Schwartz, CT
Abraham D. Schwartz, New Haven, CT US
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20090000125 | GROOMING TOOL - A grooming tool is provided that includes a safety razor assembly adjoined to a hair trimmer assembly. Both assemblies include a housing. The housings may be separable or may be integrally formed. The trimmer assembly includes a motor operably connected to a moving toothed blade. A second toothed blade is removably mounted to the housing of the trimmer. One end of the leaf spring is disposed in a suitably sized recess of the trimmer housing and the opposed second end bears against a driver of the moving blade to maintain sliding contact between the toothed portions of the two blades during operation. When a user removes the second toothed blade, the moving blade may be separately removed while the leaf spring is retained in its recess. Both housings have a width less than 25 mm and the grooming tool is ergonomically familiar to a typical safety razor user. | 01-01-2009 |
Brian Schwartz, Woodbridge, CT US
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20160067260 | Compositions and Methods for Treating Proliferation Disorders - The present invention relates to methods of treating cell proliferative disorders, such as cancer or Proteus syndrome, by utilizing 3-(3-(4-(1-aminocyclobutyl)phenyl)-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl)pyridin-2-amine or 3-(3-(4-(1-aminocyclobutyl)phenyl)-5-(3-morpholinophenyl)-3H-imidazo[4,5-b]pyridin-2-yl)pyridin-2-amine or N-(1-(3-(3-(4-(1-aminocyclobutyl)phenyl)-2-(2-aminopyridin-3-yl)-3H-imidazo[4,5-b]pyridin-5-yl)phenyl)piperidin-4-yl)-N-methylacetamide. The methods of the present invention can also relate to methods of treating cell proliferative disorders, such as cancer or Proteus syndrome, by utilizing the above compounds in combination with ((R)-6-(2-fluorophenyl)-N-(3-(2-((2-methoxyethyl)amino)ethyl)phenyl)-5,6-dihydrobenzo[h]quinazolin-2-amine). | 03-10-2016 |
Brian Eric Schwartz, Woodbridge, CT US
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20080241274 | Indibulin therapy - The invention provides combination therapy, wherein one or more other therapeutic agents are administered with indibulin or a pharmaceutically acceptable salt thereof and the combination is synergistic. Another aspect of the invention relates to the treatment of cancer with indibulin as a single agent. Another aspect of the invention relates to dosing regimen for administration of oral dosage forms of indibulin. | 10-02-2008 |
20110269697 | ORGANOARSENIC COMPOUNDS AND METHODS FOR THE TREATMENT OF CANCER - A method for treating a lymphoma selected from non-Hodgkin's and Hodgkin's lymphoma comprising administering an organoarsenic compound having a structure of the formula (I) wherein X is S or Se and R | 11-03-2011 |
20130084345 | INDIBULIN THERAPY - The invention provides combination therapy, wherein one or more other therapeutic agents are administered with indibulin or a pharmaceutically acceptable salt thereof and the combination is synergistic. Another aspect of the invention relates to the treatment of cancer with indibulin as a single agent. Another aspect of the invention relates to dosing regimen for administration of oral dosage forms of indibulin. | 04-04-2013 |
20140193519 | INDIBULIN THERAPY - The invention provides combination therapy, wherein one or more other therapeutic agents are administered with indibulin or a pharmaceutically acceptable salt thereof and the combination is synergistic. Another aspect of the invention relates to the treatment of cancer with indibulin as a single agent. Another aspect of the invention relates to dosing regimen for administration of oral dosage forms of indibulin. | 07-10-2014 |
20150231107 | ORGANOARSENIC COMPOUNDS AND METHODS FOR THE TREATMENT OF CANCER - A method for treating a lymphoma selected from non-Hodgkin's and Hodgkin's lymphoma comprising administering an organoarsenic compound having a structure of the formula (I) wherein X is S or Se and R | 08-20-2015 |
Brian J. Schwartz, West Hartford, CT US
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20090075564 | SUPERABRASIVE TOOL AND MACHINING METHODS - A tool for use in an abrasive machining process has a body extending along a central longitudinal axis from a first end to a tip end. An abrasive material is located on the tip end. The body has a tip end protuberance. An abrasive material is located on the protuberance. A body lateral surface has, over a radial span of at least 20% of a radius of the protuberance, a continuously concave longitudinal profile diverging tipward. | 03-19-2009 |
20090094831 | METHOD FOR RESTORING AIRFOIL CONTOUR ON INTEGRALLY BLADED ROTORS - An integrally bladed rotor includes a central hub and a plurality of airfoils or blades. The blades are repaired by rebuilding their surfaces beyond the original shape, such as by adding weld material. The contour of the blade is then returned to the desired shape using superabrasive quills. | 04-16-2009 |
Evan I. Schwartz, Ridgefield, CT US
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20090012878 | Apparatus, Systems and Methods for Facilitating Commerce - According to one or more embodiments, apparatus, systems and methods are provided for facilitating commerce. In some embodiments, an apparatus (e.g., a central computer) facilitates posting of an item for sale by receiving a digital image of an item for sale, receiving an audio description (e.g., included in an audio file) of the item, and providing an indication of the description to at least one potential buyer. In one embodiment, the digital image and the audio description are received from a mobile phone. | 01-08-2009 |
20100244380 | BLACKJACK TEAM PLAY - A blackjack game is modified to include an auxiliary wager that is based on whether any of the hands at the blackjack table will beat the dealer's hand. A player may thus place an auxiliary wager on whether his hand or a second player's hand will beat the dealer. Alternate expressions of the concept allow variations in which player's hand or how many hands may be included in the comparison. | 09-30-2010 |
Martin A. Schwartz, Milford, CT US
