Inventors list

Assignees list

Classification tree browser

Top 100 Inventors

Top 100 Assignees


Samuels, US

Allen Samuels, Ann Arbor, MI US

Patent application numberDescriptionPublished
20080263757HYGIENE STATION FOR INDIVIDUALS - The present invention comprises a disposable hygiene device with a toilet seat with a top and bottom surfaces, where the toilet seat folds for storage before or after use. A receptacle is attached to the bottom surface of the toilet seat. After use, an adhesive on the top surface of the toilet seat is exposed by the removal of a protective layer. The toilet seat may then be folded onto itself to seal the hygiene device for easy disposal. The toilet seat may also include handles or an extension to ease proper orientation and use of the disposable hygiene device. The present invention also includes hygiene stations, preferably portable, that may be used with the disposable hygiene device, hygiene stations that include rotatable, extendable and height adjustable bathroom fixtures, and hygiene stations have a common connection point for inputs and outputs.10-30-2008

Bruce P. Samuels, Shoreline, WA US

Patent application numberDescriptionPublished
20110304479Perspective Runway System - A method, apparatus, and computer program product for displaying information about runways. A runway for an aircraft is identified when the aircraft is within a selected distance of the runway. A number of graphical indicators are displayed on a display in a flight deck. The number of graphical indicators corresponds to a number of features of the runway present in a field of view for an eye reference point in the flight deck.12-15-2011

Christopher Samuels, Glendale, CA US

Patent application numberDescriptionPublished
20100048089Collectible marble set - Described is a collectible marble set where the marble enhancements are tied to a media. The collectible marble set includes a plurality of marbles, the plurality of marbles having at least a first set of marbles and a second set of marbles. Each of the marbles have an insert therein, wherein the first set of marbles has an insert with a first color and the second set of marbles has an insert with a second color. The plurality of marbles are formed to be tied to a media having a first character set and a second character set, such that the first color represents the first character set and the second color represents the second character set.02-25-2010

Corey L. Samuels, Seattle, WA US

Patent application numberDescriptionPublished
20080288328CONTENT ADVERTISING PERFORMANCE OPTIMIZATION SYSTEM AND METHOD - A content targeted advertising performance optimization system and method are provided herein.11-20-2008

Donald J. Samuels, Silverthorne, CO US

Patent application numberDescriptionPublished
20090037866ALTERNATING PHASE SHIFT MASK OPTIMIZATION FOR IMPROVED PROCESS WINDOW - A method for designing alternating phase shift masks is provided, in which narrow phase shapes located between densely spaced design shapes are colored to allow a maximum amount of light transmission. After assigning and ensuring binary legalization of the phase shapes, the narrow phase shapes are assigned a color, such as 0° phase shift, that allows the more light transmission than the alternate or opposite color (e.g. 180° phase shift), which helps avoid printing errors such as resist scumming between closely spaced shapes, and maximizes the lithographic process window.02-05-2009
20090065956MEMORY CELL - Methods of forming line ends and a related memory cell including the line ends are disclosed. In one embodiment, the memory cell includes fa first device having a first conductive line extending over a first active region and having a first line end of the first conductive line positioned over an isolation region adjacent to the first active region; and a second device having a second conductive line extending over one of a second active region and a contact element and having a second line end of the second conductive line positioned over the isolation region adjacent to the one of the second active region and the contact element, wherein the first line end and the second line end each include a bulbous end that is distanced from a respective active region or contact element.03-12-2009
20090068837LINE ENDS FORMING - Methods of forming line ends and a related memory cell including the line ends are disclosed. In one embodiment, the method includes forming a first device element and a second device element separated from the first device element by a space; and forming a first line extending from the first device element, the first line including a bulbous line end over the space and distanced from the first device element, and a second line extending from the second device element, the second line including a bulbous line end over the space and distanced from the second device element.03-12-2009
20090117737POLYCONDUCTOR LINE END FORMATION AND RELATED MASK - Methods of forming adjacent polyconductor line ends and a mask therefor are disclosed. In one embodiment, the method includes forming a polyconductor layer over an isolation region; forming a mask over the polyconductor layer, the mask including shapes to create the polyconductor line ends and a correction element to ensure a designed proximity of the polyconductor line ends; and etching the polyconductor layer using the patterned photoresist mask to create the adjacent polyconductor line ends, wherein the correction element is removed during the etching.05-07-2009
20110289470Methods and Systems to Meet Technology Pattern Density Requirements of Semiconductor Fabrication Processes - Techniques, systems, and methods are provided for optimizing pattern density fill patterns for integrated circuits. The method includes adjusting an area of a scribe line and a density of dummy fill shapes in the adjusted scribe line, while maintaining an area of the die, to achieve a pattern density associated with technology ground rules for a particular design of the die.11-24-2011

