Ryan, PA
Christopher J. Ryan, West Chester, PA US
Patent application number | Description | Published |
---|---|---|
20100121329 | TRANSLATABLE CARRIAGE FIXATION SYSTEM - Translational bone fixation assemblies, kits containing such assemblies, and methods of use are described herein. The described assemblies may be used in spinal fusion procedures in which a damaged or diseased disc (or part of a disc) is removed from between a pair of vertebrae and a spinal fusion spacer is placed between the vertebrae. The assemblies may be applied to an anterior portion of the affected vertebrae to span the affected disc space, and may be fixed to the vertebrae using bone screws. The assemblies may function to maintain the vertebrae aligned during the initial period following fixation in which fusion of the spacer to the adjacent vertebrae occurs. The assemblies may also function to share some of the axial spinal load applied to the fusion spacer to prevent extreme subsidence of the spacer into the vertebral body, such as where the patient has poor bone quality. | 05-13-2010 |
20100324566 | DRILL-TAP-SCREW DRILL GUIDE - A surgical drill guide for use with a bone plate having fastener holes oriented at predetermined angles with respect to the plate, the surgical drill guide having at least one alignment drill guiding barrel that is aligned with the respective fastener holes in the bone plate for drilling the holes at the desired range of angles permitted by the plate hole. | 12-23-2010 |
20120283782 | TRANSLATABLE CARRIAGE FIXATION SYSTEM - Translational bone fixation assemblies, kits containing such assemblies, and methods of use are described herein. The described assemblies may be used in spinal fusion procedures in which a damaged or diseased disc (or part of a disc) is removed from between a pair of vertebrae and a spinal fusion spacer is placed between the vertebrae. The assemblies may be applied to an anterior portion of the affected vertebrae to span the affected disc space, and may be fixed to the vertebrae using bone screws. The assemblies may function to maintain the vertebrae aligned during the initial period following fixation in which fusion of the spacer to the adjacent vertebrae occurs. The assemblies may also function to share some of the axial spinal load applied to the fusion spacer to prevent extreme subsidence of the spacer into the vertebral body, such as where the patient has poor bone quality. | 11-08-2012 |
Colin P. Ryan, Wayne, PA US
Patent application number | Description | Published |
---|---|---|
20140335493 | TRAINING MANNEQUIN FOR USE IN SPARRING, SELF-DEFENSE, LAW ENFORCEMENT, AND COMBAT SPORTS TRAINING - A humanoid mannequin with jointed, positionable, and realistic reactive limbs. The mannequin is used in connection with sparring, self-defense, law enforcement, and combat sports training. The mannequin is constructed with a jointed endoskeleton frame that permits the mannequin limbs to be positioned in various training postures, and to realistically hold such positions against external forces exerted by a combatant. The mannequin skeleton also includes a series of elastic elements that allow the skeleton to be forced from its preset posture, and to recover that posture once the disturbing force is removed. The mannequin skeleton is covered by a durable flexible elastomer skin filled with a resilient supporting foam. This housing material provides the external anatomical features of a human body as well as the padding required to protect combatant users from the internal rigid skeletal components. | 11-13-2014 |
Daniel David Ryan, Chadds Ford, PA US
Patent application number | Description | Published |
---|---|---|
20100016760 | URETHRA GAUGE AND METHODS OF MANUFACTURE, AND OPERATION THEREOF - A urethra gauge for measuring an inner size of a urinary tract. The gauge permits a clinician to measure the size of the urethral lumen (proximal to an outer orifice of the urethra) before a catheterization is performed. Selecting a properly-sized catheter for insertion into a patient by measuring the size of the urethral lumen before performing a catheterization is believed to reduce: (1) catheter-associated-urinary-tract infections; (2) urethral injuries due to inserting a catheter that is too large for the urethra; and/or (3) leakage associated with catheters that are too small for a particular patient. | 01-21-2010 |
Jed Ryan, Erdenheim, PA US
Patent application number | Description | Published |
---|---|---|
