these events. The detection and implication proceeds with regard to specific entities, relationships between entities, and definitions of the types of events which may occur in the environment in which the entities exist. Accordingly, the analysis system intelligently adapts its processing to recognize and report events which may be of interest for any particular entity. | 07-30-2009 |
20120254088 | MODEL-DRIVEN EVENT DETECTION, IMPLICATION, AND REPORTING SYSTEM - An event analysis system monitors information available from both publicly and privately distributed networks of information for events that are relevant to the user's particular business concerns. Those concerns are defined in a customized model of the user's organization and external business environment. The system receives the information, detects events in the information, interprets the events, and determines implications of these events. The detection and implication proceeds with regard to specific entities, relationships between entities, and definitions of the types of events which may occur in the environment in which the entities exist. Accordingly, the analysis system intelligently adapts its processing to recognize and report events which may be of interest for any particular entity. | 10-04-2012 |
20140095148 | EMOTION IDENTIFICATION SYSTEM AND METHOD - A system and method for identifying emotion in text that connotes authentic human expression, and training an engine that produces emotional analysis at various levels of granularity and numerical distribution across a set of emotions at each level of granularity. The method may include determining similarity between textual data and an emotion, and classifying emotions as similar emotions. | 04-03-2014 |
20140095149 | EMOTION IDENTIFICATION SYSTEM AND METHOD - A system and method for identifying emotion in text that connotes authentic human expression, and training an engine that produces emotional analysis at various levels of granularity and numerical distribution across a set of emotions at each level of granularity. The method may include classifying textual data as emotional textual data or non-emotional textual data, and determining duration of an emotional state. | 04-03-2014 |
20140095150 | EMOTION IDENTIFICATION SYSTEM AND METHOD - A system and method for identifying emotion in text that connotes authentic human expression, and training an engine that produces emotional analysis at various levels of granularity and numerical distribution across a set of emotions at each level of granularity. The method may include producing a chart of data transmissions referenced against time, comparing filtered data transmissions to a database, and selecting a database based on a demographic class of an author. | 04-03-2014 |
Patent application number | Description | Published |
20110103228 | OSPF POINT-TO-MULTIPOINT OVER BROADCAST OR NBMA MODE - A network device identifies an Open Shortest Path First (OSPF) link between the network device and a layer 2 network as one of a point-to-multipoint over broadcast interface or a point-to-multipoint over non-broadcast multi access (NBMA) interface, and performs database synchronization and neighbor discovery and maintenance using one of a broadcast model or a NBMA model. The network device also generates a link-state advertisement for the network device, where the link-state advertisement includes a separate link description for each point-to-point link within the layer 2 network; and sends the link-state advertisement to each fully adjacent neighbor in the layer 2 network. | 05-05-2011 |
20120300620 | FAST RESTORATION FOR PROVIDER EDGE NODE AND ACCESS LINK FAILURES - A first network device creates a protection path to a second network device associated with a first service site, and creates a pseudowire between the first service site and a second service site via the first network device and the second network device. The first network device also detects a failure between the first network device and the first service site, and forwards traffic, provided by the pseudowire between the first service site and the second service site, via the protection path. The second network device uses the traffic on the protection path as a trigger to activate a link between the second network device and the first service site. | 11-29-2012 |
20130003728 | PROVIDING EXTENDED ADMINISTRATIVE GROUPS IN COMPUTER NETWORKS - In general, techniques are described for providing extended administrative groups in networks. A network device comprising an interface and a control unit may implement the techniques. The interface receives a routing protocol message that advertises a link. This message includes a field for storing first data associated with the link in accordance with the routing protocol. The field is defined by the routing protocol as a field having a different function from an administrative group field defined by the same routing protocol. The control unit determines that this field has been repurposed to store second data, wherein this second data specifies an extended administrative group for the link different from those that may be specified by the administrative group field. The control unit then updates routing information to associate the advertised link with the extended administrative group and performs path selection to select paths based on the updated routing information. | 01-03-2013 |