Patent applications by Donald J. Samuels, Silverthorne, CO US

Douglas E. Samuels, Pound Ridge, NY US

Patent application numberDescriptionPublished
20090276154METHOD AND SYSTEM FOR COORDINATING GROUP TRAVEL AMONG MOBILE DEVICES - An approach is provided for coordinating travel. A plurality of mobile devices is identified as a group, wherein each of the mobile devices is configured to obtain location information. A lead mobile device is designated among the group. Routing information or information about a common destination, specified by the lead mobile device, is transmitted to other mobile devices in the group.11-05-2009

George J. Samuels, Williamsville, NY US

Patent application numberDescriptionPublished
20090283712SESQUITERPENE STABILIZED COMPOSITIONS - Provided is a composition comprising (a) at least one halogenated compound selected from the group consisting of C11-19-2009
20100081570HERBICIDE COMPOSITIONS - Chloropentafluoropropene is employed as a herbicide for the effective control of undesirable spermatophyte growth.04-01-2010
20110126558USE OF LOW GWP REFRIGERANTS COMPRISING CF3I WITH STABLE LUBRICANTS - The invention pertains to heat transfer compositions, particularly to automobile refrigerants comprising a hydrofluoroalkene, an iodocarbon, and at least one lubricant having hydrogen atoms and carbon atoms, wherein no more than 17% of the total number of hydrogen atoms which are attached to a carbon atom are tertiary hydrogen atoms.06-02-2011

Patent applications by George J. Samuels, Williamsville, NY US

Herbert Samuels, New Rochelle, NY US

Patent application numberDescriptionPublished
20100317594Methods for treating breast cancer using NRIF3 related molecules - Disclosed herein is the discovery that administration of the NRIF3 family of transcriptional coregulators (NRIF3 and related molecules) to breast cancer cells induce rapid and profound apoptosis (nearly 100% cell death within 24 h). A novel death domain (DD1) was mapped to a short 30 amino acid region common to all members of the NRIF3 family. Two other death domains (DD2 and DD3) were also found to have effective breast cancer killing activities. Mechanistic studies showed that DD1-induced apoptosis occurred through a novel caspase-2 mediated pathway that involved mitochondria membrane permeabilization but did not require other caspases. Interestingly, cytotoxicity of NRIF3 related molecules was cell-type specific, as they selectively killed breast cancer or related cells but not other examined cells of different origins, suggesting the presence in breast cancer cells of a specific death switch that can be selectively triggered by NRIF3 and related molecules. Also disclosed are strategies utilizing NRIF3 related molecules and/or targeting this death switch for the development of novel and more selective therapeutics against breast cancer.12-16-2010

Patent applications by Herbert Samuels, New Rochelle, NY US

Herbert H. Samuels, New Rochelle, NY US

Patent application numberDescriptionPublished
20090286252NRIF3, NOVEL CO-ACTIVATOR FOR NUCLEAR HORMONE RECEPTORS - Nucleic acids encoding NRIF3 are described. Polypeptides having amino acid sequences of NRIF3 proteins are also provided. A method is also provided for isolating and cloning NRIF3 cDNA. NRIF3 is useful in development/implementation of high throughput screens to identify novel thyroid hormone receptor (TR) and retinoid X receptor (RXR) agonists and antagonists. Methods are also provided for identifying compounds that directly interfere with the interaction of NRIF3 and TR or RXR. Finally, therapies based on modulation of NRIF3 activity are disclosed.11-19-2009
20100286182HYDRAZIDE COMPOUNDS AS THYROID HORMONE RECEPTOR MODULATORS AND USES THEREOF - A method of identification of compounds that modulate thyroid hormone activity, and the use of such compounds and compositions thereof for such purposes are disclosed. The compounds may be selected from the group consisting of:11-11-2010

