Rubén
Rubén Alvarez Sánchez, Rosenau FR
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20100267722 | NOVEL PROLINE DERIVATIVES - The invention relates to a compound of formula (I) | 10-21-2010 |
20100317647 | NOVEL CYCLOPENTANE DERIVATIVES - The invention relates to a compound of formula (I) | 12-16-2010 |
20110071128 | NOVEL IMIDAZOPYRIDINES - The invention is concerned with novel imidazopyridine derivatives of formula (I) | 03-24-2011 |
Rubén Alvarez Sánchez, Rosenau FR
Patent application number | Description | Published |
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20100267722 | NOVEL PROLINE DERIVATIVES - The invention relates to a compound of formula (I) | 10-21-2010 |
20100317647 | NOVEL CYCLOPENTANE DERIVATIVES - The invention relates to a compound of formula (I) | 12-16-2010 |
20110071128 | NOVEL IMIDAZOPYRIDINES - The invention is concerned with novel imidazopyridine derivatives of formula (I) | 03-24-2011 |
20110237564 | IMIDAZOPYRIMIDINE DERIVATIVES - The invention is concerned with novel imidazopyrimidine derivatives of formula (I) | 09-29-2011 |
20110294779 | NOVEL IMIDAZOPYRIDINES - The invention is concerned with novel imidazopyridine derivatives of formula (I) | 12-01-2011 |
Rubén Armañanzas Arnedillo, Boadilla Del Monte ES
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20120164653 | METHODS FOR THE DIAGNOSIS OF MULTIPLE SCLEROSIS BASED ON ITS MICRORNA EXPRESSION PROFILING - The invention relates, in general, to a method for the diagnosis of multiple sclerosis based on determining amounts of one or more micro-RNAs correlated with multiple sclerosis in a biological sample from a subject. | 06-28-2012 |
Rubén Cuadrado Asensio, Valladolid ES
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20110164215 | DEVICE FOR ASSISTING AND PROTECTING VISION - The invention relates to a device comprising one left electrochromic filter ( | 07-07-2011 |
Rubén Hernández Alcoceba, Pamplona-Navarra ES
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20110070623 | SELF-INACTIVATING HELPER ADENOVIRUSES FOR THE PRODUCTION OF HIGH-CAPACTIY RECOMBINANT ADENOVIRUSES - The invention relates to reagents and methods for the generation of auto-inactivating helper adenoviruses that allow the development of cell systems for the generation of high-capacity recombinant adenovirus showing a reduced contamination by auxiliary adenoviruses. | 03-24-2011 |
Rubén Hernández Alcoceba, Pamplona-Navarra ES
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20110070623 | SELF-INACTIVATING HELPER ADENOVIRUSES FOR THE PRODUCTION OF HIGH-CAPACTIY RECOMBINANT ADENOVIRUSES - The invention relates to reagents and methods for the generation of auto-inactivating helper adenoviruses that allow the development of cell systems for the generation of high-capacity recombinant adenovirus showing a reduced contamination by auxiliary adenoviruses. | 03-24-2011 |
Rubén Lara Hernández, Madrid ES
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20130198191 | METHOD FOR DETECTING COMMUNITIES IN MASSIVE SOCIAL NETWORKS BY MEANS OF AN AGGLOMERATIVE APPROACH - Disclosed is a method for detecting communities in massive social networks by means of an agglomerative approach in which core communities are built and gradually clustered in an iterative manner into higher level communities until the algorithm converges (a stop condition is met), whereby it becomes possible to easily trace how the communities are being formed, resulting in an easily explainable model that allows the detection of overlapping communities. The disclosed method starts from data representing social interactions between individuals, building a weighted social graph where the vertices represent individuals and the links represent social relationships between individuals. | 08-01-2013 |
Rubén Martin Laguens, Prov. Bs. As. AR
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20090220622 | USE OF MIMOSINE OR A DERIVATIVE THEREOF FOR TREATING THE CUTANEOUS EFFECTS OF PSORIASIS AND RELATED SKIN DISORDERS, AND COSMETIC OR PHARMACEUTICAL COMPOSITION CONTAINING SAME - The present invention relates to the use of mimosine or a derivative thereof for treating the cutaneous effects of psoriasis and related skin disorders. | 09-03-2009 |
Rubén Martin Laguens, Prov. Bs. As. AR
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20090220622 | USE OF MIMOSINE OR A DERIVATIVE THEREOF FOR TREATING THE CUTANEOUS EFFECTS OF PSORIASIS AND RELATED SKIN DISORDERS, AND COSMETIC OR PHARMACEUTICAL COMPOSITION CONTAINING SAME - The present invention relates to the use of mimosine or a derivative thereof for treating the cutaneous effects of psoriasis and related skin disorders. | 09-03-2009 |
Rubén Martín Montaña, Valladolid ES
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20110054025 | USE OF A PENTACYCLIC TRITERPENE IN A PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF MULTIPLE SCLEROSIS - Oleanolic acid (3β-hiydroxyolean-12-en-28-oic acid) is a pentacyclic triterpene occurring in a large number of medicinal plants. The present invention is directed to the pharmacological application of the oleanolic acid, alone or in combination with other substances, in the treatment or prophylaxis of neurodegenerative diseases such as multiple sclerosis. The inventors have found that oleanolic acid, intraperitoneally administered once daily, reduces significantly the immuno-inflammatory and neurological symptoms associated with the experimental autoimmune encephalomyelitis, an experimental model of multiple sclerosis, delaying the onset and reducing the progression of the disease. | 03-03-2011 |
