Sheldrake, GB
Colin David Sheldrake, Oxfordshire GB
Patent application number | Description | Published |
---|---|---|
20090293873 | POWDER DELIVERY DEVICES - A nasal delivery device for delivering substance to a nasal cavity of a subject, the delivery device comprising: a substance supply unit for supplying a dose of substance to be delivered to the nasal cavity of the subject, she substance supply unit including an inlet and an outlet; a nosepiece unit including a nosepiece for fitting to a nasal cavity of the subject and being in fluid communication with the outlet of the substance supply unit; and a mouthpiece unit including a mouthpiece in fluid communication with the inlet of the substance supply unit and through which the subject in use exhales such as to entrain substance from the container chamber and deliver the same through the nosepiece, and at least one temperature modifier for reducing a temperature of the exhaled air flow such as to reduce the absolute humidity thereof. | 12-03-2009 |
Colin David Sheldrake, Wiltshire GB
Patent application number | Description | Published |
---|---|---|
20100057047 | DELIVERY DEVICE AND METHOD - A nasal delivery device for and method of delivering substance to the middle meatus in a nasal cavity of a subject in the treatment of a condition, in particular an inflammatory or infectious condition, thereof, the delivery device comprising: a nosepiece unit ( | 03-04-2010 |
20100282246 | NASAL DELIVERY - A nasal delivery device for and method of delivering substance to a nasal cavity of a subject, the delivery device comprising: a nosepiece ( | 11-11-2010 |
20100300439 | NASAL DELIVERY DEVICES - A nasal delivery device for and method of delivering particulate substance to the nasal airway of a subject, the delivery device comprising: a body assembly ( | 12-02-2010 |
20110088690 | NASAL DELIVERY DEVICES - A nasal delivery device for and a method of delivering substance to a nasal airway of a subject, the nasal delivery device comprising : a mouthpiece ( | 04-21-2011 |
20130098362 | Nasal Delivery Devices - A nasal delivery device for and method of delivering substance to a nasal cavity of a subject, the delivery device comprising: a container-receiving unit comprising a container chamber for receiving a substance-containing container which contains substance to be delivered to the nasal cavity of the subject, the container chamber including an inlet and an outlet; a nosepiece unit including a nosepiece for fitting to a nasal cavity of the subject and being in fluid communication with the outlet of the container chamber; a mouthpiece unit including a mouthpiece in fluid communication with the inlet of the container chamber and through which the subject in use exhales, such as to entrain substance from the container and deliver the same through the nosepiece; and moisture-mitigation means for mitigating an effect of moisture in an exhaled breath on the entrainment of substance from the container. | 04-25-2013 |
20140041660 | NASAL DELIVERY DEVICES - A nasal delivery device for and method of delivering substance to a nasal cavity of a subject, the delivery device comprising: a container-receiving unit comprising a container chamber for receiving a substance-containing container which contains substance to be delivered to the nasal cavity of the subject, the container chamber including an inlet and an outlet; a nosepiece unit including a nosepiece for fitting to a nasal cavity of the subject and being in fluid communication with the outlet of the container chamber; a mouthpiece unit including a mouthpiece in fluid communication with the inlet of the container chamber and through which the subject in use exhales, such as to entrain substance from the container and deliver the same through the nosepiece; and moisture-mitigation means for mitigating an effect of moisture in an exhaled breath on the entrainment of substance from the container, which means are provided, for example, by providing the container in a replaceable container-containing member, by a pressure-sensitive valve which normally closes the fluid connection between the container chamber and the mouthpiece, and a temperature regulator upstream of the container chamber. | 02-13-2014 |
20150101605 | POWDER DELIVERY DEVICES - A nasal delivery device for delivering substance to a nasal cavity of a subject, the delivery device comprising: a substance supply unit for supplying a dose of substance to be delivered to the nasal cavity of the subject, the substance supply unit including an inlet and an outlet; a nosepiece unit including a nosepiece for fitting to a nasal cavity of the subject and being in fluid communication with the outlet of the substance supply unit; and a mouthpiece unit including a mouthpiece in fluid communication with the inlet of the substance supply unit and through which the subject in use exhales such as to entrain substance from the container chamber and deliver the same through the nosepiece, and at least one temperature modifier for reducing a temperature of the exhaled air flow such as to reduce the absolute humidity thereof. | 04-16-2015 |
Colin David Sheldrake, Swindon GB
Patent application number | Description | Published |
---|---|---|