Patent applications by Herbert H. Samuels, New Rochelle, NY US

Howard Samuels, Newton, MA US

Patent application numberDescriptionPublished
20090154910Camera with Acceleration Sensor - A method and system for determining camera positioning information from an accelerometer mounted on a camera. The accelerometer measures the orientation of the camera with respect to gravity. Orientation measurement allows user interface information to be displayed in a “right side up” orientation on a viewfinder for any camera orientation. Alternatively, an artificial horizon indicator may be displayed in the viewfinder. The accelerometer may also measure camera movement. Camera movement information together with camera orientation can be used to determine camera usage. Additionally, camera movement information can be used to determine a minimum shutter speed for a sharp picture.06-18-2009
20090235717Sensor Self-Test Transfer Standard - A system, computer program product and method of obtaining a performance parameter associated with a sensor, such as an accelerometer, is provided. The method includes applying an acceleration to the accelerometer and a first frequency to obtain a sensitivity of the accelerometer at the first frequency. A first self-test is performed on the accelerometer. The first self-test includes stimulating the accelerometer with a first self-test stimulation signal encoded with the first frequency, such that the accelerometer outputs a first signal. A self-test equivalent acceleration is then determined based, at least in part, on the first signal and the accelerometer sensitivity at the first frequency. A second self-test is performed on the accelerometer. The second self-test includes stimulating the accelerometer with a second self-test stimulation signal encoded with the second frequency, such that the accelerometer outputs a second signal. A parameter of the accelerometer is determined at the second frequency based, at least in part, on the second signal and the self-test equivalent acceleration. The parameter may be sensitivity of the accelerometer at the second frequency.09-24-2009

Patent applications by Howard Samuels, Newton, MA US

Howard R. Samuels, Newton, MA US

Patent application numberDescriptionPublished
20090309613Anti-Capture Method and Apparatus for Micromachined Devices - A MEMS device has a movable beam, a differential capacitor with a movable electrode that moves in response to the displacement of the movable beam and that is disposed between two stationary electrodes, and a voltage circuit for applying a first voltage to the first stationary electrode, second voltage to the second stationary electrode, and a third voltage to the movable electrode. The MEMS device also has a monitor operably coupled with the movable beam to monitor the displacement of the movable beam. In some embodiments, the monitor may monitor the distance between the movable electrode and at least one of the stationary electrodes. The MEMS device further has a voltage reducing circuit operatively coupled with the monitor, the movable electrode, and the stationary electrodes. The voltage reducing circuit reduces the differential between the third voltage and the voltages on the stationary electrodes when the monitor detects that the displacement of the movable beam is greater than or equal to a threshold value.12-17-2009
20110221454Anti-Capture Method and Apparatus for Micromachined Devices - A MEMS device has a movable beam, a differential capacitor with a movable electrode that moves in response to the displacement of the movable beam and that is disposed between two stationary electrodes, and a voltage circuit for applying a first voltage to the first stationary electrode, second voltage to the second stationary electrode, and a third voltage to the moveable electrode. The MEMS device also has a monitor operably coupled with the movable beam to monitor the displacement of the movable beam. In some embodiments, the monitor may monitor the distance between the movable electrode and at least one of the stationary electrodes. The MEMS device further has a voltage reducing circuit operatively coupled with the monitor, the movable electrode, and the stationary electrodes. The voltage reducing circuit reduces the differential between the third voltage and the voltages on the stationary electrodes when the monitor detects that the displacement of the movable beam is greater than or equal to a threshold value.09-15-2011

