Patent application number | Description | Published |
20080260366 | IMAGE STABILIZATION WITH ADAPTIVE SHUTTER CONTROL - An apparatus to facilitate image stabilization with adaptive shutter control is described. An embodiment of the apparatus includes an image sensor, a movement detector, and a shutter controller. The movement detector is coupled to the image sensor. The shutter controller is coupled to the movement detector. The image sensor is configured to obtain image data. The movement detector is configured to obtain movement measurement information during a shutter period having a predetermined duration. The shutter controller is configured to adjust the shutter period of a shutter based on the movement measurement information. The shutter controls the time the image sensor is responsive to light incident on the image sensor. Embodiments of the apparatus provide a smaller and less costly implementation for image stabilization. | 10-23-2008 |
20090040318 | IMAGE STABILIZATION WITH USER FEEDBACK - An apparatus to facilitate image stabilization with user feedback is described. An embodiment of the apparatus includes an image sensor, a movement detector, and a digital processor. The image sensor acquires an image of a scene over an exposure period. The movement detector is coupled to the image sensor. The movement detector computes a movement measurement of the image sensor during the exposure period. The digital processor is coupled to the movement detector. The digital processor provides feedback to a user during the exposure period. The feedback is based on the movement measurement. Embodiments of the apparatus provide a simpler and less costly implementation for image stabilization. | 02-12-2009 |
20140039318 | Automated detection of suspected abnormalities in ultrasound breast images - A method and system for processing and displaying breast ultrasound information is described. A 2D feature weighted volumetric coronal image as a “guide” or “road map” is generated from the 3D ultrasound data volume to represent the 3D dataset with the goal of emphasizing abnormalities within the breast while excluding non-breast structures, particularly those external to the breast such as ribs and chest wall. | 02-06-2014 |
20140082542 | VIEWING AND CORRELATING BETWEEN BREAST ULTRASOUND AND MAMMOGRAM OR BREAST TOMOSYNTHESIS IMAGES - This specification describes a novel user interface and method for viewing mammograms together with 3D breast ultrasound images for breast cancer screening. The user identifies a region of interest, in one modality and the processing system calculates the location in the other modality. Visual aids such as icons can be used to display the calculated location in the other modality in cases where the other modality is viewed on a separate device. In cases where an integrated display device is used that displays both modalities, the visual aid can be an ROI marker on the target modality. The user interface and method for viewing has been found to greatly decrease the tedium and likelihood for errors when compared with known displaying viewing techniques. | 03-20-2014 |
20140343420 | Reduced Image Reading Time and Improved Patient Flow in Automated Breast Ultrasound Using Enchanced, Whole Breast Navigator Overview Images - A method and system acquiring, processing and displaying breast ultrasound images in a way that makes breast ultrasound screening more practical and thus more widely used, and reduces missing cancers in screening and diagnosis, using automated scanning of chestwardly compressed breasts with ultrasound. Enhanced, whole-breast navigator overview images are generated from scanning breasts with ultrasound that emphasize abnormalities in the breast while excluding obscuring influences of non-breast structures, particularly those external to the breast such as ribs and chest wall, and differentiating between likely malignant and likely benign abnormalities and otherwise enhancing the navigator overview image and other images, to thereby reduce the time to read, screen, or diagnose to practical time limits and also reduce screening or diagnostic errors. | 11-20-2014 |
20150087979 | AUTOMATED BREAST ULTRASOUND EQUIPMENT AND METHODS USING ENHANCED NAVIGATOR AIDS - A method and system acquiring, processing and displaying breast ultrasound images in a way that makes breast ultrasound screening more practical and thus more widely used, and reduces the occurrence of missing cancers in screening and diagnosis, using automated scanning of chestwardly compressed breasts with ultrasound. Enhanced, whole-breast navigator overview images are produced from scanning breasts with ultrasound that emphasize abnormalities in the breast while excluding obscuring influences of non-breast structures, particularly those external to the breast such as ribs and chest wall, and differentiating between likely malignant and likely benign abnormalities and otherwise enhancing the navigator overview image and other images, thereby reducing the time to read, screen, and/or diagnose to practical time limits and also reduce screening or diagnostic errors. | 03-26-2015 |
Patent application number | Description | Published |
20090012982 | SYSTEM AND METHOD FOR ENABLING PARALLEL ACCESS TO SERIALLY COMPRESSED FILES - The present invention is directed towards systems and methods for generating a compressed data file providing access to one or more selected portions of data contained within the data file. The file is partitioned into one or more chunks, a given chunk comprising a separate unit of data representing a subset of data from the file. The one or more chunks are compressed through use of a compression algorithm, and the one or more chunks are combined to form a compressed file. Metadata is also generated that indicates a chunk offset of a given chunk, thereby allowing direct parallel access to one or more given chunks. Similarly, legacy applications may ignore the chunk structure in the compressed file and access the file according to techniques know in the art, thereby preserving backwards compatibility with such legacy applications. | 01-08-2009 |
20120144313 | FILTERING OBJECTS IN A MULTI-TENANT ENVIRONMENT - Various techniques and procedures related to filtering objects in a virtual application within a multi-tenant system are provided. One approach involves providing a first graphical user interface element enabling indication of a first filtering criterion and a second graphical user interface element enabling indication of a second filtering criterion within the virtual application being accessed over a network from a client device. After indication of the first filtering criterion and the second filtering criterion, a filtered set of objects is identified based on the first filtering criterion and the second filtering criterion. At least a portion of the filtered set of objects may then be presented within the virtual application on a client device. | 06-07-2012 |
20120330960 | SYSTEMS AND METHODS FOR MAPPING A VALUE TO A NEW DOMAIN - Source values are mapped to new user-defined categories. The new user-defined categories are stored in a new user-defined field. In an embodiment, a user-selection of an existing field is received. Based on a data type of the existing field, a specific mapping interface is displayed. The interface guides the user through specification of the new field and categories, and identification of the source values to map to the new categories. | 12-27-2012 |
