Patent application number | Description | Published |
20090165035 | METHOD AND SYSTEM OF DEVICE LEVEL PROGRAM INSERTION - Method and system of inserting commercials or program within content feeds. The commercials may be inserted in an optimized manner on a host device so as to permit device level commercial insertion. Instructions or other information may be pre-loaded for a number of insertion opportunities so that processing demands on the host device at the time of insertion can be limited. | 06-25-2009 |
20090171711 | METHOD AND SYSTEM OF MANAGING TRANSACTIONS - Method and system of managing transactions. The transactions may be executed over different networks, such as but not limited to networks associated with different cable television service providers. The transactions may be monitored so that product purchases may be facilitated without requiring product vendors to support electronic communications with each of the networks. The transactions may also be monitored to tabulate metrics and other measurables reported from the different networks in such a manner that the vendors can receive a report without having to understand the reporting and tabulating means used by the different networks to measure the same metrics. | 07-02-2009 |
20100150527 | SEGMENT BOUNDARY OBFUSCATION - A method and system for obfuscating segment boundary markers, such as but not limited to obfuscating boundary markers used to identify beginning and/or ending boundaries of a sequence of segments forming a programming event. The obfuscation may be achieved by embedding decoy and offset boundary markers within the sequence of segments. | 06-17-2010 |
20120002111 | SYNCHRONIZATION OF 2ND SCREEN APPLICATIONS - A method and system to synchronize a user experience between multiple output devices. The synchronization may be facilitated with communications between the multiple output devices timed relative to content, event, actions, and occurrences taking place within media being accessed by at least one of the multiple output devices. | 01-05-2012 |
20130064525 | METHOD OF MODIFYING PLAY OF AN ORIGINAL CONTENT FORM - A method of facilitating modified content play such that modification actions may be implemented during play of original content form. The modification actions may be specified by users to modify the original content form. The modification may be disseminated to subscribers or other users desiring similar content modifications. The method may be useful in social networking systems to allow social members to share commentary and otherwise modify original content forms to include their personal reflections. | 03-14-2013 |
20130107117 | TELEVISION DISPLAYED MESSAGING | 05-02-2013 |
Patent application number | Description | Published |
20150127472 | FUTURE DECISIONING FOR CREATIVE SLOTS - A future decisioning module receives, from a user agent, a call requesting a creative for a first slot of the plurality of slots in a template. The future decisioning module generates bid requests for each of the plurality of slots and receives, from one or more bidders, responses to the bid requests, the responses comprising prices for the plurality of slots. The future decisioning module performs a yield optimization based on the responses to the bid requests to determine creatives for each of the plurality of slots that will optimize a payout (or value) for the template and serves, to the user agent, the determined creatives for each of the plurality of slots. | 05-07-2015 |
20150193831 | FUTURE DECISIONING FOR CREATIVE SLOTS - A future decisioning module receives, from a user agent, a call requesting a creative for a first slot of the plurality of slots in a template. The future decisioning module generates bid requests for each of the plurality of slots and receives, from one or more bidders, responses to the bid requests, the responses comprising prices for the plurality of slots. The future decisioning module performs a yield optimization based on the responses to the bid requests to determine creatives for each of the plurality of slots that will optimize a payout (or value) for the template and serves, to the user agent, the determined creatives for each of the plurality of slots. | 07-09-2015 |
20160104193 | UNIVERSAL CROSS-CHANNEL AUDIENCE ADDRESSABILITY - An addressability module provides an email template to a publisher for sending an email to a recipient, wherein the email template associates an identifier of the recipient with a content link in the email, and wherein the content link is associated with a content landing page. The addressability module receives a call from the content landing page requesting a creative for display on the content landing page, wherein the call comprises the identifier of the recipient, the identifier having been passed from the email to the content landing page upon selection of the content link by the recipient and identified from the content landing page. The addressability module selects a creative from an advertiser, wherein the creative is targeted to the recipient of the email who is identified by the received identifier, and serves the selected creative for display on the content landing page. | 04-14-2016 |
20160104208 | AD SLOT OWNERSHIP FOR PERSISTENT CREATIVES - An ad slot ownership module receives, from a user agent, a call requesting a creative for a first slot of a plurality of slots in an email and determines whether an ownership period associated with the first slot has expired. When the ownership period associated with the first slot has not expired, the ad slot ownership module selects a creative from a campaign associated with an advertiser that owns the first slot for the ownership period and serves the selected creative for the first slot to the user agent. | 04-14-2016 |
Patent application number | Description | Published |