Patent applications by Howard R. Samuels, Newton, MA US

Jacquelin Samuels, Fairview, TX US

Patent application numberDescriptionPublished
20100251769Adjustable Jewelry Assembly - An adjustable jewelry assembly includes an adjustable bail member adapted for connection to a flexible jewelry member, a primary pendant removably connected to the bail member and/or and a secondary pendant removably connected to the bail member behind the primary pendant. At least a portion of the secondary pendant is viewable through the primary pendant. The secondary pendant can be connected to the bail member with first and second decorative surfaces facing either forwardly or rearwardly. Each surface has one or more distinguishing visual features and multiple pendants can be interchanged, stacked on the pendant, and/or reversed to thereby accommodate a user's clothing type and fashion preferences with a minimum number of jewelry pieces.10-07-2010

Jay Samuels, St. Paul, MN US

Patent application numberDescriptionPublished
20080311547System and methods for a reading fluency measure - The present invention measures reading fluency, which is simultaneous decoding and comprehension. Whether or not a person is a fluent reader is determined by the size of the visual unit, or sting of letters, used in word recognition In order to measure the size of the visual unit used in word recognition, a lexical decision task (“LDT”) is used in which short and long words are presented on a display device. The person determines if the string of letters formulates a word. The person enters their response on an input device and the results are recorded. A score is calculated that measures reading fluency. The ability to correctly identify a string of letters as a word using holistic processing, rather than letter-by-letter, is the hallmark of a fluent person.12-18-2008

Jonathan H. Samuels, Santa Barbara, CA US

Patent application numberDescriptionPublished
20110015952LIFE INSURANCE OPTION - A method of providing deferred life insurance through a life insurance option. The deferred life insurance becomes effective later in the life of an insured after the option matures. The insured pays at least one payment during a first period for the deferred life insurance policy option. The deferred life insurance policy is inactive during the first period, and becomes effective at the beginning of the second period when the option matures. The insured pays at least one payment during a second period, which follows the first period, for the deferred life insurance policy, assuming the insured lives this long. The insured is entitled to a benefit based on the deferred term life insurance policy only in the event of death of the insured occurs during the second period. Payments for the life insurance option can be made by a person who is the insured or on behalf of another person who is the insured, such as a child or other third party. The individual payments and sum of payments can be structured to suit the insured's financial objectives, while providing incoming funds to an insurance company. The deferred life insurance policy can be used in conjunction with a conventional life insurance policy, such as conventional term and whole life insurance policies.01-20-2011

Louann Behymer Samuels, Georgetown, KY US

Patent application numberDescriptionPublished
20100032883Kiosk-Installable Printer with Duplex Path Utilized to Deliver Printed Media Sheets to Lower Front Exterior of Printer - An image forming device includes an image formation path extending from an entrance end adjacent to a source of supply of media sheets, past an image forming station, to an exit end adjacent to a top collection site adapted to receive media sheets, a duplex path extending from an inlet end adjacent the top collection site to an outlet end adjacent a lower front opening in the device, a media sheet directing mechanism disposed between the exit end of the image formation path, top collection site and inlet end of the duplex path and selectively operable to deliver printed media sheets to the top collection site or the inlet end of the duplex path, and a deflector mechanism between the lower front opening and the outlet end of the duplex path and operable to divert printed media sheets from the duplex path through the lower front opening to exterior of the device.02-11-2010
20100166469System and Drive Arrangement for Using Fuser Temperature Cycling to Change Rotational Position of a Fuser Roller Wiper - A system and drive arrangement for using fuser temperature cycling to change rotational position of a fuser roller wiper includes a frame, a hot roll, a fuser roller, and a drive arrangement. The frame of the fuser unit has side panels spaced apart from one another and positioned alongside a media path through the fuser unit. The hot roll on the fuser unit is rotatably mounted to the side panels of the frame and extends between the side panels across the media path. The fuser roller wiper is rotatably mounted between the side panels of the frame and performs a wiping action on the hot roll to remove foreign matter therefrom and supply of lubricant thereto. The drive arrangement is coupled to the fuser roller wiper and is operable in response to decrease in temperature of the fuser unit to rotate the fuser roller wiper.07-01-2010
20110133615Electronic Locking System to Secure Consumable Item in an Image Forming Device and a Method Therefor - An electronic locking system to secure consumable items in an image forming device and a method therefore. In one embodiment of the invention, an electronic locking system to secure media sheets includes a media tray to hold media sheets, a tray receiving member for receiving the media tray, and a controller. The tray receiving member includes a drive device and a plunger. The plunger is moved by the drive device between a locked and an unlocked position. The controller is configured to control the drive device to move the plunger to engage a portion of the media tray in the locked position and to move the plunger to disengage from the portion of the media tray in the unlocked position. The electronic locking system, incorporating the controller, provides an effective and efficient way to lock/unlock the media tray and eliminates the use of mechanical keys.06-09-2011

