Scott, TN
Andrew Scott, Smyma, TN US
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20130228650 | LIGHTWEIGHT WEAPONS PLATFORM - A mounting system is provided including a center platform having a plurality of mounting lugs for mounting the center platform transversely extending at least partially through an aircraft cabin with a first end and second end of the center platform adjacent a respective first and second side opening of the aircraft cabin. A first support pylon may be removably coupleable to the first end of the center platform to extend outwardly from a first side of the aircraft. A second support pylon may be removably coupleable to the second end of the center platform to extend outwardly form a second side of the aircraft. A modular floor component may be removably coupleable relative to a longitudinal side of the center platform to provide a substantially planar load surface including a top portion of the modular floor component and a top surface of the center platform. | 09-05-2013 |
Avery Scott, Knoxville, TN US
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20130337928 | Golf Mat Training Aid - A golf training aid with indicia that directs a golfer to the proper address and impact positions for more accurate shots. The training mat allows a user to learn and develop muscle memory to the basics of how to compress a golf ball. In some of its many embodiments, the present general inventive concept comprises a golf practice mat/towel that provides indicia showing the proper foot stance, ball position and the appropriate club shaft position with respect to different types of golf clubs. | 12-19-2013 |
Daniel C. Scott, Memphis, TN US
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20140179593 | METHODS AND COMPOSITIONS FOR INHIBITING NEDDYLATION OF PROTEINS - Provided herein is a novel binding pocket within NEDD8 co-E3 proteins that binds NEDD8 E2 enzymes. Particularly at its M-Terminus. Methods are provided for screening for compounds that bind to the disclosed E2-binding pocket in NEDD8 co-E3 proteins. Compounds that bind to the E2-binding pocket and optionally inhibit the activity of NEDD8 co-E3 proteins and pharmaceutical compositions comprising the same are further provided. The NEDD8 co-E3 inhibitors find use, as agents preventing the NEDDylation of a target protein, in inhibiting cell growth and methods for treating cancers, inflammatory disorders, and pathogenic infections. The preferred inhibitors are peptides corresponding to a M-terminal fragment of Dnc1, e.g. MTLASKLKRDD, MLKLRQLQKKKQ, and MIKLFSLKQQKK, which are substituted at the M-Terminus with an uncharged group (e.g. acyl). | 06-26-2014 |
David H. Scott, Bristol, TN US
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20110114279 | Insulated Investment Casting Mold and Method of Making - An insulated investment casting shell mold is made by first mixing at least one refractory material with a slurry vehicle forming a prime coat slurry, and optionally mixing at least one refractory material with a slurry vehicle forming a backup slurry. The prime slurry is coated onto a fugitive pattern and optionally dried and/or stuccoed wherein the stucco has at least one refractory material. Optionally, at least one coat of the backup slurry is applied to the prime coated fugitive pattern and optionally dried and/or stuccoed after each coat of the backup slurry. The backup and stucco may be applied a plurality of times to obtain a desired shell wall thickness. An insulating slurry is formed by introducing gas into a slurry vehicle having at least one refractory material and containing a stabilizer and a foaming agent wherein gaseous bubbles become entrained therein forming an insulating slurry having closed porosity therein. The insulating slurry is coated onto at least one portion of the pattern after the prime coat and preferably at least a portion of the outermost layer of a backup coated pattern has the insulating slurry thereon. | 05-19-2011 |
James Edward Scott, Franklin, TN US
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20130028447 | MUSICAL INSTRUMENT MASTER VOLUME AMPLIFIER - A circuit and method for decoupling the perceived tone and volume of an amplified musical signal, such as a guitar amplifier, and allowing for the operator to achieve the desired sonic tone, texture and dynamic feel while separately controlling the overall perceived volume level of the amplifier device. | 01-31-2013 |
20140219477 | GUITAR AMPLIFIER - A system and method for a guitar amplifier that overcomes the disadvantages of known amplified speaker enclosures and circuits while providing more effective volume control. A venue switch selects different output ranges for the guitar amplifier. Volume control still adjusts output regardless of venue switch position. In the low-output setting for the venue switch a house or other quiet venue is accommodated with the guitar amplifier that can work in larger venues in the high-output setting. | 08-07-2014 |
Marcus L. Scott, Memphis, TN US
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20100074789 | MEDICAL IMPLANTS HAVING A POROUS COATED SUFACE - A process for making a diffusion hardened medical implant having a porous surface is disclosed. The medical implant is made by a hot isostatic pressing process which simultaneously forms that porous surface and the diffusion hardened surface. | 03-25-2010 |
