Patent application number | Description | Published |
20090052385 | MULTIPLE ACCESS SERVICE CONVERGENCE - A mobile terminal is anchored in a control subsystem, which will function as the mobile terminal's home service subsystem. Call signaling for an incoming call is routed to the control subsystem, which will provide call processing. The call processing may include determining how to route the call to the mobile terminal. Call signaling may be provided to the mobile terminal via the packet subsystem while the bearer path for the incoming call may be established to the mobile terminal though either the circuit-switched subsystem or the packet subsystem. When the mobile terminal is capable of supporting local wireless communications, the bearer paths for incoming calls may be provided via a local wireless subsystem. The subsystem chosen for the bearer path may be based on whether there is sufficient bandwidth to support the bearer path over an available packet-based connection. | 02-26-2009 |
20100115105 | MOBILITY IN A MULTI-ACCESS COMMUNICATION NETWORK - The present invention provides a terminal capable of establishing multiple communication sessions with a public network proxy through different access networks. The terminal actively communicates with the public network proxy to control which of the multiple communication paths are active, as well as control the transition from actively using one communication path to using another. The public network proxy facilitates data and voice sessions between the terminal and any number of other communication devices. In one embodiment, the communication sessions are reserved tunneling sessions, and the terminal cooperates with the public network proxy to effectively control how many tunneling-sessions are established, how many tunneling sessions are active at any given time, and the transition from one tunneling session to another for active communications. Each of the communication or tunneling sessions may be established over different access networks using different communication technologies and protocols. | 05-06-2010 |
20110213891 | INTEGRATED HOME SERVICE NETWORK - The present invention provides a centralized home controller that is used to coordinate a plurality of associated packet communication clients. The home controller provides a centralized and unified control and messaging system for the various packet communication clients. The home controller also allows the packet communication clients to establish and control packet sessions among the associated packet communication clients, as well as between any one of the packet communication clients and remote clients. The packet communication clients are provided in consumer electronics devices, and the associated packet sessions support data, voice, audio, or video content. In one embodiment, the home controller acts as a proxy for the various communications between the packet communication clients. | 09-01-2011 |
20130006910 | CLINICAL DECISION SUPPORT SYSTEMS, APPARATUS, AND METHODS - A system includes a centralized repository for tracking rule content and managing subscriptions to rule content by organizations and providers utilizing the system; a rule-evaluation server for receiving requests for rule-evaluations for specific patients, wherein the server determines content needing to be evaluated and retrieves the content to be used; a rule engine for performing the evaluations, wherein content, patient data, and rule evaluation parameters are provided to the engine, and the engine returns recommendations triggered by the evaluation, if any; an aggregator for aggregating recommendations from multiple sources, detecting and coordinating related recommendations, and applying configuration settings based on the patient and/or provider in context; and a client component for coordinating communication between an electronic health records system, the server, and the aggregator. | 01-03-2013 |
20130006911 | CLINICAL DECISION SUPPORT SYSTEMS, APPARATUS, AND METHODS - A system includes a centralized repository for tracking rule content and managing subscriptions to rule content by organizations and providers utilizing the system; a rule-evaluation server for receiving requests for rule-evaluations for specific patients, wherein the server determines content needing to be evaluated and retrieves the content to be used; a rule engine for performing the evaluations, wherein content, patient data, and rule evaluation parameters are provided to the engine, and the engine returns recommendations triggered by the evaluation, if any; an aggregator for aggregating recommendations from multiple sources, detecting and coordinating related recommendations, and applying configuration settings based on the patient and/or provider in context; and a client component for coordinating communication between an electronic health records system, the server, and the aggregator. | 01-03-2013 |
