Patent application number | Description | Published |
20110160092 | Methods for Selecting a Collection of Single Nucleotide Polymorphisms - The invention relates to the selection of a collection of relevant single nucleotide polymorphisms across a genome to design a nucleic acid probe array. As such, the invention relates to diverse fields impacted by the nature of genetics, including biology, medicine, and medical diagnostics. | 06-30-2011 |
20110246085 | System, method, and computer software for the presentation and storage of analysis results - A computer program product, and related systems and methods, are described that processes emission intensity data corresponding to probes of a biological probe array. The computer program includes a genotype and statistical analysis manager that determines absolute or relative expression values based, at least in part, on a statistical measure of the emission intensity data and at least one user-selectable statistical parameter. The analysis manager may also determine genotype calls for one or more probes based, at least in part, on the emission intensity data. The analysis manager may further display the absolute or relative expression values based, at least in part, on at least one user-selectable display parameter and/or a measure of normalized change between genotype calls. The measure of normalized change may be based, at least in part, on a comparison of genotype calls and a reference value. | 10-06-2011 |
20120071328 | Complexity management of Genomic DNA - The presently claimed invention provides for novel methods and kits for analyzing a collection of target sequences in a nucleic acid sample. A sample is amplified under conditions that enrich for a subset of fragments that includes a collection of target sequences. The invention further provides for analysis of the above sample by hybridization to an array, which may be specifically designed to interrogate the collection of target sequences for particular characteristics, such as, for example, the presence or absence of one or more polymorphisms. | 03-22-2012 |
20120083417 | NATIVE-EXTENSION PARALLEL SEQUENCING - The present invention provides methods for native extension parallel sequencing of polynucleotide. | 04-05-2012 |
20120252682 | METHODS AND SYSTEMS FOR SEQUENCING NUCLEIC ACIDS - The present invention provides methods and systems for sequencing long nucleic acid fragments. | 10-04-2012 |
20130045872 | METHODS OF TARGETED SEQUENCING - The present invention provides methods for targeted sequencing of polynucleotide. In one aspect, the present invention provides a method of sequencing a target polynucleotide with fewer probes. In another aspect, the present invention provides a method of sequencing a target polynucleotide with longer reads. Locus-specific, ligation-assisted sequencing/genotyping method and ligation-captured sequencing method are also provided in the present invention. The methods of the present invention allow low-cost, high-throughput and accurate sequencing of nucleic acids. | 02-21-2013 |
20130137583 | Complexity Management of Genomic DNA - The presently claimed invention provides for novel methods and kits for analyzing a collection of target sequences in a nucleic acid sample. A sample is amplified under conditions that enrich for a subset of fragments that includes a collection of target sequences. The invention further provides for analysis of the above sample by hybridization to an array, which may be specifically designed to interrogate the collection of target sequences for particular characteristics, such as, for example, the presence or absence of one or more polymorphisms. | 05-30-2013 |
20140065604 | METHODS AND SYSTEMS FOR SEQUENCING LONG NUCLEIC ACIDS - The present invention provides methods and systems for sequencing long nucleic acid fragments. | 03-06-2014 |
20140315724 | METHODS AND SYSTEMS FOR SEQUENCING LONG NUCLEIC ACIDS - The present invention provides methods and systems for sequencing long nucleic acid fragments. In one aspect of the invention, methods, systems and reagent kits are provided for sequencing nucleic acid target sequences. Some embodiments of the methods, systems and reagent kits are particularly suitable for sequencing a large number of fragments, particularly long fragments. | 10-23-2014 |
20150017632 | Complexity Management of Genomic DNA - The presently claimed invention provides for novel methods and kits for analyzing a collection of target sequences in a nucleic acid sample. A sample is amplified under conditions that enrich for a subset of fragments that includes a collection of target sequences. The invention further provides for analysis of the above sample by hybridization to an array, which may be specifically designed to interrogate the collection of target sequences for particular characteristics, such as, for example, the presence or absence of one or more polymorphisms. | 01-15-2015 |