20110008407 | COATING AND COATING METHOD - The present invention discloses a coating for a medical implant, wherein at least a part of said coating contains an osseointegration agent and the same and/or a different part of the coating contains an antimicrobial metal agent. | 01-13-2011 |
20110014258 | GRADIENT COATING FOR BIOMEDICAL APPLICATIONS - The present invention provides a coating comprising a bioactive material and an antimicrobial agent, wherein the concentration of said antimicrobial agent varies throughout the thickness of the coating. | 01-20-2011 |
20110159053 | PREPARATION OF A CELL CONCENTRATE FROM A PHYSIOLOGICAL SOLUTION - The present invention is directed to methods and compositions regarding the preparation of an cell concentrate, such as, for example, an osteogenic cell concentrate, from a physiological solution, such as bone marrow aspirate, blood, or a mixture thereof. In specific embodiments, the invention provides methods and compositions utilizing two physiological solution-processing techniques, particularly in a point of care environment, wherein centrifugation is not employed. | 06-30-2011 |
20150056264 | Coating and Coating Method - The present invention discloses a coating for a medical implant, wherein at least a part of said coating contains an osseointegration agent and the same and/or a different part of the coating contains an antimicrobial metal agent. | 02-26-2015 |
Nathan Scott, Loudon, TN US
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20130205693 | PIPE FLASHING PROTECTOR - A pipe flashing protector for protecting the vulnerable joint between a vent pipe and the roof flashing for a building, house or other architectural structure to prevent wear and decay of the joint and more specifically to protect the joint from ultraviolet light, moisture, and debris. | 08-15-2013 |
Robert E. Scott, Memphis, TN US
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20150252409 | SYSTEMS GENETICS NETWORK REGULATORS AS DRUG TARGETS - The present invention provides for methods, processes and platforms to validate systems genetics networks to define their genetic regulators and to optimize translational applicability to humans for drug development. These systems genetics networks are sets of genes with a common function that demonstrate covariate expression that is genetically modulated by linked function network regulators (LFNRs) which comprise eQTLs in animals and GWAS SNPs in humans. LFNRs represent a new class of targets to identify drugs to prevent, ameliorate, and/or treat human diseases. LFNRs for the cell cycle-mitosis network have potential to be especially useful for anti-cancer therapies. The present invention provides for a drug that targets a specific LFNR for the cell cycle-mitosis network in Caucasian male liver to prevent the development of hepatocellular carcinoma in high risk patient populations. | 09-10-2015 |
Sarah A. Scott, Nashville, TN US
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20120214832 | ISOFORM SELECTIVE PHOSPHOLIPASE D INHIBITORS - Disclosed are isoform selective Phospholipase D inhibitors. In one aspect, the disclosed compounds can have a structure represented by a formula (I): Also disclosed are methods of making and using the compounds. Also disclosed are pharmaceutical compositions and kits comprising the compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. | 08-23-2012 |
Sharon Scott, Lebanon, TN US
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20100089331 | Livestock feeder with breakaway capability - A livestock feeder is provided wherein the seams of the feeder are detachable/re-attachable so as to break away from the livestock in case of entanglement. The break away feature may be applied to various configurations of livestock feeders. The breakaway feature is provided so as to avoid injury to the livestock and also make the livestock feeders easier to clean. Seam attachment means include, but are not limited to, hook and loop fasteners, adhesives, zippers, snaps or buttons. | 04-15-2010 |
Timothy Scott, Knoxville, TN US
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20110071217 | Process for the Synthesis of 4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo-3H-spiro[isoben- zofuran-1,9'-xanthen]-3-one (Rose Bengal) and Related Xanthenes - A new process for the manufacture of iodinated xanthenes in high purity includes a cyclization step followed by an iodination step. No extraction, chromatographic or solvent concentration steps are required, and the intermediate as well as final compounds are isolated via filtration or similar means. The process requires a single organic solvent, and the steps are completed at temperatures below 100° C. The exclusion of chloride ions, of chloride free-radicals, hypochlorite ions, or hypochlorous acid as reagents or from reagents that may generate these species in situ in the presence of oxidants, prevents undesirable impurity formation. Several new compounds have been conceived and isolated using these methods. These new compounds are also formed into new medicaments. | 03-24-2011 |