Lovann Behymer Samuels, Georgetown, KY US

Patent application numberDescriptionPublished
20100329766DEVICE AND METHOD FOR PRINTING BANNER MEDIA - An apparatus and method for printing banner media utilizing a conventional laser printer wherein no or substantially no modification is required to the paper tray of the laser printer. The apparatus further includes a storage compartment that can be operably coupled with the paper tray. Disposed within the storage compartment is a plurality of rotatably mounted spools having a banner media stored thereon. Additionally, an alternative method of configuring banner media in a conventional paper tray is provided whereby the banner print media is configured in one of a z-fold configuration and a modified z-fold configuration, with the modified z-fold configuration to inhibit creases in the banner print media.12-30-2010

Mark A. Samuels, Johns Creek, GA US

Patent application numberDescriptionPublished
20110120438LOW VELOCITY PROJECTILE AIMING DEVICE - Provided are devices for determining the correct aiming point of a low velocity projectile and methods and systems for using the devices. For example, the devices can be attached to a bow and used to improve accuracy for hunting game05-26-2011

Martin L. Samuels US

Patent application numberDescriptionPublished
20110247075METHOD AND APPARATUS FOR ENABLING SECURE DISTRIBUTION OF DIGITAL CONTENT - A digital content management system includes a host machine and a delivery machine remote from the host machine. The host machine sends validation agent software to the delivery machine, which executes the validation agent. The validation agent performs one or more tests or observations to determine whether the delivery machine has been compromised, and communicates the results of the tests or observations to the host machine. If the host machine determines that the delivery machine has not been compromised, the host machine sends digital content to the delivery machine, and a player module at the delivery machine delivers the content to the user according to an appropriate set of access rights. After delivering the content, the delivery machine deletes the content to prevent unwanted access to the content. The content can contain signals indicative that the content is legitimate, such as watermarks or bad code segments or sectors.10-06-2011

Michael Samuels, Windham, NH US

Patent application numberDescriptionPublished
20100022414Droplet Libraries - The present invention generally relates to droplet libraries and to systems and methods for the formation of libraries of droplets. The present invention also relates to methods utilizing these droplet libraries in various biological, chemical, or diagnostic assays.01-28-2010

Michael Samuels, Branford, CT US

Patent application numberDescriptionPublished
20090099029Methods and substrates for conducting assays - The present invention relates to methods of conducting kinase assays using a myelin basic protein subtrate and a tyrosine kinase. Also provided herein are compositions that include myelin basic protein and a tyrosine kinase. Illustrative embodiments of these assays are performed on a microarray. In another embodiment, provided herein is a universal substrate that includes myelin basic protein.04-16-2009

Philip Samuels, St. Louis, MO US

Patent application numberDescriptionPublished
20090019707Cutting Guide for Electric Scissors - A cutting guide for use in cutting material using electric scissors or a similar tool includes an elongate cutting channel extending along a support surface. Opposing lower sections of side walls generally adjacent to a bottom of the channel are generally parallel and define a lower region of the channel therebetween having a generally uniform width for receiving a counter-blade of the electric scissors and allowing sliding movement of the counter-blade along the length of the channel. An upper region of the channel has a width greater than the width of the lower region of the channel for receiving a shearing blade of the scissors and permitting the oscillating movement of the shearing blade with respect to the counter-blade when the counter-blade is received in the lower region of the channel.01-22-2009