20130246951 | FILTERING OBJECTS IN A MULTI-TENANT ENVIRONMENT - Various techniques and procedures related to filtering objects in a virtual application within a multi-tenant system are provided. One approach involves providing a first graphical user interface element enabling indication of a first filtering criterion and a second graphical user interface element enabling indication of a second filtering criterion within the virtual application being accessed over a network from a client device. After indication of the first filtering criterion and the second filtering criterion, a filtered set of objects is identified based on the first filtering criterion and the second filtering criterion. At least a portion of the filtered set of objects may then be presented within the virtual application on a client device. | 09-19-2013 |
Patent application number | Description | Published |
20110214064 | SYSTEM, METHOD AND COMPUTER PROGRAM PRODUCT FOR DISPLAYING ONE OR MORE DATA SETS TO A USER - In accordance with embodiments, there are provided mechanisms and methods for displaying one or more data sets to a user. These mechanisms and methods for displaying one or more data sets to a user can enable enhanced data security, more relevant data display, reduced processing, etc. | 09-01-2011 |
20110258178 | METHODS AND SYSTEMS FOR PERFORMING CROSS STORE JOINS IN A MULTI-TENANT STORE - Methods and systems for performing cross store joins in a multi-tenant store are described. In one embodiment, such a method includes retrieving data from a multi-tenant database system having a relational data store and a non-relational data store, receiving a request specifying data to be retrieved from the multi-tenant database system, retrieving, based on the request, one or more locations of the data to be retrieved, generating a database query based on the request, in which the database query specifies a plurality of data elements to be retrieved, the plurality of data elements including one or more data elements residing within the non-relational data store and one or more other data elements residing within the relational data store, and executing the database query against the multi-tenant database system to retrieve the data. | 10-20-2011 |
20130246399 | SYSTEM, METHOD AND COMPUTER PROGRAM PRODUCT FOR DISPLAYING ONE OR MORE DATA SETS TO A USER - In accordance with embodiments, there are provided mechanisms and methods for displaying one or more data sets to a user. These mechanisms and methods for displaying one or more data sets to a user can enable enhanced data security, more relevant data display, reduced processing, etc. | 09-19-2013 |
Patent application number | Description | Published |
20080226656 | RG1 antibodies and uses thereof - The present invention relates to antibodies, and antigen-binding antibody fragments, directed against an RG1 polypeptide. The invention further relates to methods for utilizing the antibodies, and antibody fragments, for diagnostic and therapeutic applications. | 09-18-2008 |
20100081795 | RG1 ANTIBODIES AND USES THEREOF - The present invention relates to antibodies, and antigen-binding antibody fragments, directed against an RG1 polypeptide. The invention further relates to methods for utilizing the antibodies, and antibody fragments, for diagnostic and therapeutic applications. | 04-01-2010 |
20110104058 | DIMERIC MOLECULAR COMPLEXES - Dimeric molecular complexes comprising an IgE CH4 dimerization domain useful for diagnostics and therapeutics. | 05-05-2011 |
20110229476 | MONOSPECIFIC AND MULTISPECIFIC ANTIBODIES AND METHOD OF USE - This invention relates to monospecific and multispecific antibodies that may be utilized for the diagnosis and treatment of various diseases. In addition, these antibodies may be modified by protease cleavage. Protease control or regulation may be provided by a protease site located in, for example, a linker. These protease-regulated antibodies may also be utilized for the diagnosis and treatment of various diseases. | 09-22-2011 |
Patent application number | Description | Published |
20090214422 | DNA encoding a novel RG1 polypeptide - The present invention relates to novel human extracellular matrix polypeptides, designated RG1, polynucleotides encoding the polypeptides, methods for producing the polypeptides, expression vectors and genetically engineered host cells for expression of the polypeptides. The invention further relates to antibodies directed against the polypeptides and to methods for using the polynucleotides, and polypeptides, and antibodies in research, diagnosis, and therapeutic applications. | 08-27-2009 |
20090292112 | DNA encoding a novel RG1 polypeptide - The present invention relates to novel human extracellular matrix polypeptides, designated RG1, polynucleotides encoding the polypeptides, methods for producing the polypeptides, expression vectors and genetically engineered host cells for expression of the polypeptides. The invention further relates to antibodies directed against the polypeptides and to methods for using the polynucleotides, and polypeptides, and antibodies in research, diagnosis, and therapeutic applications. | 11-26-2009 |
20120142593 | Factor VIII Variants and Methods of Use - A Factor VIII fusion protein or a Factor VIII fusion heterodimer comprising Factor VIII in which an amino acid sequence of a modulator is present in the B-domain, or an amino acid sequence of a modulator replaces some or all of the amino acid sequence of the B-domain is disclosed. Nucleic acids encoding the inventive fusion proteins and fusion heterodimers are also disclosed, as are methods for producing the fusion proteins and fusion heterodimers, pharmaceutical compositions, and methods of treating deficiencies in coagulation with the inventive fusion molecules. | 06-07-2012 |
Patent application number | Description | Published |
20100223667 | APPARATUS, SYSTEM, AND METHOD FOR START-UP AUTHENTICATION - An apparatus, system, and method are disclosed for start-up authentication. A prompt module prompts for a hardware password and authentication data on a single display screen. The authentication data comprises a user password. The user password is distinct from the hardware password. A store module stores the authentication data in a target storage space. In addition, the store module stores a pointer to the target storage space in a system register. A retrieve module retrieves the authentication data from the target storage space using the pointer. An authentication module automatically authenticates a user with the authentication data. | 09-02-2010 |
20110219338 | SYSTEM, METHOD AND COMPUTER PROGRAM PRODUCT FOR PERFORMING AN ACTION ASSOCIATED WITH A RECORD - In accordance with embodiments, there are provided mechanisms and methods for performing an action associated with a record. These mechanisms and methods for performing an action associated with a record can enable improved data access, simplify and expedite a user's workflow, etc. | 09-08-2011 |