20130274322 | Process for the Synthesis of 4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo-3H-spiro[isoben- zofuran-1,9'-xanthen]-3-one(Rose Bengal) and Related Xanthenes - A new process for the manufacture of iodinated xanthenes in high purity includes a cyclization step followed by an iodination step. No extraction, chromatographic or solvent concentration steps are required, and the intermediate as well as final compounds are isolated via filtration or similar means. The process requires a single organic solvent, and the steps are completed at temperatures below 100° C. The exclusion of chloride ions, of chloride free-radicals, hypochlorite ions, or hypochlorous acid as reagents or from reagents that may generate these species in situ in the presence of oxidants, prevents undesirable impurity formation. Several new compounds have been conceived and isolated using these methods. These new compounds are also formed into new medicaments. | 10-17-2013 |
20140343296 | Process for the Synthesis of 4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo-3H-spiro[isoben- zofuran-1,9'-xanthen]-3-one (Rose Bengal) and Related Xanthenes - A new process for the manufacture of iodinated xanthenes in high purity includes a cyclization step followed by an iodination step. No extraction, chromatographic or solvent concentration steps are required, and the intermediate as well as final compounds are isolated via filtration or similar means. The process requires a single organic solvent, and the steps are completed at temperatures below 100° C. The exclusion of chloride ions, of chloride free-radicals, hypochlorite ions, or hypochlorous acid as reagents or from reagents that may generate these species in situ in the presence of oxidants, prevents undesirable impurity formation. Several new compounds have been conceived and isolated using these methods. These new compounds are also formed into new medicaments. | 11-20-2014 |
Timothy C. Scott, Knoxville, TN US
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20080207746 | Intracorporeal medicaments for photodynamic treatment of disease - New intracorporeal photodynamic medicaments and certain medical uses and methods for use of such photodynamic medicaments for treatment of disease in human or animal tissue are described, wherein a primary active component of such medicaments is a halogenated xanthene or halogenated xanthene derivative. In preferred embodiments, such medicaments are used for treatment of a variety of conditions affecting the skin and related organs, the mouth and digestive tract and related organs, the urinary and reproductive tracts and related organs, the respiratory tract and related organs, the circulatory system and related organs, the head and neck, the endocrine and lymphoreticular systems and related organs, various other tissues, such as connective tissues and various tissue surfaces exposed during surgery, as well as various tissues exhibiting microbial or parasitic infection. In another preferred embodiment, such medicaments are produced in various formulations including liquid, semisolid, solid or aerosol delivery vehicles. | 08-28-2008 |
20080311035 | Diagnostic Agents For Positron Emission Imaging Using Radiolabeled Halogenated Xanthenes - New diagnostic agents for positron emission tomography (PET) and methods for use of such agents for imaging of human or animal tissue are described, wherein a primary active component of such agents is a radiolabeled halogenated xanthene or halogenated xanthene derivative. Preferably, the radiolabeled halogenated xanthene is radiolabeled Rose Bengal or a functional derivative of Rose Bengal. | 12-18-2008 |
20090117199 | Method of treatment of cancer - A method for the treatment of cancer, particularly a metastatic melanoma or a neoplastic lesion, the method comprising intralesional administration of a hydrophilic vehicle comprising 4,5,6,7-Tetrachloro-2′,4′,5′,7′-tetraiodofluorescein, or a physiologically acceptable salt thereof, at a concentration of about 0.1 w/v % up to about 20 w/v % and an electrolyte comprising at least one cation selected from the group consisting of sodium, potassium, calcium and magnesium and at least one anion selected from the group consisting of chlorine, a phosphate and a nitrate, wherein the electrolyte is at a concentration of between about 0.1 w/v % and about 2 w/v % and the pH of the solution between about 4 to about 10. | 05-07-2009 |
20100076246 | Intracorporeal Medicaments for High Energy Phototherapeutic Treatment of Disease - New intracorporeal radiodense medicaments and certain medical uses and methods for use of such high energy phototherapeutic medicaments for treatment of human or animal tissue are described, wherein a primary active component of such medicaments is a halogenated xanthene or halogenated xanthene derivative. The halogenated xanthenes constitute a family of potent radiosensitizers that become photoactivated upon irradiation of the treatment site with ionizing radiation. In embodiments of the present invention, such medicaments are used for treatment of a variety of conditions affecting the skin and related organs, the mouth and digestive tract and related organs, the urinary and reproductive tracts and related organs, the respiratory tract and related organs, the circulatory system and related organs, the head and neck, the endocrine and lymphoreticular systems and related organs, various other tissues, such as connective tissues and various tissue surfaces exposed during surgery, as well as various tissues exhibiting microbial or parasitic infection. In another embodiment, such medicaments are produced in various formulations including liquid, semisolid, solid or aerosol delivery vehicles. | 03-25-2010 |