Robert J. Samuels, Atlanta, GA US

Patent application numberDescriptionPublished
20100229758Composite Materials Having Low Filler Percolation Thresholds and Methods of Controlling Filler Interconnectivity - Composite materials are disclosed having low filler percolation thresholds for filler materials into the composite matrix material along with methods of controlling filler interconnectivity within the composite matrix material. Methods are, thus, disclosed that provide the ability to control the desired properties of the composites. The composites of the present disclosure are characterized by a “pseudo-crystalline” microstructure formed of matrix particles and filler particles where the matrix particles are faceted and substantially retain their individual particle boundaries and where the filler particles are interspersed between the matrix particles at the individual matrix particle boundaries such that the filler particles form a substantially interconnected network that substantially surrounds the individual faceted matrix particles. In an exemplary embodiment, the composites are formed by selecting matrix particles and filler particles wherein the ratio of the average size of the matrix particles to the average size of the filler particles is about 10 or more. The selected matrix particles exhibit a glass transition temperature. The matrix particles and the filler particles are mechanically mixed and then subjected to a temperature above the glass transition temperature of the matrix particles and a compression pressure for a period of time sufficient to cause the matrix particles to undergo deformation so as to compress them together eliminating void spaces between the particles without melting the matrix material. The method is also demonstrated to work in combination with more standard art methods such as solution mixing for the purposes of achieving additional control of the properties.09-16-2010

Ross D. Samuels, Coppell, TX US

Patent application numberDescriptionPublished
20080203184Pneumatic Seasoning System - A pneumatic seasoning system and method utilizing a rotating drum for seasoning, a funnel-fed pneumatic eductor, line splitters, and a plurality of specially-designed swirl-inducing nozzle spools for inducing a broad and even seasoning plume. In a preferred embodiment, a pneumatic seasoning system transports seasoning from a seasoning hopper to food items within a rotating drum using a combination of an eductor and four in-line vacuum generators, which vacuum generators operate on compressed air. Each vacuum generator comprises a distributing nozzle roughly shaped like a collared spool, wherein compressed air is supplied to the annular region defined between the spool and its collar, and said compressed air exits through swirl ports distributed about the circumference of the spool exit. Each swirl port preferably has a pitch angle of 15° and a yaw angle of 15°.08-28-2008
20110020514PNEUMATIC SEASONING SYSTEM - A pneumatic seasoning system and method utilizing a rotating drum for seasoning, a funnel-fed pneumatic eductor, line splitters, and a plurality of specially-designed swirl-inducing nozzle spools for inducing a broad and even seasoning plume. In a preferred embodiment, a pneumatic seasoning system transports seasoning from a seasoning hopper to food items within a rotating drum using a combination of an eductor and four in-line vacuum generators, which vacuum generators operate on compressed air. Each vacuum generator comprises a distributing nozzle roughly shaped like a collared spool, wherein compressed air is supplied to the annular region defined between the spool and its collar, and said compressed air exits through swirl ports distributed about the circumference of the spool exit. Each swirl port preferably has a pitch angle of 15° and a yaw angle of 15°.01-27-2011

Rudy Lucas Samuels, San Francisco, CA US

Patent application numberDescriptionPublished
20100126046Snowshoe with flexible tail - A snowshoe of molded plastic material has a tail section with greater flexibility than the main body section, thereby allowing the tail to give and deform as the snowshoe tail is engaged against the terrain during the gait of the user. At the same time, the tail is stiff enough to provide flotation needed when the full weight of the user is on one snowshoe fully engaged against terrain, such as soft snow.05-27-2010
20100132225Molded snowshoe with pliable heel contact area - A molded plastic snowshoe of the type with a boot binding permitting pivoting in the pitch direction has a boot heel contact area formed of a flexible material. This provides for a soft strike as the boot comes in contact with the snowshoe deck in each step, eliminating the noise that usually accompanies the heel strike on a hard deck, and also increases comfort in use of the snowshoe, with the hard strike feel eliminated. Another advantage is that with a cleat mounted at the bottom of the soft section of decking the snowshoe adapts better to irregularities of terrain since the heel cleat is essentially suspended relative to the stiffer molded portions of the snowshoe. The flexibly suspended heel cleat can be pushed down to engage with snow or ice despite the irregular surface of the terrain and the rigidness of the snowshoe deck surrounding the cleat area.06-03-2010