20150369061 | DOUBLE SNAPPED COVER PLATE FOR ROTOR DISK - According to an exemplary embodiment of this disclosure, among other possible things a gas turbine engine includes a compressor section, a combustor in fluid communication with the compressor section, a turbine section in fluid communication with the combustor section, a plurality of turbine disks in at least one of the compressor section and the turbine sections, at least one cover plate corresponding to at least one of the turbine disks, each of the cover plates includes, at least two snaps connected via a webbing portion, and a bore region radially inward of the at least two snaps and connected to at least one of the at least two snaps via the webbing portion. | 12-24-2015 |
20150377041 | Lock for Retaining Minidisks with Rotors of a Gas Turbine Engine - In accordance with one aspect of the disclosure, a rotor is disclosed. The rotor may include a disk having a central axis, an airfoil radially extending from the disk, a bayonet tab extending radially from the disk, and a lock. The lock may further include a short tab and a long tab, both extending radially from the disk and in an axial direction with respect to the central axis. The long tab may have a greater axial length than the short tab. | 12-31-2015 |
20160003097 | INTERLOCKING ROTOR ASSEMBLY WITH THERMAL SHIELD - A rotor assembly includes a first rotor, a second rotor mounted on the first rotor and co-rotatable there with, and a thermal shield interlocked with the second rotor for co-rotation there with. | 01-07-2016 |
20160069259 | TURBINE MINIDISK BUMPER FOR GAS TURBINE ENGINE - An assembly for a gas turbine engine includes a minidisk that includes an axial extension extending from a disc. The axial extension includes an inner diameter surface and a recess arranged radially opposite the inner diameter surface. The recess provides a radially outwardly extending flange and a bumper extending radially inward from and proud of the inner diameter surface. A method of working on a gas turbine engine section includes inserting a tool into a cavity beneath a seal assembly, and engaging a flange of a minidisk with the tool to manipulate first and second rotors with respect to one another. | 03-10-2016 |
Patent application number | Description | Published |
20110185432 | Cyber Attack Analysis - In certain embodiments, analyzing cyber attacks includes receiving cyber attack parameters. A cyber attack parameter describes a performance attribute of a cyber attack scenario. The cyber attack parameters comprises at least one temporal parameter describing a temporal feature of the cyber attack scenario. The following is performed for each cyber defense of one or more cyber defenses to yield one or more sets of cyber attack metrics: simulating the cyber attack operating with a cyber defense; and determining a set of cyber attack metrics describing the cyber attack operating with the cyber defense. The cyber defenses are evaluated in accordance with the sets of cyber attack metrics. | 07-28-2011 |
20110288904 | System, Method, and Software for Analyzing Maneuvers of an Application in a Distributed Computing Environment - In certain embodiments, an application maneuvering analysis tool accesses application characteristics information indicating one or more characteristics of an application for which a maneuver evaluation is desired. Using the accessed application characteristics information, the application maneuvering analysis tool determines a maneuverability index representing a maneuvering efficiency of the application and determines an implementation difficulty level according to the determined maneuverability index. | 11-24-2011 |
20120101969 | ASSIGNING SENSORS TO PATHS - According to certain embodiments, paths are identified from path data. One or more sensors are assigned to each path. The following are performed: at least one sensor is moved to a path intersection and excess sensors are removed. An excess sensor is a sensor that is not required to satisfy the desired number of sensors of one or more paths. According to certain embodiments, a combined array comprising combined entries is accessed. Each combined entry represents a location and has a value indicating a number of paths at the location. The following are performed to yield a sensor arrangement: a maximum value of the combined array is identified, a sensor is assigned to a location associated with the maximum value, and the paths are removed from the combined array. A result associated with the sensor arrangement is reported. | 04-26-2012 |
20120253664 | Path Determination Using Elevation Data - In certain embodiments, path determination includes receiving terrain elevation data comprising elevation values for locations of an area, where each elevation value indicates an elevation at a location. One or more gradient matrices are calculated from the elevation values. Each gradient matrix comprises gradient values corresponding to the locations. Traversable segments are determined from the gradient matrices, and a path is determined from the traversable segments. | 10-04-2012 |
20120253669 | Maritime Path Determination - In certain embodiments, determining maritime paths includes accessing a feasibility matrix comprising feasibility values for locations of an area. A feasibility value indicates navigability at a location. One or more non-navigable locations represent one or more barriers. Waypoints around the barriers are determined. A cost matrix comprising cost values is calculated. A cost value indicates a distance between two points of a set of points, where the set of points comprises one or more start points, one or more end points, and the waypoints. Dijkstra's technique is applied to a selected start point and a selected end point to yield a shortest length path between the selected start point and the selected end point. | 10-04-2012 |
Patent application number | Description | Published |
20090216563 | ELECTRONIC PROFILE DEVELOPMENT, STORAGE, USE AND SYSTEMS FOR TAKING ACTION BASED THEREON - Examples of the present invention include profiling systems that store, manage and respond to electronic profiles. The profiling systems utilize attributes of the electronic profiles to take predictive or deterministic action, including identifying content to be provided and notification of selected content. Embodiments of the invention allow the profiling system to be used as a trusted intermediary where the profile owning entity controls access to their electronic profiles across their network of devices and services. | 08-27-2009 |