20130083691 | METHODS AND APPARATUS FOR A SELF-ORGANIZED LAYER-2 ENTERPRISE NETWORK ARCHITECTURE - In some embodiments, an apparatus includes a network node operatively coupled within a network. The network node is configured to send a first authentication message upon boot up, and receive, in response to the first authentication message, a second authentication message configured to be used to authenticate the network node. The network node is configured to send a first discovery message, and receive, based on the first discovery message, a second discovery message configured to be used by the network node to identify an address of the network node and an address of a core network node within the network. The network node is configured to set up a control-plane tunnel to the core network node based on the address of the network node and the address for the core network node and receive configuration information from the core network node through the control-plane tunnel. | 04-04-2013 |
20130083782 | METHODS AND APPARATUS FOR A SCALABLE NETWORK WITH EFFICIENT LINK UTILIZATION - In some embodiments, an apparatus comprises a core network node configured to be operatively coupled to a set of network nodes. The core network node is configured to receive a broadcast signal from a network node from the set of network nodes, which is originated from a host device operatively coupled to the network node. The broadcast signal is sent via a tunnel from the network node to the core network node, such that other network nodes that are not included in the tunnel do not receive the broadcast signal. The core network node is configured to retrieve control information associated with the broadcast signal without sending another broadcast signal, and then send the control information to the network node. | 04-04-2013 |
20150156105 | OSPF POINT-TO-MULTIPOINT OVER BROADCAST OR NBMA MODE - A network device identifies an Open Shortest Path First (OSPF) link between the network device and a layer 2 network as one of a point-to-multipoint over broadcast interface or a point-to-multipoint over non-broadcast multi access (NBMA) interface, and performs database synchronization and neighbor discovery and maintenance using one of a broadcast model or a NBMA model. The network device also generates a link-state advertisement for the network device, where the link-state advertisement includes a separate link description for each point-to-point link within the layer 2 network; and sends the link-state advertisement to each fully adjacent neighbor in the layer 2 network. | 06-04-2015 |
Patent application number | Description | Published |
20090086644 | DETECTING DATA PLANE LIVELINESS OF A LABEL-SWITCHED PATH - Detecting if a label-switched path (LSP) is functioning properly. To test that packets that belong to a particular Forwarding Equivalence Class (FEC) actually end their MPLS LSP on an label switching router (LSR) that is an egress for that FEC, a request message carrying information about the FEC whose LSP is being verified may be used. The request message may be forwarded like any other packet belonging to that FEC. A basic connectivity test as well as a fault isolation test are supported. In a basic connectivity test mode, the packet should reach the end of the LSP, at which point it is sent to the control plane of the egress LSR. The LSR then verifies that it is indeed an egress for the FEC. In a fault isolation test mode, the packet is sent to the control plane of each transit LSR, which performs various checks that it is indeed a transit LSR for the LSP. The transit LSR may also return further information that helps check the control plane against the data plane, i.e., that forwarding matches what the routing protocols determined as the path. A reliable return path is used for the reply. | 04-02-2009 |
20100142370 | PROTECTING CONNECTION TRAFFIC USING FILTERS - A connection between network nodes in a communication network is backed up. A failover label-switched path (LSP) is created starting at a first network node of a connection and ending | 06-10-2010 |
20100142548 | METHODS AND APPARATUS FOR USING BOTH LDP AND RSVP IN A COMMUNICATIONS SYSTEM - Methods and apparatus for allowing routers in an autonomous system to implement LDP and RSVP at the same time. RSVP can be used in the network core with LDP being used in network regions surrounding the core. LDP LSPs are tunneled through the RSVP network core using RSVP LSPs and label stacking techniques. During route selection LDP LSPs which use an RSVP LSP tunnel are preferred over alternative LDP LSPs having an equal cost associated with them to create a preference for traffic engineered routes. | 06-10-2010 |
20100296414 | SUPPORTING VIRTUAL PRIVATE NETWORKS USING A FIRST NETWORK TOPOLOGY FOR FORWARDING AND A SUBSET OF THE FIRST NETWORK TOPOLOGY OR A SMALLER TOPOLOGY FOR SIGNALING - Virtual Private Networks (VPNs) are supported in which customers may use popular internet gateway protocol (IGPs) without the need to convert such IGPs, running on customer devices to a single protocol, such as the border gateway protocol (BGP). Scaling problems, which might otherwise occur when multiple instances of an IGP flood link state information, are avoided by using a flooding topology which is smaller than a forwarding topology. The flooding topology may be a fully connected sub-set of the forwarding topology. | 11-25-2010 |
20120020205 | PROTECTING CONNECTION TRAFFIC USING FILTERS - A connection between network nodes in a communication network is backed up. A failover switched path such as a label-switched path (LSP) is created starting at a first network node of a connection and ending at the second node of the connection, while bypassing the protected connection. In the event of connection failure, data is transmitted through the failover switched path (e.g., LSP). A network operator can selectively protect different types of data by using filters that bind one or more types of traffic received over one or more interfaces to different failover switched paths (LSPs). | 01-26-2012 |
Patent application number | Description | Published |
