Patent application number | Description | Published |
20090257555 | X-Ray Inspection Trailer - An inspection system, and inspection methods, based upon an imaging enclosure characterized by an enclosing body. A source of penetrating radiation and a detector module are concealed entirely within the body of a conveyance such as a trailer. A characterizing value or an image is formed with respect to an inspected object that is disposed entirely outside the conveyance and the characterizing value or image is made available to a remotely disposed operator. Additional detectors may be disposed distally to the inspected object and may detect transmitted, or forward-scattered, penetrating radiation. | 10-15-2009 |
20130202089 | Convertible Scan Panel for X-Ray Inspection - An x-ray inspection system using backscatter of an x-ray beam emitted through a scan panel contiguous with, but of a material distinct from, an enclosure that contains an x-ray source by which the x-ray beam is generated. The scan panel is contoured in such a manner as to be visibly blended with a shape characterizing the enclosure. In some embodiments, the beam traverses multiple scan panels, where one or more of the scan panels may be selected for beam filtration properties. The scan panel may be disposed interior to a sliding door, and may be structured to serve as a scatter shield. | 08-08-2013 |
20130208857 | X-Ray Inspection using Wavelength-Shifting Fiber-Coupled Scintillation Detectors - A detector and methods for inspecting material on the basis of scintillator coupled by wavelength-shifting optical fiber to one or more photo-detectors, with a temporal integration of the photo-detector signal. An unpixelated volume of scintillation medium converts energy of incident penetrating radiation into scintillation light which is extracted from a scintillation light extraction region by a plurality of optical waveguides. This geometry provides for efficient and compact detectors, enabling hitherto unattainable geometries for backscatter detection and for energy discrimination of incident radiation. Additional energy-resolving transmission configurations are enabled as are skew- and misalignment compensation. | 08-15-2013 |
Patent application number | Description | Published |
20090116617 | Multiple Image Collection and Synthesis for Personnel Screening - An apparatus and method for inspecting personnel or their effects. A first and second carriage each carries a source for producing a beam of penetrating radiation incident on a subject. A positioner provides for synchronized relative motion of each carriage vis-à-vis the subject in a direction having a vertical component. A detector receives radiation produced by at least one of the sources after the radiation interacts with the subject. | 05-07-2009 |
20090268871 | X-Ray Inspection with Contemporaneous and Proximal Transmission and Backscatter Imaging - An X-ray imaging inspection system for bags and packages. Transmission imaging is performed using a fan beam and a segmented detector, while scatter imaging is performed with a scanned pencil beam, with both beams active simultaneously. Cross-talk between the beams is mitigated by a combination of shielding, scatter detector design, positioning and orientation, and image processing. Image processing subtracts the measured radiation scattered from the transmission beam into the scatter detectors, reducing cross-talk | 10-29-2009 |
20100104069 | Multiple Image Collection and Synthesis for Personnel Screening - An apparatus and method for inspecting personnel or their effects. A first and second carriage each carries a source for producing a beam of penetrating radiation incident on a subject. A positioner provides for synchronized relative motion of each carriage vis-á-vis the subject in a direction having a vertical component. A detector receives radiation produced by at least one of the sources after the radiation interacts with the subject. | 04-29-2010 |
20110017917 | Multiple Image Collection and Synthesis for Personnel Screening - An apparatus and method for inspecting personnel or their effects. A first and second carriage each carries a source for producing a beam of penetrating radiation incident on a given subject. A positioner provides for relative motion of each beam vis-à-vis the subject in a motion, the vertical component of which is one-way. A detector receives radiation produced by at least one of the sources after the radiation interacts with the subject. | 01-27-2011 |
20110164726 | Multiple Image Collection and Synthesis for Personnel Screening - An apparatus and method for inspecting personnel or their effects. A first and second carriage each carries a source for producing a beam of penetrating radiation incident on a given subject. A positioner provides for relative motion of each beam vis-à-vis the subject in a motion, the vertical component of which is one-way. A detector receives radiation produced by at least one of the sources after the radiation interacts with the subject. | 07-07-2011 |
20120106714 | Versatile X-Ray Beam Scanner - Apparatus for interrupting and/or scanning a beam of penetrating radiation, such as for purposes of inspecting contents of a container. A source, such as an x-ray tube, generates a fan beam of radiation effectively emanating from a source axis, with the width of the fan beam collimated by a width collimator, such as a clamshell collimator. An angular collimator, stationary during the course of scanning, limits the extent of the scan, and a multi-aperture unit, such as a hoop, or a nested pair of hoops, is rotated about a central axis, and structured in such a manner that beam flux incident on a target is conserved for different fields of view of the beam on the target. The central axis of hoop rotation need not coincide with the source axis. | 05-03-2012 |