20150269692 | Electronic Contract Creator - An electronic device creates a contract between two parties and includes an identity determiner that determines and verifies, based on an analysis of a photograph or biometric data of a party to the contract, personal information about the party. A contract creator creates the contract between the parties, and a wireless transmitter transmits the contract over a network to secure storage after the contract receives consent from both parties. | 09-24-2015 |
John Ryan, Philadelphia, PA US
Patent application number | Description | Published |
---|---|---|
20110152512 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTICS DELIVERY - Methods and compositions relating to CDP-epothilone conjugates are described herein. | 06-23-2011 |
20110160159 | TREATMENT OF CANCER - Provided are methods relating to compositions that include a CDP-topoisomerase inhibitor, e.g., a CDP-camptothecin or camptothecin derivative conjugate, e.g., CRLX101. | 06-30-2011 |
20110245201 | TREATMENT OF CANCER - Provided are methods relating to compositions that include a CDP-topoisomerase inhibitor, e.g., a CDP-camptothecin or camptothecin derivative conjugate, e.g., CRLX101. | 10-06-2011 |
20120064071 | TREATMENT OF CANCER - Provided are methods relating to compositions that include a CDP-topoisomerase inhibitor, e.g., a CDP-camptothecin or camptothecin derivative conjugate, e.g., CRLX101. | 03-15-2012 |
20120065161 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY - Methods and compositions relating to CDP-epothilone conjugates are described herein. | 03-15-2012 |
20120114658 | TREATMENT OF CANCER - Provided are methods relating to compositions that include a CDP-topoisomerase inhibitor, e.g., a CDP-camptothecin or camptothecin derivative conjugate, e.g., CRLX101. | 05-10-2012 |
20130029909 | TREATMENT OF CANCER - Provided are methods relating to compositions that include a CDP-topoisomerase inhibitor, e.g., a CDP-camptothecin or camptothecin derivative conjugate, e.g., CRLX101. | 01-31-2013 |
20130096293 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTICS DELIVERY - Methods and compositions relating to CDP-epothilone conjugates are described herein. | 04-18-2013 |
20130164282 | TREATMENT OF CANCER - Provided are methods relating to compositions that include a CDP-topoisomerase inhibitor, e.g., a CDP-camptothecin or camptothecin derivative conjugate, e.g., CRLX101. | 06-27-2013 |
20130338103 | TREATMENT OF CANCER - Provided are methods relating to compositions that include a CDP-topoisomerase inhibitor, e.g., a CDP-camptothecin or camptothecin derivative conjugate, e.g., CRLX101. | 12-19-2013 |
20140205594 | TREATMENT OF CANCER - Provided are methods relating to compositions that include a CDP-topoisomerase inhibitor, e.g., a CDP-camptothecin or camptothecin derivative conjugate, e.g., CRLX101. | 07-24-2014 |
20140288024 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTICS DELIVERY - Methods and compositions relating to CDP-epothilone conjugates are described herein. | 09-25-2014 |
20150141638 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTICS DELIVERY - Methods and compositions relating to CDP-epothilone conjugates are described herein. | 05-21-2015 |
John Ryan, Chalfont, PA US
Patent application number | Description | Published |
---|---|---|
20110009347 | COMBINATION THERAPY FOR THE TREATMENT OF DIABETES - The present invention is directed to co-therapy and methods for the treatment and prevention of glucose-related disorders such as Type 2 diabetes mellitus and Syndrome X. The present invention is further directed to pharmaceutical compositions for the co-therapy and methods described herein. | 01-13-2011 |
John L. Ryan, Philadelphia, PA US
Patent application number | Description | Published |
---|---|---|
20150238601 | TREATMENT OF OCULAR DISORDERS - The invention provides methods of treatment of ocular disorders, including ocular disease with an angiogenic component. In certain embodiments, the treatment comprises administration of a ROCK2 inhibitor and an angiogenesis inhibitor. In certain embodiments, the ROCK2 inhibitor is ROCK2 selective. In certain embodiments, the angiogenesis inhibitor is a VEGF antagonist, for example, and VEGFR2 antibody. | 08-27-2015 |
John Louis Ryan, Philadelphia, PA US
Patent application number | Description | Published |
---|---|---|
20090325176 | Gene Expression Profiles Associated with Asthma Exacerbation Attacks - The present invention provides methods for the assessment, diagnosis, or prognosis of asthma exacerbation, by assessing the level of expression of asthma exacerbation gene products in a sample derived from a patient. The markers of the present invention can be used in methods to identify or evaluate agents capable of modulating marker expression levels in subjects with asthma. | 12-31-2009 |