20090216639 | ADVERTISING SELECTION AND DISPLAY BASED ON ELECTRONIC PROFILE INFORMATION - Examples of the present invention include advertising selection and display systems that utilize electronic profiles and information received about one or more network accessible content items an entity accessed, such as a web page. The information and electronic profile is used to determine links, advertisements, or both, that may be displayed in a web browser or other viewer along with the accessed network content. | 08-27-2009 |
20090216696 | DETERMINING RELEVANT INFORMATION FOR DOMAINS OF INTEREST - Techniques are described for determining and using relevant information related to domains of interest. In at least some situations, the techniques include automatically analyzing documents, terms and other information related to a domain of interest in order to automatically determine information about relevant themes within the domain and/or about which documents have contents that are relevant to such themes. Such automatically determined information related to a domain may then be used in various ways, including to assist users in specifying themes of interest and/or in obtaining documents and/or document fragments with contents that are relevant to specified themes. In addition, information about how the automatically determined information is used by users may be tracked and used as feedback for learning improved determinations of relevant themes and relevant documents within the domain, such as by using automated machine learning techniques. | 08-27-2009 |
20090216750 | ELECTRONIC PROFILE DEVELOPMENT, STORAGE, USE, AND SYSTEMS THEREFOR - Examples of the present invention include profiling systems that store, manage, and utilize profile information to take predictive or deterministic action. Embodiments of the invention allow the profiling system to be used as a trusted intermediary where the profile owning entity controls access to their profile information across their network of devices and services. | 08-27-2009 |
20100023952 | PLATFORM FOR DATA AGGREGATION, COMMUNICATION, RULE EVALUATION, AND COMBINATIONS THEREOF, USING TEMPLATED AUTO-GENERATION - Embodiments of the present invention provide platforms for data aggregation, communication, rule evaluation, and combinations thereof. The platform may include three distinct functional layers; a core layer, an adaptive layer and an intelligence layer. Furthermore, the platform may include a data block, messaging block, rule block, or combinations thereof. Generally, the platform may facilitate data acquisition, storage, and manipulation between and among clients and data sources in a generic manner. That is, clients may communicate and make requests independent of a target system or database type. The platform may process the communications and requests in a manner suitable to the target system or database type. The platform may also evaluate rules received from the clients in a manner generic to the client application. Instances of the platform for a given application may be efficiently created using a template-based mechanism. In this manner, the platform may be used to support a variety of end user applications in a flexible, scalable manner. | 01-28-2010 |
20100153324 | PROVIDING RECOMMENDATIONS USING INFORMATION DETERMINED FOR DOMAINS OF INTEREST - Techniques are described for determining and using information related to domains of interest, such as by automatically analyzing documents and other information related to a domain in order to automatically determine relationships between particular terms within the domain. Such automatically determined information may then be used to assist users in obtaining information from the domain that is of interest (e.g., documents with contents that are relevant to user-specified terms and/or to other terms that are determined to be sufficiently related to the user-specified terms). For example, recommendations may be automatically generated for a user by using information about specified preferences or other interests of the user with respect to one or more terms and identifying other particular terms that are sufficiently probable to be of interest to that user, such as based on a generated probabilistic representation of relationships between particular terms for the domain. | 06-17-2010 |
20110276563 | SYSTEMS, METHODS, AND COMPUTER READABLE MEDIA FOR SECURITY IN PROFILE UTILIZING SYSTEMS - Security and distributed storage is described for systems using electronic profile information. Embodiments may be utilized for ID, data, and access analysis. Dynamic distributed redundant encryption may be used that may be based on user, device, location, context information, physical, or environmental characteristics. | 11-10-2011 |
20130066887 | DETERMINING RELEVANT INFORMATION FOR DOMAINS OF INTEREST - Techniques are described for determining and using relevant information related to domains of interest. In at least some situations, the techniques include automatically analyzing documents, terms and other information related to a domain of interest in order to automatically determine information about relevant themes within the domain and/or about which documents have contents that are relevant to such themes. Such automatically determined information related to a domain may then be used in various ways, including to assist users in specifying themes of interest and/or in obtaining documents and/or document fragments with contents that are relevant to specified themes. In addition, information about how the automatically determined information is used by users may be tracked and used as feedback for learning improved determinations of relevant themes and relevant documents within the domain, such as by using automated machine learning techniques. | 03-14-2013 |