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20160067314 | COMPOSITIONS AND METHODS FOR INHIBITING CHEMORESISTANCE IN CANCER AND IMPROVING RESPONSE TO THERAPY - Metastatic melanomas are highly resistant to radiation and chemotherapy from the earliest stages, which is a major factor in poor clinical outcomes. Activated leukocyte adhesion molecule (ALCAM)/CD166 was the gene that showed the highest correlation with detachment-induced chemoresistance. SiRNA-mediated depletion or antibody blocking of ALCAM specifically inhibited the increase in chemoresistance after detachment. This antibody also improved chemotherapeutic responses in a mouse xenograft model of human melanoma. Previous studies identified ALCAM as a marker for tumor aggressiveness and poor prognosis, and as a marker for “stemness”. Targeting ALCAM may therefore represent a novel approach for treatment of otherwise intractable melanomas. It was also found that stimulating integrin signaling enhanced chemosensitivity of melanoma to chemotherapeutic agents. The present invention provides a novel multimeric peptide construct comprising fibronectin fragments useful for stimulating integrin signaling and for enhancing chemosensitivity of melanomas. | 03-10-2016 |
Robert Schwartz, West Granby, CT US
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20080270323 | System, Method, and Computer Program Product for Providing Stabilized Annuity Payments and Control of Investments in a Variable Annuity Patent Application - A system, method, and computer program product for providing stabilized annuity payments and control of investments in a variable annuity, the system comprising a processor, a memory, and a computer program stored in the memory. The computer program allocates the short and long term risks associated with an investment to the potential beneficiaries of the annuitant by controlling the allocation of assets between two investment pools. The annuitant pool is the pool on which annuity payments are based and the beneficiary pool contains assets that are provided to the beneficiaries upon the death of the annuitant. The beneficiary pool is used as a cushion to isolate the contents of the annuitant pool from fluctuations in value. The beneficiary pool is initially funded with sufficient assets to minimize the likelihood of its depletion under fairly conservative estimates of market conditions. If the underlying investments perform poorly, assets from the beneficiary pool are reallocated to the annuity pool in order to maintain the existing annuity payment. Thus, for as long as the beneficiary pool is not depleted, the annuity payment is stabilized and will not decrease. If the underlying investments perform favorably, increasing in value, excess amounts above a set trigger level amount will be periodically transferred to the annuitant pool. As these gains are transferred to the annuity pool, the annuity payment amounts will be increased accordingly. | 10-30-2008 |
20100185560 | System, Method, and Computer Program Product for Allocating Assets Among a Plurality of Investments to Guarantee a Predetermined Value at the End of a Predetermined Period - A system, method, and computer program product for allocating assets among a plurality of investments to guarantee a predetermined value at the end of a predetermined time period. A computer program controls the allocation of assets in the investment vehicle, which allows the investor to initially invest one hundred percent of the initial deposit in non-secure, high risk investments. At the end of the each trading day, the computer program determines if assets should be reallocated from the non-secure investments to the secure investments, from the secure investments to the non-secure investments, or if no reallocation is necessary. | 07-22-2010 |
20120284205 | SYSTEM, METHOD, AND COMPUTER PROGRAM PRODUCT FOR ALLOCATING ASSETS AMONG A PLURALITY OF INVESTMENTS TO GUARANTEE A PREDETERMINED VALUE AT THE END OF A PREDETERMINED PERIOD - A system, method, and computer program product for allocating assets among a plurality of investments to guarantee a predetermined value at the end of a predetermined time period. A computer program controls the allocation of assets in the investment vehicle, which allows the investor to initially invest one hundred percent of the initial deposit in non-secure, high risk investments. At the end of the each trading day, the computer program determines if assets should be reallocated from the non-secure investments to the secure investments, from the secure investments to the non-secure investments, or if no reallocation is necessary. | 11-08-2012 |
Robert J. Schwartz, West Granby, CT US
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20100332365 | Financial Instrument Providing a Guaranteed Growth Rate and a Guarantee of Lifetime Payments - A method for providing a financial instrument includes determining an initial account balance associated with a financial instrument based upon an initial deposit amount, wherein the financial instrument includes an account with an account balance that changes over time. The method further includes establishing a first guarantee of a protected value, the protected value including at least an amount based upon the initial account balance growing at a minimum growth rate for a defined period of time or until one or more defined events occur, whichever is sooner; and establishing a second guarantee that a beneficiary may periodically receive a transfer of an amount of money for the life of a designated party, wherein the amount comprises a percentage of the protected value at the time of a particular event, provided that the amount may vary based upon withdrawals from the account in excess of a first particular limit. | 12-30-2010 |
20110145169 | System and Method for Providing a Financial Instrument Utilizing a Liability Ratio - One embodiment of the invention is a method for providing a financial instrument including determining a current account balance for a financial account, calculating a liability ratio for the financial account, and determining whether to transfer at least a portion of the account balance from a variable sub-account to a low-risk sub-account based on the liability ratio. | 06-16-2011 |