Shahinian
Arda Shahinian, Markham CA
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20110059068 | POLYPEPTIDES INVOLVED IN IMMUNE RESPONSE - Polypeptides which comprise a receptor-ligand pair involved in T-cell activation are disclosed. Nucleic acid molecules encoding the polypeptides, and vectors and host cells for expressing the polypeptides are also disclosed. The polypeptides, or agonists and antagonists thereof, are used to treat T-cell mediated disorders. | 03-10-2011 |
20140004129 | Novel Polypeptides Involved in Immune Response | 01-02-2014 |
Hrayr Karnig Shahinian, Pasadena, CA US
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20100241047 | System, Methods and Apparatus for Cerebral Protection - A device, system and method for perfusing an oxygenated medium in the cerebral vasculature. In the case of bihemispheric brain perfusion, it includes positioning pressure cuffs on upper extremities; providing a catheter having a multi-region configuration with a balloon; inserting the catheter into a subclavian or femoral vein; advancing the catheter such that the balloon is positioned substantially in the superior vena cava junction substantially proximal to the take-off of the left innominate vein. During a perfusion mode, the cuffs and balloon are inflated causing an increase in cerebral blood flow, retrogradely; and oxygenated blood which may be cooled is pumped from a femoral artery into the catheter for a suitable period. During a non-perfusion mode the cuffs and balloon are deflated. The catheter has at least two regions, namely, guide wire and fluid delivery regions. Optionally, a separate balloon inflation region may be provided. In the case of unilateral (single hemisphere) brain perfusion, it includes providing a catheter having a multi-region configuration with a balloon, inserting the catheter into a subclavian, jugular or femoral vein, advancing the catheter such that the balloon is positioned in the internal jugular vein on the side ipsilateral to the side of the brain requiring perfusion. In this unilateral scenario where the balloon is inflated in the ipsilateral internal jugular vein, no pressure cuffs are needed and only the balloon is inflated and deflated during the perfusion and non-perfusion modes respectively. | 09-23-2010 |
Hrayr Karnig Shahinian, Beverly Hills, CA US
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20090187072 | ENDOSCOPE AND SYSTEM AND METHOD OF OPERATION THEREOF - An endoscope including a rigid section having opposed first and second ends and an opening situated between the first and second ends, the rigid section defining a longitudinal axis; a handle portion coupled to a first end of the rigid section and having first and second scissor-type handles suitable for grasping by a user; and a base part situated at the second end of the rigid section and coupled to the first handle of the scissor-type handles such that displacement of the first handle causes a rotation of the base part. | 07-23-2009 |
20110115882 | STEREO IMAGING MINIATURE ENDOSCOPE WITH SINGLE IMAGING CHIP AND CONJUGATED MULTI-BANDPASS FILTERS - A dual objective endoscope for insertion into a cavity of a body for providing a stereoscopic image of a region of interest inside of the body including an imaging device at the distal end for obtaining optical images of the region of interest (ROI), and processing the optical images for forming video signals for wired and/or wireless transmission and display of 3D images on a rendering device. The imaging device includes a focal plane detector array (FPA) for obtaining the optical images of the ROI, and processing circuits behind the FPA. The processing circuits convert the optical images into the video signals. The imaging device includes right and left pupil for receiving a right and left images through a right and left conjugated multi-band pass filters. Illuminators illuminate the ROI through a multi-band pass filter having three right and three left pass bands that are matched to the right and left conjugated multi-band pass filters. A full color image is collected after three or six sequential illuminations with the red, green and blue lights. | 05-19-2011 |
20130096381 | ENDOSCOPE AND SYSTEM AND METHOD OF OPERATION THEREOF - An endoscope including a rigid section having opposed first and second ends and an opening situated between the first and second ends, the rigid section defining a longitudinal axis; a handle portion coupled to a first end of the rigid section and having first and second scissor-type handles suitable for grasping by a user; and a base part situated at the second end of the rigid section and coupled to the first handle of the scissor-type handles such that displacement of the first handle causes a rotation of the base part. | 04-18-2013 |
