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Semba

Charles Semba, Palo Alto, CA US

Patent application numberDescriptionPublished
20090155176Compositions and methods for treatment of diabetic retinopathy - The present invention provides compounds and methods for the treatment of diabetic retinopathy. In particular, LFA-1 antagonists are described herein to be used in the treatment of diabetic retinopathy. One aspect of the invention provides for diagnosis of diabetic retinopathy and administration of a LFA-1 antagonist, after the patient is diagnosed with diabetic retinopathy.06-18-2009

Patent applications by Charles Semba, Palo Alto, CA US

Charles P. Semba, Palo Alto, CA US

Patent application numberDescriptionPublished
20100330083PLASMINOGEN ACTIVATOR VARIANT FORMULATIONS - A solution is provided comprising about 0.01-0.05 mg/mL of tenecteplase in sterile water for injection or bacteriostatic water for injection and normal saline. Such solution is useful for delivery from a catheter and for treating a thrombotic disorder by exposing fibrin-rich fluid from the disorder to an effective amount thereof, as well as in kits. In a preferred embodiment, peripheral thrombosis is treated in a mammal comprising delivering to the mammal via a catheter an effective amount of this solution.12-30-2010

Patent applications by Charles P. Semba, Palo Alto, CA US

Richard David Semba, Baltimore, MD US

Patent application numberDescriptionPublished
20110319499Methods for the Detection of Advanced Glycation Endproducts and Markers for Disease - The present invention provides compositions and methods for detecting carboxymethyl-lysine (CML) and circulating receptor for advanced glycation end (RAGE) products, and methods for correlating CML and RAGE levels with age-related disease, hi particular, serum CML and/or circulating receptor for advanced glycation end (RAGE) products can be used as a clinical biomarker in diagnostics to identify people who are at a higher risk of developing adverse ageing-related outcomes.12-29-2011

Tetsuo Semba, San Jose, CA US

Patent application numberDescriptionPublished
20100067342APPARATUS AND METHOD FOR ADJUSTING A FEED-FORWARD SIGNAL FOR SEEK CONTROL DURING A SEEK OPERATION - A hard disk drive control module has a feed-forward signal input port communicatively coupled with a reference model. The hard disk drive control module has a tracking error signal input port communicatively coupled with a magnetic transducer of the hard disk drive. The hard disk drive control module has an error calculator module configured for determining a difference between an estimated tracking error signal in response to a first feed-forward signal and an actual tracking error signal of the magnetic transducer in response to the first feed-forward signal. The hard disk drive control module has a feed-forward signal adjuster module configured for adjusting a gain and a phase for a second feed-forward signal based on the difference between the estimated tracking error signal in response to the first feed-forward signal and the actual tracking error signal of the magnetic transducer. The hard disk drive control module has a feed-forward signal adjustment output port communicatively coupled to the second feed-forward signal.03-18-2010
20100067357MAGNETIC RECORDING DISK DRIVE WITH ROTATIONAL VIBRATION COMPENSATION HAVING ADAPTIVE OPTIMIZATION OF VIBRATION SENSOR GAINS - A disk drive and a method for operating the disk drive compensates for rotational vibration (RV) by adaptively modifying the gains of two separate linear vibration sensors so the sensor gains are optimal under any given condition. The two sensors provide two signals S03-18-2010

Patent applications by Tetsuo Semba, San Jose, CA US

Yoshiki Semba, Montgomery, AL US

Patent application numberDescriptionPublished
20110214621HIGH EFFICIENCY GAS-FIRED WATER HEATER - The efficiencies of illustrative embodiments of vertical center flue type fuel-fired base water heaters are improved by installing in the water heaters variously configured tubular condensing type secondary heat exchangers of smaller diameters than the associated center flues. The efficiency increases are achieved with components and manufacturing processes similar to those utilized in the base water heaters and secondary heat exchanger materials similar to those in the tank portions of the base water heaters.09-08-2011