20110225527 | CONFIGURABLE HIGHLIGHTS PANEL FOR DISPLAY OF DATABASE RECORDS - Systems and methods for configuring a UI display layout for displaying record fields in a multi-tenant on-demand database service. A data record is initially displayed on a first portion of a user interface display, and an identification of a set of one or more fields of the data record is received, e.g., from a user. A selection of a display configuration for the set of identified fields is also received, e.g., from a user. The display configuration may include one or more columns, each column having one or more rows, wherein the display configuration identifies, for each of the set of fields, in which column and row the field is to be displayed. Data for the set of fields based on the selected display configuration is then displayed on a second portion of the user interface display which may include a collapsible display panel. | 09-15-2011 |
20130091217 | Computer Implemented Methods And Apparatus For Informing A User Of Social Network Data When The Data Is Relevant To The User - Disclosed are examples of apparatus, methods, and computer readable storage media for informing one or more users of social network data such as group data when the data is relevant to the user(s). For example, when one or more keywords are identified as being associated with both a group of an online social network and the user, a communication with information identifying the group data can be generated and provided to a display device accessible by the user. In another example, social network data is associated with an entity of the online social network, and the entity is not being followed by the user. Social network data identified as related to one or more keywords can be provided to a display device in a suitable presentation accessible by the user. | 04-11-2013 |
20140317131 | SYSTEM AND METHOD FOR ASSOCIATING DYNAMIC OBJECTS WITH DATABASE RECORDS - Some embodiments of the present invention include determining at least one input requirement of a dynamic object and associating the at least one input requirement with a group of related information in a database. The dynamic object may then be configured to operate based on information being accessed from the group of related information. This may include configuring the software code associated with the dynamic object to reflect each information as it is being accessed from the group of related information. | 10-23-2014 |
Patent application number | Description | Published |
20110113092 | Resolving Conflicts While Synchronizing Configuration Information Among Multiple Clients - A user of multiple client devices (clients) makes application configuration changes on the clients from time to time. The configuration changes are stored in a local event log on each client, as well as in a synchronization server. When one of the clients connects to the synchronization server, for example when the user logs into the synchronization server while using a respective client, the configuration information in the server and client is synchronized. Conflicts, if any, in the configuration changes for a respective application are resolved in accordance with a conflict resolution procedure or conflict resolution rules associated with that application. | 05-12-2011 |
20120089710 | Synchronizing Configuration Information Among Multiple Clients - A user of multiple client devices (clients) makes application configuration changes on the clients from time to time. The configuration changes are stored in a local event log on each client, as well as in a synchronization server. When one of the clients connects to the synchronization server, for example when the user logs into the synchronization server while using a respective client, the configuration information in the server and client is synchronized. Conflicts, if any, in the configuration changes for a respective application are resolved in accordance with a conflict resolution procedure or conflict resolution rules associated with that application. | 04-12-2012 |
20130283375 | Browser System and Method for Warning Users of Potentially Fraudulent Websites - A user is warned of a potentially fraudulent document, such as a webpage, by a warning message that is overlaid on top of the document and of the browser chrome. The warning message is associated with a warning icon displayed in the browser chrome. The potentially fraudulent document is rendered in the browser such that the links within are not accessible to the user. The rendering may include superimposing an image over the document or rendering a snapshot of the document instead of the document itself. | 10-24-2013 |
Patent application number | Description | Published |
20090037393 | System and Method of Accessing a Document Efficiently Through Multi-Tier Web Caching - Upon receipt of a document request, a client assistant examines its cache for the document. If not successful, a server searches for the requested document in its cache. If the server copy is still not fresh or not found, the server seeks the document from its host. If the host cannot provide the copy, the server seeks it from a document repository. Certain documents are identified from the document repository as being fresh or stable. Information about each these identified documents is transmitted to the server which inserts entries into an index if the index does not already contain an entry for the document. If and when this particular document is requested, the document will not be present in the server, however the server will contain an entry directing the server to obtain the document from the document repository rather than the document's web host. | 02-05-2009 |
20120271852 | System and Method of Accessing a Document Efficiently Through Multi-Tier Web Caching - Upon receipt of a document request, a client assistant examines its cache for the document. If not successful, a server searches for the requested document in its cache. If the server copy is still not fresh or not found, the server seeks the document from its host. If the host cannot provide the copy, the server seeks it from a document repository. Certain documents are identified from the document repository as being fresh or stable. Information about each of these identified documents is transmitted to the server which inserts entries into an index if the index does not already contain an entry for the document. If and when this particular document is requested, the document will not be present in the server, however the server will contain an entry directing the server to obtain the document from the document repository rather than the document's web host. | 10-25-2012 |
Patent application number | Description | Published |
20080269070 | METHOD FOR RAPIDLY SCREENING MICROBIAL HOSTS TO IDENTIFY CERTAIN STRAINS WITH IMPROVED YIELD AND/OR QUALITY IN THE EXPRESSION OF HETEROLOGOUS PROTEINS - The present invention provides an array for rapidly identifying a host cell population capable of producing heterologous protein with improved yield and/or quality. The array comprises one or more host cell populations that have been genetically modified to increase the expression of one or more target genes involved in protein production, decrease the expression of one or more target genes involved in protein degradation, or both. One or more of the strains in the array may express the heterologous protein of interest in a periplasm compartment, or may secrete the heterologous protein extracellularly through an outer cell wall. The strain arrays are useful for screening for improved expression of any protein of interest, including therapeutic proteins, hormones, a growth factors, extracellular receptors or ligands, proteases, kinases, blood proteins, chemokines, cytokines, antibodies and the like. | 10-30-2008 |