20080289629 | Nasal Delivery Devices - A nasal delivery device for and method of delivering substance to a nasal cavity of a subject, the delivery device comprising: a container-receiving unit comprising a container chamber for receiving a substance-containing container which contains substance to be delivered to the nasal cavity of the subject, the container chamber including an inlet and an outlet; a nosepiece unit including a nosepiece for fitting to a nasal cavity of the subject and being in fluid communication with the outlet of the container chamber; a mouthpiece unit including a mouthpiece in fluid communication with the inlet of the container chamber and through which the subject in use exhales, such as to entrain substance from the container and deliver the same through the nosepiece; and moisture-mitigation means for mitigating an effect of moisture in an exhaled breath on the entrainment of substance from the container, which means are provided, for example, by providing the container in a replaceable container-containing member, by a pressure-sensitive valve which normally closes the fluid connection between the container chamber and the mouthpiece, and a temperature regulator upstream of the container chamber. | 11-27-2008 |
Peter Sheldrake, London GB
Patent application number | Description | Published |
---|---|---|
20150218181 | PHARMACOLOGICALLY ACTIVE COMPOUNDS - The present invention relates to compounds of formula II | 08-06-2015 |
Peter William Sheldrake, Sutton GB
Patent application number | Description | Published |
---|---|---|
20130345181 | PYRROLOPYRIDINEAMINO DERIVATIVES AS MPS1 INHIBITORS - The present invention relates to the use of certain pyrrolopyridineamino derivatives (hereinafter referred to as “PPA derivatives”), particularly 1H-pyrrolo[3,2-c]pyridine-6-amino derivatives, to inhibit the spindle checkpoint function of Monospindle 1 (Mps1—also known as TTK) kinases either directly or indirectly via interaction with the Mps kinase itself. In particular, the present invention relates to PPA derivatives for use as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of the PPA derivatives, and pharmaceutical compositions comprising them. Formula (I) | 12-26-2013 |
Peter William Sheldrake, Kent GB
Patent application number | Description | Published |
---|---|---|
20100093769 | COMPOUNDS - The present invention relates to compounds of formula (I) | 04-15-2010 |
Ross Sheldrake, Otley GB
Patent application number | Description | Published |
---|---|---|
20130031919 | REFRIGERATION PLANT AND METHODS OF CONTROL THEREFOR - A refrigeration plant has a refrigerator circuit comprising a compressor, a condensing coil, an expansion valve and an evaporator. Heat is absorbed in the evaporator and exhausted at the condenser. Pressure is measured at the compressor inlet and a blower arrangement for blowing cool air over a heat transfer surface of the condenser is controlled in dependence upon the pressure measurement. | 02-07-2013 |
Terence Sheldrake, Sunderland GB
Patent application number | Description | Published |
---|---|---|
20090000683 | Flexible pipe - Apparatus and methods are disclosed relating to flexible pipe and composite tape. Flexible pipe body for a flexible pipe comprises an internal pressure sheath and at least one armour layer over the sheath comprising a wound tape of composite material. A method for manufacturing a composite tape is disclosed making use of a pultrusion process. | 01-01-2009 |
20100146768 | FLEXIBLE PIPE - Apparatus and methods are disclosed relating to flexible pipe and composite tape. Flexible pipe body for a flexible pipe comprises an internal pressure sheath and at least one armour layer over the sheath comprising a wound tape of composite material. A method for manufacturing a composite tape is disclosed making use of a pultrusion process. | 06-17-2010 |
Terence Sheldrake, Billingham GB
Patent application number | Description | Published |
---|---|---|
20120273082 | FLEXIBLE PIPE INCLUDING THERMAL INSULATION - Apparatus for providing a thermal insulation layer in a flexible pipe, including one or more encapsulated regions of aerogel material disposed in a layer of flexible pipe body is disclosed. In addition, flexible pipe body including such apparatus, and a method of manufacturing flexible pipe body is disclosed. | 11-01-2012 |
Terence Henry Sheldrake, Billingham GB
Patent application number | Description | Published |
---|---|---|
20130134617 | FLEXIBLE PIPE - Apparatus and methods are disclosed relating to flexible pipe and composite tape. Flexible pipe body for a flexible pipe comprises an internal pressure sheath and at least one armour layer over the sheath comprising a wound tape of composite material. A method for manufacturing a composite tape is disclosed making use of a pultrusion process. | 05-30-2013 |
Terence Henry Sheldrake, Newcastle-Upon-Tyne GB
Patent application number | Description | Published |
---|---|---|
20130299033 | FLEXIBLE PIPE BODY WITH BUOYANCY ELEMENT AND METHOD OF PRODUCING SAME - A flexible pipe body and method of producing a flexible pipe body are disclosed. The flexible pipe body includes an inner fluid retaining layer; an armour layer provided radially outwards of the inner fluid retaining layer; and a buoyancy layer including a plurality of discrete elongate buoyancy elements provided radially outwards of the fluid retaining layer wound at a helical pitch angle equal to or more than 0 degrees and less than about 85 degrees to the longitudinal axis of the flexible pipe body. | 11-14-2013 |
Terence Henry Sheldrake, Sunderland GB
Patent application number | Description | Published |
---|---|---|
20090151789 | HEAT DISSIPATION - A method and apparatus are disclosed for dissipating heat from a region of flexible pipe covered by a bend stiffener. The method includes the steps of, via at least one channel in an outer surface around a flexible pipe, providing a flow path for water to flow from a region of the flexible pipe covered by a bend stiffener to an uncovered region of the flexible pipe. | 06-18-2009 |