20130138512 | ELECTRONIC PROFILE DEVELOPMENT, STORAGE, USE, AND SYSTEMS THEREFOR - Examples of the present invention include profiling systems that store, manage, and utilize profile information to take predictive or deterministic action. Embodiments of the invention allow the profiling system to be used as a trusted intermediary where the profile owning entity controls access to their profile information across their network of devices and services. | 05-30-2013 |
20130151570 | PLATFORM FOR DATA AGGREGATION, COMMUNICATION, RULE EVALUATION, AND COMBINATIONS THEREOF, USING TEMPLATED AUTO-GENERATION - Platforms for data aggregation, communication, rule evaluation, and combinations thereof are described. The platform may include three distinct functional layers; a core layer, an adaptive layer and an intelligence layer. Furthermore, the platform may include a data block, messaging block, rule block, or combinations thereof. Generally, the platform may facilitate data acquisition, storage, and manipulation between and among clients and data sources in a generic manner. That is, clients may communicate and make requests independent of a target system or database type. The platform may process the communications and requests in a manner suitable to the target system or database type. The platform may also evaluate rules received from the clients in a manner generic to the client application. Instances of the platform for a given application may be efficiently created using a template-based mechanism, for example for supporting a variety of end user applications in a flexible, scalable manner. | 06-13-2013 |
20130325769 | PROVIDING RECOMMENDATIONS USING INFORMATION DETERMINED FOR DOMAINS OF INTEREST - Techniques are described for determining and using information related to domains of interest, such as by automatically analyzing documents and other information related to a domain in order to automatically determine relationships between particular terms within the domain. Such automatically determined information may then be used to assist users in obtaining information from the domain that is of interest (e.g., documents with contents that are relevant to user-specified terms and/or to other terms that are determined to be sufficiently related to the user-specified terms). For example, recommendations may be automatically generated for a user by using information about specified preferences or other interests of the user with respect to one or more terms and identifying other particular terms that are sufficiently probable to be of interest to that user, such as based on a generated probabilistic representation of relationships between particular terms for the domain. | 12-05-2013 |
Patent application number | Description | Published |
20140108047 | Methods and systems for medical auto-coding using multiple agents with automatic adjustment - This disclosure is directed to methods and automated documentation and medical-coding systems that combine predictions of clinical decision support or multiple medical-code assignments into a final medical-code assignment, such that the combination is different for different contexts. In certain implementations, each agent receives the same set of terms and phrases extracted from an electronic medical record (“EMR”). Based on the context of the EMR, each agent extracts medical codes from one or more medical codebooks, compares the terms and phrases to the medical codes, and assigns a code to the EMR based on a confidence score. The multiple code assignments are combined to generate a final medical-code assignment based on the confidence scores, context, and each agent's historical performance within the context. The automated system stores and outputs the final medical-code assignment. | 04-17-2014 |
20140250377 | METHOD AND SYSTEM FOR SEARCHING AND ANALYZING LARGE NUMBERS OF ELECTRONIC DOCUMENTS - The current document is directed to methods and systems for accessing, searching, analyzing, and visualizing electronically stored information, including electronic documents. These methods and systems construct graph-like representations of information searches that can be visualized and manipulated in three dimensions. The three-dimensional rendering of search results allows for very large numbers of search results to be visualized conveniently using a graphical user interface displayed on an electronic display device. Methods and systems provide for three-dimensional manipulation of graph-like renderings of search results, visualization-assisted searching, and a large number of research tools for discovering and storing various types of links, connections, and relationships between electronically stored information entities. | 09-04-2014 |
20140372956 | METHOD AND SYSTEM FOR SEARCHING AND ANALYZING LARGE NUMBERS OF ELECTRONIC DOCUMENTS - The current document is directed to methods and systems for accessing, searching, analyzing, and visualizing electronically stored information, including electronic documents. These methods and systems construct graph-like representations of information searches that can be visualized and manipulated in three dimensions. The three-dimensional rendering of search results allows for very large numbers of search results to be visualized conveniently using a graphical user interface displayed on an electronic display device. Methods and systems provide for three-dimensional manipulation of graph-like renderings of search results, visualization-assisted searching, and a large number of research tools for discovering and storing various types of links, connections, and relationships between electronically stored information entities. | 12-18-2014 |