20090252130 | APPARATUS AND METHODS FOR ESTABLISHING CLIENT-HOST ASSOCIATIONS WITHIN A WIRELESS NETWORK - In embodiments, a one-to-one association is established between a client and a host in a wireless network, such as a wireless local area network or a wireless personal communication network. The client may be a display device. The host may be a cellular telephone. Active association corresponds to the host exclusively using a shared resource of the client. When the association is solid, requests from other hosts to establish an active association are denied. When the association is fragile, such requests are granted. In the case of a semi-solid association, a request from another host to establish an active association causes the client to generate a query to the host currently owning the active association. If the host currently owning the association grants a release, a new active association is established between the requesting host and the client. Otherwise, the request from the other host is denied. | 10-08-2009 |
20100150373 | SHARING PUBLIC ADDRESSING SYSTEM USING PERSONAL COMMUNICATION DEVICES IN AN AD-HOC NETWORK - A method, system, and computer program product for using a personal communication device as a microphone in a seminar or conference setting. A client is electrically connected to a PA system and one of many hosts can access the PA system by associating with the client. The association can be transferred by the client or the host. Tokens can be generated for each transfer and a map can be created and stored. | 06-17-2010 |
20100153553 | DYNAMIC RESOURCE SHARING AMONG MULTIPLE WIRELESS DEVICES - A system and method that enables two or more hosts so that they can share a resource, such as a display. Client allocates a portion of the resource to each of the eligible hosts. This allocated size is negotiable among host(s) and the client. Client may request the hosts to scale down/up resource utilization based on the allocated portion of the resource being shared. This helps keep the client implementation simple. In this case, client maintains the allocation vector for each host. This allocation vector is used to keep track of the resource sharing. While this is a preferred approach, it is possible that “intelligent” client may actually modify resource utilization for a given host based on the negotiated allocation. | 06-17-2010 |
20110138018 | MOBILE MEDIA SERVER - Mobile media server (MMS) includes MMS hosts and an MMS clients utilized for ubiquitous sharing of media content. An MMS host, which may be deployed on a mobile terminal such as a cellular telephone, can establish a logical link with an MMS client over an IP interface and initiate a streaming session with the MMS client. The MMS host may further retrieve media content from any source, such as a network source, locally stored content, or a camera and/or microphone on the MMS host, and serve the media content to the MMS client over the logical link. | 06-09-2011 |
20120084652 | 3D VIDEO CONTROL SYSTEM TO ADJUST 3D VIDEO RENDERING BASED ON USER PREFERNCES - 3D image data can be modified based on user preference data received from a user. The user preference data may be received at a first device and used to adjust 3D image data generated by the first device for presentation by a display device, or the first device may receive the user preference data and transmit it to a display device such that the display device may adjust the 3D image data based on the user preference data. The 3D image data may be adjusted based on user preference data to support presentation of 3D imagery on the display device in a manner desired by a user. 3D user viewing preferences may include an amount of pop-out effect in images, a stereo baseline of images, a depth range of images, a spatial distribution of images, a degree of depth sharpness in images, or specification of a user's dominant eye. | 04-05-2012 |
20120269362 | SHARING PUBLIC ADDRESSING SYSTEM USING PERSONAL COMMUNICATION DEVICES IN AN AD-HOC NETWORK - A method, system, and computer program product for using a personal communication device as a microphone in a seminar or conference setting. A client is electrically connected to a PA system and one of many hosts can access the PA system by associating with the client. The association can be transferred by the client or the host. Tokens can be generated for each transfer and a map can be created and stored. | 10-25-2012 |
20120311072 | MULTIPATH MANAGEMENT ARCHITECTURE AND PROTOCOLS FOR MOBILE MULTIMEDIA SERVICE WITH MULTIPLE DESCRIPTION CODING - A wireless communication method includes an aggregator requesting a first description substream of a multimedia service from a source over a first path, receiving confirmation that the source is available, and receiving a first substream of the service. The method includes determining if a quality of the first substream is satisfactory, and requesting to receive the multimedia service over at least one additional path from the same source. A wireless method of communication by a source device includes receiving a multimedia service request from an end device aggregator over a first path, sending an confirmation that the source is available and sending a first substream over the first path in response to the request. The method includes receiving a request to send the multimedia service over at least one additional path to the end device aggregator from the same source. | 12-06-2012 |