Rudy Lucas Samuels, Mill Valley, CA US

Patent application numberDescriptionPublished
20110173844Molded snowshoe with compound deck - A molded or plastic composite snowshoe is formed of two assembled sections, in a way that imparts flexibility to the snowshoe, allowing some degree of torsional twisting or warping flexibility so that the snowshoe adapts to uneven terrain. In a principal embodiment the molded snowshoe is divided into forward and aft sections along a line slightly behind the nose area and near the pivot axis in the case of a pitch-pivoting binding. Joints between sections are in narrow rims at left and right, at opposed sides of a large central opening for the crampon/binding and boot. The joints are designed to securely hold the forward and aft molded sections together but to allow a degree of torsion between them when needed. Steel structural traction rails extend across the joints but are constructed and secured to the snowshoe sections in a manner that preserves the desired flexibility.07-21-2011

Samuel Lee Samuels, Bloomfield, NJ US

Patent application numberDescriptionPublished
20110048369Combination Piston and Variable Blade Turbine Internal Combustion Engine - Internal combustion engine has intake with compression in piston/cylinders and combustion and exhaust in a turbine. Turbine assembly includes a rotor connected to an output shaft and has variable blades pivotally mounted to rotor. The output shaft is connected to a crankshaft that is connects to the pistons to synchronizes intake and compression with combustion and exhaust. While the rotor spins centrifugal force causes the blades to swivel outwardly. The blades swivel inboard of the rotor as the space between them and the turbine housing cam contour gradually decreases. After partial compression, air enters the turbine assembly's combustion and exhaust chamber. Once full compression is attained, combustion takes place initiating a power cycle causing the turbine to rotate. When the power cycle is completed, the inner cam contour forces the blades inboard and exhaust is cleared by the subsequent variable blade, facilitating the next combustion and exhaust cycle.03-03-2011

Shaun L.w. Samuels, Coral Gables, FL US

Patent application numberDescriptionPublished
20100292772ENDOVASCULAR ROUTER DEVICE AND METHOD - A router device is a intraluminal prosthesis which is used in the repair of aneurysms and other diseases of the aorta. The device also has applications in other vascular beds. The device incorporates an inflatable cuff or sequence of cuffs at one end for fixation and sealing. This cuff may be placed proximal to branch vessels of the aorta. Attached to the cuff is a tubular graft consisting of a generally cylindrical graft material. The graft material may contain one or more fenestrations, intended to align with branch vessels as they emerge from the parent vessel, the aorta in the preferred embodiment. The device features a deliberate taper of its diameter as the device crosses the area of branch vessels. This taper brings the diameter of the graft material to a lesser diameter than that of the parent vessel, leaving a deliberate and distinct space between the device and the wall of the vessel. This space allows more easily achieved engagement of the branch vessels with stents using standard catheterization techniques.11-18-2010

Sheldon M. Samuels, Plano, TX US

Patent application numberDescriptionPublished
20090313659Campus Audio-Visual Control and Communication System - A method and system for distributing audio, visual, data, annunciator and other information within an educational facility utilizes a bit-wise addressing scheme to route UDP message packets to individual classrooms. The audio/video network system includes a central processor that controls a plurality of audio/video sources (e.g., DVD players, cable TV receivers, etc.). Output from audio/video sources is encoded by audio/video encoders for transmission via a local area network. Classroom control hubs within each classroom recognize data packets addressed with the bit-wise addressing scheme and in combination with a video decoder, recover the encoded audio/video signal for presentation within the classroom, such as by a video projector and classroom speakers. Transmitting audio/video information in UDP packets addressed with the bit-wise addressing scheme enables near simultaneous presentation of audio and video programs throughout the educational facility. The system can also manage traditional school bells and public address functions.12-17-2009