20150039344 | AUTOMATIC GENERATION OF EVALUATION AND MANAGEMENT MEDICAL CODES - The current document is directed to methods and systems for automated generation of evaluation and management medical codes (“E/M codes”). In one implementation, a series of processes are applied to a medical document in order to generate annotations and concepts, extract metadata, and, using the annotations and concepts, and, in certain cases, the extracted metadata, to generate a set of feature/feature-value pairs that parametrically represent the contents of the medical document. Models for E/M codes and E/M-code components are generated to contain sets of weights, each weight corresponding to a feature for which a feature-value is automatically generated from medical documents. These weights are used as multipliers, in certain implementations, of the feature values generated for a medical document. Multiplication of feature values by corresponding weights produces terms that are used to generate scores for each of various different E/M codes. The generated scores provide a basis for selecting one or more E/M codes for the medical document. | 02-05-2015 |
20150046182 | METHODS AND AUTOMATED SYSTEMS THAT ASSIGN MEDICAL CODES TO ELECTRONIC MEDICAL RECORDS - The current document is directed to methods and automated systems that assign individual medical codes selected from one or more medical codebooks to electronic medical records. In certain implementations, the currently disclosed automated systems generate multiple streams of medical terms or medical terms and phrases from an electronic medical record as well as multiple streams of medical terms or medical terms and phrases from individual medical codes contained within a medical codebook and then use stream-comparison functionality to select those individual medical codes of the medical codebook most likely to be relevant and related to the information encoded within the electronic medical record. In addition, in a disclosed implementation, the automated medical-coding system includes comprehensive training and feedback components that allow the automated medical-coding system to be trained and to continuously improve, over time, the accuracy, precision, and reliability of the assignment of medical codes to electronic medical records. | 02-12-2015 |
20150178052 | AUTOMATED EXPERIMENTATION PLATFORM - The present document is directed to an automated experimentation platform that provides a visual integrated development environment (“IDE”) that allows a user to construct and execute various types of data-driven workflows. The automated experimentation platform includes back-end components that include API servers, a catalog, a cluster-management component, and execution-cluster nodes. Workflows are visually represents as directed acyclic graphs and texturally encoded. The workflows are transformed into jobs that are distributed for execution to the execution-cluster nodes. | 06-25-2015 |
20150269335 | METHOD AND SYSTEM FOR ESTIMATING VALUES DERIVED FROM LARGE DATA SETS BASED ON VALUES CALCULATED FROM SMALLER DATA SETS - The current document is directed to methods and systems for estimating values that could be derived from a large data set, were it available, from values computed from an available smaller data set. A specific example of the currently described methods and systems are methods and systems that estimate various medical-record-related statistics and values computed from hypothetical datasets. In order to extrapolate the desired statistics and computed values from the observed smaller data set, multiple models are employed by the currently disclosed methods and systems. These models can be employed sequentially to generate relatively fine-grained estimates over various multi-dimensional data-set volumes. | 09-24-2015 |
20160063187 | AUTOMATED SYSTEM FOR HANDLING FILES CONTAINING PROTECTED HEALTH INFORMATION - The current document is directed to methods and automated systems for handling files and other data during a data ingestion process that may contain PHI within the file content, filenames, file-associated metadata, and other such data-associated information. The methods and automated systems protect sensitive health information using encryption methods to prevent the protected health information from being exposed. In certain implementations, the currently disclosed automated system includes a client-network system, one or more client servers, an encrypted data-storage device including a source folder for temporarily storing original files downloaded from the client network system and a second folder for storing PHI-free files created from the original files, and processes that create the PHI-free files from the original files, remove the original files from the source folder, and securely copy the PHI-free files to a secure file-transfer protocol server to be processed for later use. | 03-03-2016 |
Patent application number | Description | Published |
20150370228 | DETERMINING CONTROL ACTIONS OF DECISION MODULES - Techniques are described for implementing automated control systems that manipulate operations of specified target systems, such as by modifying or otherwise manipulating inputs or other control elements of the target system that affect its operation (e.g., affect output of the target system). An automated control system may have one or more decision modules that each controls at least some of a target system, with each decision module's control actions being automatically determined to reflect near-optimal solutions with respect to or one more goals and in light of a target system model having multiple inter-related constraints, such as based on a partially optimized solution that is within a threshold amount of a fully optimized solution. Such determination of one or more control actions to perform may occur for a particular time and particular decision module, as well as be repeated over multiple times for ongoing control. | 12-24-2015 |