20120317300 | MULTIPATH RATE ADAPTATION - An end-to-end multimedia streaming system can include a streaming server and a destination. The streaming server includes a content source, which sends multiple description coding-encoded content over a plurality of paths to the destination. The destination includes an aggregator for aggregating the descriptions from the multiple paths, decoding and recombining them to recover the content. A feedback sender at the destination generates traffic performance variables based on the channel conditions of the multiple paths, and sends these variables to a feedback receiver at the streaming server. The feedback receiver utilizes the feedback information to make adjustments to the transmissions of the content, and to synchronize the transmissions over the multiple paths. | 12-13-2012 |
20130019024 | WIRELESS 3D STREAMING SERVERAANM Sheth; Soham V.AACI San DiegoAAST CAAACO USAAGP Sheth; Soham V. San Diego CA USAANM Raveendran; Vijayalakshimi R.AACI San DiegoAAST CAAACO USAAGP Raveendran; Vijayalakshimi R. San Diego CA USAANM Martinez Bauza; JuditAACI San DiegoAAST CAAACO USAAGP Martinez Bauza; Judit San Diego CA USAANM Bhamidipati; PhaniKumar K.AACI San DiegoAAST CAAACO USAAGP Bhamidipati; PhaniKumar K. San Diego CA USAANM Luo; XunAACI San DiegoAAST CAAACO USAAGP Luo; Xun San Diego CA US - An apparatus, system, method, and computer program product for streaming 3D content from a wireless device to a remote 3D display for the viewing of the 3D content on a larger screen. In some aspects, a wireless streaming server may encode 3D motion picture content in a certain format, where each image frame includes a 2D view concatenated side-by-side with a complementary frame of depth information. The combination of the 2D view and the depth information are capable of being processed by a client display to generate a stereoscopic image representing a 3D view. | 01-17-2013 |
20130066634 | Automated Conversation Assistance - Methods, apparatuses, systems, and computer-readable media for providing automated conversation assistance are presented. According to one or more aspects, a computing device may obtain user profile information associated with a user of the computing device, the user profile information including a list of one or more words that have previously been detected in one or more previously captured speeches associated with the user. Subsequently, the computing device may select, based on the user profile information, one or more words from a captured speech for inclusion in a search query. Then, the computing device may generate the search query based on the selected one or more words. | 03-14-2013 |
20130188632 | SYNCHRONIZED WIRELESS DISPLAY DEVICES - This disclosure relates to techniques for synchronizing playback of media data between a source device and one or more sink devices in a Wireless Display (WD) system. WD systems enable mobile devices to share a local display of the source device with remote sink devices. The techniques of this disclosure include a management procedure at the source device to select a universal queue size for the source device and the participating sink devices. The source device selects the universal queue size based at least on supported queue sizes of the source device and the sink devices. The media packets are then held in queues having the universal queue size at the source device and the sink devices. The uniform queue size combined with compensation for transmission delay enables each of the devices to begin processing the media packets at the same time. | 07-25-2013 |
20130238702 | WIRELESS DISPLAY WITH MULTISCREEN SERVICE - Techniques of this disclosure are generally directed to a method of transmitting content of a first wireless computing device to a second wireless computing device. A first wireless computing device may initiate a WI-FI display (WFD) connection, transmit data from the first wireless computing device via the WFD connection to the second wireless computing device, execute a media sharing application that enables the first wireless computing device to share a media item of a playlist with a wireless client computing device, transmit information that describes the media item of the playlist to the wireless client computing device, wherein transmitting the information that describes the media item causes the second wireless computing device to determine if the wireless client computing device is capable of outputting the media item, and transmit the media item to the wireless client computing device. | 09-12-2013 |
20150023648 | METHOD AND APPARATUS FOR RESOURCE UTILIZATION IN A SOURCE DEVICE FOR WIRELESS DISPLAY - This disclosure relates to techniques for resource utilization in a source device when transmitting video data in a Wireless Display (WD) system. A method for wireless display of compressed content may comprise determining, by a source device, a decoding capability of a sink device, receiving, by the source device, a request to display compressed content at the sink device in a wireless display session, and in the case that the decoding capability of the sink device allows for decoding of the compressed content, transmitting the compressed content from the source device to the sink device, whereby transcoding the compressed content is avoided in the source device. | 01-22-2015 |
Patent application number | Description | Published |
20080221137 | Quinazolines useful as modulators of voltage gated ion channels - The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders. | 09-11-2008 |
20090312342 | Quinazolines useful as modulators of ion channels - The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders. | 12-17-2009 |
20100113508 | Modulators of Cystic Fibrosis Transmembrane Conductance Regulator - The present invention relates to modulators of cystic fibrosis transmembrane conductance regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating diseases using modulators of CFTR. | 05-06-2010 |
20100184739 | Modulators of ATP-Binding Cassette Transporters - The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators. | 07-22-2010 |