20090062143 | TRANSLATION INITIATION REGION SEQUENCES FOR OPTIMAL EXPRESSION OF HETEROLOGOUS PROTEINS - The present invention provides methods and compositions for producing heterologous protein with improved yield and/or quality. A library of randomized ribosomal binding site sequences is provided for the identification of a translation initiation region sequence optimal for expression of the heterologous protein. Also provided are novel ribosomal binding site sequences, and vectors and host cells having those sequences. The library of randomized sequences is useful for screening for improved expression of any protein of interest, including therapeutic proteins, hormones, a growth factors, extracellular receptors or ligands, proteases, kinases, blood proteins, chemokines, cytokines, antibodies and the like. | 03-05-2009 |
20090093626 | High Viscosity Xanthan Polymer Preparations - Increasing the molecular length of xanthan polymer makes a higher viscosity xanthan composition. Xanthan with higher specific viscosity characteristics provides more viscosity at equivalent concentration in food, industrial and oilfield applications. Methods for increasing the viscosity of xanthan include inducing particular key genes and increasing copy number of particular key genes. | 04-09-2009 |
20090325230 | PROTEIN EXPRESSION SYSTEMS - The present invention provides an improved expression system for the production of recombinant polypeptides utilizing auxotrophic selectable markers. In addition, the present invention provides improved recombinant protein production in host cells through the improved regulation of expression. | 12-31-2009 |
20100137162 | Method for Rapidly Screening Microbial Hosts to Identify Certain Strains with Improved Yield and/or Quality in the Expression of Heterologous Proteins - The present invention provides an array for rapidly identifying a host cell population capable of producing heterologous protein with improved yield and/or quality. The array comprises one or more host cell populations that have been genetically modified to increase the expression of one or more target genes involved in protein production, decrease the expression of one or more target genes involved in protein degradation, or both. One or more of the strains in the array may express the heterologous protein of interest in a periplasm compartment, or may secrete the heterologous protein extracellularly through an outer cell wall. The strain arrays are useful for screening for improved expression of any protein of interest, including therapeutic proteins, hormones, a growth factors, extracellular receptors or ligands, proteases, kinases, blood proteins, chemokines, cytokines, antibodies and the like. | 06-03-2010 |
20110020830 | DESIGN FOR RAPIDLY CLONING ONE OR MORE POLYPEPTIDE CHAINS INTO AN EXPRESSION SYSTEM - The present invention provides methods and compositions for the generation and identification of expression constructs that can be used to express sufficient levels of a polypeptide of interest. The compositions include a population of expression vectors, wherein members of the population have a type IIS restriction enzyme recognition site adjacent to a regulatory sequence, and wherein the regulatory element is distinct in at least two members of the population of expression vectors. In various embodiments, the expression vectors further comprise a polynucleotide sequence encoding a polypeptide of interest, wherein the polynucleotide encoding the polypeptide, the polynucleotide of the regulatory sequence, or both, are distinct in at least two members of the population. The compositions are useful for identifying a combination of coding sequences and/or regulatory elements useful for the heterologous expression of the polypeptide of interest. | 01-27-2011 |
20110111482 | High Viscosity Xanthan Polymer Preparations - Increasing the molecular length of xanthan polymer makes a higher viscosity xanthan composition. Xanthan with higher specific viscosity characteristics provides more viscosity at equivalent concentration in food, industrial and oilfield applications. Methods for increasing the viscosity of xanthan include inducing particular key genes and increasing copy number of particular key genes. | 05-12-2011 |
20130323780 | PROMOTERS AND TERMINATORS FOR USE IN EUKARYOTIC CELLS - The present invention provides novel promoter and terminator sequences for use in heterologous gene expression in eukaryotic cells, such as algal cells. The invention further provides expression cassettes comprising a promoter, as described herein, operably linked to a heterologous gene. The invention further provides expression vectors and host eukaryotic cells, such as algal cells, for expressing a protein encoded by the heterologous gene; and methods for identifying promoters. | 12-05-2013 |
20140106417 | DGAT GENES AND METHODS OF USE FOR TRIGLYCERIDE PRODUCTION IN RECOMBINANT MICROORGANISMS - The present invention provides novel diacylglycerol acyltransferase (DGAT) genes, including novel genes encoding localization peptides. The present invention also provides recombinant cells, such as algae, transformed with DGAT genes and methods of using such recombinant cells to produce triglyceride. | 04-17-2014 |
20140154806 | TETRASELMIS PROMOTERS AND TERMINATORS FOR USE IN EUKARYOTIC CELLS - The present invention provides novel promoter and terminator sequences for use in gene expression in eukaryotic cells, such as algal cells. The invention further provides expression cassettes comprising a promoter, as described herein, operably linked to a gene. The invention further provides expression vectors and host eukaryotic cells, such as algal cells, for expressing a protein encoded by the gene; and methods for stably transforming eukaryotic algae such as | 06-05-2014 |
Patent application number | Description | Published |
20080268527 | Mutant bacterial strains of the genus sphingomonas deficient in production of polyhydroxybutyrate and a process of clarification of sphingans and compositions thereof - The invention relates to mutant strains of the genus | 10-30-2008 |
20090162899 | MANNITOL INDUCED PROMOTER SYSTEMS IN BACTERIAL HOST CELLS - The present invention provides methods for producing recombinant peptides in a bacterial host utilizing a mannitol, arabitol, glucitol, or glycerol-inducible promoter, wherein the host bacterial cell that produces the peptide has been rendered incapable of degrading or metabolizing mannitol, arabitol, or glucitol, or derivatives or analogues thereof. The present invention provides bacterial cells that have been genetically altered to inhibit the metabolism or degradation of mannitol, glucitol, or arabitol, or derivatives or analogues thereof. The present invention utilizes mannitol, arabitol, glucitol, or glycerol to induce expression of a target polypeptide from an inducible promoter, allowing for the use of an inexpensive and stable carbon source inducer in the fermentation processes for the production of recombinant peptides. | 06-25-2009 |
