Patent application number | Description | Published |
20080213807 | Methods of Using Bone Morphogenic Proteins as Biomarkers for Determining Cartilage Degeneration and Aging - Methods are provided for determining cartilage degeneration, regeneration, or aging in a joint tissue in a patient by measuring levels of osteogenic protein-1 (OP-1) protein and/or mRNA in synovial fluid or joint tissue. The methods according to the invention are useful for detecting, diagnosing, predicting, determining a predisposition for, or monitoring joint tissue degeneration, regeneration, or aging in a patient including inflammatory joint disease or age-related disorders. | 09-04-2008 |
20080233170 | Osteogenic Proteins - Disclosed are (1) osteogenic devices comprising a matrix containing substantially pure natural-sourced mammalian osteogenic protein; (2) DNA and amino acid sequences for novel polypeptide chains useful as subunits of dimeric osteogenic proteins; (3) vectors carrying sequences encoding these novel polypeptide chains and host cells transfected with these vectors; (4) methods of producing these polypeptide chains using recombinant DNA technology; (5) antibodies specific for these novel polypeptide chains; (6) osteogenic devices comprising these recombinantly produced proteins in association with an appropriate carrier matrix; and (7) methods of using the osteogenic devices to mimic the natural course of endochondral bone formation in mammals. | 09-25-2008 |
20090060976 | Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects - Disclosed herein are improved osteogenic devices and methods of use thereof for repair of bone and cartilage defects. The devices and methods promote accelerated formation of repair tissue with enhanced stability using less osteogenic protein than devices in the art. Defects susceptible to repair with the instant invention include, but are not limited to: critical size defects, non-critical size defects, non-union fractures, fractures, osteochondral defects, subchondral defects, and defects resulting from degenerative diseases such as osteochondritis dessicans. | 03-05-2009 |
20090169592 | Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects - Disclosed herein are improved osteogenic devices and methods of use thereof for repair of bone and cartilage defects. The devices and methods promote accelerated formation of repair tissue with enhanced stability using less osteogenic protein than devices in the art. Defects susceptible to repair with the instant invention include, but are not limited to: critical size defects, non-critical size defects, non-union fractures, fractures, osteochondral defects, subchondral defects, and defects resulting from degenerative diseases such as osteochondritis dessicans. | 07-02-2009 |
20110177135 | METHODS OF TREATING CARTILAGE DEFECTS - The present invention provides methods of repairing and regenerating cartilage tissue by administering into the cartilage or the area surrounding the cartilage a composition comprising a therapeutically effective amount of a morphogenic protein. | 07-21-2011 |
20110201556 | METHODS OF TREATING CARTILAGE DEFECTS - The present invention provides methods of repairing and regenerating cartilage tissue by administering into the cartilage or the area surrounding the cartilage a composition comprising a therapeutically effective amount of a morphogenic protein. | 08-18-2011 |
20120077743 | METHODS OF TREATING CARTILAGE DEFECTS - The present invention provides methods of repairing and regenerating cartilage tissue by administering into the cartilage or the area surrounding the cartilage a composition comprising a therapeutically effective amount of a morphogenic protein. | 03-29-2012 |
20130149294 | OSTEOGENIC DEVICES AND METHODS OF USE THEREOF FOR REPAIR OF ENDOCHONDRAL BONE, OSTEOCHONDRAL AND CHONDRAL DEFECTS - Disclosed herein are improved osteogenic devices and methods of use thereof for repair of bone and cartilage defects. The devices and methods promote accelerated formation of repair tissue with enhanced stability using less osteogenic protein than devices in the art. Defects susceptible to repair with the instant invention include, but are not limited to: critical size defects, non-critical size defects, non-union fractures, fractures, osteochondral defects, subchondral defects, and detects resulting from degenerative diseases such as osteochondritis dessicans. | 06-13-2013 |
20130231284 | METHODS OF TREATING CARTILAGE DEFECTS - The present invention provides methods of repairing and regenerating cartilage tissue by administering into the cartilage or the area surrounding the cartilage a composition comprising a therapeutically effective amount of a morphogenic protein. | 09-05-2013 |
Patent application number | Description | Published |