20150370232 | MANAGING COORDINATED CONTROL BY MULTIPLE DECISION MODULES - Techniques are described for implementing automated control systems that manipulate operations of specified target systems, such as by modifying or otherwise manipulating inputs or other control elements of the target system that affect its operation (e.g., affect output of the target system). An automated control system may in some situations have a distributed architecture with multiple decision modules that each controls a portion of a target system and operate in a partially decoupled manner with respect to each other, such as by each decision module operating to synchronize its local solutions and proposed control actions with those of one or more other decision modules, in order to determine a consensus with those other decision modules. Such inter-module synchronizations may occur repeatedly to determine one or more control actions for each decision module at a particular time, as well as to be repeated over multiple times for ongoing control. | 12-24-2015 |
20160004228 | COOPERATIVE DISTRIBUTED CONTROL OF TARGET SYSTEMS - Techniques are described for implementing automated control systems that manipulate operations of specified target systems, such as by modifying or otherwise manipulating inputs or other control elements of the target system that affect its operation (e.g., affect one or more outputs of the target system). An automated control system for such a target system may in some situations have a distributed architecture that provides cooperative distributed control of the target system, such as with multiple decision modules that each control a portion of the target system and operate in a partially decoupled manner with respect to each other, with the various decision modules' operations being at least partially synchronized and each having a consensus with one or more other decision modules, even if a fully synchronized convergence of all decision modules at all times is not guaranteed. | 01-07-2016 |
Patent application number | Description | Published |
20080273372 | Method of Programming Multi-Layer Chalcogenide Devices - A method of programming a multi-layer chalcogenide electronic device. The device includes an active region in electrical communication with two terminals, where the active region includes two or more layers. The method includes providing an electrical signal between the two terminals, where the electrical signal alters an electrical characteristic of a layer remote from one of the terminals. In one embodiment, the layer remote from the terminal is a chalcogenide material and the electrical characteristic is resistance. In another embodiment, an electrical characteristic of the layer in contact with the terminal is also altered. The alteration of an electrical characteristic may be caused by a transformation of a chalcogenide material from one structural state to another structural state. | 11-06-2008 |
20090140229 | Active material devices with containment layer - An active material electronic device is described with a containment layer. The device includes an active chalcogenide, pnictide, or phase-change material in electrical communication with an upper and lower electrode. The device includes a containment layer formed over the active material that prevents escape of volatilized matter from the active material when the device is exposed to high temperatures during fabrication or operation. The containment layer further prevents chemical contamination of the active material by protecting it from reactive species in the processing or ambient environment. The containment layer and intermediate layers formed between the active material and containment layer are formed at temperatures sufficiently low to prevent volatilization of the active material. Once the containment layer is formed, the device may be subjected to high temperature or chemically aggressive environments without impairing the compositional or structural integrity of the active material. Inclusion of the containment layer is shown to extend the cycle life of the device by over two orders of magnitude. | 06-04-2009 |
20090298222 | Method for manufacturing Chalcogenide devices - A method of chalcogenide device formation includes treatment of the surface upon which the chalcogenide material is deposited. The treatment reduces or eliminates native oxides and other contaminants from the surface, thereby increasing the adhesion of the chalcogenide layer to the treated surface, eliminating voids between the chalcogenide layer and deposition surface and reducing the degradation of chalcogenide material due to the migration of contaminants into the chalcogenide. | 12-03-2009 |
20100221868 | Active Material Devices with Containment Layer - An active material electronic device is described with a containment layer. The device includes an active chalcogenide, pnictide, or phase-change material in electrical communication with an upper and lower electrode. The device includes a containment layer formed over the active material that prevents escape of volatilized matter from the active material when the device is exposed to high temperatures during fabrication or operation. The containment layer further prevents chemical contamination of the active material by protecting it from reactive species in the processing or ambient environment. The containment layer and intermediate layers formed between the active material and containment layer are formed at temperatures sufficiently low to prevent volatilization of the active material. Once the containment layer is formed, the device may be subjected to high temperature or chemically aggressive environments without impairing the compositional or structural integrity of the active material. Inclusion of the containment layer is shown to extend the cycle life of the device by over two orders of magnitude. | 09-02-2010 |
20100221896 | Electrical Device with Improved Electrode Surface - An electronic device having a reduced-roughness electrode surface. The device includes an active material that forms an interface with a treated electrode surface. Treatment of the electrode surface reduces the roughness of the surface to promote adhesion, conformality, and/or electrical contact of the active material to the electrode. The reduced-roughness electrode surface facilitates the formation of a regular, uniform interface with the active material and minimizes the formation of interfacial voids and/or localized contact points that compromise device performance or endurance. Active materials include variable resistance materials and electrical switching materials. | 09-02-2010 |