Rubén Martín Montaña, Valladolid ES
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20110054025 | USE OF A PENTACYCLIC TRITERPENE IN A PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF MULTIPLE SCLEROSIS - Oleanolic acid (3β-hiydroxyolean-12-en-28-oic acid) is a pentacyclic triterpene occurring in a large number of medicinal plants. The present invention is directed to the pharmacological application of the oleanolic acid, alone or in combination with other substances, in the treatment or prophylaxis of neurodegenerative diseases such as multiple sclerosis. The inventors have found that oleanolic acid, intraperitoneally administered once daily, reduces significantly the immuno-inflammatory and neurological symptoms associated with the experimental autoimmune encephalomyelitis, an experimental model of multiple sclerosis, delaying the onset and reducing the progression of the disease. | 03-03-2011 |
Rubén Mohedano, Madrid ES
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20100269885 | PHOTOVOLTAIC DEVICE - Some photovoltaic cells have a front face accepting incoming incident light and opaque gridlines overlying part of the front face, electrically bonded to the face, with upper reflective facets oblique to the plane of the front face and producing outgoing reflected light. An optical interface parallel to and in front of the front face transmits incoming light to the front face and to the gridlines and reflects back towards the front face by total internal reflection at least some of the outgoing reflected light. Some photovoltaic devices have a triple junction photovoltaic cell, a single junction photovoltaic cell, and a reflective surface arranged to distribute incoming light between the cells. The surface may be a frequency-selective mirror that apportions light so when the cells are in series the power produced, and preferably the photocurrent, is greater than if all the light fell on the triple junction cell alone. | 10-28-2010 |
Rubén Mohedano, Madrid ES
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20080316761 | Free-Form Lenticular Optical Elements and Their Application to Condensers and Headlamps - Some embodiments provide an illumination optical system. The optical system can include a first surface and a second surface. Each of the first and second surfaces can further comprises a multiplicity of corresponding Cartesian-oval lenticulations such that each lenticulation of the first surface focuses a source upon a corresponding lenticulation of the second surface and each lenticulation of the second surface focuses a target upon a corresponding lenticulation of the first surface. | 12-25-2008 |
20090071467 | MULTI-JUNCTION SOLAR CELLS WITH A HOMOGENIZER SYSTEM AND COUPLED NON-IMAGING LIGHT CONCENTRATOR - The present embodiments provide methods and systems to homogenize illumination on a target. Some embodiments provide rotational symmetric dual-reflector solar concentrators that include a concave primary reflector with an aim-direction directed toward the sun to receive optical radiation in a far-field angle within an angle of acceptance and redirect radiation upward and centrally generating flux concentration, a secondary reflector positioned coaxial with said primary reflector to receive said redirected radiation and redirect radiation downward and centrally generating flux concentration solar rays, and a central target zone receiving said concentrated solar rays, where cross sections of said primary and secondary reflectors both further comprise a multiplicity of segments that establish a correspondence between pairs of segments, each of said segments of said primary reflector such as to image said angle of acceptance onto said corresponding segment of said secondary reflector to image onto said target zone. | 03-19-2009 |
20100269885 | PHOTOVOLTAIC DEVICE - Some photovoltaic cells have a front face accepting incoming incident light and opaque gridlines overlying part of the front face, electrically bonded to the face, with upper reflective facets oblique to the plane of the front face and producing outgoing reflected light. An optical interface parallel to and in front of the front face transmits incoming light to the front face and to the gridlines and reflects back towards the front face by total internal reflection at least some of the outgoing reflected light. Some photovoltaic devices have a triple junction photovoltaic cell, a single junction photovoltaic cell, and a reflective surface arranged to distribute incoming light between the cells. The surface may be a frequency-selective mirror that apportions light so when the cells are in series the power produced, and preferably the photocurrent, is greater than if all the light fell on the triple junction cell alone. | 10-28-2010 |
Rubén Pío, Pamplona ES