20090015160 | Plasma-Generating Structures, Display Devices, Plasma-Enhanced Treatments, Methods Of Forming Plasma-Generating Structures; Methods Of Plasma-Assisted Etching, And Methods Of Plasma-Assisted Deposition - Some embodiments include methods of forming plasma-generating microstructures. Aluminum may be anodized to form an aluminum oxide body having a plurality of openings extending therethrough. Conductive liners may be formed within the openings, and circuitry may be formed to control current flow through the conductive liners. The conductive liners form a plurality of hollow cathodes, and the current flow is configured to generate and maintain plasmas within the hollow cathodes. The plasmas within various hollow cathodes, or sets of hollow cathodes, may be independently controlled. Such independently controlled plasmas may be utilized to create a pattern in a display, or on a substrate. In some embodiments, the plasmas may be utilized for plasma-assisted etching and/or plasma-assisted deposition. Some embodiments include constructions and assemblies containing multiple plasma-generating structures. | 01-15-2009 |
20090239389 | Method of Forming a Layer of Material Using an Atomic Layer Deposition Process - Disclosed is a method of forming a layer of material using an atomic layer deposition (ALD) process in a process chamber of a process tool. In one illustrative embodiment, the method includes identifying a target characteristic for the layer of material, determining a precursor pulse time for introducing a precursor gas into the process chamber during the ALD process to produce the target characteristic in the layer of material, and performing the ALD process that comprises a plurality of steps wherein the precursor gas is introduced into the chamber for the determined precursor pulse time to thereby form the layer of material. | 09-24-2009 |
20090308312 | Devices for positioning carbon nanoparticles, and systems for controlling placement of nanoparticles - The present invention is generally directed to a system for controlling placement of nanoparticles, and methods of using same. In one illustrative embodiment, the device includes a substrate and a plurality of funnels in the substrate, wherein each of the funnels comprises an inlet opening and an elongated, rectangular shaped outlet opening. In one illustrative embodiment, the method includes creating a dusty plasma comprising a plurality of carbon nanotubes, positioning a mask between the dusty plasma and a desired target for the carbon nanotubes, the mask having a plurality of openings extending therethrough, and extinguishing the dusty plasma to thereby allow at least some of the carbon nanotubes in the dusty plasma to pass through at least some of the plurality of openings in the mask and land on the target. | 12-17-2009 |
20100102031 | Methods Of Forming Plasma-Generating Structures; Methods Of Plasma-Assisted Etching, And Methods Of Plasma-Assisted Deposition - Some embodiments include methods of forming plasma-generating microstructures. Aluminum may be anodized to form an aluminum oxide body having a plurality of openings extending therethrough. Conductive liners may be formed within the openings, and circuitry may be formed to control current flow through the conductive liners. The conductive liners form a plurality of hollow cathodes, and the current flow is configured to generate and maintain plasmas within the hollow cathodes. The plasmas within various hollow cathodes, or sets of hollow cathodes, may be independently controlled. Such independently controlled plasmas may be utilized to create a pattern in a display, or on a substrate. In some embodiments, the plasmas may be utilized for plasma-assisted etching and/or plasma-assisted deposition. Some embodiments include constructions and assemblies containing multiple plasma-generating structures. | 04-29-2010 |
20120001539 | Plasma-Generating Structures, Display Devices, and Methods of Forming Plasma-Generating Structures - Some embodiments include methods of forming plasma-generating microstructures. Aluminum may be anodized to form an aluminum oxide body having a plurality of openings extending therethrough. Conductive liners may be formed within the openings, and circuitry may be formed to control current flow through the conductive liners. The conductive liners form a plurality of hollow cathodes, and the current flow is configured to generate and maintain plasmas within the hollow cathodes. The plasmas within various hollow cathodes, or sets of hollow cathodes, may be independently controlled. Such independently controlled plasmas may be utilized to create a pattern in a display, or on a substrate. In some embodiments, the plasmas may be utilized for plasma-assisted etching and/or plasma-assisted deposition. Some embodiments include constructions and assemblies containing multiple plasma-generating structures. | 01-05-2012 |
20120313517 | Plasma-Generating Structures and Display Devices - Some embodiments include methods of forming plasma-generating microstructures. Aluminum may be anodized to form an aluminum oxide body having a plurality of openings extending therethrough. Conductive liners may be formed within the openings, and circuitry may be formed to control current flow through the conductive liners. The conductive liners form a plurality of hollow cathodes, and the current flow is configured to generate and maintain plasmas within the hollow cathodes. The plasmas within various hollow cathodes, or sets of hollow cathodes, may be independently controlled. Such independently controlled plasmas may be utilized to create a pattern in a display, or on a substrate. In some embodiments, the plasmas may be utilized for plasma-assisted etching and/or plasma-assisted deposition. Some embodiments include constructions and assemblies containing multiple plasma-generating structures. | 12-13-2012 |