20120263276 | Backscatter System with Variable Size of Detector Array - A variable-geometry backscatter inspection system has a radiation detector array including one or more backscatter radiation detectors. The position of a second backscatter radiation detector is variable with respect to the position of a first backscatter radiation detector, so that the size of the detector array may be varied by moving the second radiation detector into or out of a predefined alignment with the first radiation detector. The system may include a movable base, and at least one of the detectors is movable with respect to the base. Methods of inspecting an object include forming a detector array by moving a second radiation detector into a predefined alignment with a first radiation detector, illuminating the object with a pencil beam of penetrating radiation, and detecting backscattered radiation with the detector array. | 10-18-2012 |
20120269319 | Versatile X-Ray Beam Scanner - Apparatus for interrupting and/or scanning a beam of penetrating radiation, such as for purposes of inspecting contents of a container. A source, such as an x-ray tube, generates a fan beam of radiation effectively emanating from a source axis, with the width of the fan beam collimated by a width collimator, such as a clamshell collimator. An angular collimator, stationary during the course of scanning, limits the extent of the scan, and a multi-aperture unit, such as a hoop, or a nested pair of hoops, is rotated about a central axis, and structured in such a manner that the total beam fluence incident on a target is conserved for different fields of view of the beam on the target. The central axis of hoop rotation need not coincide with the source axis. | 10-25-2012 |
20130003936 | Adjustable-Jaw Collimator - An adjustable collimator for shaping a beam of particles, such as for purposes of inspecting contents of a container. The adjustable collimator has an obscuring element substantially opaque to passage of the particles in a propagation direction that is radial with respect to the axis of rotation of a ring of apertures. A gap in the obscuring element may be characterized by a length taken along a long dimension and a jaw spacing taken along narrow dimension, and at least one of the length of the gap and the jaw spacing is subject to adjustment, either manual or automatic. The adjustable collimator may be disposed either inside or outside the ring of apertures, and, in some embodiments, the jaw spacing may be a function of distance along the long dimension relative to an edge of the gap. | 01-03-2013 |
20130101090 | Methods to Perform Backscatter Inspection of Complex Targets in Confined Spaces - Embodiments of backscatter inspection systems include features to enable inspection of irregular surfaces, tight spacer, and other hard-to-reach places. Some embodiments include arms that maneuver a scan head with at least three degrees of freedom, and some embodiments include arms that maneuver a scan head with at least seven degrees of freedom. Some embodiments include proximity detectors on a scan head or base, detect contact with an object being inspected, and to slow or stop the motion of the system accordingly. Some compact embodiments scan the interior of an object from within, and include a rotating, low-energy source of penetrating radiation, and at least one backscatter detector, which may be stationary, or may rotate with the source. | 04-25-2013 |
20140233707 | Versatile Beam Scanner with Fan Beam - A versatile beam scanner for generating a far-field scanned pencil beam, and, alternatively, a far-field pencil beam. An angle selector limits the angular extent of an inner fan beam emitted by a source of penetrating radiation. The source and angle selector may be translated, along a direction parallel to a central axis of a multi-aperture unit, in such a manner as to generate a scanned far-field pencil beam, when rings of apertures are interposed between the source and an inspected target, or, alternatively, a far-field fan beam, when no ring of apertures is interposed. | 08-21-2014 |
20150378048 | Inspection of Baggage from within a Conveyance - Methods and apparatus for parcel inspection with x-rays. A source of penetrating radiation contained entirely within an enclosing body of a conveyance generates a beam of penetrating radiation incident upon a parcel while the parcel is disposed externally to the enclosing body. A detector generates an inspection signal based on detection of penetrating radiation after interaction with contents of the parcel. A conveyor positions the parcel with respect to the beam of penetrating radiation, while a processor ascertains a specified characteristic of the parcel based on the inspection signal. | 12-31-2015 |
Patent application number | Description | Published |
20110142324 | METHOD OF RECONSTITUTING CELLULAR SPECTRA USEFUL FOR DETECTING CELLULAR DISORDERS - Embodiments of the present disclosure provides improved methods for determining the presence of abnormalities in exfoliated cells. In one embodiment, the present disclosure provides methods for reconstructing cellular spectrum of a cell sample by creating a spectral map of the cellular sample, generating a binary mask of the spectral map, removing edge artifacts from each cell, and co-adding spectral data of each pixel corresponding to the cell to reconstruct the spectrum of each cell. | 06-16-2011 |