20110009611 | CLARIFICATION OF SPHINGANS AND COMPOSITIONS THEREOF - The invention relates to mutant strains of the genus | 01-13-2011 |
Patent application number | Description | Published |
20090076166 | ENTERICALLY COATED CYSTAMINE, CYSTEAMINE AND DERIVATIVES THEREOF - 8 The disclosure provides oral cysteamine and cystamine formulations useful for treating cystinosis and neurodegenerative diseases and disorders. The formulations provide controlled release compositions that improve quality of life and reduced side-effects. | 03-19-2009 |
20100303870 | METHODS OF TREATING NON-ALCOHOLIC STEATOHEPATITIS (NASH) USING CYSTEAMINE PRODUCTS - The disclosure relates, in general, to treatment of fatty liver disorders comprising administering compositions comprising cysteamine products. The disclosure provides administration of enterically coated cysteamine compositions to treat fatty liver disorders, such as non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). | 12-02-2010 |
20120015005 | METHODS OF TREATING NON-ALCOHOLIC STEATOHEPATITIS (NASH) USING CYSTEAMINE PRODUCTS - The disclosure relates, in general, to treatment of fatty liver disorders comprising administering compositions comprising cysteamine products. The disclosure provides administration of enterically coated cysteamine compositions to treat fatty liver disorders, such as non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). | 01-19-2012 |
20120015038 | ENTERICALLY COATED CYSTEAMINE, CYSTAMINE AND DERIVATIVES THEREOF - The disclosure provides oral cysteamine and cystamine formulations useful for treating cystinosis and neurodegenerative diseases and disorders. The formulations provide controlled release compositions that improve quality of life and reduced side-effects. | 01-19-2012 |
20120237599 | ENTERICALLY COATED CYSTEAMINE, CYSTAMINE AND DERIVATIVES THEREOF - The disclosure provides oral cysteamine and cystamine formulations useful for treating cystinosis and neurodegenerative diseases and disorders. The formulations provide controlled release compositions that improve quality of life and reduced side-effects. | 09-20-2012 |
20130183351 | METHODS OF TREATING NON-ALCOHOLIC STEATOHEPATITIS (NASH) USING CYSTEAMINE PRODUCTS - The disclosure relates, in general, to treatment of fatty liver disorders comprising administering compositions comprising cysteamine products. The disclosure provides administration of enterically coated cysteamine compositions to treat fatty liver disorders, such as non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). | 07-18-2013 |
Patent application number | Description | Published |
20100273616 | Complete body fitness machine - A “Complete Body Fitness Machine” that provides for a muscle building workout as well as a cardiovascular workout for the total body consists generally of an adjustable seat and two arms on either side, which are adjustable in height and have an infinitely and independently variable resistance possible in either clockwise or counterclockwise rotation. The arms are designed to have several types of mechanisms attached, so as to be able to work with a variety of body parts including, but not limited to, hands, arms, legs, feet, torso, neck and shoulders. When the proper attachment is used, the resistance for each direction of rotation of the arm is set, and the exercise is conducted. Depending on the workout desired, the seat and arms could be adjusted to different positions as well as the seat can be free-moving. This, combined with the fact that the arms can rotate 360-degrees, allows the user to simulate rotational cardiovascular exercises such as cycling, rowing, rotation of the arms in a circular motion (similarly to how the legs rotate in the cycling motion), and even running. The two independent arms are infinitely and separately adjusted for resistance in either rotational direction. This means that the body's natural design of using opposing muscle groups such as the bicep and triceps to bend and straighten the arm can be not only be utilized, but also maximized for efficiency of operation and workout. | 10-28-2010 |
Patent application number | Description | Published |
20140095257 | ANALYZING USER ACTIONS IN A SOCIAL GRAPH - A method includes collecting user interaction data for one or more users in an extended social network, clustering each of the one or more users into one or more groups of users based on the collected user interaction data for each user, wherein each of the one or more users is clustered into no more than one group of the one or more groups of users, monitoring, over a time period, a change in a size of each group of users at one or more increments of the time period and generating observation information for each group of users during each of the one or more increments of the time period, wherein the observation information is based on the monitored change in size of each group of users. | 04-03-2014 |
20140245183 | METHOD FOR ONE-CLICK SUBSCRIBING TO MULTIPLE CHANNELS OF INFORMATION ON A SINGLE TOPIC - A subscription to multiple channels of information on a single topic is performed. A topic of interest is received via a user interface. A user interface element is presented via the user interface to facilitate a user subscription to a plurality of channels associated with the topic of interest without having to subscribe separately to each channel. A user selection of the user interface element is received and a user is subscribed to the plurality of channels in response to the received user selection. | 08-28-2014 |
20140310353 | CONTENT SHARING PLATFORM PLAYLISTS AND SUBSCRIPTIONS BASED ON USER HISTORY - A method for generating content sharing platform playlists and subscriptions based on user history is disclosed. The method includes identifying one or more entities of a content sharing platform to which a user is not subscribed, providing a user interface (UI) associated with the user, the UI displaying the identified one or more entities as recommended suggestions to the user, receiving, by the user via the UI, an indication of a selection of an entity of the identified one or more entities, generating a subscription to the selected entity for the user on the content sharing platform, using content items associated with the subscribed entity to originate a playlist for the user, and providing the playlist on the UI associated with the user. | 10-16-2014 |
Patent application number | Description | Published |
20080243138 | INSERTION SYSTEM FOR CORNEAL IMPLANTS - Provided therein are apparatuses, systems and methods for storing and retrieving a corneal implant and for delivering the corneal implant in or on the cornea. In an embodiment, a insertion system comprises an inserter for delivering a corneal implant to a desired location in or on the cornea. The inserter has a holding space at its distal end for holding a corneal implant therein. A solution may substantially fill the holding space with the corneal implant to keep the implant hydrated and to hold the implant in the holding space by the surface tension of the solution. The corneal implant may be preloaded in the holding space of the inserter and stored in a storage container filled with storage fluid, e.g., saline, until use. To deliver the corneal implant, the inserter is positioned at the desired location, and the corneal implant released from the holding space of the inserter. | 10-02-2008 |