20130006912 | CLINICAL DECISION SUPPORT SYSTEMS, APPARATUS, AND METHODS - A system includes a centralized repository for tracking rule content and managing subscriptions to rule content by organizations and providers utilizing the system; a rule-evaluation server for receiving requests for rule-evaluations for specific patients, wherein the server determines content needing to be evaluated and retrieves the content to be used; a rule engine for performing the evaluations, wherein content, patient data, and rule evaluation parameters are provided to the engine, and the engine returns recommendations triggered by the evaluation, if any; an aggregator for aggregating recommendations from multiple sources, detecting and coordinating related recommendations, and applying configuration settings based on the patient and/or provider in context; and a client component for coordinating communication between an electronic health records system, the server, and the aggregator. | 01-03-2013 |
20140040486 | MOBILITY IN A MULTI-ACCESS COMMUNICATION NETWORK - Various embodiments provide a terminal capable of establishing multiple communication sessions with a public network proxy through different access networks. The terminal actively communicates with the public network proxy to control which of the multiple communication paths are active, as well as control the transition from actively using one communication path to using another. The public network proxy facilitates data and voice sessions between the terminal and any number of other communication devices. In one embodiment, the communication sessions are reserved tunneling sessions, and the terminal cooperates with the public network proxy to effectively control how many tunneling sessions are established, how many tunneling sessions are active at any given time, and the transition from one tunneling session to another for active communications. Each of the communication or tunneling sessions may be established over different access networks using different communication technologies and protocols. | 02-06-2014 |
20140112336 | TELEPHONY USAGE DERIVED PRESENCE INFORMATION - The present invention relates to a mechanism for providing state information, which bears on the presence of a telephone user, to a presence system. The state information is derived by monitoring events relating to telephony use. Once derived, the state information is directly or indirectly sent to a presence service, which provides presence information to applications requiring such information about the telephone user. The state information preferably bears on the presence, absence, or availability of the telephone user based on their interaction with a telephony device or function. In one embodiment, a telephony switching system is configured to monitor events associated with a telephony device or function and send messages to a presence service over a packet-switched network when the state of the telephony device or function changes. In another embodiment, an IP telephone system is configured to provide state information to the presence service. | 04-24-2014 |
20140146714 | INTEGRATED HOME SERVICE NETWORK - A centralized home controller that is used to coordinate a plurality of associated packet communication clients is described herein. The home controller provides a centralized and unified control and messaging system for the various packet communication clients. The home controller also allows the packet communication clients to establish and control packet sessions among the associated packet communication clients, as well as between any one of the packet communication clients and remote clients. The packet communication clients are provided in consumer electronics devices, and the associated packet sessions support data, voice, audio, or video content. In one embodiment, the home controller acts as a proxy for the various communications between the packet communication clients. | 05-29-2014 |
20140146952 | Audio Call Screening for Hosted Voicemail Systems - The present invention allows a user to screen messages being left at a hosted voicemail system from a telephone terminal. Incoming calls intended for the telephone terminal are routed to the voicemail system immediately or after attempting to connect incoming call to the telephone terminal. As the caller is leaving a message at the voicemail system, a connection between the incoming call, voicemail system, and telephone terminal is established to allow the user to listen to the message and decide whether to take the call. The user may decide to take the call or let the caller finish leaving the message. In one embodiment, the telephone terminal is equipped to open only the speaker channel for monitoring the message and will provide a fully bi-directional connection if the user takes the call. The supporting switch and telephone terminal communicate with each other to facilitate the monitoring and taking of calls. | 05-29-2014 |