Ken Ryan, Huntingdon Valley, PA US
Patent application number | Description | Published |
---|---|---|
20100305245 | Color-Pigmented Paint Composition Having High Covering Powder, Increased Scratch Resistance, And Easy-To-Clean Properties - The present invention is directed to a color-pigmented paint composition with high hiding power, comprising a solvent or a solvent mixture and | 12-02-2010 |
Kevin P. Ryan, Zionsville, PA US
Patent application number | Description | Published |
---|---|---|
20130269275 | STAY-IN-PLACE CONCRETE FORM - A stay-in-place concrete form includes masonry shells layered with lightweight concrete and rigid insulation tied with plastic ladders. The masonry shells can be capped with plastic shims that compensate for the variation in height of the shells. This allows for the shells, together with the shims, to be a consistent height and allows for dry stacking. The masonry shells are bonded together with a layer of lightweight concrete poured in a cavity behind the masonry shells instead of being bonded together by mortar joints. This dry stacking method can result in labor time and training savings over conventional masonry mortar construction. | 10-17-2013 |
Kevin Patrick Ryan, Zionsville, PA US
Patent application number | Description | Published |
---|---|---|
20150089894 | STAY-IN-PLACE CONCRETE FORM - A stay-in-place concrete form includes masonry shells layered with rigid insulation tied with plastic cross tie assemblies. The masonry shells can be connected with plastic dovetail connectors that compensate for the variation in height of the shells. This allows for the shells, together with the connectors, to be a consistent height and allows for dry stacking. The masonry shells can be bonded together with a layer of lightweight concrete poured in a cavity behind the masonry shells and/or bonded together by mortar joints. This dry stacking method can result in labor time and training savings over conventional masonry mortar construction. | 04-02-2015 |
Kristin J. Ryan, Prospect Park, PA US
Patent application number | Description | Published |
---|---|---|
20110154772 | Moisture Curable Adhesive Composition and Method for Installing Hardwood Floors - An adhesive composition for adhesively bonding floor coverings to a variety of substrates. The composition includes 0.2 to 10 weight percent of a plurality of irregularly shaped spacer particles of size 0.5 mm to 10 mm; 10 to 50 weight percent of a moisture curable polymer system; and 40 to 90 weight percent of additives for modifying physical properties of the composition. The adhesive has a composition such that, when cured, results in an elastomeric film of uniform thickness that exhibits controlled moisture vapor transmission and sound abatement properties. A floor structure and a method for constructing the floor structure using the adhesive composition are also provided. | 06-30-2011 |
Mary Ryan, Radnor, PA US
Patent application number | Description | Published |
---|---|---|
20090155280 | Immunoglobulin Cleavage Fragments as Disease Indicators and Compositions for Detecting and Binding Such - The invention relates to antibody compositions and use of the composition to detect disease processes associated with elaboration of proteases. The reagents are directed to assessing an IgG breakdown product that is the result of such proteolytic cleavage. The invention further relates to the use of a therapeutic immunospecific for IgG breakdown products retaining antigen binding but having lost effector functions. | 06-18-2009 |
20120082622 | Macaca fascicularis CCL17 - Isolated polynucleotides encoding | 04-05-2012 |
20120108795 | Antibodies Binding Human Collagen II - The present invention relates to antibodies against human collagen II, polypeptides and polynucleotides encoding human collagen II antibodies or fragments thereof, and methods of making and using the foregoing. | 05-03-2012 |
Mary Ryan, Spring House, PA US
Patent application number | Description | Published |
---|---|---|
20130239238 | Immunoglobulin Cleavage Fragments and Disease Indicators and Compositions for Detecting and Binding Such - The invention relates to antibody compositions and use of the composition to detect disease processes associated with elaboration of proteases. The reagents are directed to assessing an IgG breakdown product that is the result of such proteolytic cleavage. The invention further relates to the use of a therapeutic immunospecific for IgG protease cleavage products to restore effector function to antibody compositions that are subject to protease cleavage. | 09-12-2013 |