20110097280 | Intracorporeal Medicaments for Photodynamic Treatment of Disease - New intracorporeal photodynamic medicaments and certain medical uses and methods for use of such photodynamic medicaments for treatment of disease in human or animal tissue are described, wherein a primary active component of such medicaments is a halogenated xanthene or halogenated xanthene derivative. In preferred embodiments, such medicaments are used for treatment of a variety of conditions affecting the skin and related organs, the mouth and digestive tract and related organs, the urinary and reproductive tracts and related organs, the respiratory tract and related organs, the circulatory system and related organs, the head and neck, the endocrine and lymphoreticular systems and related organs, various other tissues, such as connective tissues and various tissue surfaces exposed during surgery, as well as various tissues exhibiting microbial or parasitic infection. In another preferred embodiment, such medicaments are produced in various formulations including liquid, semisolid, solid or aerosol delivery vehicles. | 04-28-2011 |
Timothy D. Scott, Greenbrier, TN US
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20090260614 | GRATES WITH HEAT SHIELD - In accordance with one aspect of the present invention, a cooking apparatus is provided. The cooking apparatus comprises a cooking surface, at least one grate, and a guard. The cooking surface includes at least one heat source and a control panel. The at least one grate is provided over a portion of the cooking surface. The guard is coupled to the at least one grate. The guard includes a first side and a second side. The first side of the guard is configured to deflect heat radiating from the at least one heat source. The second side of the guard corresponds with a sidewall of the cooking surface to form a channel between the guard and the sidewall. The channel is configured to create a thermal barrier between the at least one heat source and the control panel. | 10-22-2009 |
Toby Scott, Lebanon, TN US
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20100089331 | Livestock feeder with breakaway capability - A livestock feeder is provided wherein the seams of the feeder are detachable/re-attachable so as to break away from the livestock in case of entanglement. The break away feature may be applied to various configurations of livestock feeders. The breakaway feature is provided so as to avoid injury to the livestock and also make the livestock feeders easier to clean. Seam attachment means include, but are not limited to, hook and loop fasteners, adhesives, zippers, snaps or buttons. | 04-15-2010 |
Wallace Penn Scott, Clarksville, TN US
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20150278487 | SECURITY SCHEME FOR AUTHENTICATING DIGITAL ENTITIES AND AGGREGATE OBJECT ORIGINS - Systems and methods use an origin pattern to verify the authenticity of a collection of items or an entity offering items for sale. Example methods include receiving identifiers for items in a collection, determining the requesting entity is authorized to include the items in the collection, generating an origin pattern based on a hash of a private identifier for the requesting entity and a collection identifier, and providing the origin pattern for placement of packaging for the collection. Another example method includes generating a first digital identity origin pattern that is provided for display, receiving a verification request with a second digital identity origin pattern, and verifying that the verification requestor generated the first digital identity origin pattern, a fingerprint component of the first digital identity origin pattern matches a fingerprint component of the second digital identity origin pattern, and the verification request falls within a verification window. | 10-01-2015 |
20150278598 | SECURITY SCHEME FOR AUTHENTICATING OBJECT ORIGINS - Systems and methods use an origin pattern to verify the authenticity of a host object. The origin pattern includes a text-based serial number and a computer-graphics based surface-texture component. The serial number includes a public manufacturer identifier and an object identifier sequence that is based on a hash of a private manufacturer identifier and a private object identifier. The surface-texture component includes a two dimensional texture mapped onto a three dimensional surface, the generation of the surface being based on the hash. In response to an authentication request for an origin pair, the system may verify the serial number component exists in a data store and generate a challenge surface-texture component based on data in the data store. If the challenge surface-texture component matches, the system may use a time-location stamp to determine an authenticity probability and provide an indication of authenticity in response to the verification request. | 10-01-2015 |