20110082117 | PHENYL SULFONAMIDES AS MODULATORS OF ION CHANNELS - The present invention relates to heterocyclic derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders. | 04-07-2011 |
20110124869 | Process for Preparing Modulators of Cystic Fibrosis Transmembrane Conductance Regulator - The present invention relates to processes for preparing solid state forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide, including Compound 1 Form A, Compound 1 Form A-HCl, Compound 1 Form B, and Compound 1 Form B-HCl, any combination of these forms, pharmaceutical compositions thereof, and methods of treatment therewith. | 05-26-2011 |
20110257223 | Modulators of Cystic Fibrosis Transmembrane Conductance Regulator - The present invention relates to modulators of cystic fibrosis transmembrane conductance regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to pharmaceutical compositions comprising a compound of Formula I with one or both of a Compound of Formula II and/or a Compound of Formula III. Further, the present invention relates to methods of treating CFTR mediated diseases, particularly cystic fibrosis, using modulators of CFTR, and compositions and combinations thereof. | 10-20-2011 |
20120178713 | PHENYL SULPHONAMIDES AS MODULATORS OF ION CHANNELS - The present invention relates to phenyl sulfonamides useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders, including for example the treatment of pain. | 07-12-2012 |
20120208841 | Modulators of Cystic Fibrosis Transmembrane Conductance Regulator - The present invention relates to modulators of cystic fibrosis transmembrane conductance regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating diseases using modulators of CFTR. | 08-16-2012 |
20120309758 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS - The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators. | 12-06-2012 |
20130072687 | Process for Preparing Modulators of Cystic Fibrosis Transmembrane Conductance Regulator - The present invention relates to processes for preparing solid state forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide, including Compound 1 Form A, Compound 1 Form A-HCl, Compound 1 Form B, and Compound 1 Form B-HCl, any combination of these forms, pharmaceutical compositions thereof, and methods of treatment therewith. | 03-21-2013 |
20130165442 | Modulators of ATP-Binding Cassette Transporters - The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators. | 06-27-2013 |
20130303570 | Modulators of Cystic Fibrosis Transmembrane Conductance Regulator - The present invention relates to modulators of cystic fibrosis transmembrane conductance regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating diseases using modulators of CFTR. | 11-14-2013 |
20140187787 | PROCESS FOR PREPARING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR - The present invention relates to processes for preparing solid state forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide, including Compound 1 Form A, Compound 1 Form A-HCl, Compound 1 Form B, and Compound 1 Form B-HCl, any combination of these forms, pharmaceutical compositions thereof, and methods of treatment therewith. | 07-03-2014 |
20140303204 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR - The present invention relates to modulators of cystic fibrosis transmembrane conductance regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating diseases using modulators of CFTR. | 10-09-2014 |
20140336393 | PROCESS FOR PREPARING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR - The present invention relates to processes for preparing solid state forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide, including Compound 1 Form A, Compound 1 Form A-HCl, Compound 1 Form B, and Compound 1 Form B-HCl, any combination of these forms, pharmaceutical compositions thereof, and methods of treatment therewith. | 11-13-2014 |
20140343098 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS - The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators. | 11-20-2014 |
Patent application number | Description | Published |
20120040020 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE - The present disclosure relates to pyrazine compounds of formula I: | 02-16-2012 |
20120264749 | MORPHOLINE-SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS - The invention relates to morpholine spirocyclic piperidine amide compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders. | 10-18-2012 |
20130035310 | Piperidine and Piperazine Phenyl Sulfonamides as Modulators of Ion Channels - The present invention relates to piperidine and piperazine phenyl sulfonamides useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders, including for example the treatment of pain. | 02-07-2013 |
20130131107 | PHARMACEUTICAL COMPOSITIONS AND ADMINISTRATIONS THEREOF - The present invention relates to pharmaceutical compositions comprising a compound of Formulas I and II, optionally in combination with a Compound of Formula III and/or a Compound of Formula IV. The invention also relates to solid forms and to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis. | 05-23-2013 |
20130158071 | PHARMACEUTICAL COMPOSITIONS AND ADMINISTRATIONS THEREOF - The present invention relates to pharmaceutical compositions comprising a compound of Formula I in combination with one or both of a Compound of Formula II and/or a Compound of Formula III. The invention also relates to solid forms and to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis. | 06-20-2013 |
20140113005 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE - The present disclosure relates to pyrazine compounds of formula I: | 04-24-2014 |
20150025073 | MORPHOLINE-SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS - The invention relates to morpholine spirocyclic piperidine amide compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders. | 01-22-2015 |