Patent application number | Description | Published |
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20090053734 | DETERMINATION OF AM-BINDING PROTEINS AND THE ASSOCIATION OF ADRENOMEDULLIN (AM) THEREWITH - The present invention provides methods for the isolation, identification, and purification of adrenomedullin (AM)-binding proteins. Also, provided are methods for utilizing the purified AM-binding proteins, or functional portions thereof, to diagnose, treat, and monitor AM-related diseases, for example, diseases or disorders associated with abnormally elevated AM levels. In addition, the present invention provides a newly identified complex between AM and a specific AM-binding protein 1 (AMBP-1); which has been isolated and identified herein as factor H (fH). The invention also provides AM/AMBP complexes, particularly AM/FH complexes, and antibodies specifically reactive with this complexes. Further provided are methods for identifying and purifying complexes of AM and an AM binding protein using anti-AM/fH antibodies, and methods for treating conditions such as cancer or diabetes utilizing compositions comprising these antibodies. The present invention additionally provides methods for identifying antagonists agents that inhibit the function of AM, factor H, or the AM/factor H complex. The invention also provides methods for treating conditions such as cancer or diabetes using these antagonist agents. | 02-26-2009 |
20100098703 | DETERMINATION OF AM-BINDING PROTEINS AND THE ASSOCIATION OF ADRENOMEDULLIN (AM) THEREWITH - The present invention provides methods for the isolation, identification, and purification of adrenomedullin (AM)-binding proteins. Also, provided are methods for utilizing the purified AM-binding proteins, or functional portions thereof, to diagnose, treat, and monitor AM-related diseases, for example, diseases or disorders associated with abnormally elevated AM levels. In addition, the present invention provides a newly identified complex between AM and a specific AM-binding protein 1 (AMBP-1); which has been isolated and identified herein as factor H (fH). The invention also provides AM/AMBP complexes, particularly AM/FH complexes, and antibodies specifically reactive with this complexes. Further provided are methods for identifying and purifying complexes of AM and an AM binding protein using anti-AM/fH antibodies, and methods for treating conditions such as cancer or diabetes utilizing compositions comprising these antibodies. The present invention additionally provides methods for identifying antagonists agents that inhibit the function of AM, factor H, or the AM/factor H complex. The invention also provides methods for treating conditions such as cancer or diabetes using these antagonist agents. | 04-22-2010 |
Rubén Pío, Pamplona ES
Patent application number | Description | Published |
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20100098703 | DETERMINATION OF AM-BINDING PROTEINS AND THE ASSOCIATION OF ADRENOMEDULLIN (AM) THEREWITH - The present invention provides methods for the isolation, identification, and purification of adrenomedullin (AM)-binding proteins. Also, provided are methods for utilizing the purified AM-binding proteins, or functional portions thereof, to diagnose, treat, and monitor AM-related diseases, for example, diseases or disorders associated with abnormally elevated AM levels. In addition, the present invention provides a newly identified complex between AM and a specific AM-binding protein 1 (AMBP-1); which has been isolated and identified herein as factor H (fH). The invention also provides AM/AMBP complexes, particularly AM/FH complexes, and antibodies specifically reactive with this complexes. Further provided are methods for identifying and purifying complexes of AM and an AM binding protein using anti-AM/fH antibodies, and methods for treating conditions such as cancer or diabetes utilizing compositions comprising these antibodies. The present invention additionally provides methods for identifying antagonists agents that inhibit the function of AM, factor H, or the AM/factor H complex. The invention also provides methods for treating conditions such as cancer or diabetes using these antagonist agents. | 04-22-2010 |
Rubén Trapero Burgos, Alcorcon (madrid) ES
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20130173712 | METHOD FOR SELECTIVELY DISTRIBUTING INFORMATION IN A COMPUTER OR COMMUNICATION NETWORK, AND PHYSICAL ENTITIES THEREFOR - A method is carried out by a controller ( | 07-04-2013 |
Rubén Villarino-Villa, Muenchen DE
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20100141308 | METHOD AND DEVICE FOR CLOCK-DATA RECOVERY - A method for the recovery of a clock signal from a data signal is provided where the edges of the signals are each represented as a chronologically-ordered sequence of timing points. In one procedural stage, a plurality of timing points of the data signal are processed in parallel as follows: resolving the timing points of the data signal by a nominal clock pulse; estimating the bit-period deviations for the adjusted timing points; and injecting the nominal clock pulse to the estimated bit-period deviations. | 06-10-2010 |