20080262610 | BIOMECHANICAL DESIGN OF INTRACORNEAL INLAYS - Provided herein are intracorneal inlays for correcting vision impairments by altering the shape of the anterior corneal surface. The physical design of the inlay to induce the desired change of the anterior corneal surface includes consideration of the biomechanical response of the corneal tissue to the physical shape of the inlay. This biomechanical response can differ depending on the thickness, diameter, and profile of the inlay. In one embodiment, inlays having diameters smaller than the pupil are provided for correcting presbyopia. To provide near vision, an inlay is implanted centrally in the cornea to induce an “effect” zone on the anterior corneal surface, within which diopter power is increased. Distance vision is provided by a region of the cornea peripheral to the “effect” zone. In another embodiment, small diameter inlays are provided that induce “effect” zones on the anterior corneal surface that are much larger in diameter than the inlays. | 10-23-2008 |
20110218623 | Small Diameter Inlays - Small diameter corneal inlays adapted to change the corneal surface curvature to provide central near vision and peripheral distance vision. | 09-08-2011 |
20120046680 | Methods and Devices for Forming Corneal Channels - Instruments for creating a corneal channel and methods of use. | 02-23-2012 |
20120165823 | Insertion System for Corneal Implants - Provided therein are apparatuses, systems and methods for storing and retrieving a corneal implant and for delivering the corneal implant in or on the cornea. In an embodiment, a insertion system comprises an inserter for delivering a corneal implant to a desired location in or on the cornea. The inserter has a holding space at its distal end for holding a corneal implant therein. A solution may substantially fill the holding space with the corneal implant to keep the implant hydrated and to hold the implant in the holding space by the surface tension of the solution. The corneal implant may be preloaded in the holding space of the inserter and stored in a storage container filled with storage fluid, e.g., saline, until use. To deliver the corneal implant, the inserter is positioned at the desired location, and the corneal implant released from the holding space of the inserter. | 06-28-2012 |
20130023892 | Corneal Implant Retaining Devices and Methods of Use - Corneal implant retaining devices and their methods of use. The retaining devices can be a cap adapted to be disposed over a portion of a corneal implant insertion device. | 01-24-2013 |
20130123916 | Corneal Implant Storage and Delivery Devices - Devices and methods for handling and depositing corneal implants onto corneal tissue. Devices and methods for packaging and storing corneal implants. | 05-16-2013 |
20130253527 | Corneal Implant Inserters and Methods of Use - Devices that are adapted to insert corneal implants onto corneal tissue. Methods of using the devices include inserting the corneal implant into a pocket created in the cornea. Methods of use also include inserting the corneal implant onto corneal tissue after a flap has been created in the cornea. The devices can be adapted to deliver fluid to an implant holding space to at least assist in the deployment of the implant from the holding space and onto corneal tissue. | 09-26-2013 |
20130281993 | Methods and Devices for Forming Corneal Channels - Instruments for creating a corneal channel and methods of use. | 10-24-2013 |
20140135915 | Corneal Implant Applicators - Devices and methods for handling and depositing corneal implants onto corneal tissue. Devices and methods for packaging and storing corneal implants. | 05-15-2014 |
20140257477 | CORNEAL IMPLANT STORAGE AND DELIVERY DEVICES - Devices and methods for handling and depositing corneal implants onto corneal tissue. Devices and methods for packaging and storing corneal implants. | 09-11-2014 |
Patent application number | Description | Published |
20110125243 | STENT HAVING AN EXPANDABLE WEB STRUCTURE - A stent comprises a tubular flexible body composed of a web structure that is expandable from a contracted delivery configuration to a deployed configuration and that comprises neighboring web patterns of alternating concavities extending circumferentially and adjoined by X-shaped transition sections. The web pattern may comprise either arcuate struts interconnected by bends, or a plurality of substantially straight sections with the transition sections formed by the junctions between pairs of adjacent bends of opposite curvatures. | 05-26-2011 |
20110238167 | METHODS OF CONDITIONING SHEET BIOPROSTHETIC TISSUE - Methods for the conditioning of bioprosthetic material employ bovine pericardial membrane. A laser directed at the fibrous surface of the membrane and moved relative thereto reduces the thickness of the membrane to a specific uniform thickness and smoothes the surface. The wavelength, power and pulse rate of the laser are selected which will smooth the fibrous surface as well as ablate the surface to the appropriate thickness. Alternatively, a dermatome is used to remove a layer of material from the fibrous surface of the membrane. Thinning may also employ compression. Stepwise compression with cross-linking to stabilize the membrane is used to avoid damaging the membrane through inelastic compression. Rather, the membrane is bound in the elastic compressed state through addition cross-linking. The foregoing several thinning techniques may be employed together to achieve strong thin membranes. The finally thinned membrane may then be treated by capping of calcification nucleation sites and borohydride reduction. The leaflets may be formed to have more than one region of uniform thickness, such as a thicker peripheral sewing region. | 09-29-2011 |
20120253386 | APICAL PUNCTURE ACCESS AND CLOSURE SYSTEM - A device, system, and method for providing access to, and sealing of, a body organ includes an implant device. An implant device has a main body having an internal access lumen, with a plurality of prongs extending from a distal end of the main body. The main body can include two lumens, one slidable within the other, to form a single continuous lumen with an adjustable length. The main body has an expanded configuration with an expanded diameter, and an unexpanded configuration with an unexpanded diameter. The prongs have a generally straight configuration where they extend distally of the distal end of the main body, and a bent configuration where the prongs bend around so that their tips extend proximally of the distal end of the main body. The device may include a hemostatic barrier to prevent fluid leakage therethrough when the main body is in the unexpanded configuration. | 10-04-2012 |
20130110097 | METHODS OF CONDITIONING SHEET BIOPROSTHETIC TISSUE | 05-02-2013 |