20100283029 | Programmable resistance memory and method of making same - A memory includes multiple layers of deposited memory material. An etch is performed on at least one layer of deposited memory material prior to the deposition of a subsequent layer of memory material. | 11-11-2010 |
Patent application number | Description | Published |
20090285761 | Renal Function Analysis Method and Apparatus - A method for measuring a glomerular filtration rate in a mammalian kidney comprises a source of reporter and marker fluorescent molecules. The fluorescent molecules are introduced into the blood stream of a mammalian subject. Over a period of time, a measurement of the intensities of the reporter and marker fluorescent molecules is taken. A ratio is calculated to determine the health of the subject's kidney. This method measures volume of plasma distribution based on a fluorescence of a marker molecule relative to a fluorescence of a reporter molecule. | 11-19-2009 |
20110201940 | Renal Function Analysis Method and Apparatus - A method for measuring a glomerular filtration rate of a mammalian subject comprises a source of reporter and marker fluorescent molecules. The fluorescent molecules are introduced into the vascular system of the mammalian subject. Over a period of time, a measurement of the intensities of the reporter and marker fluorescent molecules is taken. A ratio is calculated to determine the glomerular filtration rate. | 08-18-2011 |
20130116518 | RENAL FUNCTION ANALYSIS METHOD AND APPARATUS - A method for measuring a glomerular filtration rate in a mammalian kidney comprises a source of reporter and marker fluorescent molecules. The fluorescent molecules are introduced into the blood stream of a mammalian subject. Over a period of time, a measurement of the intensities of the reporter and marker fluorescent molecules is taken. A ratio is calculated to determine the health of the subject's kidney. This method measures volume of plasma distribution based on a fluorescence of a marker molecule relative to a fluorescence of a reporter molecule. | 05-09-2013 |
20140050667 | RENAL FUNCTION ANALYSIS METHOD AND APPARATUS - A method for measuring a glomerular filtration rate in a mammalian kidney comprises a source of reporter and marker fluorescent molecules. The fluorescent molecules are introduced into the blood stream of a mammalian subject. Over a period of time, a measurement of the intensities of the reporter and marker fluorescent molecules is taken. A ratio is calculated to determine the health of the subject's kidney. This method measures volume of plasma distribution based on a fluorescence of a marker molecule relative to a fluorescence of a reporter molecule. | 02-20-2014 |
20140369936 | COMPOSITIONS AND METHODS FOR MONITORING BIOMETRIC INDICATORS - Methods of measurement of biometric indicators in a mammalian subject are described. Biometric indicators of interest include hematocrit, plasma volume, volume of distribution, and glomerular filtration rate. The methods are especially applicable to subjects with rapid blood loss and to subjects with unstable hematocrits. Hematocrit may be measured by administering an injectate with a dynamic fluorescent marker and a static fluorescent marker, or a single static marker with two fluorescent tags, into the vascular system of the subject, and monitoring the emission intensities of the markers or fluorescent tags over a period of time. Hematocrit may then be calculated using a calibrated spectrometric analyzer by determining the raw ratio of the markers at T0, calculating the apparent hematocrit, and applying a correction factor. | 12-18-2014 |
Patent application number | Description | Published |
20100204171 | MATERIALS AND METHODS FOR TREATING DISEASES CAUSED BY GENETIC DISORDERS USING AMINOGLYCOSIDES AND DERIVATIVES THEREOF WHICH EXHIBIT LOW NEPHROTOXICITY - Various aspects related to the preparation of congeners of the aminoglycosides gentamicin such as the congener C2 and using this compound or derivatives thereof and pharmaceutically active salts to treat diseases that involve genetic mutations which introduce a missense or premature stop codon into a gene. Still other aspects include treating human or animal patients with the gentamicin congener C2 and derivatives and pharmaceutical salt thereof to overcome, or to at least mitigate, the symptoms of disease and disorders such as some forms of Becker's or Duchenne muscular dystrophy, Hurler's Syndrome and Cystic Fibrosis that have as their etiology the presence of a premature stop codon in a gene whose proper expression is necessary for good health. | 08-12-2010 |
20120157398 | MATERIALS AND METHODS FOR TREATING DISEASES CAUSED BY GENETIC DISORDERS USING AMINOGLYCOSIDES AND DERIVATIVES THEREOF WHICH EXHIBIT LOW NEPHROTOXICITY - Various aspects related to the preparation of congeners of the aminoglycosides gentamicin such as the congener C2 and using this compound or derivatives thereof and pharmaceutically active salts to treat diseases that involve genetic mutations which introduce a missense or premature stop codon into a gene. Still other aspects include treating human or animal patients with the gentamicin congener C2 and derivatives and pharmaceutical salt thereof to overcome, or to at least mitigate, the symptoms of disease and disorders such as some forms of Becker's or Duchenne muscular dystrophy, Hurler's Syndrome and Cystic Fibrosis that have as their etiology the presence of a premature stop codon in a gene whose proper expression is necessary for good health. | 06-21-2012 |
