Sarasam
Aparna R. Sarasam, West Lafayette, IN US
Patent application number | Description | Published |
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20130302381 | Implantable Medical Devices Including a Water-Insoluble Therapeutic Agent - A medical device includes an implantable structure and a coating layer including a water-insoluble therapeutic agent and one or more additives selected from xylitol, iodine or Ethylenediaminetetraacetic acid (EDTA), and physiologically-acceptable salts thereof. The one or more additives can be present in an amount effective to increase the rate of release of the water-insoluble therapeutic agent from the coating layer. The implantable medical device structure can be an expandable structure such as a balloon or stent. Also described are methods of making and using such implantable medical devices and coating layers. | 11-14-2013 |
Aparna R. Sarasam, Longmont, CO US
Patent application number | Description | Published |
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20130303983 | COATED MEDICAL DEVICES INCLUDING A WATER-INSOLUBLE THERAPEUTIC AGENT - A medical device includes an implantable structure and a coating layer including a water-insoluble therapeutic agent and one or more additives selected from heparin, heparan sulfate, dextran and dextran sulfate, and physiologically-acceptable salts thereof. The one or more additives can be present in an amount effective to increase the rate of release of the water-insoluble therapeutic agent from the coating layer. The implantable medical device structure can be an expandable structure such as a balloon or stent. Also described are methods of making and using such implantable medical devices and coating layers. | 11-14-2013 |
Aparna Reddy Sarasam, West Lafayette, IN US
Patent application number | Description | Published |
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20100049296 | Implantable medical device coatings with biodegradable elastomer and releasable taxane agent - A coated medical device, such as a stent, that elutes a taxane agent in a controlled manner is provided. In one embodiment, the taxane agent is paclitaxel and at least a portion of the paclitaxel is present in a dihydrate solid form. The medical device may be coated with a layer including a taxane agent and a layer of bioabsorbable elastomer over the layer including the taxane agent. Methods of manufacturing and using the coated medical device are also provided. | 02-25-2010 |