20140085420 | PROGRAMMABLE SPECTRAL SOURCE AND DESIGN TOOL FOR 3D IMAGING USING COMPLEMENTARY BANDPASS FILTERS - An endoscopic illumination system for illuminating a subject for stereoscopic image capture, the illumination system includes a light source which outputs multi-spectral light; first and second light paths configured to transmit the multi-spectral light; and a digital mirror array (DMA) which receives the multi-spectral light and directs the multi-spectral light to a selected one of the first and second light paths. A controller controls the DMA to direct the multi-spectral light to the selected light path in accordance with a time-multiplexing scheme; and/or first and second complementary multiband bandpass filters (CMBF). The first CMBF may be situated in the first light path and the second CMBF may be situated in the second light path, where the first and second CMBFs filter the multi-spectral light incident thereupon to output filtered light. | 03-27-2014 |
Levon Shahinian, Midland, MI US
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20150080596 | Method Of Reducing A Halosilane Compound In A Micoreactor - A method of producing a hydrosilane compound in a microreactor comprises reducing a halosilane compound in the microreactor and in the presence of a reducing agent to produce the hydrosilane compound. | 03-19-2015 |
Rachel Shahinian, Alameda, CA US
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20090081661 | Alkyl amines improve detection of components of formaldehyde-fixed biological samples - Alkyl amines act to release formaldehyde cross-linking that occurs in biological samples. Thus, contacting alkyl amines to formaldehyde fixed samples is a useful way to render biological components of the samples, including nucleic acids or proteins, more accessible to detection and characterization. | 03-26-2009 |
20110294168 | DNA POLYMERASES AND RELATED METHODS - Disclosed are mutant DNA polymerases having improved extension rates relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. The mutant polymerases overcome the inhibitory effects of a variety of polymerase and reverse transcriptase inhibitors. Therefore, the mutant polymerases are useful in a variety of disclosed methods in the presence of such inhibitors. | 12-01-2011 |
20120258501 | DNA POLYMERASES WITH IMPROVED ACTIVITY - Disclosed are DNA polymerases having increased reverse transcriptase efficiency, mismatch tolerance, extension rate and/or tolerance of RT and polymerase inhibitors relative to a corresponding, unmodified polymerase. The polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the DNA polymerases. | 10-11-2012 |
20140120547 | ALKYL AMINES IMPROVE DETECTION OF COMPONENTS OF FORMALDEHYDE-FIXED BIOLOGICAL SAMPLES - Alkyl amines act to release formaldehyde cross-linking that occurs in biological samples. Thus, contacting alkyl amines to formaldehyde fixed samples is a useful way to render biological components of the samples, including nucleic acids or proteins, more accessible to detection and characterization. | 05-01-2014 |
Razmik Shahinian, Los Angeles, CA US
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20090125248 | System, Method and computer program product for integrated analysis and visualization of genomic data - Described is a system for analysis and visualization of genomic data. The system allows a user to select at least one individual sample. The sample has chromosomal data representing a genome with a chromosome and also includes chromosomal measurements of at least one event at a particular location on the chromosome. A frequency of event is generated based on the selected sample. The frequency of event is a frequency of occurrence of the event in the selected sample. At least one annotation can be selected that includes chromosomal region specific information as related to the chromosome. Finally, the chromosomal data, the annotation, and the frequency of event on a display can all be simultaneously displayed, thereby allowing a user to view chromosomal region specific information with respect to a particular chromosomal event. | 05-14-2009 |
Rod Shahinian, Los Angeles, CA US
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20090037332 | Systems and Methods for Processing Banking Transactions - A system and method for providing an efficient and robust interface that allows banking transactions to be processed by an online banking system and third party accounting software packages via a single user point of entry. The system is configured to receive a transaction request from a third party accounting software, the transaction request including one or more transactions; verify, based on information stored in a first database, that the transaction request is from a valid source; store information regarding the one or more transactions from the transaction request in a second database; process the one or more transactions; and provide a response to the third party accounting software indicating a status of at least one transaction in the transaction request. | 02-05-2009 |