20120276014 | MEASUREMENT OF BODY FLUID VOLUMES - The present invention is related generally to measurement of body fluid volumes in an animal subject. The body fluid volumes of interest include extracellular fluid volume (ECFV), total vascular plasma volume (TVPV) and interstitial fluid volume (IFV). The methods are especially beneficial for subjects suffering from renal failure and particularly those undergoing renal dialysis. ECFV can be measured by administering a first molecule which is non-metabolized and permeable to vessel walls of the vascular system wherein the first molecule is distributed within the total vascular space as well as the interstitial space. TVPV can be measured by administering a second molecule which is non-metabolized and impermeable to vessel walls of the vascular system wherein the second molecule is distributed within only the vascular space. IFV can then be calculated using the equation IFV=ECFV−TVPV. | 11-01-2012 |
20130101518 | METHOD AND APPARATUS FOR KIDNEY FUNCTION ANALYSIS - A method and apparatus for determining physiological data related to an animal, such as kidney diagnostics data, is provided. The method includes injecting a mixture of a first and a second molecule into an animal (e.g., a human patient), determining a molecular ratio of the molecules, and determining the physiological data based on the molecular ratio. The apparatus includes a number of finger receiving apertures, a light generation circuit, a light detection circuit, a pulse counting circuit, and a user interface. | 04-25-2013 |
20150182545 | MATERIALS AND METHODS FOR TREATING DISEASES CAUSED BY GENETIC DISORDERS USING AMINOGLYCOSIDES AND DERIVATIVES THEREOF WHICH EXHIBIT LOW NEPHROTOXICITY - Various aspects related to the preparation of congeners of the aminoglycosides gentamicin such as the congener C2 and using this compound or derivatives thereof and pharmaceutically active salts to treat diseases that involve genetic mutations which introduce a missense or premature stop codon into a gene. Still other aspects include treating human or animal patients with the gentamicin congener C2 and derivatives and pharmaceutical salt thereof to overcome, or to at least mitigate, the symptoms of disease and disorders such as some forms of Becker's or Duchenne muscular dystrophy, Hurler's Syndrome and Cystic Fibrosis that have as their etiology the presence of a premature stop codon in a gene whose proper expression is necessary for good health. | 07-02-2015 |
Patent application number | Description | Published |
20130102780 | TRANSITION METAL-CATALYZED PROCESSES FOR THE PREPARATION OF N-ALLYL COMPOUNDS AND USE THEREOF - The present disclosure provides processes for the N-dealkylation of tertiary amines and the use of transition metal catalysts to prepare tertiary N-allyl amine derivatives and secondary amine derivatives thereof. The tertiary amines can be alkaloids and, more particularly, the tertiary amines can be opioids. In specific embodiments, the present disclosure provides methods for use in processes for the synthesis of naloxone and naltrexone from oripavine. | 04-25-2013 |
20130102784 | PROCESS FOR N-DEALKYLATION OF TERTIARY AMINES - The present disclosure provides improved methods for N-dealkylation of tertiary amines, including methods for N-demethylation of alkaloids and opioids, in which the dealkylation reaction is carried out in a solvent comprising a tertiary alcohol. The present disclosure also provides improved processes for preparing semi-synthetic opioids that incorporate the disclosed methods for N-dealkylation of tertiary amines. | 04-25-2013 |
20150087839 | PROCESS FOR N-DEALKYLATION OF TERTIARY AMINES - The present disclosure provides improved methods for N-dealkylation of tertiary amines, including methods for N-demethylation of alkaloids and opioids, in which the dealkylation reaction is carried out in a solvent comprising a tertiary alcohol. The present disclosure also provides improved processes for preparing semi-synthetic opioids that incorporate the disclosed methods for N-dealkylation of tertiary amines. | 03-26-2015 |
20150336972 | TRANSITION METAL-CATALYZED PROCESSES FOR THE PREPARATION OF N-ALLYL COMPOUNDS AND USE THEREOF - The present disclosure provides processes for the N-dealkylation of tertiary amines and the use of transition metal catalysts to prepare tertiary N-allyl amine derivatives and secondary amine derivatives thereof. The tertiary amines can be alkaloids and, more particularly, the tertiary amines can be opioids. In specific embodiments, the present disclosure provides methods for use in processes for the synthesis of naloxone and naltrexone from oripavine. | 11-26-2015 |
20150353567 | TRANSITION METAL-CATALYZED PROCESSES FOR THE PREPARATION OF N-ALLYL COMPOUNDS AND USE THEREOF - The present disclosure provides processes for the N-dealkylation of tertiary amines and the use of transition metal catalysts to prepare tertiary N-allyl amine derivatives and secondary amine derivatives thereof. The tertiary amines can be alkaloids and, more particularly, the tertiary amines can be opioids. In specific embodiments, the present disclosure provides methods for use in processes for the synthesis of naloxone and naltrexone from oripavine. | 12-10-2015 |
20150353568 | TRANSITION METAL-CATALYZED PROCESSES FOR THE PREPARATION OF N-ALLYL COMPOUNDS AND USE THEREOF - The present disclosure provides processes for the N-dealkylation of tertiary amines and the use of transition metal catalysts to prepare tertiary N-allyl amine derivatives and secondary amine derivatives thereof. The tertiary amines can be alkaloids and, more particularly, the tertiary amines can be opioids. In specific embodiments, the present disclosure provides methods for use in processes for the synthesis of naloxone and naltrexone from oripavine. | 12-10-2015 |
20150353569 | TRANSITION METAL-CATALYZED PROCESSES FOR THE PREPARATION OF N-ALLYL COMPOUNDS AND USE THEREOF - The present disclosure provides processes for the N-dealkylation of tertiary amines and the use of transition metal catalysts to prepare tertiary N-allyl amine derivatives and secondary amine derivatives thereof. The tertiary amines can be alkaloids and, more particularly, the tertiary amines can be opioids. In specific embodiments, the present disclosure provides methods for use in processes for the synthesis of naloxone and naltrexone from oripavine. | 12-10-2015 |