Patent application number | Description | Published |
20110248171 | APPARATUS WITH OPTICAL FUNCTIONALITY AND ASSOCIATED METHODS - In an exemplary embodiment, an apparatus includes a sensor integrated circuit (IC). The at least one integrated photodetector that is adapted to sense light, and an integrated analog-to-digital converter (ADC). The integrated analog-to-digital converter (ADC) is coupled to the at least one integrated photodetector, and is adapted to convert an output signal of one or more of the at least one integrated photodetector to one or more digital signals. The sensor integrated circuit (IC) further includes an integrated controller that is adapted to facilitate operation of the sensor integrated circuit (IC). | 10-13-2011 |
20110248172 | APPARATUS WITH OPTICAL FUNCTIONALITY AND POWER MANAGEMENT AND ASSOCIATED METHODS - In an exemplary embodiment, an apparatus includes a sensor integrated circuit (IC) that is adapted for ambient light sensing (ALS) and/or proximity detection. The sensor integrated circuit (IC) includes an integrated analog-to-digital converter (ADC) that is adapted to convert at least one signal related to ambient light sensing (ALS) and/or proximity detection to at least one digital signal, and an integrated light emitting diode (LED) driver that is adapted to drive at least one LED. The sensor IC also includes an integrated power management unit (PMU) that is adapted to reduce power dissipation of the sensor IC by running at a low duty cycle the integrated LED driver and the integrated ADC. | 10-13-2011 |
20110249258 | APPARATUS WITH OPTICAL FUNCTIONALITY AND ASSOCIATED METHODS - In an exemplary embodiment, an apparatus includes a sensor integrated circuit (IC). The at least one integrated photodetector that is adapted to sense light, and an integrated analog-to-digital converter (ADC). The integrated analog-to-digital converter (ADC) is coupled to the at least one integrated photodetector, and is adapted to convert an output signal of one or more of the at least one integrated photodetector to one or more digital signals. The sensor integrated circuit (IC) further includes an integrated controller that is adapted to facilitate operation of the sensor integrated circuit (IC). | 10-13-2011 |
20110249369 | APPARATUS FOR PROTECTION OF ELECTRONIC CIRCUITRY AND ASSOCIATED METHODS - In an exemplary embodiment, an apparatus includes a single clamp circuit adapted to clamp an electrostatic discharge (ESD) voltage. The apparatus further includes a supply node coupled to the single clamp circuit via one diode, and a ground node that is coupled to the supply node via another diode. The ground node is also coupled to the single clamp circuit. | 10-13-2011 |
20130113524 | FLEXIBLE LOW POWER SLEW-RATE CONTROLLED OUTPUT BUFFER - An output buffer includes a pullup driver, a pulldown driver, and an output stage. The pullup driver has a drive control input, and an output for providing a pullup drive signal in a push-pull mode in response to receiving a first drive control signal on the drive control input, and in a current limited mode in response to receiving a second drive control signal on said drive control input. The pulldown driver has a drive control input, and an output for providing a pulldown drive signal in the push-pull mode in response to receiving a third drive control signal on the drive control input, and in the current limited mode in response to receiving a fourth drive control signal on the drive control input. The output stage provides a voltage on an output terminal in response to the pullup and pulldown drive signals. | 05-09-2013 |
20150122996 | Apparatus with sensor functionality and power management and associated methods - In an exemplary embodiment, an apparatus includes a sensor integrated circuit (IC) that is adapted for ambient light sensing (ALS) and/or proximity detection. The sensor integrated circuit (IC) includes an integrated analog-to-digital converter (ADC) that is adapted to convert at least one signal related to ambient light sensing (ALS) and/or proximity detection to at least one digital signal, and an integrated light emitting diode (LED) driver that is adapted to drive at least one LED. The sensor IC also includes an integrated power management unit (PMU) that is adapted to reduce power dissipation of the sensor IC by running at a low duty cycle the integrated LED driver and the integrated ADC. | 05-07-2015 |
20150235606 | LCD CONTROLLER WITH OSCILLATOR PREBIAS CONTROL - An LCD controller includes a charge pump circuit for generating a charge voltage responsive to an external voltage and a clock signal. An oscillator generates the clock signal responsive to at least one bias voltage. The oscillator has a high power mode of operation and a low power mode of operation. Bias circuitry for applies the at least one bias voltage to the oscillator. The at least one bias voltage is applied to the oscillator from an external source in the high power mode of operation and the at least one bias voltage is applied to the oscillator from a source within the oscillator in the low power mode of operation. An LCD driver voltage circuit generates a plurality of LCD driver voltages for driving segments of an LCD display responsive to the charge voltage. | 08-20-2015 |