20140205172 | METHOD OF RECONSTITUTING CELLULAR SPECTRA USEFUL FOR DETECTING CELLULAR DISORDERS - Embodiments of the present disclosure provides improved methods for determining the presence of abnormalities in exfoliated cells. In one embodiment, the present disclosure provides methods for reconstructing cellular spectrum of a cell sample by creating a spectral map of the cellular sample, generating a binary mask of the spectral map, removing edge artifacts from each cell, and co-adding spectral data of each pixel corresponding to the cell to reconstruct the spectrum of each cell. | 07-24-2014 |
20150213601 | Method of Reconstituting Cellular Spectra Useful for Detecting Cellular Disorders - Embodiments of the present disclosure provides improved methods for determining the presence of abnormalities in exfoliated cells. In one embodiment, the present disclosure provides methods for reconstructing cellular spectrum of a cell sample by creating a spectral map of the cellular sample, generating a binary mask of the spectral map, removing edge artifacts from each cell, and co-adding spectral data of each pixel corresponding to the cell to reconstruct the spectrum of each cell. | 07-30-2015 |
Patent application number | Description | Published |
20130243131 | REAL-TIME I/Q IMBALANCE CORRECTION FOR WIDE-BAND RF RECEIVER - A receiver apparatus models and corrects the frequency-dependent and the frequency-independent mismatches between I and Q paths jointly by polynomial estimations. The receiver apparatus may sample digitized I and Q path signals. The sampled data point may be modeled in equations with real and imaginary components. The sampled discrete time-domain data may be converted to frequency-domain data. Multiple statistics values based on the frequency-domain data may be computed. Coefficients for the polynomial equations may be estimated based on the computed statistic values. The channel mismatches may be estimated from the polynomial equations and used to compensate the mismatch either on the I path or the Q path. | 09-19-2013 |
20140270001 | QUADRATURE ERROR DETECTION AND CORRECTION - In an example, there is disclosed a system and method for detecting and correcting error in a quadrature receiver (QR). The QR may include a receiver channel operable to divide a received RF signal into I and Q channels. The receiver channel may include error sources, such as (in sequence) pre-demodulation (PD) error, LO mixer error, and baseband (BB) error. Test tones may be driven on the receiver channel at a plurality of test frequencies, and a quadrature error corrector may be provided to detect error from each source. Upon receiving an RF signal, the quadrature error corrector may apply correction coefficients to correct each source of error in reverse sequence (BB, LO, PD). | 09-18-2014 |
20140270002 | SYSTEM AND METHOD QUADRATURE ERROR DETECTION AND CORRECTION - In an example, there is disclosed a system and method for detecting and correcting error in a quadrature receiver (QR). The QR may include a receiver channel operable to divide a received RF signal into I and Q channels. The receiver channel may include error sources, such as (in sequence) pre-demodulation (PD) error, LO mixer error, and baseband (BB) error. Test tones may be driven on the receiver channel at a plurality of test frequencies, and a quadrature error corrector may be provided to detect error from each source. Upon receiving an RF signal, the quadrature error corrector may apply correction coefficients to correct each source of error in reverse sequence (BB, LO, PD). | 09-18-2014 |
20140273902 | QUADRATURE ERROR CORRECTION USING POLYNOMINAL MODELS IN TONE CALIBRATION - One example embodiment provides a system, apparatus, and method for using polynomial models in tone calibration for quadrature error correction in I/Q receivers. In one example embodiment, method for calibrating an I/Q receiver is provided and includes receiving a first mismatch parameter indicating a mismatch between I and Q channels of the I/Q receiver; and estimating a second mismatch parameter from the first mismatch parameter using a polynomial model. | 09-18-2014 |
20150236739 | APPARATUS AND METHODS FOR WIDE BANDWIDTH ANALOG-TO-DIGITAL CONVERSION OF QUADRATURE RECEIVE SIGNALS - Apparatus and methods for analog-to-digital conversion of quadrature receive signals are provided herein. In certain implementations, a transceiver system includes at least a first pair of analog-to-digital converters (ADCs) associated with a first quadrature receiver channel and a second pair of ADCs associated with a second quadrature receiver channel. The first and second pairs of ADCs can provide analog-to-digital conversion of the same receive signal, but can have different noise profiles relative to one another, such as a low pass noise profile and a band pass noise profile. The transceiver system can further include a reconstruction filter for combining the outputs of at least the first and second pairs of ADCs to generate output signals associated with a lower overall noise profile relative to that of either pair of ADCs alone. | 08-20-2015 |
Patent application number | Description | Published |
20120093914 | IMPLANTABLE LIPOSOME EMBEDDED MATRIX COMPOSITION, USES THEREOF, AND POLYCAPROLACTONE PARTICLES AS SCAFFOLDS FOR TISSUE REGENERATION - In various embodiments, the present invention describes materials and methods for the local reprogramming of cells in a location where the treatment is applied. The invention can be used to replace lost cells or to restore function to tissue damaged due to disease, injury or genetic defect. In various embodiments, the treatment includes a semisolid hydrogel embedded with liposomes. The liposomes can contain an effector molecule or molecules. When phagocytic cells such as monocytes infiltrate the hydrogel, they encounter the liposomes and incorporate the liposomes carrying the effector molecules into the cells. In some embodiments, the effector molecules can be genetic material encoding the expression of specific proteins such as transcription factors, the expression of which can initiate the reprogramming of the cells. In other embodiments, the effector molecules can induce angiogenesis. In other embodiments, the effector molecules are tumor antigens. The matrix can contain other effector molecules designed to attract specific cells to the matrix. The cells can be released from the matrix as the matrix degrades or by active migration from the matrix. The cells can also remain in the matrix and secret molecules such as proteins and hormones that will diffuse through the matrix material to the surrounding tissue. | 04-19-2012 |