20130116676 | METHODS OF CONDITIONING SHEET BIOPROSTHETIC TISSUE - Methods for the conditioning of bioprosthetic material employ bovine pericardial membrane. A laser directed at the fibrous surface of the membrane and moved relative thereto reduces the thickness of the membrane to a specific uniform thickness and smoothes the surface. The wavelength, power and pulse rate of the laser are selected which will smooth the fibrous surface as well as ablate the surface to the appropriate thickness. Alternatively, a dermatome is used to remove a layer of material from the fibrous surface of the membrane. Thinning may also employ compression. Stepwise compression with cross-linking to stabilize the membrane is used to avoid damaging the membrane through inelastic compression. Rather, the membrane is bound in the elastic compressed state through addition cross-linking. The foregoing several thinning techniques may be employed together to achieve strong thin membranes. | 05-09-2013 |
20130150869 | SELF-CINCHING SURGICAL CLIPS AND DELIVERY SYSTEM - A device and method for deploying self-cinching surgical clips. The device accesses at least two layers of tissue or material from only one side of the tissue or material and punctures through the two layers of tissue or material. The various configurations of clips disclosed herein are made of a superelastic material such as Nitinol, and have a constrained and a relaxed state, and no sharp edges or tips so as to reduce tissue irritation following deployment. The clip is disposed within the housing of the delivery device and held in a constrained state by a tube assembly until deployment wherein the clip assumes its relaxed state, where the ends of the clip are brought into close approximation, thereby securing the layers of tissue or material together. | 06-13-2013 |
20130331930 | SYSTEMS FOR IMPLANTING ANNULOPLASTY RINGS WITH MICROANCHORS - Disclosed systems for implanting annuloplasty rings and other prosthetic devices can comprise a plurality of microanchors, sutures threaded through the microanchors, the sutures passing through the prosthetic device, individual microanchor guides, such as tubes or spears, for each microanchor that contain the microanchors during delivery and allow for positioning and deployment of the microanchors into annular tissue. The systems can also comprise a bracket that is temporarily coupled to the prosthetic device, holds the plurality of microanchor guides in position relative to one another and relative to the prosthetic device, and/or guides the sutures passing through the prosthetic device. The prosthetic device can include suture locking mechanisms to secure the prosthetic device to the sutures and to the implanted microanchors after the deployment devices have been removed. | 12-12-2013 |
20140031864 | SUTURE SECUREMENT DEVICES - Disclosed herein are exemplary embodiments of suture securement devices that replace the need to tie knots in sutures. Some embodiments comprise an annular outer body and one or more suture engagement tabs extending inwardly from the outer body. The devices can comprise a superelastic and/or shape-memory material and have a generally in-plane initial configuration. The suture engagement portions are deformable out-of-plane to an active configuration with the outer body compressed and the tabs interlocked with each other. The device can be heat-set in the deformed configuration. The interlocked tabs exert a pinching force on sutures passing between them that restricts the sutures from sliding through the opening in one longitudinal direction. | 01-30-2014 |
Patent application number | Description | Published |
20120177261 | Artificial intelligence system for genetic analysis - The present invention provides a complete artificial intelligence system for the acquisition and analysis of nucleic acid array hybridization information. The system includes a central data processing facility and one or more user facilities, linked by encrypted connections. Each user facility may include an optical scanning system to collect hybridization signals from a nucleic acid array, an image processing system to convert the optical data into a set of hybridization parameters, a connection to a data network, and a user interface to display, manipulate, search, and analyze hybridization information. This system reads data from a nucleic acid microarray, analyzes test results, evaluates patient risk for various ailments, and recommends methods of treatment. The automated artificial intelligence system is a real time, dynamic decision making tool that can be used in conjunction with a clinical analysis system, and with the information obtained in a research and development environment. | 07-12-2012 |
20140177930 | Artificial Intelligence System for Genetic Analysis - The present invention provides a complete artificial intelligence system for the acquisition and analysis of nucleic acid array hybridization information. The system is divided into at least one central data processing facility and one or more user facilities, linked by encrypted network connections or similar links. Each user facility may include an optical scanning system to collect hybridization signals from a nucleic acid array, an image processing system to convert the optical data into a set of hybridization parameters, a connection to a data network, and a user interface to display, manipulate, search, and analyze hybridization information. This system reads data from a gene chip or DNA microarray, or a proteomics chip, analyzes test results based on maintained parameters, evaluates patient risk for various ailments, recommends methods of treatment, presents information to medical and/or private individuals, and notifies test participants when new treatment becomes available. The test results may be used to perform individual diagnostics, longitudinal studies, population studies, or a wide variety of statistical analyses of patient data. The automated artificial intelligence system is a real time, dynamic decision making tool that can be used not only in conjunction with a clinical analysis system, but also with the information obtained in a research and development environment. Access to this system allows the user(s) to look at both clinical and non-clinical information. Most importantly, the system is intelligent and possesses the capability to interpret the information obtained. The system presents the information primarily via a secured encrypted Web interface, such as the Internet. The information is also presented in a retrievable format, such as electronic or paper format, using various computing technologies. | 06-26-2014 |
Patent application number | Description | Published |
20090177618 | Record tagging, storage and filtering system and method - A record tagging, storage and filtering system and method that permits paper records to be tagged, stored and filtered according to user criteria. The system includes a scanning module, a central server, one or more user workstations and an optical character recognition server. After scanning, the records may then be serialized and categorized by project, and then supplemented automatically by the system with a hypertext data file. The system provides for the manual input of additional hypertext data and merger of the hypertext data file with other records in the project. The end user may then search and/or filter records according to information contained in the hypertext data file. Because the pages may be sorted according to user criteria, the user may shuffle through pages from various different documents, thus allowing them to quickly retrieve the records they need and perform such actions as trend-spotting. | 07-09-2009 |