Patent application number | Description | Published |
20090299098 | Catalytic Metathesis of Secondary Amides - The invention provides methods and reagents for the metathesis of secondary amides via a transacylation mechanism employing catalytic quantities of an imide initiator and a Brønsted base. Equilibrium-controlled exchange between various amide reactant pairs is demonstrated for substrates bearing a variety of N-alkyl and N-aryl substituents. | 12-03-2009 |
20100021344 | BETA-PEPTIDE LYOTROPIC LIQUID CRYSTALS AND METHODS OF MANUFACTURE AND USE THEREOF - The present invention provides materials and methods that make liquid crystal phases accessible with relatively short β-peptides in aqueous solvents. | 01-28-2010 |
20100099185 | METHOD OF MAKING BIOLOGICALLY ACTIVE ALPHA-BETA PEPTIDES - Described is a method of fabricating biologically active, unnatural polypeptides. The method includes the steps of selecting a biologically active polypeptide or biologically active fragment thereof having an amino acid sequence comprising α-amino acid residues, and fabricating a synthetic polypeptide that has an amino acid sequence that corresponds to the sequence of the biologically active polypeptide, but wherein about 14% to about 50% of the α-amino acid residues found in the biologically active polypeptide or fragment of step (a) are replaced with β-amino acid residues, and the α-amino acid residues are distributed in a repeating pattern. | 04-22-2010 |
20100222250 | POLY-BETA-PEPTIDES FROM FUNCTIONALIZED BETA-LACTAM MONOMERS AND ANTIBACTERIAL COMPOSITIONS CONTAINING SAME - Disclosed is a method of making β-polypeptides. The method includes polymerizing β-lactam-containing monomers in the presence of a base initiator and a co-initiator which is not a metal-containing molecule to yield the product β-polypeptides. Specifically disclosed are methods wherein the base initiator is potassium t-butoxide, lithium bis(trimethylsilyl)amide (LiN(TMS) | 09-02-2010 |
20110196127 | POLY-BETA-PEPTIDES FROM FUNCTIONALIZED BETA-LACTAM MONOMERS AND ANTIBACTERIAL COMPOSITIONS CONTAINING SAME - Disclosed is a method of making β-polypeptides. The method includes polymerizing β-lactam-containing monomers in the presence of a base initiator and a co-initiator which is not a metal-containing molecule to yield the product β-polypeptides. Specifically disclosed are methods wherein the base initiator is potassium t-butoxide, lithium bis(trimethylsilyl)amide (LiN(TMS) | 08-11-2011 |
20120021530 | HETEROGENEOUS FOLDAMERS CONTAINING alpha, beta, and/or gamma-AMINO ACIDS - Disclosed are isolated, unnatural polypeptides containing cyclically-constrained β-amino acid residues and cyclically-constrained γ-amino acid residues. The compounds are unnatural and because they contain rotationally constrained residues that are not amenable to enzymatic degradation, the compounds are useful to probe protein-protein and other large molecule interactions. | 01-26-2012 |
20130004453 | NYLON-3 CO-POLYMERS AND SYNTHETIC LUNG SURFACTANT COMPOSITIONS CONTAINING SAME - Non-natural oligomers have recently shown promise as functional analogues of lung surfactant proteins Band C (SP-B and SP-C), two helical and amphiphilic proteins that are clitical for normal respiration. The generation of non-natural mimics of SP-B and SP-C has previously been restlicted to step-by-step, sequence-specific synthesis, which results in discrete oligomers that are intended to manifest specific structural attributes. Presented herein an alternative approach to SP-R mimicry that is based on sequence-random copolymers containing cationic and lipophilic subunits. These materials, members of the nylon-3 family, arc prepared by ling-opening polymelization of 13-lactams. The best of the nylon-3 polymers display promising in vitro surfactant activities in a mixed lipid film. Pulsating bubble surfactometry data indicate that films containing the most surface-active polymers attain adsorptive and dynamic-cycling properties that surpass those of discrete peptides intended to mimic SP-B. | 01-03-2013 |
20130023644 | BETA-AMINO ACIDS - Disclosed are β-amino acid monomers containing cylcoalkyl, cycloalkenyl, and heterocylic substituents which encompass the α and β carbons of the peptide backbone and β-polypeptides made from such monomers. Method of generating combinatorial libraries of polypeptides containing the β-peptide residues and libraries formed thereby are disclosed. | 01-24-2013 |