20140220634 | Antibodies binding human collagen II - The present invention relates to antibodies against human collagen II, polypeptides and polynucleotides encoding human collagen II antibodies or fragments thereof, and methods of making and using the foregoing. | 08-07-2014 |
20150125458 | Anti-CCL17 Antibodies - The present invention relates to antibodies specifically binding CCL17, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing. | 05-07-2015 |
Michael D. Ryan, Drexel Hill, PA US
Patent application number | Description | Published |
---|---|---|
20080263998 | Methods and Systems for Packaging a Product - A method for applying a heat shrinkable film to a carton for forming a shape of the carton is provided. The carton includes a top panel, a bottom panel, at least one side panel extending between the top panel and the bottom panel, and a movable section that is movable between a first position and a second position. The method includes providing a heat-shrinkable but unshrunken film, wrapping the film in an unheated condition around at least a portion of the carton including at least a portion of the movable section of the carton, and moving the movable section from the first position to the second position to form a shape of the carton by heating the heat-shrinkable film to shrink the heat-shrinkable film into contact with at least a portion of the movable section. | 10-30-2008 |
Michael D. Ryan, Media, PA US
Patent application number | Description | Published |
---|---|---|
20100019022 | Package with Recloseable Dispenser - A package having a dispenser with recloseable features. The package has a recloseable flap that is positionable between an open position for accessing products within the package and a closed position preventing access to products within the package. | 01-28-2010 |
20100224526 | Methods and Systems for Packaging A Product - A method for applying a heat shrinkable film to a carton for forming a shape of the carton is provided. The carton includes a top panel, a bottom panel, at least one side panel extending between the top panel and the bottom panel, and a movable section that is movable between a first position and a second position. The method includes providing a heat-shrinkable but unshrunken film, wrapping the film in an unheated condition around at least a portion of the carton including at least a portion of the movable section of the carton, and moving the movable section from the first position to the second position to form a shape of the carton by heating the heat-shrinkable film to shrink the heat-shrinkable film into contact with at least a portion of the movable section. | 09-09-2010 |
Richard R. Ryan, Yardley, PA US
Patent application number | Description | Published |
---|---|---|
20080249122 | 1,3,8-TRISUBSTITUTED-1,3,8-TRIAZA-SPIRO[4.5]DECAN-4-ONE DERIVATIVES AS LIGANDS OF THE ORL-1 RECEPTOR - The present invention is directed to novel 1,3,8-trisubstituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions mediated by the ORL-1 G-protein coupled receptor. | 10-09-2008 |
Timothy Ryan, Pittsburgh, PA US
Patent application number | Description | Published |
---|---|---|
20150088183 | SURGICAL TOOL MONITORING SYSTEM AND METHODS OF USE - A device for simultaneously monitoring the health of surgical drills and detecting proximity to critical structures during surgery is described herein. By using various sensors (e.g. microphones, accelerometers, temperature sensors, etc.), signals from the drill can be measured and analyzed. The processed signals can then be used to indicate the proximity of the drill bit to critical structures, such as the patient's brain, and identify drill health issues (e.g. worn bearings, misaligned rotational axis, etc.). | 03-26-2015 |
Tracy Ryan, Wayne, PA US
Patent application number | Description | Published |
---|---|---|
20130042383 | Convertible Clothing Article with Containment Pouch - A convertible article of clothing with a compartmented hood section adapted to accept the entire garment therein and provide a carrying pouch for a user. The article comprises a hooded garment, such as a sweatshirt or jacket, wherein the hood acts as a head covering and a convertible pouch with zipper closure. The hood comprises an internal lining which is not visible when in a closed position, and is operably accessed via a vertical zipper closure. When in an open position, the lining is exposed and the hood may be turned inside out to allow the entire garment to fold into the lining. The condensed garment then becomes a satchel, which allows improved storage or transport. The lining is optionally water and stain resistant to offer a level of protection for the garment when in a stowed position. | 02-21-2013 |