William D. Samuels, Richland,, WA US

Patent application numberDescriptionPublished
20090317545ALUMINIDE COATINGS - Disclosed herein are aluminide coatings. In one embodiment coatings are used as a barrier coating to protect a metal substrate, such as a steel or a superalloy, from various chemical environments, including oxidizing, reducing and/or sulfidizing conditions. In addition, the disclosed coatings can be used, for example, to prevent the substantial diffusion of various elements, such as chromium, at elevated service temperatures. Related methods for preparing protective coatings on metal substrates are also described.12-24-2009
20100147770FUNCTIONALIZED CARBON SORBENT AND PROCESS FOR SELECTIVE CAPTURE OF PRESELECTED METALS - A composition and process are described that provide for selective capture of targeted materials, including metals and chemical targets. The composition includes an activated carbon scaffold that is chemically modified to include ligands with a high affinity for selective capture of metals and chemical targets. The invention finds use, e.g., as heavy metal sorbents, as catalyst supports, in analytical applications such as ion chromatography, and in devices such as analytical instruments and chemical sensors.06-17-2010

Patent applications by William D. Samuels, Richland,, WA US

Yardena Samuels, Potomac, MD US

Patent application numberDescriptionPublished
20090208505Mutations of the pik3ca gene in human cancers - Phosphatidylinositol 3-kinases (PI3Ks) are known to be important regulators of signaling pathways. To determine whether PI3Ks are genetically altered in cancers, we analyzed the sequences of the P13K gene family and discovered that one family member, PIK3CA, is frequently mutated in cancers of the colon and other organs. The majority of mutations clustered near two positions within the P13K helical or kinase domains. PIK3CA represents one of the most highly mutated oncogenes yet identified in human cancers and is useful as a diagnostic and therapeutic target.08-20-2009

Yardena Samuels, Baltimore, MD US

Patent application numberDescriptionPublished
20110059434P13k pathway mutations in cancer - Given the important role of protein kinases in pathways affecting cellular growth and invasion, we have analyzed 340 serine/threonine kinases for genetic mutations in colorectal cancers. Mutations in eight genes were identified, including three members of the phosphatidylinositol-3-kinase (PI3K) pathway; the alterations in the latter genes each occurred in different tumors and did not overlap with mutations in PIK3CA or other non-serine-threonine kinase (STK) members of the PI3K pathway, suggesting that mutations in any of these genes had equivalent tumorigenic effects. These data demonstrate that the PI3K pathway is a major target for mutational activation in colorectal cancers and provide new opportunities for therapeutic intervention.03-10-2011

Yardena R. Samuels, Potomac, MD US

Patent application numberDescriptionPublished
20110262437USE OF ERBB4 AS A PROGNOSTIC AND THERAPEUTIC MARKER FOR MELANOMA - It is disclosed herein that members of the protein tyrosine kinase (PTK) family are highly mutated in patients with melanoma. Described herein are novel somatic mutations in the ERBB4 gene that result in increased kinase activity, transformation ability and anchorage-independent growth. These ERBB4 mutations contribute to the tumorogenicity of melanoma. Thus, provided herein is a method of predicting the prognosis of a patient with melanoma by detecting the presence or absence of a mutation in the ERBB4 gene. In some examples, the ERBB4 mutation is selected from G949A, G1354A, G1624A, C1630T, G1687A, G2506A and G2614A (numbering based on SEQ ID NO: 1). Also provided are methods of selecting a patient as a candidate for treatment with an ERBB4 and/or PI3K/AKT pathway inhibitor, and a method of identifying a therapeutic agent for the treatment of a subject diagnosed with melanoma. Oligonucleotides that specifically hybridize with an ERBB4 nucleic acid molecule comprising a novel mutation, and arrays comprising such oligonucleotides, are also provided.10-27-2011