20130177981 | METHOD OF MAKING BIOLOGICALLY ACTIVE ALPHA-BETA PEPTIDES - Described is a method of fabricating biologically active, unnatural polypeptides. The method includes the steps of selecting a biologically active polypeptide or biologically active fragment thereof having an amino acid sequence comprising α-amino acid residues, and fabricating a synthetic polypeptide that has an amino acid sequence that corresponds to the sequence of the biologically active polypeptide, but wherein about 14% to about 50% of the α-amino acid residues found in the biologically active polypeptide or fragment of step (a) are replaced with β-amino acid residues, and the α-amino acid residues are distributed in a repeating pattern. | 07-11-2013 |
20140121154 | Compositions Comprising Glucagon Analogs And Methods Of Making And Using The Same - This invention relates to novel compositions comprising analogs of glucagon, wherein the analog comprises an α-amino acid and at least one β-amino acid. Administration of the compositions may be used for effecting treatment or prevention of a plurality of disease states caused by dysfunctional biochemical or biological pathways, including diabetes and other metabolic disorders. The compositions and methods of this invention are particularly useful to identify novel therapeutic modulators of in-vivo receptor activity with extended half-lives and relevant bioactivity as compared to the naturally translated polypeptides upon which the analogs are derived. | 05-01-2014 |
20140315791 | METHOD OF MAKING BIOLOGICALLY ACTIVE ALPHA-BETA PEPTIDES - Described is a method of fabricating biologically active, unnatural polypeptides. The method includes the steps of selecting a biologically active polypeptide or biologically active fragment thereof having an amino acid sequence comprising α-amino acid residues, and fabricating a synthetic polypeptide that has an amino acid sequence that corresponds to the sequence of the biologically active polypeptide, but wherein about 14% to about 50% of the α-amino acid residues found in the biologically active polypeptide or fragment of step (a) are replaced with β-amino acid residues, and the α-amino acid residues are distributed in a repeating pattern. | 10-23-2014 |
20140378375 | ALPHA/BETA-POLYPEPTIDE ANALOGS OF GLUCAGON-LIKE PEPTIDE 1 - Described herein are peptide analogs of glucagon-like peptide 1 (GLP-1) that retain agonist activity, but are more resistant to proteolytic degradation than native GLP-1. In the analogs, at least one α-amino acid found in the native GLP-1 is replaced with a β-amino acid residue, which may or may not be cyclically constrained. Pharmaceutical compositions containing the analogs are described, as are methods to treat diabetes, and methods to make proteolytically resistant GLP-1 analogs. | 12-25-2014 |
20140378382 | ALPHA-/BETA-POLYPEPTIDE ANALOGS OF PARATHYROID HORMONE (PTH) AND METHOD OF USING SAME - Described are polypeptide analogs of parathyroid hormone (PTH) that include at least two non-adjacent β-amino acid residues in place of a naturally occurring α-amino acid residues. Also described are pharmaceutical compositions useful for treating hypoparathyroidism that contain the analogs and methods of using the analogs to treat hypoparathyroidism. | 12-25-2014 |
20150051141 | Compositions Comprising Glucagon Analogs And Methods Of Making And Using The Same - This invention relates to novel compositions comprising analogs of glucagon, wherein the analog comprises an α-amino acid and at least one β-amino acid. Administration of the compositions may be used for effecting treatment or prevention of a plurality of disease states caused by dysfunctional biochemical or biological pathways, including diabetes and other metabolic disorders. The compositions and methods of this invention are particularly useful to identify novel therapeutic modulators of in-vivo receptor activity with extended half-lives and relevant bioactivity as compared to the naturally translated polypeptides upon which the analogs are derived. | 02-19-2015 |
20150203555 | ALPHA/BETA-PEPTIDE MIMICS OF Z-DOMAIN PEPTIDES - Described are α/β-peptide mimics of Z-domain scaffold peptides, methods of making them, and methods of using them. The α/β-peptide mimics include β-amino acid residues and, optionally, disulfide bonds to stabilize the conformation of the mimics. The compounds may be truncated as compared to conventional Z-domain scaffold peptides and are resistant to proteolytic degradation due to the presence of β-amino acid residues. The mimics can be made so as to bind selectively to a desired target. | 07-23-2015 |
20150224135 | BIOCIDAL POLYMERS - Pharmaceutical compositions containing biocidal co-polymers of poly(styrenes), poly(acrylates), poly(acrylamides), and poly(C | 08-13-2015 |