20130268568 | RECORDS MANAGEMENT SYSTEM AND METHODS - A records management system and method that permits paper records to be tagged, stored and retrieved according to user criteria. The system includes a scanning module, a central server, one or more user workstations and an optical character recognition server. After scanning, the records may then be serialized and categorized by project, and then supplemented automatically by the system with a hypertext data file. The system provides for the manual input of additional hypertext data and merger of the hypertext data file with other records in the project. The end user may then search and/or filter records according to information contained in the hypertext data file. Output from the system may include summary excerpts whereby summaries for data contained in select pages of each document in a project are associated with at least dates, page numbers, and providers for the data. | 10-10-2013 |
20140082111 | DOCUMENT DELIVERY SYSTEM WITH EMAIL UPLOADER FOR AUTOMATIC STORAGE OF DOCUMENTS IN A USER ACCOUNT - A computer program product and method for delivery of electronic and physical documents, with an email interface for uploading documents to be automatically stored in a user's account. The system may receive uploaded electronic documents for delivery to one or more electronic and/or physical endpoints. After the electronic documents have been received, the delivery system determines whether the received electronic documents should be delivered electronically or physically, based on recipient data in the delivery system. If physical documents are to be delivered, the system may intelligently decide whether to aggregate some documents into a multi-document package. The system provides for delivery by commercial carrier, postal service, and/or electronic delivery. Optional services available to the sender include, but are not limited to, certified mail, proof of service, and email confirmation. | 03-20-2014 |
20140250163 | DOCUMENT DELIVERY WITH MULTIPLE ADDRESSING AND DELIVERY OPTIONS - A computer program product and method for delivery of electronic and physical documents, with multiple addressing and delivery options. The system may receive uploaded electronic documents and deliver the documents electronically based on only a substantially correct physical address, or based on only a username. The recipient may choose the method of delivery of the uploaded documents. A tag may be input in order to associate the received electronic documents with others having the same tag. Optional services include, but are not limited to, e-signatures, certified mail, electronic and physical proofs of service, and email confirmation. | 09-04-2014 |
Patent application number | Description | Published |
20090191951 | Validation of Network Devices - A system and method for actively validating a network device is provided. Nodes in a network game community are prompted to engage in interrogation and response to facilitate the identification of nodes operating with hacked, modified and non-typical game configurations. In one embodiment, a query is presented to a user's machine which triggers a response, and where the response indicates whether certain data at the user is valid and wherein invalid data is suggestive of illegal community behavior. Functions are triggered and data is queried to determine whether the state of game environment is operating according to known metrics or constraints. Various queries to test user integrity include memory peeks, confirmation of location of functions in memory, memory hashing, profiling of threads operating on the user machine, and combinations thereof. Queries may be actively initiated by a server, peer, peer group or combinations thereof and may be scheduled on a routine basis, triggered in response to passive listening, and via collaborating users who suspect cheat activity. | 07-30-2009 |
20110269547 | Maintaining Community Integrity - Various metrics as may be deployed in an active, passive, or hybrid validation architecture are disclosed. A computing device configured to monitor network game activity may identify an inconsistency between user game data and a particular game metric governing a particular aspect of the network gaming environment. Upon identification of an inconsistency between game data and a game metric, which may indicative of illicit game play, a validation process (e.g., active, passive, and/or hybrid) may be implemented to further confirm the existence of illicit game. Alternatively, an action to maintain integrity of the gaming community may be executed without further confirmation whereby a purportedly illicit game device may be ejected from the network. | 11-03-2011 |
20120088585 | VALIDATION OF NETWORK DEVICES - A system and method for actively validating a network device is provided. Nodes in a network game community are prompted to engage in interrogation and response to facilitate the identification of nodes operating with hacked, modified and non-typical game configurations. In one embodiment, a query is presented to a user's machine which triggers a response, and where the response indicates whether certain data at the user is valid and wherein invalid data is suggestive of illegal community behavior. Functions are triggered and data is queried to determine whether the state of game environment is operating according to known metrics or constraints. | 04-12-2012 |
20140187316 | DEFINING NEW RULES FOR VALIDATION OF NETWORK DEVICES - A system and method for actively validating a network device is provided. Nodes in a network game community are prompted to engage in interrogation and response to facilitate the identification of nodes operating with hacked, modified and non-typical game configurations. In one embodiment, a query is presented to a user's machine which triggers a response, and where the response indicates whether certain data at the user is valid and wherein invalid data is suggestive of illegal community behavior. Functions are triggered and data is queried to determine whether the state of game environment is operating according to known metrics or constraints. | 07-03-2014 |
20140309024 | INVALIDATING NETWORK DEVICES WITH ILLICIT PERIPHERALS - A system and method for passively validating network game users is provided. Data indicative of game behavior and actions at one or more nodes interacting with a network game in a network game community are monitored. The data is evaluated to determine whether the one or more nodes are adhering to one or more rules associated with the network game. Data indicative of illicit game behavior may trigger various responses including invalidation of the node engaged in the illicit behavior. Alternatively, a query may be generated to further identify the nature and/or actual existence of illicit behavior at the node. Monitoring of game data may occur at a server, a peer, as part of a peer group or combinations thereof, which may be based on routine schedule or part of constant game behavior monitoring. | 10-16-2014 |