20120323152 | COMPRESSION DEVICE - Described are improved apparatus and devices for intermittently and sequentially compressing a body site and methods for using said apparatus and devices, especially for site specific treatment to achieve a desired temperature of the underlying tissue. The apparatus includes a first segment cooperative with a fluid chamber, the fluid chamber adapted for inflation by fluid; and a second segment cooperative with the first segment, the second segment housing a temperature sensitive material, wherein the temperature sensitive material is uniquely compartmentalized in the second segment. | 12-20-2012 |
20140316314 | COMPRESSION DEVICE - Described are improved apparatus and devices for intermittently and sequentially compressing a body site and methods for using said apparatus and devices, especially for site specific treatment to achieve a desired temperature of the underlying tissue. The apparatus includes a first segment cooperative with a fluid chamber, the fluid chamber adapted for inflation by fluid; and a second segment cooperative with the first segment, the second segment housing a temperature sensitive material, wherein the temperature sensitive material is uniquely compartmentalized in the second segment. | 10-23-2014 |
20150050332 | IMPLANTABLE LIPOSOME EMBEDDED MATRIX COMPOSITION, USES THEREOF, AND POLYCAPROLACTONE PARTICLES AS SCAFFOLDS FOR TISSUE REGENERATION - In various embodiments, the present invention describes materials and methods for the local reprogramming of cells in a location where the treatment is applied. The invention can be used to replace lost cells or to restore function to tissue damaged due to disease, injury or genetic defect. In various embodiments, the treatment includes a semisolid hydrogel embedded with liposomes. The liposomes can contain an effector molecule or molecules. When phagocytic cells such as monocytes infiltrate the hydrogel, they encounter the liposomes and incorporate the liposomes carrying the effector molecules into the cells. In some embodiments, the effector molecules can be genetic material encoding the expression of specific proteins such as transcription factors, the expression of which can initiate the reprogramming of the cells. In other embodiments, the effector molecules can induce angiogenesis. In other embodiments, the effector molecules are tumor antigens. The matrix can contain other effector molecules designed to attract specific cells to the matrix. The cells can be released from the matrix as the matrix degrades or by active migration from the matrix. The cells can also remain in the matrix and secret molecules such as proteins and hormones that will diffuse through the matrix material to the surrounding tissue. | 02-19-2015 |
Patent application number | Description | Published |
20110038937 | Methods for delivering siRNA via Ionthophoresis - Disclosed herein are formulations of siRNA suitable for delivery by ocular iontophoresis, devices for iontophoretic delivery of siRNA and methods of use thereof. | 02-17-2011 |
20110301526 | SYSTEM AND METHOD FOR OCULAR IONTOPHORESIS WITH BUFFERING - Compositions, devices, methods of manufacture, and methods of delivery of a therapeutic substance across a surface of an eyeball via iontophoresis including a therapeutic media reservoir and a buffer system within an iontophoretic chamber. When energized, an electrode provides an electromotive force that transfers a dosage of the therapeutic substance from the iontophoretic chamber across the surface of the eyeball. The buffering system includes a buffer media and at least one buffer element, or agent that regulates pH during iontophoretic transfer of the therapeutic substance. The buffer media includes at least one of a foam, a gel (solid or liquid), a membrane, and a plurality of multiparticulates. The buffer media can be included within the iontophoretic chamber, together with the therapeutic media reservoir, in various arrangements including one or more layers and one or more concentric cylinders. | 12-08-2011 |
20160120696 | SYSTEN AND METHOD FOR OCULAR IONTOPHORESIS WITH BUFFERING - Compositions, devices, method of manufacture, and methods of delivery of a therapeutic substance across a surface of an eyeball via iontophoresis including a therapeutic media reservoir and a buffer system within an iontophoretic chamber. When energized, an electrode provides and electromotive force that transfers a dosage of the therapeutic substance from the iontophoretic chamber across the surface of the eyeball. The buffering system includes a buffer media and at least on buffer elementt, or agent that regulates pH during iontophoretic transfer of the therapeutic substance. The buffer media includes at least one of a foam, a gel (solid or liquid), a membrane, and a plurality of multi-particulates. The buffer media can be included within the iontophoretic chamber, together with the therapeutic media reservoir, in various arrangements including on or more layers and one or more concentric cylinders. | 05-05-2016 |