20150231171 | NYLON-3 CO-POLYMERS AND SYNTHETIC LUNG SURFACTANT COMPOSITIONS CONTAINING SAME - Non-natural oligomers have recently shown promise as functional analogues of lung surfactant proteins B and C (SP-B and SP-C), two helical and amphiphilic proteins that are critical for normal respiration. The generation of non-natural mimics of SP-B and SP-C has previously been restricted to step-by-step, sequence-specific synthesis, which results in discrete oligomers that are intended to manifest specific structural attributes. Presented herein an alternative approach to SP-B mimicry that is based on sequence-random copolymers containing cationic and lipophilic subunits. These materials, members of the nylon-3 family, are prepared by ring-opening polymerization of β-lactams. The best of the nylon-3 polymers display promising in vitro surfactant activities in a mixed lipid film. Pulsating bubble surfactometry data indicate that films containing the most surface-active polymers attain adsorptive and dynamic-cycling properties that surpass those of discrete peptides intended to mimic SP-B. Attachment of an N-terminal octadecanoyl unit to the nylon-3 copolymers affords further improvements by reducing the percent surface area compression to reach low minimum surface tension. | 08-20-2015 |
20150322205 | POLY-BETA-PEPTIDES FROM FUNCTIONALIZED BETA-LACTAM MONOMERS AND ANTIBACTERIAL COMPOSITIONS CONTAINING SAME - Disclosed is a method of making β-polypeptides. The method includes polymerizing β-lactam-containing monomers in the presence of a base initiator and a co-initiator which is not a metal-containing molecule to yield the product β-polypeptides. Specifically disclosed are methods wherein the base initiator is potassium t-butoxide, lithium bis(trimethylsilyl)amide (LiN(TMS) | 11-12-2015 |
20160045572 | PEPTIDES COMPRISING NON-NATURAL AMINO ACIDS AND METHODS OF MAKING AND USING THE SAME - This invention relates to novel compositions comprising analogs of naturally occurring polypeptides, wherein the analog comprises an α-amino acid and at least one β-amino acid. Administration of the compositions may be used for effecting treatment or prevention of a plurality of disease states caused by dysfunctional biochemical or biological pathways. The compositions and methods of this invention are particularly useful to identify novel therapeutic modulators of in-vivo receptor activity with extended half-lives and relevant bioactivity as compared to the naturally translated polypeptides upon which the analogs are derived. | 02-18-2016 |
Patent application number | Description | Published |
20080320296 | METHODS AND SYSTEMS FOR SECURE REMOTE MOBILE PRINTING - Systems and methods for for secure, remote printing includes a mobile device (e.g., cell phone or PDA) establishing a secure communication connection with a mobile printer and a server, such a connection using one or more encryption protocols (e.g., SSL, TLS, etc.). The server encrypts the requested data and transmits it to the printer via the secure connection, whereon the printer decrypts and prints the data. The mobile device can, according to other aspects of the invention, logs operational performance characteristic of the printer, the server, and/or the communication connections therebetween. A media cartridge can be provided includes an enclosure having a substantially planar shape, wherein each of its length and width dimensions are greater than its height. An opening is disposed along a width-wise edge (e.g., a “front” of the enclosure), and one or more regions are also disposed on opposing length-wise edges (e.g., a “left side” and a “right side” of the enclosure). The regions permit a user to see and/or exert a force on sheet media (e.g., paper) contained within the enclosure. | 12-25-2008 |
20090000969 | MEDIA CARTRIDGE AND METHOD FOR MOBILE PRINTING - Systems and methods for secure, remote printing includes a mobile device (e.g., cell phone or PDA) establishing a secure communication connection with a mobile printer and a server, such a connection using one or more encryption protocols (e.g., SSL, TLS, etc.). The server encrypts the requested data and transmits it to the printer via the secure connection, whereon the printer decrypts and prints the data. The mobile device can, according to other aspects of the invention, logs operational performance characteristic of the printer, the server, and/or the communication connections therebetween. A media cartridge can be provided includes an enclosure having a substantially planar shape, wherein each of its length and width dimensions are greater than its height. An opening is disposed along a width-wise edge (e.g., a “front” of the enclosure), and one or more regions are also disposed on opposing length-wise edges (e.g., a “left side” and a “right side” of the enclosure). The regions permit a user to see and/or exert a force on sheet media (e.g., paper) contained within the enclosure. | 01-01-2009 |